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Items: 20

1.

Methods to Investigate β-Arrestin-1/β-Catenin Signaling in Ovarian Cancer Cells.

Rosanò L, Cianfrocca R, Bagnato A.

Methods Mol Biol. 2019;1957:393-406. doi: 10.1007/978-1-4939-9158-7_25.

PMID:
30919368
2.

Targeting endothelin-1 receptor/β-arrestin1 network for the treatment of ovarian cancer.

Rosanò L, Cianfrocca R, Sestito R, Tocci P, Di Castro V, Bagnato A.

Expert Opin Ther Targets. 2017 Oct;21(10):925-932. doi: 10.1080/14728222.2017.1361930. Epub 2017 Sep 5. Review.

PMID:
28758529
3.

Blocking endothelin-1-receptor/β-catenin circuit sensitizes to chemotherapy in colorectal cancer.

Cianfrocca R, Rosanò L, Tocci P, Sestito R, Caprara V, Di Castro V, De Maria R, Bagnato A.

Cell Death Differ. 2017 Oct;24(10):1811-1820. doi: 10.1038/cdd.2017.121. Epub 2017 Jul 14.

4.

Nuclear β-arrestin1 is a critical cofactor of hypoxia-inducible factor-1α signaling in endothelin-1-induced ovarian tumor progression.

Cianfrocca R, Tocci P, Rosanò L, Caprara V, Sestito R, Di Castro V, Bagnato A.

Oncotarget. 2016 Apr 5;7(14):17790-804. doi: 10.18632/oncotarget.7461.

5.

Endothelin-1/endothelin A receptor axis activates RhoA GTPase in epithelial ovarian cancer.

Tocci P, Caprara V, Cianfrocca R, Sestito R, Di Castro V, Bagnato A, Rosanò L.

Life Sci. 2016 Aug 15;159:49-54. doi: 10.1016/j.lfs.2016.01.008. Epub 2016 Jan 8.

PMID:
26776837
6.

Macitentan blocks endothelin-1 receptor activation required for chemoresistant ovarian cancer cell plasticity and metastasis.

Sestito R, Cianfrocca R, Rosanò L, Tocci P, Di Castro V, Caprara V, Bagnato A.

Life Sci. 2016 Aug 15;159:43-48. doi: 10.1016/j.lfs.2016.01.009. Epub 2016 Jan 8.

PMID:
26776834
7.

miR-30a inhibits endothelin A receptor and chemoresistance in ovarian carcinoma.

Sestito R, Cianfrocca R, Rosanò L, Tocci P, Semprucci E, Di Castro V, Caprara V, Ferrandina G, Sacconi A, Blandino G, Bagnato A.

Oncotarget. 2016 Jan 26;7(4):4009-23. doi: 10.18632/oncotarget.6546.

8.

Endothelin A receptor drives invadopodia function and cell motility through the β-arrestin/PDZ-RhoGEF pathway in ovarian carcinoma.

Semprucci E, Tocci P, Cianfrocca R, Sestito R, Caprara V, Veglione M, Castro VD, Spadaro F, Ferrandina G, Bagnato A, Rosanò L.

Oncogene. 2016 Jun 30;35(26):3432-42. doi: 10.1038/onc.2015.403. Epub 2015 Nov 2.

PMID:
26522724
9.

Endothelin A receptor/β-arrestin signaling to the Wnt pathway renders ovarian cancer cells resistant to chemotherapy.

Rosanò L, Cianfrocca R, Tocci P, Spinella F, Di Castro V, Caprara V, Semprucci E, Ferrandina G, Natali PG, Bagnato A.

Cancer Res. 2014 Dec 15;74(24):7453-64. doi: 10.1158/0008-5472.CAN-13-3133. Epub 2014 Nov 6.

10.

β-Arrestin 1 is required for endothelin-1-induced NF-κB activation in ovarian cancer cells.

Cianfrocca R, Tocci P, Semprucci E, Spinella F, Di Castro V, Bagnato A, Rosanò L.

Life Sci. 2014 Nov 24;118(2):179-84. doi: 10.1016/j.lfs.2014.01.078. Epub 2014 Feb 12.

