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Items: 1 to 50 of 317

1.

Muscle-specific regulation of right ventricular transcriptional responses to chronic hypoxia-induced hypertrophy by the muscle ring finger-1 (MuRF1) ubiquitin ligase in mice.

Oakley RH, Campen MJ, Paffett ML, Chen X, Wang Z, Parry TL, Hillhouse C, Cidlowski JA, Willis MS.

BMC Med Genet. 2018 Sep 21;19(1):175. doi: 10.1186/s12881-018-0670-1.

2.

MicroRNA Profiling and Bioinformatics Target Analysis in Dorsal Hippocampus of Chronically Stressed Rats: Relevance to Depression Pathophysiology.

Muñoz-Llanos M, García-Pérez MA, Xu X, Tejos-Bravo M, Vidal EA, Moyano TC, Gutiérrez RA, Aguayo FI, Pacheco A, García-Rojo G, Aliaga E, Rojas PS, Cidlowski JA, Fiedler JL.

Front Mol Neurosci. 2018 Aug 6;11:251. doi: 10.3389/fnmol.2018.00251. eCollection 2018.

3.

Glucocorticoid Receptor Mutations and Hypersensitivity to Endogenous and Exogenous Glucocorticoids.

Santen RJ, Jewell CM, Yue W, Heitjan DF, Raff H, Katen KS, Cidlowski JA.

J Clin Endocrinol Metab. 2018 Oct 1;103(10):3630-3639. doi: 10.1210/jc.2018-00352.

PMID:
30020469
4.

Taxol Induces Brk-dependent Prosurvival Phenotypes in TNBC Cells through an AhR/GR/HIF-driven Signaling Axis.

Regan Anderson TM, Ma S, Perez Kerkvliet C, Peng Y, Helle TM, Krutilina RI, Raj GV, Cidlowski JA, Ostrander JH, Schwertfeger KL, Seagroves TN, Lange CA.

Mol Cancer Res. 2018 Nov;16(11):1761-1772. doi: 10.1158/1541-7786.MCR-18-0410. Epub 2018 Jul 10.

PMID:
29991529
5.

Glucocorticoids Impair Phagocytosis and Inflammatory Response Against Crohn's Disease-Associated Adherent-Invasive Escherichia coli.

Olivares-Morales MJ, De La Fuente MK, Dubois-Camacho K, Parada D, Diaz-Jiménez D, Torres-Riquelme A, Xu X, Chamorro-Veloso N, Naves R, Gonzalez MJ, Quera R, Figueroa C, Cidlowski JA, Vidal RM, Hermoso MA.

Front Immunol. 2018 May 16;9:1026. doi: 10.3389/fimmu.2018.01026. eCollection 2018.

6.

Glucocorticoid receptor isoform-specific regulation of development, circadian rhythm, and inflammation in mice.

Oakley RH, Ramamoorthy S, Foley JF, Busada JT, Lu NZ, Cidlowski JA.

FASEB J. 2018 Oct;32(10):5258-5271. doi: 10.1096/fj.201701153R. Epub 2018 Apr 19.

PMID:
29672221
7.

Neonatal Genistein Exposure and Glucocorticoid Signaling in the Adult Mouse Uterus.

Whirledge SD, Kisanga EP, Oakley RH, Cidlowski JA.

Environ Health Perspect. 2018 Apr 5;126(4):047002. doi: 10.1289/EHP1575.

8.

Estrogen Deficiency Promotes Hepatic Steatosis via a Glucocorticoid Receptor-Dependent Mechanism in Mice.

Quinn MA, Xu X, Ronfani M, Cidlowski JA.

Cell Rep. 2018 Mar 6;22(10):2690-2701. doi: 10.1016/j.celrep.2018.02.041.

9.

Probing Dominant Negative Behavior of Glucocorticoid Receptor β through a Hybrid Structural and Biochemical Approach.

