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Items: 8

1.

Unique pharmacology of a novel allosteric agonist/sensitizer insulin receptor monoclonal antibody.

Hinke SA, Cieniewicz AM, Kirchner T, D'Aquino K, Nanjunda R, Aligo J, Perkinson R, Cooper P, Boayke K, Chiu ML, Jarantow S, Lacy ER, Liang Y, Johnson DL, Whaley JM, Lingham RB, Kihm AJ.

Mol Metab. 2018 Apr;10:87-99. doi: 10.1016/j.molmet.2018.01.014. Epub 2018 Feb 3.

2.

Novel Monoclonal Antibody Is an Allosteric Insulin Receptor Antagonist That Induces Insulin Resistance.

Cieniewicz AM, Kirchner T, Hinke SA, Nanjunda R, D'Aquino K, Boayke K, Cooper PR, Perkinson R, Chiu ML, Jarantow S, Johnson DL, Whaley JM, Lacy ER, Lingham RB, Liang Y, Kihm AJ.

Diabetes. 2017 Jan;66(1):206-217. doi: 10.2337/db16-0633. Epub 2016 Oct 26.

3.

Novel method demonstrates differential ligand activation and phosphatase-mediated deactivation of insulin receptor tyrosine-specific phosphorylation.

Cieniewicz AM, Cooper PR, McGehee J, Lingham RB, Kihm AJ.

Cell Signal. 2016 Aug;28(8):1037-47. doi: 10.1016/j.cellsig.2016.05.001. Epub 2016 May 4.

PMID:
27155325
4.

Nucleosome competition reveals processive acetylation by the SAGA HAT module.

Ringel AE, Cieniewicz AM, Taverna SD, Wolberger C.

Proc Natl Acad Sci U S A. 2015 Oct 6;112(40):E5461-70. doi: 10.1073/pnas.1508449112. Epub 2015 Sep 23.

5.

The bromodomain of Gcn5 regulates site specificity of lysine acetylation on histone H3.

Cieniewicz AM, Moreland L, Ringel AE, Mackintosh SG, Raman A, Gilbert TM, Wolberger C, Tackett AJ, Taverna SD.

Mol Cell Proteomics. 2014 Nov;13(11):2896-910. doi: 10.1074/mcp.M114.038174. Epub 2014 Aug 8.

6.

A selective phenelzine analogue inhibitor of histone demethylase LSD1.

Prusevich P, Kalin JH, Ming SA, Basso M, Givens J, Li X, Hu J, Taylor MS, Cieniewicz AM, Hsiao PY, Huang R, Roberson H, Adejola N, Avery LB, Casero RA Jr, Taverna SD, Qian J, Tackett AJ, Ratan RR, McDonald OG, Feinberg AP, Cole PA.

ACS Chem Biol. 2014 Jun 20;9(6):1284-93. doi: 10.1021/cb500018s. Epub 2014 Apr 7.

7.

Passage through vertebrate gap junctions of 17/18kDa molecules is primarily dependent upon molecular configuration.

Cieniewicz AM, Woodruff RI.

Tissue Cell. 2010 Feb;42(1):47-52. doi: 10.1016/j.tice.2009.07.003. Epub 2009 Sep 1.

PMID:
19726067
8.

Importance of molecular configuration in gap junctional permeability.

Cieniewicz AM, Woodruff RI.

J Insect Physiol. 2008 Aug;54(8):1293-300. doi: 10.1016/j.jinsphys.2008.06.012. Epub 2008 Jul 23.

PMID:
18691596

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