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Items: 1 to 50 of 340

1.

Mechanistic insights into histone deposition and nucleosome assembly by the chromatin assembly factor-1.

Sauer PV, Gu Y, Liu WH, Mattiroli F, Panne D, Luger K, Churchill MEA.

Nucleic Acids Res. 2018 Sep 18. doi: 10.1093/nar/gky823. [Epub ahead of print]

PMID:
30239791
2.

Variation in cell-associated unspliced HIV RNA on antiretroviral therapy is associated with the circadian regulator brain-and-muscle-ARNT-like-1.

Chang CC, Naranbhai V, Stern J, Roche M, Dantanarayana A, Ke R, Tennakoon S, Solomon A, Hoh R, Hartogensis W, Hecht FM, Sikaris K, Price DJ, Elliott JH, Deeks SG, Churchill M, Cameron PU, Hengartner N, Perelson AS, Lewin SR.

AIDS. 2018 Sep 24;32(15):2119-2128. doi: 10.1097/QAD.0000000000001937.

PMID:
30005017
3.

Increased hypothalamic microglial activation after viral-induced pneumococcal lung infection is associated with excess serum amyloid A production.

Wang H, Blackall M, Sominsky L, Spencer SJ, Vlahos R, Churchill M, Bozinovski S.

J Neuroinflammation. 2018 Jul 6;15(1):200. doi: 10.1186/s12974-018-1234-1.

4.

Titanium Elastic Nails Versus Spica Cast in Pediatric Femoral Shaft Fractures: A Systematic Review and Meta-analysis of 1012 Patients.

Imam MA, Negida AS, Elgebaly A, Hussain AS, Ernstbrunner L, Javed S, Jacob J, Churchill M, Trikha P, Newman K, Elliott D, Khaleel A.

Arch Bone Jt Surg. 2018 May;6(3):176-188. Review.

5.

Evolution of cranial telescoping in echolocating whales (Cetacea: Odontoceti).

Churchill M, Geisler JH, Beatty BL, Goswami A.

Evolution. 2018 May;72(5):1092-1108. doi: 10.1111/evo.13480. Epub 2018 Apr 25.

PMID:
29624668
6.

Supporting Lesbian, Gay, Bisexual, & Transgender Inclusivity in Long-Term Care Homes: A Canadian Perspective.

Sussman T, Brotman S, MacIntosh H, Chamberland L, MacDonnell J, Daley A, Dumas J, Churchill M.

Can J Aging. 2018 Jun;37(2):121-132. doi: 10.1017/S0714980818000077. Epub 2018 Mar 19.

PMID:
29553004
7.

Mechanism of agonism and antagonism of the Pseudomonas aeruginosa quorum sensing regulator QscR with non-native ligands.

Wysoczynski-Horita CL, Boursier ME, Hill R, Hansen K, Blackwell HE, Churchill MEA.

Mol Microbiol. 2018 May;108(3):240-257. doi: 10.1111/mmi.13930. Epub 2018 Mar 11.

PMID:
29437248
8.

Dietary therapy restores glutamatergic input to orexin/hypocretin neurons after traumatic brain injury in mice.

Elliott JE, De Luche SE, Churchill MJ, Moore C, Cohen AS, Meshul CK, Lim MM.

Sleep. 2018 Mar 1;41(3). doi: 10.1093/sleep/zsx212.

PMID:
29315422
9.

Bone Marrow Myeloid Cells Regulate Myeloid-Biased Hematopoietic Stem Cells via a Histamine-Dependent Feedback Loop.

Chen X, Deng H, Churchill MJ, Luchsinger LL, Du X, Chu TH, Friedman RA, Middelhoff M, Ding H, Tailor YH, Wang ALE, Liu H, Niu Z, Wang H, Jiang Z, Renders S, Ho SH, Shah SV, Tishchenko P, Chang W, Swayne TC, Munteanu L, Califano A, Takahashi R, Nagar KK, Renz BW, Worthley DL, Westphalen CB, Hayakawa Y, Asfaha S, Borot F, Lin CS, Snoeck HW, Mukherjee S, Wang TC.

Cell Stem Cell. 2017 Dec 7;21(6):747-760.e7. doi: 10.1016/j.stem.2017.11.003. Epub 2017 Nov 30.

PMID:
29198940
10.

Functional Impact of Chromatin Remodeling Gene Mutations and Predictive Signature for Therapeutic Response in Bladder Cancer.

