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Items: 1 to 50 of 131

1.

MAdCAM costimulation through Integrin-α4β7 promotes HIV replication.

Nawaz F, Goes LR, Ray JC, Olowojesiku R, Sajani A, Ansari AA, Perrone I, Hiatt J, Van Ryk D, Wei D, Waliszewski M, Soares MA, Jelicic K, Connors M, Migueles SA, Martinelli E, Villinger F, Cicala C, Fauci AS, Arthos J.

Mucosal Immunol. 2018 Jun 6. doi: 10.1038/s41385-018-0044-1. [Epub ahead of print]

PMID:
29875402
2.

The Role of Integrin α4β7 in HIV Pathogenesis and Treatment.

Arthos J, Cicala C, Nawaz F, Byrareddy SN, Villinger F, Santangelo PJ, Ansari AA, Fauci AS.

Curr HIV/AIDS Rep. 2018 Apr;15(2):127-135. doi: 10.1007/s11904-018-0382-3. Review.

3.

Signal peptide of HIV envelope protein impacts glycosylation and antigenicity of gp120.

Yolitz J, Schwing C, Chang J, Van Ryk D, Nawaz F, Wei D, Cicala C, Arthos J, Fauci AS.

Proc Natl Acad Sci U S A. 2018 Mar 6;115(10):2443-2448. doi: 10.1073/pnas.1722627115. Epub 2018 Feb 20.

4.

Integrin α4β7 expression on peripheral blood CD4+ T cells predicts HIV acquisition and disease progression outcomes.

Sivro A, Schuetz A, Sheward D, Joag V, Yegorov S, Liebenberg LJ, Yende-Zuma N, Stalker A, Mwatelah RS, Selhorst P, Garrett N, Samsunder N, Balgobin A, Nawaz F, Cicala C, Arthos J, Fauci AS, Anzala AO, Kimani J, Bagaya BS, Kiwanuka N, Williamson C, Kaul R, Passmore JS, Phanuphak N, Ananworanich J, Ansari A, Abdool Karim Q, Abdool Karim SS, McKinnon LR; CAPRISA004 and RV254 study groups.

Sci Transl Med. 2018 Jan 24;10(425). pii: eaam6354. doi: 10.1126/scitranslmed.aam6354.

PMID:
29367348
5.

Early treatment of SIV+ macaques with an α4β7 mAb alters virus distribution and preserves CD4+ T cells in later stages of infection.

Santangelo PJ, Cicala C, Byrareddy SN, Ortiz KT, Little D, Lindsay KE, Gumber S, Hong JJ, Jelicic K, Rogers KA, Zurla C, Villinger F, Ansari AA, Fauci AS, Arthos J.

Mucosal Immunol. 2018 May;11(3):932-946. doi: 10.1038/mi.2017.112. Epub 2017 Dec 20.

6.

Palmitoylethanolamide Supplementation during Sensitization Prevents Airway Allergic Symptoms in the Mouse.

Roviezzo F, Rossi A, Caiazzo E, Orlando P, Riemma MA, Iacono VM, Guarino A, Ialenti A, Cicala C, Peritore A, Capasso R, Di Marzo V, Izzo AA.

Front Pharmacol. 2017 Dec 12;8:857. doi: 10.3389/fphar.2017.00857. eCollection 2017.

7.
8.

Integrin α4β7 Blockade Preferentially Impacts CCR6+ Lymphocyte Subsets in Blood and Mucosal Tissues of Naive Rhesus Macaques.

Calenda G, Keawvichit R, Arrode-Brusés G, Pattanapanyasat K, Frank I, Byrareddy SN, Arthos J, Cicala C, Grasperge B, Blanchard JL, Gettie A, Reimann KA, Ansari AA, Martinelli E.

J Immunol. 2018 Jan 15;200(2):810-820. doi: 10.4049/jimmunol.1701150. Epub 2017 Dec 1.

PMID:
29196458
9.

Correction: Rare HIV-1 transmitted/founder lineages identified by deep viral sequencing contribute to rapid shifts in dominant quasispecies during acute and early infection.

Kijak GH, Sanders-Buell E, Chenine AL, Eller MA, Goonetilleke N, Thomas R, Leviyang S, Harbolick EA, Bose M, Pham P, Oropeza C, Poltavee K, O'Sullivan AM, Billings E, Merbah M, Costanzo MC, Warren JA, Slike B, Li H, Peachman KK, Fischer W, Gao F, Cicala C, Arthos J, Eller LA, O'Connell RJ, Sinei S, Maganga L, Kibuuka H, Nitayaphan S, Rao M, Marovich MA, Krebs SJ, Rolland M, Korber BT, Shaw GM, Michael NL, Robb ML, Tovanabutra S, Kim JH.