Min J, Perera L, Krahn JM, Jewell CM, Moon AF, Cidlowski JA, Pedersen LC.

Mol Cell Biol. 2018 Feb 5. pii: MCB.00453-17. doi: 10.1128/MCB.00453-17. [Epub ahead of print]

10.

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Galluzzi L, Vitale I, Aaronson SA, Abrams JM, Adam D, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Annicchiarico-Petruzzelli M, Antonov AV, Arama E, Baehrecke EH, Barlev NA, Bazan NG, Bernassola F, Bertrand MJM, Bianchi K, Blagosklonny MV, Blomgren K, Borner C, Boya P, Brenner C, Campanella M, Candi E, Carmona-Gutierrez D, Cecconi F, Chan FK, Chandel NS, Cheng EH, Chipuk JE, Cidlowski JA, Ciechanover A, Cohen GM, Conrad M, Cubillos-Ruiz JR, Czabotar PE, D'Angiolella V, Dawson TM, Dawson VL, De Laurenzi V, De Maria R, Debatin KM, DeBerardinis RJ, Deshmukh M, Di Daniele N, Di Virgilio F, Dixit VM, Dixon SJ, Duckett CS, Dynlacht BD, El-Deiry WS, Elrod JW, Fimia GM, Fulda S, García-Sáez AJ, Garg AD, Garrido C, Gavathiotis E, Golstein P, Gottlieb E, Green DR, Greene LA, Gronemeyer H, Gross A, Hajnoczky G, Hardwick JM, Harris IS, Hengartner MO, Hetz C, Ichijo H, Jäättelä M, Joseph B, Jost PJ, Juin PP, Kaiser WJ, Karin M, Kaufmann T, Kepp O, Kimchi A, Kitsis RN, Klionsky DJ, Knight RA, Kumar S, Lee SW, Lemasters JJ, Levine B, Linkermann A, Lipton SA, Lockshin RA, López-Otín C, Lowe SW, Luedde T, Lugli E, MacFarlane M, Madeo F, Malewicz M, Malorni W, Manic G, Marine JC, Martin SJ, Martinou JC, Medema JP, Mehlen P, Meier P, Melino S, Miao EA, Molkentin JD, Moll UM, Muñoz-Pinedo C, Nagata S, Nuñez G, Oberst A, Oren M, Overholtzer M, Pagano M, Panaretakis T, Pasparakis M, Penninger JM, Pereira DM, Pervaiz S, Peter ME, Piacentini M, Pinton P, Prehn JHM, Puthalakath H, Rabinovich GA, Rehm M, Rizzuto R, Rodrigues CMP, Rubinsztein DC, Rudel T, Ryan KM, Sayan E, Scorrano L, Shao F, Shi Y, Silke J, Simon HU, Sistigu A, Stockwell BR, Strasser A, Szabadkai G, Tait SWG, Tang D, Tavernarakis N, Thorburn A, Tsujimoto Y, Turk B, Vanden Berghe T, Vandenabeele P, Vander Heiden MG, Villunger A, Virgin HW, Vousden KH, Vucic D, Wagner EF, Walczak H, Wallach D, Wang Y, Wells JA, Wood W, Yuan J, Zakeri Z, Zhivotovsky B, Zitvogel L, Melino G, Kroemer G.

Cell Death Differ. 2018 Mar;25(3):486-541. doi: 10.1038/s41418-017-0012-4. Epub 2018 Jan 23. Review.

11.

Pharmacology of Corticosteroids for Diabetic Macular Edema.

Whitcup SM, Cidlowski JA, Csaky KG, Ambati J.

Invest Ophthalmol Vis Sci. 2018 Jan 1;59(1):1-12. doi: 10.1167/iovs.17-22259. Review.

12.

Glucocorticoid receptor signaling in the eye.

Sulaiman RS, Kadmiel M, Cidlowski JA.

