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Items: 1 to 50 of 310

1.

Comorbidity Characterization Among eMERGE Institutions: A Pilot Evaluation with the Johns Hopkins Adjusted Clinical Groups® System.

Taylor CO, Lemke KW, Richards TM, Roe KD, He T, Arruda-Olson A, Carrell D, Denny JC, Hripcsak G, Kiryluk K, Kullo I, Larson EB, Peissig P, Walton NA, Wei-Qi W, Ye Z, Chute CG, Weiner JP.

AMIA Jt Summits Transl Sci Proc. 2019 May 6;2019:145-152. eCollection 2019.

2.

Semantic integration of clinical laboratory tests from electronic health records for deep phenotyping and biomarker discovery.

Zhang XA, Yates A, Vasilevsky N, Gourdine JP, Callahan TJ, Carmody LC, Danis D, Joachimiak MP, Ravanmehr V, Pfaff ER, Champion J, Robasky K, Xu H, Fecho K, Walton NA, Zhu RL, Ramsdill J, Mungall CJ, Köhler S, Haendel MA, McDonald CJ, Vreeman DJ, Peden DB, Bennett TD, Feinstein JA, Martin B, Stefanski AL, Hunter LE, Chute CG, Robinson PN.

NPJ Digit Med. 2019;2. pii: 32. doi: 10.1038/s41746-019-0110-4. Epub 2019 May 2.

3.

Clinical Data: Sources and Types, Regulatory Constraints, Applications.

Ahalt SC, Chute CG, Fecho K, Glusman G, Hadlock J, Taylor CO, Pfaff ER, Robinson PN, Solbrig H, Ta C, Tatonetti N, Weng C; Biomedical Data Translator Consortium.

Clin Transl Sci. 2019 Jul;12(4):329-333. doi: 10.1111/cts.12638. Epub 2019 May 9. No abstract available.

4.

New filovirus disease classification and nomenclature.

Kuhn JH, Adachi T, Adhikari NKJ, Arribas JR, Bah IE, Bausch DG, Bhadelia N, Borchert M, Brantsæter AB, Brett-Major DM, Burgess TH, Chertow DS, Chute CG, Cieslak TJ, Colebunders R, Crozier I, Davey RT, de Clerck H, Delgado R, Evans L, Fallah M, Fischer WA 2nd, Fletcher TE, Fowler RA, Grünewald T, Hall A, Hewlett A, Hoepelman AIM, Houlihan CF, Ippolito G, Jacob ST, Jacobs M, Jakob R, Jacquerioz FA, Kaiser L, Kalil AC, Kamara RF, Kapetshi J, Klenk HD, Kobinger G, Kortepeter MG, Kraft CS, Kratz T, Bosa HSK, Lado M, Lamontagne F, Lane HC, Lobel L, Lutwama J, Lyon GM 3rd, Massaquoi MBF, Massaquoi TA, Mehta AK, Makuma VM, Murthy S, Musoke TS, Muyembe-Tamfum JJ, Nakyeyune P, Nanclares C, Nanyunja M, Nsio-Mbeta J, O'Dempsey T, Pawęska JT, Peters CJ, Piot P, Rapp C, Renaud B, Ribner B, Sabeti PC, Schieffelin JS, Slenczka W, Soka MJ, Sprecher A, Strong J, Swanepoel R, Uyeki TM, van Herp M, Vetter P, Wohl DA, Wolf T, Wolz A, Wurie AH, Yoti Z.

Nat Rev Microbiol. 2019 May;17(5):261-263. doi: 10.1038/s41579-019-0187-4. No abstract available.

5.

Probing the Virtual Proteome to Identify Novel Disease Biomarkers.

Mosley JD, Benson MD, Smith JG, Melander O, Ngo D, Shaffer CM, Ferguson JF, Herzig MS, McCarty CA, Chute CG, Jarvik GP, Gordon AS, Palmer MR, Crosslin DR, Larson EB, Carrell DS, Kullo IJ, Pacheco JA, Peissig PL, Brilliant MH, Kitchner TE, Linneman JG, Namjou B, Williams MS, Ritchie MD, Borthwick KM, Kiryluk K, Mentch FD, Sleiman PM, Karlson EW, Verma SS, Zhu Y, Vasan RS, Yang Q, Denny JC, Roden DM, Gerszten RE, Wang TJ.