PLoS Pathog. 2017 Sep 14;13(9):e1006620. doi: 10.1371/journal.ppat.1006620. eCollection 2017 Sep.

10.

Virion incorporation of integrin α4β7 facilitates HIV-1 infection and intestinal homing.

Guzzo C, Ichikawa D, Park C, Phillips D, Liu Q, Zhang P, Kwon A, Miao H, Lu J, Rehm C, Arthos J, Cicala C, Cohen MS, Fauci AS, Kehrl JH, Lusso P.

Sci Immunol. 2017 May 12;2(11). pii: eaam7341. doi: 10.1126/sciimmunol.aam7341.

11.

Rare HIV-1 transmitted/founder lineages identified by deep viral sequencing contribute to rapid shifts in dominant quasispecies during acute and early infection.

Kijak GH, Sanders-Buell E, Chenine AL, Eller MA, Goonetilleke N, Thomas R, Leviyang S, Harbolick EA, Bose M, Pham P, Oropeza C, Poltavee K, O'Sullivan AM, Billings E, Merbah M, Costanzo MC, Warren JA, Slike B, Li H, Peachman KK, Fischer W, Gao F, Cicala C, Arthos J, Eller LA, O'Connell RJ, Sinei S, Maganga L, Kibuuka H, Nitayaphan S, Rao M, Marovich MA, Krebs SJ, Rolland M, Korber BT, Shaw GM, Michael NL, Robb ML, Tovanabutra S, Kim JH.

PLoS Pathog. 2017 Jul 31;13(7):e1006510. doi: 10.1371/journal.ppat.1006510. eCollection 2017 Jul. Erratum in: PLoS Pathog. 2017 Sep 14;13(9):e1006620.

12.

Neutralizing and Targeting Properties of a New Set of α4β7-Specific Antibodies Are Influenced by Their Isotype.

Girard A, Jelicic K, Van Ryk D, Rochereau N, Cicala C, Arthos J, Noailly B, Genin C, Verrier B, Laurant S, Razanajaoana-Doll D, Pin JJ, Paul S.

J Acquir Immune Defic Syndr. 2017 May 1;75(1):118-127. doi: 10.1097/QAI.0000000000001307.

PMID:
28177967
13.

Salvinorin A Inhibits Airway Hyperreactivity Induced by Ovalbumin Sensitization.

Rossi A, Caiazzo E, Bilancia R, Riemma MA, Pagano E, Cicala C, Ialenti A, Zjawiony JK, Izzo AA, Capasso R, Roviezzo F.

Front Pharmacol. 2017 Jan 13;7:525. doi: 10.3389/fphar.2016.00525. eCollection 2016.

14.

Sustained virologic control in SIV+ macaques after antiretroviral and α4β7 antibody therapy.

Byrareddy SN, Arthos J, Cicala C, Villinger F, Ortiz KT, Little D, Sidell N, Kane MA, Yu J, Jones JW, Santangelo PJ, Zurla C, McKinnon LR, Arnold KB, Woody CE, Walter L, Roos C, Noll A, Van Ryk D, Jelicic K, Cimbro R, Gumber S, Reid MD, Adsay V, Amancha PK, Mayne AE, Parslow TG, Fauci AS, Ansari AA.

Science. 2016 Oct 14;354(6309):197-202.

15.

HIV Envelope gp120 Alters T Cell Receptor Mobilization in the Immunological Synapse of Uninfected CD4 T Cells and Augments T Cell Activation.

Deng J, Mitsuki YY, Shen G, Ray JC, Cicala C, Arthos J, Dustin ML, Hioe CE.

J Virol. 2016 Nov 14;90(23):10513-10526. Print 2016 Dec 1.

16.

Red Wine Inhibits Aggregation and Increases ATP-diphosphohydrolase (CD39) Activity of Rat Platelets in Vitro.

Caiazzo E, Tedesco I, Spagnuolo C, Russo GL, Ialenti A, Cicala C.

Nat Prod Commun. 2016 Jun;11(6):771-4.

PMID:
27534113
17.

Adenosine signalling mediates the anti-inflammatory effects of the COX-2 inhibitor nimesulide.

Caiazzo E, Maione F, Morello S, Lapucci A, Paccosi S, Steckel B, Lavecchia A, Parenti A, Iuvone T, Schrader J, Ialenti A, Cicala C.