11.

The interplay between hypoxia, endothelial and melanoma cells regulates vascularization and cell motility through endothelin-1 and vascular endothelial growth factor.

Spinella F, Caprara V, Cianfrocca R, Rosanò L, Di Castro V, Garrafa E, Natali PG, Bagnato A.

Carcinogenesis. 2014 Apr;35(4):840-8. doi: 10.1093/carcin/bgu018. Epub 2014 Jan 28.

12.

β-arrestin-1 is a nuclear transcriptional regulator of endothelin-1-induced β-catenin signaling.

Rosanò L, Cianfrocca R, Tocci P, Spinella F, Di Castro V, Spadaro F, Salvati E, Biroccio AM, Natali PG, Bagnato A.

Oncogene. 2013 Oct 17;32(42):5066-77. doi: 10.1038/onc.2012.527. Epub 2012 Dec 3.

PMID:
23208497
13.

Endothelin-1 induces the transactivation of vascular endothelial growth factor receptor-3 and modulates cell migration and vasculogenic mimicry in melanoma cells.

Spinella F, Caprara V, Di Castro V, Rosanò L, Cianfrocca R, Natali PG, Bagnato A.

J Mol Med (Berl). 2013 Mar;91(3):395-405. doi: 10.1007/s00109-012-0956-2. Epub 2012 Sep 11.

PMID:
22965194
14.

The endothelin A receptor and epidermal growth factor receptor signaling converge on β-catenin to promote ovarian cancer metastasis.

Cianfrocca R, Tocci P, Spinella F, Di Castro V, Bagnato A, Rosanò L.

Life Sci. 2012 Oct 15;91(13-14):550-6. doi: 10.1016/j.lfs.2012.03.023. Epub 2012 Mar 28.

15.

Acquisition of chemoresistance and EMT phenotype is linked with activation of the endothelin A receptor pathway in ovarian carcinoma cells.

Rosanò L, Cianfrocca R, Spinella F, Di Castro V, Nicotra MR, Lucidi A, Ferrandina G, Natali PG, Bagnato A.

Clin Cancer Res. 2011 Apr 15;17(8):2350-60. doi: 10.1158/1078-0432.CCR-10-2325. Epub 2011 Jan 10.

16.

Beta-arrestin-1 mediates the endothelin-1-induced activation of Akt and integrin-linked kinase.

Cianfrocca R, Rosanò L, Spinella F, Di Castro V, Natali PG, Bagnato A.

Can J Physiol Pharmacol. 2010 Aug;88(8):796-801. doi: 10.1139/Y10-052.

17.

Combination therapy of zibotentan with cisplatinum and paclitaxel is an effective regimen for epithelial ovarian cancer.

Rosanò L, Cianfrocca R, Spinella F, Di Castro V, Natali PG, Bagnato A.

Can J Physiol Pharmacol. 2010 Jun;88(6):676-81. doi: 10.1139/Y10-053.

18.

Beta-arrestin links endothelin A receptor to beta-catenin signaling to induce ovarian cancer cell invasion and metastasis.

Rosanò L, Cianfrocca R, Masi S, Spinella F, Di Castro V, Biroccio A, Salvati E, Nicotra MR, Natali PG, Bagnato A.

Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2806-11. doi: 10.1073/pnas.0807158106. Epub 2009 Feb 6.

19.

Trichostatin A up-regulates p73 and induces Bax-dependent apoptosis in cisplatin-resistant ovarian cancer cells.

Muscolini M, Cianfrocca R, Sajeva A, Mozzetti S, Ferrandina G, Costanzo A, Tuosto L.

Mol Cancer Ther. 2008 Jun;7(6):1410-9. doi: 10.1158/1535-7163.MCT-08-0299.

20.

RelA/NF-kappaB recruitment on the bax gene promoter antagonizes p73-dependent apoptosis in costimulated T cells.

Cianfrocca R, Muscolini M, Marzano V, Annibaldi A, Marinari B, Levrero M, Costanzo A, Tuosto L.

Cell Death Differ. 2008 Feb;15(2):354-63. Epub 2007 Nov 23.

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