Duex JE, Swain KE, Dancik GM, Paucek RD, Owens C, Churchill MEA, Theodorescu D.

Mol Cancer Res. 2018 Jan;16(1):69-77. doi: 10.1158/1541-7786.MCR-17-0260. Epub 2017 Oct 2.

11.

CAF-1-induced oligomerization of histones H3/H4 and mutually exclusive interactions with Asf1 guide H3/H4 transitions among histone chaperones and DNA.

Liu WH, Roemer SC, Port AM, Churchill MEA.

Nucleic Acids Res. 2017 Sep 19;45(16):9809. doi: 10.1093/nar/gkx729. No abstract available.

12.

A toothless dwarf dolphin (Odontoceti: Xenorophidae) points to explosive feeding diversification of modern whales (Neoceti).

Boessenecker RW, Fraser D, Churchill M, Geisler JH.

Proc Biol Sci. 2017 Aug 30;284(1861). pii: 20170531. doi: 10.1098/rspb.2017.0531.

13.

Analysis of Clinical HIV-1 Strains with Resistance to Maraviroc Reveals Strain-Specific Resistance Mutations, Variable Degrees of Resistance, and Minimal Cross-Resistance to Other CCR5 Antagonists.

Flynn JK, Ellenberg P, Duncan R, Ellett A, Zhou J, Sterjovski J, Cashin K, Borm K, Gray LR, Lewis M, Jubb B, Westby M, Lee B, Lewin SR, Churchill M, Roche M, Gorry PR.

AIDS Res Hum Retroviruses. 2017 Dec;33(12):1220-1235. doi: 10.1089/AID.2017.0097. Epub 2017 Sep 26.

PMID:
28797170
14.

Exercise in an animal model of Parkinson's disease: Motor recovery but not restoration of the nigrostriatal pathway.

Churchill MJ, Pflibsen L, Sconce MD, Moore C, Kim K, Meshul CK.

Neuroscience. 2017 Sep 17;359:224-247. doi: 10.1016/j.neuroscience.2017.07.031. Epub 2017 Jul 25.

PMID:
28754312
15.

Histidine decarboxylase (HDC)-expressing granulocytic myeloid cells induce and recruit Foxp3+ regulatory T cells in murine colon cancer.

Chen X, Takemoto Y, Deng H, Middelhoff M, Friedman RA, Chu TH, Churchill MJ, Ma Y, Nagar KK, Tailor YH, Mukherjee S, Wang TC.

Oncoimmunology. 2017 Feb 10;6(3):e1290034. doi: 10.1080/2162402X.2017.1290034. eCollection 2017.

16.

Plastic changes at corticostriatal synapses predict improved motor function in a partial lesion model of Parkinson's disease.

Bentea E, Moore C, Deneyer L, Verbruggen L, Churchill MJ, Hood RL, Meshul CK, Massie A.

Brain Res Bull. 2017 Apr;130:257-267. doi: 10.1016/j.brainresbull.2017.02.005. Epub 2017 Feb 20.

PMID:
28232022
17.

De Novo Mutations in EBF3 Cause a Neurodevelopmental Syndrome.

Sleven H, Welsh SJ, Yu J, Churchill MEA, Wright CF, Henderson A, Horvath R, Rankin J, Vogt J, Magee A, McConnell V, Green A, King MD, Cox H, Armstrong L, Lehman A, Nelson TN; Deciphering Developmental Disorders study; CAUSES study, Williams J, Clouston P, Hagman J, Németh AH.

Am J Hum Genet. 2017 Jan 5;100(1):138-150. doi: 10.1016/j.ajhg.2016.11.020. Epub 2016 Dec 23.

18.

Frequency and Env determinants of HIV-1 subtype C strains from antiretroviral therapy-naive subjects that display incomplete inhibition by maraviroc.

Borm K, Jakobsen MR, Cashin K, Flynn JK, Ellenberg P, Ostergaard L, Lee B, Churchill MJ, Roche M, Gorry PR.

Retrovirology. 2016 Nov 3;13(1):74.

19.

The Cac1 subunit of histone chaperone CAF-1 organizes CAF-1-H3/H4 architecture and tetramerizes histones.

Liu WH, Roemer SC, Zhou Y, Shen ZJ, Dennehey BK, Balsbaugh JL, Liddle JC, Nemkov T, Ahn NG, Hansen KC, Tyler JK, Churchill ME.