Circulation. 2018 Nov 27;138(22):2469-2481. doi: 10.1161/CIRCULATIONAHA.118.036063.

PMID:
30571344
6.

The Return of Actionable Variants Empirical (RAVE) Study, a Mayo Clinic Genomic Medicine Implementation Study: Design and Initial Results.

Kullo IJ, Olson J, Fan X, Jose M, Safarova M, Radecki Breitkopf C, Winkler E, Kochan DC, Snipes S, Pacyna JE, Carney M, Chute CG, Gupta J, Jose S, Venner E, Murugan M, Jiang Y, Zordok M, Farwati M, Philogene M, Smith E, Shaibi GQ, Caraballo P, Freimuth R, Lindor NM, Sharp R, Thibodeau SN.

Mayo Clin Proc. 2018 Nov;93(11):1600-1610. doi: 10.1016/j.mayocp.2018.06.026.

PMID:
30392543
7.

Classification, Ontology, and Precision Medicine.

Haendel MA, Chute CG, Robinson PN.

N Engl J Med. 2018 Oct 11;379(15):1452-1462. doi: 10.1056/NEJMra1615014. Review. No abstract available.

PMID:
30304648
8.

The eMERGE genotype set of 83,717 subjects imputed to ~40 million variants genome wide and association with the herpes zoster medical record phenotype.

Stanaway IB, Hall TO, Rosenthal EA, Palmer M, Naranbhai V, Knevel R, Namjou-Khales B, Carroll RJ, Kiryluk K, Gordon AS, Linder J, Howell KM, Mapes BM, Lin FTJ, Joo YY, Hayes MG, Gharavi AG, Pendergrass SA, Ritchie MD, de Andrade M, Croteau-Chonka DC, Raychaudhuri S, Weiss ST, Lebo M, Amr SS, Carrell D, Larson EB, Chute CG, Rasmussen-Torvik LJ, Roy-Puckelwartz MJ, Sleiman P, Hakonarson H, Li R, Karlson EW, Peterson JF, Kullo IJ, Chisholm R, Denny JC, Jarvik GP; eMERGE Network, Crosslin DR.

Genet Epidemiol. 2019 Feb;43(1):63-81. doi: 10.1002/gepi.22167. Epub 2018 Oct 8.

9.

A study paradigm integrating prospective epidemiologic cohorts and electronic health records to identify disease biomarkers.

Mosley JD, Feng Q, Wells QS, Van Driest SL, Shaffer CM, Edwards TL, Bastarache L, Wei WQ, Davis LK, McCarty CA, Thompson W, Chute CG, Jarvik GP, Gordon AS, Palmer MR, Crosslin DR, Larson EB, Carrell DS, Kullo IJ, Pacheco JA, Peissig PL, Brilliant MH, Linneman JG, Namjou B, Williams MS, Ritchie MD, Borthwick KM, Verma SS, Karnes JH, Weiss ST, Wang TJ, Stein CM, Denny JC, Roden DM.

Nat Commun. 2018 Aug 30;9(1):3522. doi: 10.1038/s41467-018-05624-4.

10.

Empowering genomic medicine by establishing critical sequencing result data flows: the eMERGE example.

Aronson S, Babb L, Ames D, Gibbs RA, Venner E, Connelly JJ, Marsolo K, Weng C, Williams MS, Hartzler AL, Liang WH, Ralston JD, Devine EB, Murphy S, Chute CG, Caraballo PJ, Kullo IJ, Freimuth RR, Rasmussen LV, Wehbe FH, Peterson JF, Robinson JR, Wiley K, Overby Taylor C; eMERGE Network EHRI Working Group.

J Am Med Inform Assoc. 2018 Oct 1;25(10):1375-1381. doi: 10.1093/jamia/ocy051.

11.

Value of Genetics-informed Drug Dosing Guidance in Pregnant Women: A Needs Assessment with Obstetric Healthcare Providers at Johns Hopkins.

Overby CL, Thompkins P, Lehmann H, Chute CG, Sheffield JS.