Steroids. 2018 May;133:60-66. doi: 10.1016/j.steroids.2017.11.002. Epub 2017 Nov 10. Review.

13.

LPS regulates the expression of glucocorticoid receptor α and β isoforms and induces a selective glucocorticoid resistance in vitro.

Molina ML, Guerrero J, Cidlowski JA, Gatica H, Goecke A.

J Inflamm (Lond). 2017 Oct 16;14:22. doi: 10.1186/s12950-017-0169-0. eCollection 2017.

14.

THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Overview.

Alexander SP, Kelly E, Marrion NV, Peters JA, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Buneman OP, Cidlowski JA, Christopoulos A, Davenport AP, Fabbro D, Spedding M, Striessnig J, Davies JA; CGTP Collaborators.

Br J Pharmacol. 2017 Dec;174 Suppl 1:S1-S16. doi: 10.1111/bph.13882.

15.

THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Nuclear hormone receptors.

Alexander SP, Cidlowski JA, Kelly E, Marrion NV, Peters JA, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators.

Br J Pharmacol. 2017 Dec;174 Suppl 1:S208-S224. doi: 10.1111/bph.13880.

16.

Pioneer Factors FOXA1 and FOXA2 Assist Selective Glucocorticoid Receptor Signaling in Human Endometrial Cells.

Whirledge S, Kisanga EP, Taylor RN, Cidlowski JA.

Endocrinology. 2017 Nov 1;158(11):4076-4092. doi: 10.1210/en.2017-00361.

17.

A functional IL1RL1 variant regulates corticosteroid-induced sST2 expression in ulcerative colitis.

Díaz-Jiménez D, Núñez L, De la Fuente M, Dubois-Camacho K, Sepúlveda H, Montecino M, Torres-Riquelme A, García-González P, Chnaiderman J, Vossenkamper A, MacDonald TT, Simian D, González MJ, Cidlowski JA, Quera R, Hermoso MA.

Sci Rep. 2017 Aug 31;7(1):10180. doi: 10.1038/s41598-017-10465-0.

18.

Generating diversity in human glucocorticoid signaling through a racially diverse polymorphism in the beta isoform of the glucocorticoid receptor.

Whirledge SD, Jewell CM, Barber LM, Xu X, Katen KS, Garantziotis S, Cidlowski JA.

Lab Invest. 2017 Nov;97(11):1282-1295. doi: 10.1038/labinvest.2017.76. Epub 2017 Jul 31.

19.

Mechanisms of Glucocorticoid Action During Development.

Busada JT, Cidlowski JA.

Curr Top Dev Biol. 2017;125:147-170. doi: 10.1016/bs.ctdb.2016.12.004. Epub 2017 Jan 16. Review.

PMID:
28527570
20.

Glucocorticoids and Reproduction: Traffic Control on the Road to Reproduction.

Whirledge S, Cidlowski JA.

Trends Endocrinol Metab. 2017 Jun;28(6):399-415. doi: 10.1016/j.tem.2017.02.005. Epub 2017 Mar 6. Review.

21.
22.

Immune regulation by glucocorticoids.

Cain DW, Cidlowski JA.

Nat Rev Immunol. 2017 Apr;17(4):233-247. doi: 10.1038/nri.2017.1. Epub 2017 Feb 13. Review.

PMID:
28192415
23.

Healthy glucocorticoid receptor N363S carriers dysregulate gene expression associated with metabolic syndrome.

Jewell CM, Katen KS, Barber LM, Cannon C, Garantziotis S, Cidlowski JA.

Am J Physiol Endocrinol Metab. 2016 Oct 1;311(4):E741-E748. doi: 10.1152/ajpendo.00105.2016. Epub 2016 Sep 6.

24.

Glucocorticoid action in human corneal epithelial cells establishes roles for corticosteroids in wound healing and barrier function of the eye.

Kadmiel M, Janoshazi A, Xu X, Cidlowski JA.