Elife. 2016 Sep 30;5. pii: e18023. doi: 10.7554/eLife.18023.

20.

The Origin of High-Frequency Hearing in Whales.

Churchill M, Martinez-Caceres M, de Muizon C, Mnieckowski J, Geisler JH.

Curr Biol. 2016 Aug 22;26(16):2144-9. doi: 10.1016/j.cub.2016.06.004. Epub 2016 Aug 4.

21.

HIV integration and the establishment of latency in CCL19-treated resting CD4(+) T cells require activation of NF-κB.

Saleh S, Lu HK, Evans V, Harisson D, Zhou J, Jaworowski A, Sallmann G, Cheong KY, Mota TM, Tennakoon S, Angelovich TA, Anderson J, Harman A, Cunningham A, Gray L, Churchill M, Mak J, Drummer H, Vatakis DN, Lewin SR, Cameron PU.

Retrovirology. 2016 Jul 26;13(1):49. doi: 10.1186/s12977-016-0284-7.

22.

A HIV-Tat/C4-binding protein chimera encoded by a DNA vaccine is highly immunogenic and contains acute EcoHIV infection in mice.

Tomusange K, Wijesundara D, Gummow J, Garrod T, Li Y, Gray L, Churchill M, Grubor-Bauk B, Gowans EJ.

Sci Rep. 2016 Jun 30;6:29131. doi: 10.1038/srep29131.

23.

Mechanism of Mitochondrial Transcription Factor A Attenuation of CpG-Induced Antibody Production.

Malarkey CS, Gustafson CE, Saifee JF, Torres RM, Churchill ME, Janoff EN.

PLoS One. 2016 Jun 9;11(6):e0157157. doi: 10.1371/journal.pone.0157157. eCollection 2016.

24.

Enamel ultrastructure of fossil and modern pinnipeds: evaluating hypotheses of feeding adaptations in the extinct walrus Pelagiarctos.

Loch C, Boessenecker RW, Churchill M, Kieser J.

Naturwissenschaften. 2016 Jun;103(5-6):44. doi: 10.1007/s00114-016-1366-z. Epub 2016 May 3.

PMID:
27142598
25.

The sea urchin mitochondrial transcription factor A binds and bends DNA efficiently despite its unusually short C-terminal tail.

Malarkey CS, Lionetti C, Deceglie S, Roberti M, Churchill ME, Cantatore P, Loguercio Polosa P.

Mitochondrion. 2016 Jul;29:1-6. doi: 10.1016/j.mito.2016.04.004. Epub 2016 Apr 14.

PMID:
27101895
26.

Strategies to target HIV-1 in the central nervous system.

Gray LR, Brew BJ, Churchill MJ.

Curr Opin HIV AIDS. 2016 Jul;11(4):371-5. doi: 10.1097/COH.0000000000000278. Review.

PMID:
26945147
27.

Nuclear PTEN functions as an essential regulator of SRF-dependent transcription to control smooth muscle differentiation.

Horita H, Wysoczynski CL, Walker LA, Moulton KS, Li M, Ostriker A, Tucker R, McKinsey TA, Churchill ME, Nemenoff RA, Weiser-Evans MC.

Nat Commun. 2016 Mar 4;7:10830. doi: 10.1038/ncomms10830.

28.

Lipidomic dataset of plasma from patients infected with wild type and nef-deficient HIV-1 strain.

Meikle P, Low H, Churchill MJ, Bukrinsky M, Sviridov D.

Data Brief. 2015 Dec 11;6:168-75. doi: 10.1016/j.dib.2015.11.067. eCollection 2016 Mar.

29.

Toxicity and in vitro activity of HIV-1 latency-reversing agents in primary CNS cells.

Gray LR, On H, Roberts E, Lu HK, Moso MA, Raison JA, Papaioannou C, Cheng WJ, Ellett AM, Jacobson JC, Purcell DF, Wesselingh SL, Gorry PR, Lewin SR, Churchill MJ.

J Neurovirol. 2016 Aug;22(4):455-63. doi: 10.1007/s13365-015-0413-4. Epub 2016 Jan 4.

PMID:
26727904
30.

Cyclosporin promotes neurorestoration and cell replacement therapy in pre-clinical models of Parkinson's disease.