AMIA Annu Symp Proc. 2018 Apr 16;2017:1342-1351. eCollection 2017.

12.

The rendering of human phenotype and rare diseases in ICD-11.

Chute CG.

J Inherit Metab Dis. 2018 May;41(3):563-569. doi: 10.1007/s10545-018-0172-5. Epub 2018 Mar 29.

13.

Interface Terminologies, Reference Terminologies and Aggregation Terminologies: A Strategy for Better Integration.

Schulz S, Rodrigues JM, Rector A, Chute CG.

Stud Health Technol Inform. 2017;245:940-944.

PMID:
29295238
14.

The Pluripotent Rendering of Clinical Data for Precision Medicine.

Chute CG, Huff SM.

Stud Health Technol Inform. 2017;245:337-340.

PMID:
29295111
15.

Building a semantic web-based metadata repository for facilitating detailed clinical modeling in cancer genome studies.

Sharma DK, Solbrig HR, Tao C, Weng C, Chute CG, Jiang G.

J Biomed Semantics. 2017 Jun 5;8(1):19. doi: 10.1186/s13326-017-0130-4.

16.

Investigating the Genetic Architecture of the PR Interval Using Clinical Phenotypes.

Mosley JD, Shoemaker MB, Wells QS, Darbar D, Shaffer CM, Edwards TL, Bastarache L, McCarty CA, Thompson W, Chute CG, Jarvik GP, Crosslin DR, Larson EB, Kullo IJ, Pacheco JA, Peissig PL, Brilliant MH, Linneman JG, Witte JS, Denny JC, Roden DM.

Circ Cardiovasc Genet. 2017 Apr;10(2). pii: e001482. doi: 10.1161/CIRCGENETICS.116.001482.

17.

Genome-wide study of resistant hypertension identified from electronic health records.

Dumitrescu L, Ritchie MD, Denny JC, El Rouby NM, McDonough CW, Bradford Y, Ramirez AH, Bielinski SJ, Basford MA, Chai HS, Peissig P, Carrell D, Pathak J, Rasmussen LV, Wang X, Pacheco JA, Kho AN, Hayes MG, Matsumoto M, Smith ME, Li R, Cooper-DeHoff RM, Kullo IJ, Chute CG, Chisholm RL, Jarvik GP, Larson EB, Carey D, McCarty CA, Williams MS, Roden DM, Bottinger E, Johnson JA, de Andrade M, Crawford DC.

PLoS One. 2017 Feb 21;12(2):e0171745. doi: 10.1371/journal.pone.0171745. eCollection 2017.

18.

Identification of unique venous thromboembolism-susceptibility variants in African-Americans.

Heit JA, Armasu SM, McCauley BM, Kullo IJ, Sicotte H, Pathak J, Chute CG, Gottesman O, Bottinger EP, Denny JC, Roden DM, Li R, Ritchie MD, de Andrade M.

Thromb Haemost. 2017 Apr 3;117(4):758-768. doi: 10.1160/TH16-08-0652. Epub 2017 Feb 16.

19.

Creating a purpose-driven learning and improving health system: The Johns Hopkins Medicine quality and safety experience.

Pronovost PJ, Mathews SC, Chute CG, Rosen A.

Learn Health Syst. 2016 Dec 15;1(1):e10018. doi: 10.1002/lrh2.10018. eCollection 2017 Jan.

20.

Developing a modular architecture for creation of rule-based clinical diagnostic criteria.

Hong N, Pathak J, Chute CG, Jiang G.

BioData Min. 2016 Oct 21;9:33. eCollection 2016.

21.

Defining a Contemporary Ischemic Heart Disease Genetic Risk Profile Using Historical Data.

Mosley JD, van Driest SL, Wells QS, Shaffer CM, Edwards TL, Bastarache L, McCarty CA, Thompson W, Chute CG, Jarvik GP, Crosslin DR, Larson EB, Kullo IJ, Pacheco JA, Peissig PL, Brilliant MH, Linneman JG, Denny JC, Roden DM.

Circ Cardiovasc Genet. 2016 Dec;9(6):521-530. doi: 10.1161/CIRCGENETICS.116.001530. Epub 2016 Oct 25.

22.