Exp Eye Res. 2016 Nov;152:10-33. doi: 10.1016/j.exer.2016.08.020. Epub 2016 Sep 4.

25.

Krüppel-like Factor 13 Is a Major Mediator of Glucocorticoid Receptor Signaling in Cardiomyocytes and Protects These Cells from DNA Damage and Death.

Cruz-Topete D, He B, Xu X, Cidlowski JA.

J Biol Chem. 2016 Sep 9;291(37):19374-86. doi: 10.1074/jbc.M116.725903. Epub 2016 Jul 22.

26.

Corticosteroids Are Essential for Maintaining Cardiovascular Function in Male Mice.

Cruz-Topete D, Myers PH, Foley JF, Willis MS, Cidlowski JA.

Endocrinology. 2016 Jul;157(7):2759-71. doi: 10.1210/en.2015-1604. Epub 2016 May 24.

27.

MiR-16 mediates trastuzumab and lapatinib response in ErbB-2-positive breast and gastric cancer via its novel targets CCNJ and FUBP1.

Venturutti L, Cordo Russo RI, Rivas MA, Mercogliano MF, Izzo F, Oakley RH, Pereyra MG, De Martino M, Proietti CJ, Yankilevich P, Roa JC, Guzmán P, Cortese E, Allemand DH, Huang TH, Charreau EH, Cidlowski JA, Schillaci R, Elizalde PV.

Oncogene. 2016 Dec 1;35(48):6189-6202. doi: 10.1038/onc.2016.151. Epub 2016 May 9.

28.

Breast Tumor Kinase (Brk/PTK6) Is Induced by HIF, Glucocorticoid Receptor, and PELP1-Mediated Stress Signaling in Triple-Negative Breast Cancer.

Regan Anderson TM, Ma SH, Raj GV, Cidlowski JA, Helle TM, Knutson TP, Krutilina RI, Seagroves TN, Lange CA.

Cancer Res. 2016 Mar 15;76(6):1653-63. doi: 10.1158/0008-5472.CAN-15-2510. Epub 2016 Jan 29.

29.

Human Glucocorticoid Receptor β Regulates Gluconeogenesis and Inflammation in Mouse Liver.

He B, Cruz-Topete D, Oakley RH, Xiao X, Cidlowski JA.

Mol Cell Biol. 2015 Dec 28;36(5):714-30. doi: 10.1128/MCB.00908-15.

30.

T-cell development of resistance to apoptosis is driven by a metabolic shift in carbon source and altered activation of death pathways.

Bortner CD, Scoltock AB, Cain DW, Cidlowski JA.

Cell Death Differ. 2016 May;23(5):889-902. doi: 10.1038/cdd.2015.156. Epub 2015 Dec 11.

31.

The Concise Guide to PHARMACOLOGY 2015/16: Nuclear hormone receptors.

Alexander SP, Cidlowski JA, Kelly E, Marrion N, Peters JA, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators.

Br J Pharmacol. 2015 Dec;172(24):5956-78. doi: 10.1111/bph.13352.

32.

The Concise Guide to PHARMACOLOGY 2015/16: Overview.

Alexander SP, Kelly E, Marrion N, Peters JA, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Southan C, Buneman OP, Catterall WA, Cidlowski JA, Davenport AP, Fabbro D, Fan G, McGrath JC, Spedding M, Davies JA; CGTP Collaborators.

Br J Pharmacol. 2015 Dec;172(24):5729-43. doi: 10.1111/bph.13347.

33.

Corticosteroids: Mechanisms of Action in Health and Disease.

Ramamoorthy S, Cidlowski JA.

Rheum Dis Clin North Am. 2016 Feb;42(1):15-31, vii. doi: 10.1016/j.rdc.2015.08.002. Review.

34.

Uterine glucocorticoid receptors are critical for fertility in mice through control of embryo implantation and decidualization.

