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Items: 18

1.

The effects of licogliflozin, a dual SGLT1/2 inhibitor, on body weight in obese patients with or without diabetes.

He YL, Haynes W, Meyers CD, Amer A, Zhang Y, Mahling P, Mendonza AE, Ma S, Chutkow W, Bachman E.

Diabetes Obes Metab. 2019 Jun;21(6):1311-1321. doi: 10.1111/dom.13654. Epub 2019 Mar 15.

PMID:
30724002
2.

Thioredoxin-interacting protein regulates protein disulfide isomerases and endoplasmic reticulum stress.

Lee S, Min Kim S, Dotimas J, Li L, Feener EP, Baldus S, Myers RB, Chutkow WA, Patwari P, Yoshioka J, Lee RT.

EMBO Mol Med. 2014 Jun;6(6):732-43. doi: 10.15252/emmm.201302561. Epub 2014 Apr 6.

3.

Myocardial infarction triggers chronic cardiac autoimmunity in type 1 diabetes.

Gottumukkala RV, Lv H, Cornivelli L, Wagers AJ, Kwong RY, Bronson R, Stewart GC, Schulze PC, Chutkow W, Wolpert HA, Lee RT, Lipes MA.

Sci Transl Med. 2012 Jun 13;4(138):138ra80. doi: 10.1126/scitranslmed.3003551.

4.

Deletion of thioredoxin-interacting protein in mice impairs mitochondrial function but protects the myocardium from ischemia-reperfusion injury.

Yoshioka J, Chutkow WA, Lee S, Kim JB, Yan J, Tian R, Lindsey ML, Feener EP, Seidman CE, Seidman JG, Lee RT.

J Clin Invest. 2012 Jan;122(1):267-79. doi: 10.1172/JCI44927. Epub 2011 Dec 27.

5.

The arrestin domain-containing 3 protein regulates body mass and energy expenditure.

Patwari P, Emilsson V, Schadt EE, Chutkow WA, Lee S, Marsili A, Zhang Y, Dobrin R, Cohen DE, Larsen PR, Zavacki AM, Fong LG, Young SG, Lee RT.

Cell Metab. 2011 Nov 2;14(5):671-83. doi: 10.1016/j.cmet.2011.08.011. Epub 2011 Oct 6.

6.

Thioredoxin regulates adipogenesis through thioredoxin-interacting protein (Txnip) protein stability.

Chutkow WA, Lee RT.

J Biol Chem. 2011 Aug 19;286(33):29139-45. doi: 10.1074/jbc.M111.267666. Epub 2011 Jun 24.

7.

Deletion of the alpha-arrestin protein Txnip in mice promotes adiposity and adipogenesis while preserving insulin sensitivity.

Chutkow WA, Birkenfeld AL, Brown JD, Lee HY, Frederick DW, Yoshioka J, Patwari P, Kursawe R, Cushman SW, Plutzky J, Shulman GI, Samuel VT, Lee RT.

Diabetes. 2010 Jun;59(6):1424-34. doi: 10.2337/db09-1212. Epub 2010 Mar 18.

8.

Clinical problem-solving. A crisis in late pregnancy.

Desai AS, Chutkow WA, Edelman E, Economy KE, Dec GW Jr.

N Engl J Med. 2009 Dec 3;361(23):2271-7. doi: 10.1056/NEJMcps0708258. No abstract available.

PMID:
19955528
9.

Interactive medical case. A crisis in late pregnancy.

Ross JJ, Desai AS, Chutkow WA, Economy KE, Dec GW Jr.

N Engl J Med. 2009 Nov 12;361(20):e45. doi: 10.1056/NEJMimc0806409. No abstract available.

PMID:
19916244
10.

Thioredoxin-independent regulation of metabolism by the alpha-arrestin proteins.

Patwari P, Chutkow WA, Cummings K, Verstraeten VL, Lammerding J, Schreiter ER, Lee RT.

J Biol Chem. 2009 Sep 11;284(37):24996-5003. doi: 10.1074/jbc.M109.018093. Epub 2009 Jul 15.

11.

Thioredoxin-interacting protein (Txnip) is a critical regulator of hepatic glucose production.

Chutkow WA, Patwari P, Yoshioka J, Lee RT.

J Biol Chem. 2008 Jan 25;283(4):2397-406. Epub 2007 Nov 12.

12.

Targeted deletion of thioredoxin-interacting protein regulates cardiac dysfunction in response to pressure overload.

Yoshioka J, Imahashi K, Gabel SA, Chutkow WA, Burds AA, Gannon J, Schulze PC, MacGillivray C, London RE, Murphy E, Lee RT.

Circ Res. 2007 Dec 7;101(12):1328-38. Epub 2007 Oct 4.

PMID:
17916779
13.

TXNIP regulates peripheral glucose metabolism in humans.

Parikh H, Carlsson E, Chutkow WA, Johansson LE, Storgaard H, Poulsen P, Saxena R, Ladd C, Schulze PC, Mazzini MJ, Jensen CB, Krook A, Björnholm M, Tornqvist H, Zierath JR, Ridderstråle M, Altshuler D, Lee RT, Vaag A, Groop LC, Mootha VK.

PLoS Med. 2007 May;4(5):e158.

14.

The interaction of thioredoxin with Txnip. Evidence for formation of a mixed disulfide by disulfide exchange.

Patwari P, Higgins LJ, Chutkow WA, Yoshioka J, Lee RT.

J Biol Chem. 2006 Aug 4;281(31):21884-91. Epub 2006 Jun 9.

15.

Episodic coronary artery vasospasm and hypertension develop in the absence of Sur2 K(ATP) channels.

Chutkow WA, Pu J, Wheeler MT, Wada T, Makielski JC, Burant CF, McNally EM.

J Clin Invest. 2002 Jul;110(2):203-8.

16.

Disruption of Sur2-containing K(ATP) channels enhances insulin-stimulated glucose uptake in skeletal muscle.

Chutkow WA, Samuel V, Hansen PA, Pu J, Valdivia CR, Makielski JC, Burant CF.

Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):11760-4. Epub 2001 Sep 18.

17.

Alternative splicing of sur2 Exon 17 regulates nucleotide sensitivity of the ATP-sensitive potassium channel.

Chutkow WA, Makielski JC, Nelson DJ, Burant CF, Fan Z.

J Biol Chem. 1999 May 7;274(19):13656-65.

18.

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