Biochem Pharmacol. 2016 Jul 15;112:72-81. doi: 10.1016/j.bcp.2016.05.006. Epub 2016 May 14.

PMID:
27188793
18.

Impairment of T cell development and acute inflammatory response in HIV-1 Tat transgenic mice.

Fiume G, Scialdone A, Albano F, Rossi A, Tuccillo FM, Rea D, Palmieri C, Caiazzo E, Cicala C, Bellevicine C, Falcone C, Vecchio E, Pisano A, Ceglia S, Mimmi S, Iaccino E, de Laurentiis A, Pontoriero M, Agosti V, Troncone G, Mignogna C, Palma G, Arra C, Mallardo M, Buonaguro FM, Scala G, Quinto I.

Sci Rep. 2015 Sep 7;5:13864. doi: 10.1038/srep13864.

19.

HIV-1 gp120: A Target for Therapeutics and Vaccine Design.

Cicala C, Nawaz F, Jelicic K, Arthos J, Fauci AS.

Curr Drug Targets. 2016;17(1):122-35. Review.

PMID:
26302793
20.
21.

Species-specific differences in the expression and regulation of α4β7 integrin in various nonhuman primates.

Byrareddy SN, Sidell N, Arthos J, Cicala C, Zhao C, Little DM, Dunbar P, Yang GX, Pierzchalski K, Kane MA, Mayne AE, Song B, Soares MA, Villinger F, Fauci AS, Ansari AA.

J Immunol. 2015 Jun 15;194(12):5968-79. doi: 10.4049/jimmunol.1402866. Epub 2015 May 6.

22.

Neutrophil recruitment to lymph nodes limits local humoral response to Staphylococcus aureus.

Kamenyeva O, Boularan C, Kabat J, Cheung GY, Cicala C, Yeh AJ, Chan JL, Periasamy S, Otto M, Kehrl JH.

PLoS Pathog. 2015 Apr 17;11(4):e1004827. doi: 10.1371/journal.ppat.1004827. eCollection 2015 Apr.

23.

Targeting α4β7 integrin reduces mucosal transmission of simian immunodeficiency virus and protects gut-associated lymphoid tissue from infection.

Byrareddy SN, Kallam B, Arthos J, Cicala C, Nawaz F, Hiatt J, Kersh EN, McNicholl JM, Hanson D, Reimann KA, Brameier M, Walter L, Rogers K, Mayne AE, Dunbar P, Villinger T, Little D, Parslow TG, Santangelo PJ, Villinger F, Fauci AS, Ansari AA.

Nat Med. 2014 Dec;20(12):1397-400. doi: 10.1038/nm.3715. Epub 2014 Nov 24.

24.

Tanshinone IIA, a major component of Salvia milthorriza Bunge, inhibits platelet activation via Erk-2 signaling pathway.

Maione F, De Feo V, Caiazzo E, De Martino L, Cicala C, Mascolo N.

J Ethnopharmacol. 2014 Sep 11;155(2):1236-42. doi: 10.1016/j.jep.2014.07.010. Epub 2014 Jul 16.

PMID:
25038434
25.

Interleukin-17A Exacerbates Ferric Chloride-Induced Arterial Thrombosis in Rat Carotid Artery.

Maione F, Parisi A, Caiazzo E, Morello S, D'Acquisto F, Mascolo N, Cicala C.

Int J Inflam. 2014;2014:247503. doi: 10.1155/2014/247503. Epub 2014 Apr 3.

26.

The HIV-1 envelope protein gp120 impairs B cell proliferation by inducing TGF-β1 production and FcRL4 expression.

Jelicic K, Cimbro R, Nawaz F, Huang da W, Zheng X, Yang J, Lempicki RA, Pascuccio M, Van Ryk D, Schwing C, Hiatt J, Okwara N, Wei D, Roby G, David A, Hwang IY, Kehrl JH, Arthos J, Cicala C, Fauci AS.

Nat Immunol. 2013 Dec;14(12):1256-65. doi: 10.1038/ni.2746. Epub 2013 Oct 27.

27.

Virion attachment and entry: HIV gp120 Env biotinylation, gp120 Env, or integrin ligand-binding assay.

Cicala C, Arthos J.

Methods Mol Biol. 2014;1087:3-12. doi: 10.1007/978-1-62703-670-2_1.

PMID:
24158809
28.

Adenosine signaling in airways: toward a promising antiasthmatic approach.