Whirledge SD, Oakley RH, Myers PH, Lydon JP, DeMayo F, Cidlowski JA.

Proc Natl Acad Sci U S A. 2015 Dec 8;112(49):15166-71. doi: 10.1073/pnas.1508056112. Epub 2015 Nov 23.

35.

Endogenous hepatic glucocorticoid receptor signaling coordinates sex-biased inflammatory gene expression.

Quinn MA, Cidlowski JA.

FASEB J. 2016 Feb;30(2):971-82. doi: 10.1096/fj.15-278309. Epub 2015 Nov 18.

36.

Specificity and sensitivity of glucocorticoid signaling in health and disease.

Cain DW, Cidlowski JA.

Best Pract Res Clin Endocrinol Metab. 2015 Aug;29(4):545-56. doi: 10.1016/j.beem.2015.04.007. Epub 2015 Apr 25. Review.

37.

Neuroimmune mechanisms of stress: sex differences, developmental plasticity, and implications for pharmacotherapy of stress-related disease.

Deak T, Quinn M, Cidlowski JA, Victoria NC, Murphy AZ, Sheridan JF.

Stress. 2015;18(4):367-80. doi: 10.3109/10253890.2015.1053451. Epub 2015 Jul 15. Review.

38.

Glucocorticoid signaling in the heart: A cardiomyocyte perspective.

Oakley RH, Cidlowski JA.

J Steroid Biochem Mol Biol. 2015 Sep;153:27-34. doi: 10.1016/j.jsbmb.2015.03.009. Epub 2015 Mar 21. Review.

39.

Adverse consequences of glucocorticoid medication: psychological, cognitive, and behavioral effects.

Judd LL, Schettler PJ, Brown ES, Wolkowitz OM, Sternberg EM, Bender BG, Bulloch K, Cidlowski JA, de Kloet ER, Fardet L, Joëls M, Leung DY, McEwen BS, Roozendaal B, Van Rossum EF, Ahn J, Brown DW, Plitt A, Singh G.

Am J Psychiatry. 2014 Oct;171(10):1045-51. doi: 10.1176/appi.ajp.2014.13091264. Erratum in: Am J Psychiatry. 2014 Nov 1;171(11):1224.

PMID:
25272344
40.

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015.

Galluzzi L, Bravo-San Pedro JM, Vitale I, Aaronson SA, Abrams JM, Adam D, Alnemri ES, Altucci L, Andrews D, Annicchiarico-Petruzzelli M, Baehrecke EH, Bazan NG, Bertrand MJ, Bianchi K, Blagosklonny MV, Blomgren K, Borner C, Bredesen DE, Brenner C, Campanella M, Candi E, Cecconi F, Chan FK, Chandel NS, Cheng EH, Chipuk JE, Cidlowski JA, Ciechanover A, Dawson TM, Dawson VL, De Laurenzi V, De Maria R, Debatin KM, Di Daniele N, Dixit VM, Dynlacht BD, El-Deiry WS, Fimia GM, Flavell RA, Fulda S, Garrido C, Gougeon ML, Green DR, Gronemeyer H, Hajnoczky G, Hardwick JM, Hengartner MO, Ichijo H, Joseph B, Jost PJ, Kaufmann T, Kepp O, Klionsky DJ, Knight RA, Kumar S, Lemasters JJ, Levine B, Linkermann A, Lipton SA, Lockshin RA, López-Otín C, Lugli E, Madeo F, Malorni W, Marine JC, Martin SJ, Martinou JC, Medema JP, Meier P, Melino S, Mizushima N, Moll U, Muñoz-Pinedo C, Nuñez G, Oberst A, Panaretakis T, Penninger JM, Peter ME, Piacentini M, Pinton P, Prehn JH, Puthalakath H, Rabinovich GA, Ravichandran KS, Rizzuto R, Rodrigues CM, Rubinsztein DC, Rudel T, Shi Y, Simon HU, Stockwell BR, Szabadkai G, Tait SW, Tang HL, Tavernarakis N, Tsujimoto Y, Vanden Berghe T, Vandenabeele P, Villunger A, Wagner EF, Walczak H, White E, Wood WG, Yuan J, Zakeri Z, Zhivotovsky B, Melino G, Kroemer G.