Practical considerations for implementing genomic information resources. Experiences from eMERGE and CSER.

Rasmussen LV, Overby CL, Connolly J, Chute CG, Denny JC, Freimuth R, Hartzler AL, Holm IA, Manzi S, Pathak J, Peissig PL, Smith M, Williams MS, Shirts BH, Stoffel EM, Tarczy-Hornoch P, Rohrer Vitek CR, Wolf WA, Starren J.

Appl Clin Inform. 2016 Sep 21;7(3):870-82. doi: 10.4338/ACI-2016-04-RA-0060.

23.

Health Concept and Knowledge Management: Twenty-five Years of Evolution.

Cornet R, Chute CG.

Yearb Med Inform. 2016 Aug 2;Suppl 1:S32-41. doi: 10.15265/IYS-2016-s037. Review.

24.

Developing a data element repository to support EHR-driven phenotype algorithm authoring and execution.

Jiang G, Kiefer RC, Rasmussen LV, Solbrig HR, Mo H, Pacheco JA, Xu J, Montague E, Thompson WK, Denny JC, Chute CG, Pathak J.

J Biomed Inform. 2016 Aug;62:232-42. doi: 10.1016/j.jbi.2016.07.008. Epub 2016 Jul 5.

25.

SMART-on-FHIR implemented over i2b2.

Wagholikar KB, Mandel JC, Klann JG, Wattanasin N, Mendis M, Chute CG, Mandl KD, Murphy SN.

J Am Med Inform Assoc. 2017 Mar 1;24(2):398-402. doi: 10.1093/jamia/ocw079.

26.

Using Semantic Web technologies for the generation of domain-specific templates to support clinical study metadata standards.

Jiang G, Evans J, Endle CM, Solbrig HR, Chute CG.

J Biomed Semantics. 2016 Mar 3;7:10. doi: 10.1186/s13326-016-0053-5. eCollection 2016.

27.

Genetic variation among 82 pharmacogenes: The PGRNseq data from the eMERGE network.

Bush WS, Crosslin DR, Owusu-Obeng A, Wallace J, Almoguera B, Basford MA, Bielinski SJ, Carrell DS, Connolly JJ, Crawford D, Doheny KF, Gallego CJ, Gordon AS, Keating B, Kirby J, Kitchner T, Manzi S, Mejia AR, Pan V, Perry CL, Peterson JF, Prows CA, Ralston J, Scott SA, Scrol A, Smith M, Stallings SC, Veldhuizen T, Wolf W, Volpi S, Wiley K, Li R, Manolio T, Bottinger E, Brilliant MH, Carey D, Chisholm RL, Chute CG, Haines JL, Hakonarson H, Harley JB, Holm IA, Kullo IJ, Jarvik GP, Larson EB, McCarty CA, Williams MS, Denny JC, Rasmussen-Torvik LJ, Roden DM, Ritchie MD.

Clin Pharmacol Ther. 2016 Aug;100(2):160-9. doi: 10.1002/cpt.350. Epub 2016 Jun 1.

28.

EHR based Genetic Testing Knowledge Base (iGTKB) Development.

Zhu Q, Liu H, Chute CG, Ferber M.

BMC Med Inform Decis Mak. 2015;15 Suppl 4:S3. doi: 10.1186/1472-6947-15-S4-S3. Epub 2015 Nov 25.

29.

Practical considerations in genomic decision support: The eMERGE experience.

Herr TM, Bielinski SJ, Bottinger E, Brautbar A, Brilliant M, Chute CG, Cobb BL, Denny JC, Hakonarson H, Hartzler AL, Hripcsak G, Kannry J, Kohane IS, Kullo IJ, Lin S, Manzi S, Marsolo K, Overby CL, Pathak J, Peissig P, Pulley J, Ralston J, Rasmussen L, Roden DM, Tromp G, Uphoff T, Weng C, Wolf W, Williams MS, Starren J.

J Pathol Inform. 2015 Sep 28;6:50. doi: 10.4103/2153-3539.165999. eCollection 2015.

30.

Clinical element models in the SHARPn consortium.

Oniki TA, Zhuo N, Beebe CE, Liu H, Coyle JF, Parker CG, Solbrig HR, Marchant K, Kaggal VC, Chute CG, Huff SM.