Cicala C, Ialenti A.

Eur J Pharmacol. 2013 Aug 15;714(1-3):522-5. doi: 10.1016/j.ejphar.2013.06.033. Epub 2013 Jul 11.

PMID:
23850943
29.

Phenols, alkaloids and terpenes from medicinal plants with antihypertensive and vasorelaxant activities. A review of natural products as leads to potential therapeutic agents.

Maione F, Cicala C, Musciacco G, De Feo V, Amat AG, Ialenti A, Mascolo N.

Nat Prod Commun. 2013 Apr;8(4):539-44. Review.

PMID:
23738474
30.

[Classifications of urinary diversions].

Cicala C.

Urologia. 2012 Dec 30;79 Suppl 19:20-3. doi: 10.5301/RU.2012.9741. Italian.

PMID:
23371267
31.

Bombesin peptide antagonist for target-selective delivery of liposomal doxorubicin on cancer cells.

Accardo A, Mansi R, Salzano G, Morisco A, Aurilio M, Parisi A, Maione F, Cicala C, Ziaco B, Tesauro D, Aloj L, De Rosa G, Morelli G.

J Drug Target. 2012 Nov 21. [Epub ahead of print]

PMID:
23167653
32.

Bindarit inhibits human coronary artery smooth muscle cell proliferation, migration and phenotypic switching.

Maddaluno M, Grassia G, Di Lauro MV, Parisi A, Maione F, Cicala C, De Filippis D, Iuvone T, Guglielmotti A, Maffia P, Mascolo N, Ialenti A.

PLoS One. 2012;7(10):e47464. doi: 10.1371/journal.pone.0047464. Epub 2012 Oct 15.

33.

Hyperresponsiveness to adenosine in sensitized Wistar rats over-expressing A1 receptor.

Alfieri A, Parisi A, Maione F, Grassia G, Morello S, Ialenti A, Mascolo N, Cicala C.

Eur J Pharmacol. 2012 Nov 15;695(1-3):120-5. doi: 10.1016/j.ejphar.2012.09.002. Epub 2012 Sep 19.

PMID:
23000391
34.

IL-7 induces expression and activation of integrin α4β7 promoting naive T-cell homing to the intestinal mucosa.

Cimbro R, Vassena L, Arthos J, Cicala C, Kehrl JH, Park C, Sereti I, Lederman MM, Fauci AS, Lusso P.

Blood. 2012 Sep 27;120(13):2610-9. Epub 2012 Aug 14.

35.

Inhibition of CD73 improves B cell-mediated anti-tumor immunity in a mouse model of melanoma.

Forte G, Sorrentino R, Montinaro A, Luciano A, Adcock IM, Maiolino P, Arra C, Cicala C, Pinto A, Morello S.

J Immunol. 2012 Sep 1;189(5):2226-33. doi: 10.4049/jimmunol.1200744. Epub 2012 Jul 23.

36.

Peptide-modified liposomes for selective targeting of bombesin receptors overexpressed by cancer cells: a potential theranostic agent.

Accardo A, Salsano G, Morisco A, Aurilio M, Parisi A, Maione F, Cicala C, Tesauro D, Aloj L, De Rosa G, Morelli G.

Int J Nanomedicine. 2012;7:2007-17. doi: 10.2147/IJN.S29242. Epub 2012 Apr 17.

37.

Diuretic activity of Lophophytum leandri.

Bracci A, Amat AG, Maione F, Cicala C, Mascolo N, De Feo V.

Nat Prod Commun. 2012 Jan;7(1):33-4.

PMID:
22428237
38.

Characterization of a human cervical CD4+ T cell subset coexpressing multiple markers of HIV susceptibility.

McKinnon LR, Nyanga B, Chege D, Izulla P, Kimani M, Huibner S, Gelmon L, Block KE, Cicala C, Anzala AO, Arthos J, Kimani J, Kaul R.

J Immunol. 2011 Dec 1;187(11):6032-42. doi: 10.4049/jimmunol.1101836. Epub 2011 Nov 2.

39.

Siglecs facilitate HIV-1 infection of macrophages through adhesion with viral sialic acids.

Zou Z, Chastain A, Moir S, Ford J, Trandem K, Martinelli E, Cicala C, Crocker P, Arthos J, Sun PD.

PLoS One. 2011;6(9):e24559. doi: 10.1371/journal.pone.0024559. Epub 2011 Sep 8.

40.

Biological activity of bicyclic and tricyclic diterpenoids from Salvia species of immediate pharmacological and pharmaceutical interest.