Tamburrino A, Churchill MJ, Wan OW, Colino-Sanguino Y, Ippolito R, Bergstrand S, Wolf DA, Herz NJ, Sconce MD, Björklund A, Meshul CK, Decressac M.

Acta Neuropathol Commun. 2015 Dec 14;3:84. doi: 10.1186/s40478-015-0263-6.

31.

HIV reservoirs: what, where and how to target them.

Churchill MJ, Deeks SG, Margolis DM, Siliciano RF, Swanstrom R.

Nat Rev Microbiol. 2016 Jan;14(1):55-60. doi: 10.1038/nrmicro.2015.5. Epub 2015 Nov 30. Review.

PMID:
26616417
32.

Lipid metabolism in patients infected with Nef-deficient HIV-1 strain.

Low H, Cheng L, Di Yacovo MS, Churchill MJ, Meikle P, Bukrinsky M, Hill AF, Sviridov D.

Atherosclerosis. 2016 Jan;244:22-8. doi: 10.1016/j.atherosclerosis.2015.10.103. Epub 2015 Oct 30.

33.

The evolution of aquatic feeding in seals: insights from Enaliarctos (Carnivora: Pinnipedimorpha), the oldest known seal.

Churchill M, Clementz MT.

J Evol Biol. 2016 Feb;29(2):319-34. doi: 10.1111/jeb.12783. Epub 2015 Nov 24.

34.

Efficacy and Safety of Subcutaneous Golimumab in Methotrexate-Naive Patients With Rheumatoid Arthritis: Five-Year Results of a Randomized Clinical Trial.

Emery P, Fleischmann RM, Strusberg I, Durez P, Nash P, Amante EJ, Churchill M, Park W, Pons-Estel B, Han C, Gathany TA, Xu S, Zhou Y, Leu JH, Hsia EC.

Arthritis Care Res (Hoboken). 2016 Jun;68(6):744-52. doi: 10.1002/acr.22759.

35.

IL-17 producing mast cells promote the expansion of myeloid-derived suppressor cells in a mouse allergy model of colorectal cancer.

Chen X, Churchill MJ, Nagar KK, Tailor YH, Chu T, Rush BS, Jiang Z, Wang EB, Renz BW, Wang H, Fung MC, Worthley DL, Mukherjee S, Wang TC.

Oncotarget. 2015 Oct 20;6(32):32966-79. doi: 10.18632/oncotarget.5435.

36.

Molecular Gymnastics: Mechanisms of HIV-1 Resistance to CCR5 Antagonists and Impact on Virus Phenotypes.

Roche M, Borm K, Flynn JK, Lewin SR, Churchill MJ, Gorry PR.

Curr Top Med Chem. 2016;16(10):1091-106. Review.

PMID:
26324043
37.

A Randomized Trial Comparing Disease Activity Measures for the Assessment and Prediction of Response in Rheumatoid Arthritis Patients Initiating Certolizumab Pegol.

Curtis JR, Churchill M, Kivitz A, Samad A, Gauer L, Gervitz L, Koetse W, Melin J, Yazici Y.

Arthritis Rheumatol. 2015 Dec;67(12):3104-12. doi: 10.1002/art.39322.

38.

CNS-specific regulatory elements in brain-derived HIV-1 strains affect responses to latency-reversing agents with implications for cure strategies.

Gray LR, Cowley D, Welsh C, Lu HK, Brew BJ, Lewin SR, Wesselingh SL, Gorry PR, Churchill MJ.

Mol Psychiatry. 2016 Apr;21(4):574-84. doi: 10.1038/mp.2015.111. Epub 2015 Aug 25.

39.

Two high-mobility group box domains act together to underwind and kink DNA.

Sánchez-Giraldo R, Acosta-Reyes FJ, Malarkey CS, Saperas N, Churchill ME, Campos JL.

Acta Crystallogr D Biol Crystallogr. 2015 Jul;71(Pt 7):1423-32. doi: 10.1107/S1399004715007452. Epub 2015 Jun 30.

40.

Inhibition of catechol-O-methyl transferase (COMT) by tolcapone restores reductions in microtubule-associated protein 2 (MAP2) and synaptophysin (SYP) following exposure of neuronal cells to neurotropic HIV.

Lee TT, Chana G, Gorry PR, Ellett A, Bousman CA, Churchill MJ, Gray LR, Everall IP.

J Neurovirol. 2015 Oct;21(5):535-43. doi: 10.1007/s13365-015-0354-y. Epub 2015 Jun 3.