J Am Med Inform Assoc. 2016 Mar;23(2):248-56. doi: 10.1093/jamia/ocv134. Epub 2015 Nov 13.

31.

A conceptual model for translating omic data into clinical action.

Herr TM, Bielinski SJ, Bottinger E, Brautbar A, Brilliant M, Chute CG, Denny J, Freimuth RR, Hartzler A, Kannry J, Kohane IS, Kullo IJ, Lin S, Pathak J, Peissig P, Pulley J, Ralston J, Rasmussen L, Roden D, Tromp G, Williams MS, Starren J.

J Pathol Inform. 2015 Aug 31;6:46. doi: 10.4103/2153-3539.163985. eCollection 2015.

32.

Desiderata for computable representations of electronic health records-driven phenotype algorithms.

Mo H, Thompson WK, Rasmussen LV, Pacheco JA, Jiang G, Kiefer R, Zhu Q, Xu J, Montague E, Carrell DS, Lingren T, Mentch FD, Ni Y, Wehbe FH, Peissig PL, Tromp G, Larson EB, Chute CG, Pathak J, Denny JC, Speltz P, Kho AN, Jarvik GP, Bejan CA, Williams MS, Borthwick K, Kitchner TE, Roden DM, Harris PA.

J Am Med Inform Assoc. 2015 Nov;22(6):1220-30. doi: 10.1093/jamia/ocv112. Epub 2015 Sep 5.

33.

Granular Quality Reporting for Cervical Cytology Testing.

Wagholikar KB, MacLaughlin KL, Chute CG, Greenes RA, Liu H, Chaudhry R.

AMIA Jt Summits Transl Sci Proc. 2015 Mar 25;2015:178-82. eCollection 2015.

34.

A Semantic Web-based System for Mining Genetic Mutations in Cancer Clinical Trials.

Priya S, Jiang G, Dasari S, Zimmermann MT, Wang C, Heflin J, Chute CG.

AMIA Jt Summits Transl Sci Proc. 2015 Mar 25;2015:142-6. eCollection 2015.

35.

Drug Normalization for Cancer Therapeutic and Druggable Genome Target Discovery.

Jiang G, Sohn S, Zimmermann MT, Wang C, Liu H, Chute CG.

AMIA Jt Summits Transl Sci Proc. 2015 Mar 25;2015:72-6. eCollection 2015.

36.

Adverse Drug Events-based Tumor Stratification for Ovarian Cancer Patients Receiving Platinum Therapy.

Wang C, Zimmermann MT, Chute CG, Jiang G.

AMIA Jt Summits Transl Sci Proc. 2015 Mar 23;2015:51-5. eCollection 2015.

37.

A Standards-based Semantic Metadata Repository to Support EHR-driven Phenotype Authoring and Execution.

Jiang G, Solbrig HR, Kiefer R, Rasmussen LV, Mo H, Speltz P, Thompson WK, Denny JC, Chute CG, Pathak J.

Stud Health Technol Inform. 2015;216:1098.

38.
39.

A Pilot Study on Modeling of Diagnostic Criteria Using OWL and SWRL.

Hong N, Jiang G, Pathak J, Chute CG.

Stud Health Technol Inform. 2015;216:1093.

PMID:
26262392
40.

Semantic Alignment between ICD-11 and SNOMED CT.

Rodrigues JM, Robinson D, Della Mea V, Campbell J, Rector A, Schulz S, Brear H, Üstün B, Spackman K, Chute CG, Millar J, Solbrig H, Brand Persson K.

Stud Health Technol Inform. 2015;216:790-4.

PMID:
26262160
41.

A genome-wide association study identifies variants in KCNIP4 associated with ACE inhibitor-induced cough.

