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Items: 23

1.

Differential cytotoxicity responses by dog and rat hepatocytes to phospholipogenic treatments.

Morelli JK, Ciaccio PJ.

J Toxicol. 2013;2013:956404. doi: 10.1155/2013/956404. Epub 2013 Mar 13.

2.

Phospholipogenic pharmaceuticals are associated with a higher incidence of histological findings than nonphospholipogenic pharmaceuticals in preclinical toxicology studies.

Barone LR, Boyer S, Damewood JR Jr, Fikes J, Ciaccio PJ.

J Toxicol. 2012;2012:308594. doi: 10.1155/2012/308594. Epub 2012 Jun 14.

3.

2,6-Disubstituted pyrazines and related analogs as NR2B site antagonists of the NMDA receptor with anti-depressant activity.

Brown DG, Maier DL, Sylvester MA, Hoerter TN, Menhaji-Klotz E, Lasota CC, Hirata LT, Wilkins DE, Scott CW, Trivedi S, Chen T, McCarthy DJ, Maciag CM, Sutton EJ, Cumberledge J, Mathisen D, Roberts J, Gupta A, Liu F, Elmore CS, Alhambra C, Krumrine JR, Wang X, Ciaccio PJ, Wood MW, Campbell JB, Johansson MJ, Xia J, Wen X, Jiang J, Wang X, Peng Z, Hu T, Wang J.

Bioorg Med Chem Lett. 2011 Jun 1;21(11):3399-403. doi: 10.1016/j.bmcl.2011.03.117. Epub 2011 Apr 8.

PMID:
21524576
4.

Validation of an in vitro screen for phospholipidosis using a high-content biology platform.

Morelli JK, Buehrle M, Pognan F, Barone LR, Fieles W, Ciaccio PJ.

Cell Biol Toxicol. 2006 Jan;22(1):15-27.

PMID:
16463016
5.

Modulation of notch processing by gamma-secretase inhibitors causes intestinal goblet cell metaplasia and induction of genes known to specify gut secretory lineage differentiation.

Milano J, McKay J, Dagenais C, Foster-Brown L, Pognan F, Gadient R, Jacobs RT, Zacco A, Greenberg B, Ciaccio PJ.

Toxicol Sci. 2004 Nov;82(1):341-58. Epub 2004 Aug 19.

PMID:
15319485
6.

Genomic sequence of human glyoxalase-I: analysis of promoter activity and its regulation.

Ranganathan S, Ciaccio PJ, Walsh ES, Tew KD.

Gene. 1999 Nov 15;240(1):149-55.

PMID:
10564821
7.

Investigation of the positive response of ethyl acrylate in the mouse lymphoma genotoxicity assay.

Ciaccio PJ, Gicquel E, O'Neill PJ, Scribner HE, Vandenberghe YL.

Toxicol Sci. 1998 Dec;46(2):324-32.

PMID:
10048136
8.

Promoter analysis of a human dihydrodiol dehydrogenase.

Ciaccio PJ, Walsh ES, Tew KD.

Biochem Biophys Res Commun. 1996 Nov 12;228(2):524-9.

PMID:
8920946
9.

Adaptive response to glutathione S-transferase inhibitors.

Ciaccio PJ, Tew KD.

Br J Cancer Suppl. 1996 Jul;27:S93-8. Review. No abstract available.

10.

Cellular and in vitro transport of glutathione conjugates by MRP.

Shen H, Paul S, Breuninger LM, Ciaccio PJ, Laing NM, Helt M, Tew KD, Kruh GD.

Biochemistry. 1996 May 7;35(18):5719-25. Retraction in: Biochemistry. 1997 Nov 11;36(45):13972.

PMID:
8639531
11.

Effects of chronic ethacrynic acid exposure on glutathione conjugation and MRP expression in human colon tumor cells.

Ciaccio PJ, Shen H, Kruh GD, Tew KD.

Biochem Biophys Res Commun. 1996 May 6;222(1):111-5.

PMID:
8630053
12.

Isozyme-specific glutathione S-transferase inhibitors potentiate drug sensitivity in cultured human tumor cell lines.

Morgan AS, Ciaccio PJ, Tew KD, Kauvar LM.

Cancer Chemother Pharmacol. 1996;37(4):363-70.

PMID:
8548883
13.

Modulation of detoxification gene expression in human colon HT29 cells by glutathione-S-transferase inhibitors.

Ciaccio PJ, Shen H, Jaiswal AK, Lyttle MH, Tew KD.

Mol Pharmacol. 1995 Oct;48(4):639-47.

PMID:
7476889
14.

cDNA and deduced amino acid sequences of a human colon dihydrodiol dehydrogenase.

Ciaccio PJ, Tew KD.

Biochim Biophys Acta. 1994 Jun 28;1186(1-2):129-32.

PMID:
8011662
15.

Regulation of human dihydrodiol dehydrogenase by Michael acceptor xenobiotics.

Ciaccio PJ, Jaiswal AK, Tew KD.

J Biol Chem. 1994 Jun 3;269(22):15558-62.

17.

Enzymatic conjugation of chlorambucil with glutathione by human glutathione S-transferases and inhibition by ethacrynic acid.

Ciaccio PJ, Tew KD, LaCreta FP.

Biochem Pharmacol. 1991 Sep 12;42(7):1504-7. No abstract available.

PMID:
1930278
18.

cDNA and deduced amino acid sequences of a dog liver cytochrome P-450 of the IIIA gene subfamily.

Ciaccio PJ, Graves PE, Bourque DP, Glinsmann-Gibson B, Halpert JR.

Biochim Biophys Acta. 1991 Feb 16;1088(2):319-22.

PMID:
2001406
19.

cDNA and deduced amino acid sequences of a dog hepatic cytochrome P450IIB responsible for the metabolism of 2,2',4,4',5,5'-hexachlorobiphenyl.

Graves PE, Elhag GA, Ciaccio PJ, Bourque DP, Halpert JR.

Arch Biochem Biophys. 1990 Aug 15;281(1):106-15.

PMID:
2116765
20.

The spontaneous and glutathione S-transferase-mediated reaction of chlorambucil with glutathione.

Ciaccio PJ, Tew KD, LaCreta FP.

Cancer Commun. 1990;2(8):279-85. Erratum in: Cancer Commun 1990;2(9):325.

PMID:
2390420
22.

The metabolism of xenobiotics and endogenous compounds by the constitutive dog liver cytochrome P450 PBD-2.

Duignan DB, Sipes IG, Ciaccio PJ, Halpert JR.

Arch Biochem Biophys. 1988 Nov 15;267(1):294-304.

PMID:
3143308
23.

Selective inactivation by chloramphenicol of the major phenobarbital-inducible isozyme of dog liver cytochrome P-450.

Ciaccio PJ, Duignan DB, Halpert JR.

Drug Metab Dispos. 1987 Nov-Dec;15(6):852-6.

PMID:
2893713

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