Bonito MC, Cicala C, Marcotullio MC, Maione F, Mascolo N.

Nat Prod Commun. 2011 Aug;6(8):1205-15.

PMID:
21922935
41.

Polymorphisms in the α4 integrin of neotropical primates: insights for binding of natural ligands and HIV-1 gp120 to the human α4β7.

Darc M, Hait SH, Soares EA, Cicala C, Seuanez HN, Machado ES, Arthos JA, Soares MA.

PLoS One. 2011;6(9):e24461. doi: 10.1371/journal.pone.0024461. Epub 2011 Sep 2.

42.

IL-17A increases ADP-induced platelet aggregation.

Maione F, Cicala C, Liverani E, Mascolo N, Perretti M, D'Acquisto F.

Biochem Biophys Res Commun. 2011 May 20;408(4):658-62. doi: 10.1016/j.bbrc.2011.04.080. Epub 2011 Apr 22.

43.

The genotype of early-transmitting HIV gp120s promotes α (4) β(7)-reactivity, revealing α (4) β(7) +/CD4+ T cells as key targets in mucosal transmission.

Nawaz F, Cicala C, Van Ryk D, Block KE, Jelicic K, McNally JP, Ogundare O, Pascuccio M, Patel N, Wei D, Fauci AS, Arthos J.

PLoS Pathog. 2011 Feb;7(2):e1001301. doi: 10.1371/journal.ppat.1001301. Epub 2011 Feb 24.

44.

HIV-1 envelope, integrins and co-receptor use in mucosal transmission of HIV.

Cicala C, Arthos J, Fauci AS.

J Transl Med. 2011 Jan 27;9 Suppl 1:S2. doi: 10.1186/1479-5876-9-S1-S2. Review.

45.

The integrin alpha4beta7 forms a complex with cell-surface CD4 and defines a T-cell subset that is highly susceptible to infection by HIV-1.

Cicala C, Martinelli E, McNally JP, Goode DJ, Gopaul R, Hiatt J, Jelicic K, Kottilil S, Macleod K, O'Shea A, Patel N, Van Ryk D, Wei D, Pascuccio M, Yi L, McKinnon L, Izulla P, Kimani J, Kaul R, Fauci AS, Arthos J.

Proc Natl Acad Sci U S A. 2009 Dec 8;106(49):20877-82. doi: 10.1073/pnas.0911796106. Epub 2009 Nov 20.

46.

Protective effect of dimethyl sulfoxide on acute myocardial infarction in rats.

Parisi A, Alfieri A, Mazzella M, Mazzella A, Scognamiglio M, Scognamiglio G, Mascolo N, Cicala C.

J Cardiovasc Pharmacol. 2010 Jan;55(1):106-9. doi: 10.1097/FJC.0b013e3181c87a65.

PMID:
19904216
47.

First evidence for an anxiolytic effect of a diterpenoid from Salvia cinnabarina.

Maione F, Bonito MC, Colucci M, Cozzolino V, Bisio A, Romussi G, Cicala C, Pieretti S, Mascolo N.

Nat Prod Commun. 2009 Apr;4(4):469-72.

PMID:
19475986
48.

D-dimers are not always elevated in patients with acute aortic dissection.

Paparella D, Malvindi PG, Scrascia G, de Ceglia D, Rotunno C, Tunzi F, Cicala C, de Luca Tupputi Schinosa L.

J Cardiovasc Med (Hagerstown). 2009 Feb;10(2):212-4. doi: 10.2459/JCM.0b013e32831c849e.

PMID:
19377387
49.

HIV-1 envelope protein binds to and signals through integrin alpha4beta7, the gut mucosal homing receptor for peripheral T cells.

Arthos J, Cicala C, Martinelli E, Macleod K, Van Ryk D, Wei D, Xiao Z, Veenstra TD, Conrad TP, Lempicki RA, McLaughlin S, Pascuccio M, Gopaul R, McNally J, Cruz CC, Censoplano N, Chung E, Reitano KN, Kottilil S, Goode DJ, Fauci AS.

Nat Immunol. 2008 Mar;9(3):301-9. doi: 10.1038/ni1566. Epub 2008 Feb 10.

PMID:
18264102
50.

Structural basis for the interaction between focal adhesion kinase and CD4.

Garron ML, Arthos J, Guichou JF, McNally J, Cicala C, Arold ST.

J Mol Biol. 2008 Feb 1;375(5):1320-8. Epub 2007 Nov 22.

PMID:
18078954

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