Mosley JD, Shaffer CM, Van Driest SL, Weeke PE, Wells QS, Karnes JH, Velez Edwards DR, Wei WQ, Teixeira PL, Bastarache L, Crawford DC, Li R, Manolio TA, Bottinger EP, McCarty CA, Linneman JG, Brilliant MH, Pacheco JA, Thompson W, Chisholm RL, Jarvik GP, Crosslin DR, Carrell DS, Baldwin E, Ralston J, Larson EB, Grafton J, Scrol A, Jouni H, Kullo IJ, Tromp G, Borthwick KM, Kuivaniemi H, Carey DJ, Ritchie MD, Bradford Y, Verma SS, Chute CG, Veluchamy A, Siddiqui MK, Palmer CN, Doney A, MahmoudPour SH, Maitland-van der Zee AH, Morris AD, Denny JC, Roden DM.

Pharmacogenomics J. 2016 Jun;16(3):231-7. doi: 10.1038/tpj.2015.51. Epub 2015 Jul 14.

42.

CSER and eMERGE: current and potential state of the display of genetic information in the electronic health record.

Shirts BH, Salama JS, Aronson SJ, Chung WK, Gray SW, Hindorff LA, Jarvik GP, Plon SE, Stoffel EM, Tarczy-Hornoch PZ, Van Allen EM, Weck KE, Chute CG, Freimuth RR, Grundmeier RW, Hartzler AL, Li R, Peissig PL, Peterson JF, Rasmussen LV, Starren JB, Williams MS, Overby CL.

J Am Med Inform Assoc. 2015 Nov;22(6):1231-42. doi: 10.1093/jamia/ocv065. Epub 2015 Jul 3.

43.

Health information technology data standards get down to business: maturation within domains and the emergence of interoperability.

Richesson RL, Chute CG.

J Am Med Inform Assoc. 2015 May;22(3):492-4. doi: 10.1093/jamia/ocv039. Epub 2015 May 16. No abstract available.

PMID:
25981416
44.

Mining severe drug-drug interaction adverse events using Semantic Web technologies: a case study.

Jiang G, Liu H, Solbrig HR, Chute CG.

BioData Min. 2015 Mar 25;8:12. doi: 10.1186/s13040-015-0044-6. eCollection 2015.

45.

Cancer based pharmacogenomics network supported with scientific evidences: from the view of drug repurposing.

Wang L, Liu H, Chute CG, Zhu Q.

BioData Min. 2015 Feb 25;8:9. doi: 10.1186/s13040-015-0042-8. eCollection 2015.

46.

Transformation of standardized clinical models based on OWL technologies: from CEM to OpenEHR archetypes.

Legaz-García Mdel C, Menárguez-Tortosa M, Fernández-Breis JT, Chute CG, Tao C.

J Am Med Inform Assoc. 2015 May;22(3):536-44. doi: 10.1093/jamia/ocu027. Epub 2015 Feb 10.

47.

Developing the surveillance algorithm for detection of failure to recognize and treat severe sepsis.

Harrison AM, Thongprayoon C, Kashyap R, Chute CG, Gajic O, Pickering BW, Herasevich V.

Mayo Clin Proc. 2015 Feb;90(2):166-75. doi: 10.1016/j.mayocp.2014.11.014. Epub 2015 Jan 6.

48.

Quality Assurance of Cancer Study Common Data Elements Using A Post-Coordination Approach.

Jiang G, Solbrig HR, Prud'hommeaux E, Tao C, Weng C, Chute CG.

AMIA Annu Symp Proc. 2015 Nov 5;2015:659-68. eCollection 2015.

49.

A use case study on late stent thrombosis for ontology-based temporal reasoning and analysis.

Clark K, Sharma D, Qin R, Chute CG, Tao C.

J Biomed Semantics. 2014 Dec 11;5(1):49. doi: 10.1186/2041-1480-5-49. eCollection 2014.

50.

Genetic variants associated with serum thyroid stimulating hormone (TSH) levels in European Americans and African Americans from the eMERGE Network.

Malinowski JR, Denny JC, Bielinski SJ, Basford MA, Bradford Y, Peissig PL, Carrell D, Crosslin DR, Pathak J, Rasmussen L, Pacheco J, Kho A, Newton KM, Li R, Kullo IJ, Chute CG, Chisholm RL, Jarvik GP, Larson EB, McCarty CA, Masys DR, Roden DM, de Andrade M, Ritchie MD, Crawford DC.

PLoS One. 2014 Dec 1;9(12):e111301. doi: 10.1371/journal.pone.0111301. eCollection 2014.

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