Cell Death Differ. 2015 Jan;22(1):58-73. doi: 10.1038/cdd.2014.137. Epub 2014 Sep 19. Review.

41.

One hormone, two actions: anti- and pro-inflammatory effects of glucocorticoids.

Cruz-Topete D, Cidlowski JA.

Neuroimmunomodulation. 2015;22(1-2):20-32. doi: 10.1159/000362724. Epub 2014 Sep 12. Review.

42.

Genistein disrupts glucocorticoid receptor signaling in human uterine endometrial Ishikawa cells.

Whirledge S, Senbanjo LT, Cidlowski JA.

Environ Health Perspect. 2015 Jan;123(1):80-7. doi: 10.1289/ehp.1408437. Epub 2014 Aug 19.

43.

International Union of Basic and Clinical Pharmacology. XC. multisite pharmacology: recommendations for the nomenclature of receptor allosterism and allosteric ligands.

Christopoulos A, Changeux JP, Catterall WA, Fabbro D, Burris TP, Cidlowski JA, Olsen RW, Peters JA, Neubig RR, Pin JP, Sexton PM, Kenakin TP, Ehlert FJ, Spedding M, Langmead CJ.

Pharmacol Rev. 2014 Oct;66(4):918-47. doi: 10.1124/pr.114.008862.

44.

Sexually dimorphic actions of glucocorticoids: beyond chromosomes and sex hormones.

Quinn M, Ramamoorthy S, Cidlowski JA.

Ann N Y Acad Sci. 2014 May;1317:1-6. doi: 10.1111/nyas.12425. Epub 2014 Apr 16. Review.

PMID:
24739020
45.

Ion channels and apoptosis in cancer.

Bortner CD, Cidlowski JA.

Philos Trans R Soc Lond B Biol Sci. 2014 Feb 3;369(1638):20130104. doi: 10.1098/rstb.2013.0104. Print 2014 Mar 19. Review.

46.

HES1 is a master regulator of glucocorticoid receptor-dependent gene expression.

Revollo JR, Oakley RH, Lu NZ, Kadmiel M, Gandhavadi M, Cidlowski JA.

Sci Signal. 2013 Dec 3;6(304):ra103. doi: 10.1126/scisignal.2004389.

47.

Deep sequencing identification of novel glucocorticoid-responsive miRNAs in apoptotic primary lymphocytes.

Smith LK, Tandon A, Shah RR, Mav D, Scoltock AB, Cidlowski JA.

PLoS One. 2013 Oct 24;8(10):e78316. doi: 10.1371/journal.pone.0078316. eCollection 2013.

48.

Analysis of glucocorticoid receptors and their apoptotic response to dexamethasone in male murine B cells during development.

Gruver-Yates AL, Quinn MA, Cidlowski JA.

Endocrinology. 2014 Feb;155(2):463-74. doi: 10.1210/en.2013-1473. Epub 2013 Nov 6.

49.

Glutathione depletion regulates both extrinsic and intrinsic apoptotic signaling cascades independent from multidrug resistance protein 1.

Franco R, Bortner CD, Schmitz I, Cidlowski JA.

Apoptosis. 2014 Jan;19(1):117-34. doi: 10.1007/s10495-013-0900-0.

50.

The biology of the glucocorticoid receptor: new signaling mechanisms in health and disease.

Oakley RH, Cidlowski JA.

J Allergy Clin Immunol. 2013 Nov;132(5):1033-44. doi: 10.1016/j.jaci.2013.09.007. Epub 2013 Sep 29. Review.

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