41.

Intervention with exercise restores motor deficits but not nigrostriatal loss in a progressive MPTP mouse model of Parkinson's disease.

Sconce MD, Churchill MJ, Greene RE, Meshul CK.

Neuroscience. 2015 Jul 23;299:156-74. doi: 10.1016/j.neuroscience.2015.04.069. Epub 2015 May 2.

PMID:
25943481
42.

MPTP-induced parkinsonism in mice alters striatal and nigral xCT expression but is unaffected by the genetic loss of xCT.

Bentea E, Sconce MD, Churchill MJ, Van Liefferinge J, Sato H, Meshul CK, Massie A.

Neurosci Lett. 2015 Apr 23;593:1-6. doi: 10.1016/j.neulet.2015.03.013. Epub 2015 Mar 10.

PMID:
25766755
43.

HIV eradication symposium: will the brain be left behind?

Brew BJ, Robertson K, Wright EJ, Churchill M, Crowe SM, Cysique LA, Deeks S, Garcia JV, Gelman B, Gray LR, Johnson T, Joseph J, Margolis DM, Mankowski JL, Spencer B.

J Neurovirol. 2015 Jun;21(3):322-34. doi: 10.1007/s13365-015-0322-6. Epub 2015 Mar 7.

44.

Reliable genotypic tropism tests for the major HIV-1 subtypes.

Cashin K, Gray LR, Harvey KL, Perez-Bercoff D, Lee GQ, Sterjovski J, Roche M, Demarest JF, Drummond F, Harrigan PR, Churchill MJ, Gorry PR.

Sci Rep. 2015 Feb 25;5:8543. doi: 10.1038/srep08543.

45.

The oldest known fur seal.

Boessenecker RW, Churchill M.

Biol Lett. 2015 Feb;11(2):20140835. doi: 10.1098/rsbl.2014.0835.

46.

Intervention with 7,8-dihydroxyflavone blocks further striatal terminal loss and restores motor deficits in a progressive mouse model of Parkinson's disease.

Sconce MD, Churchill MJ, Moore C, Meshul CK.

Neuroscience. 2015 Apr 2;290:454-71. doi: 10.1016/j.neuroscience.2014.12.080. Epub 2015 Feb 2.

PMID:
25655214
47.

The burden of mucosal barrier injury laboratory-confirmed bloodstream infection among hematology, oncology, and stem cell transplant patients.

Metzger KE, Rucker Y, Callaghan M, Churchill M, Jovanovic BD, Zembower TR, Bolon MK.

Infect Control Hosp Epidemiol. 2015 Feb;36(2):119-24. doi: 10.1017/ice.2014.38.

PMID:
25632993
48.

Gremlin 1 identifies a skeletal stem cell with bone, cartilage, and reticular stromal potential.

Worthley DL, Churchill M, Compton JT, Tailor Y, Rao M, Si Y, Levin D, Schwartz MG, Uygur A, Hayakawa Y, Gross S, Renz BW, Setlik W, Martinez AN, Chen X, Nizami S, Lee HG, Kang HP, Caldwell JM, Asfaha S, Westphalen CB, Graham T, Jin G, Nagar K, Wang H, Kheirbek MA, Kolhe A, Carpenter J, Glaire M, Nair A, Renders S, Manieri N, Muthupalani S, Fox JG, Reichert M, Giraud AS, Schwabe RF, Pradere JP, Walton K, Prakash A, Gumucio D, Rustgi AK, Stappenbeck TS, Friedman RA, Gershon MD, Sims P, Grikscheit T, Lee FY, Karsenty G, Mukherjee S, Wang TC.

Cell. 2015 Jan 15;160(1-2):269-84. doi: 10.1016/j.cell.2014.11.042.

49.

Development of novel Asf1-H3/H4 inhibitors.

Miknis GF, Stevens SJ, Smith LE, Ostrov DA, Churchill ME.

Bioorg Med Chem Lett. 2015 Feb 15;25(4):963-8. doi: 10.1016/j.bmcl.2014.11.067. Epub 2014 Dec 4.

50.

Designer antigens for elicitation of broadly neutralizing antibodies against HIV.

Kok T, Gaeguta A, Finnie J, Gorry PR, Churchill M, Li P.

Clin Transl Immunology. 2014 Sep 26;3(9):e24. doi: 10.1038/cti.2014.22. eCollection 2014 Sep.

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