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Items: 1 to 50 of 56

1.

Organoid cystogenesis reveals a critical role of microenvironment in human polycystic kidney disease.

Cruz NM, Song X, Czerniecki SM, Gulieva RE, Churchill AJ, Kim YK, Winston K, Tran LM, Diaz MA, Fu H, Finn LS, Pei Y, Himmelfarb J, Freedman BS.

Nat Mater. 2017 Nov;16(11):1112-1119. doi: 10.1038/nmat4994. Epub 2017 Oct 2.

2.

Gene-Edited Human Kidney Organoids Reveal Mechanisms of Disease in Podocyte Development.

Kim YK, Refaeli I, Brooks CR, Jing P, Gulieva RE, Hughes MR, Cruz NM, Liu Y, Churchill AJ, Wang Y, Fu H, Pippin JW, Lin LY, Shankland SJ, Vogl AW, McNagny KM, Freedman BS.

Stem Cells. 2017 Dec;35(12):2366-2378. doi: 10.1002/stem.2707. Epub 2017 Sep 29.

3.

The New Parent Checklist: A Tool to Promote Parental Reflection.

Keys EM, McNeil DA, Wallace DA, Bostick J, Churchill AJ, Dodd MM.

MCN Am J Matern Child Nurs. 2017 Sep/Oct;42(5):276-282. doi: 10.1097/NMC.0000000000000356.

PMID:
28639998
4.

Genetic evidence that Nkx2.2 acts primarily downstream of Neurog3 in pancreatic endocrine lineage development.

Churchill AJ, Gutiérrez GD, Singer RA, Lorberbaum DS, Fischer KA, Sussel L.

Elife. 2017 Jan 10;6. pii: e20010. doi: 10.7554/eLife.20010.

5.

The Transcriptional Repressive Activity of KRAB Zinc Finger Proteins Does Not Correlate with Their Ability to Recruit TRIM28.

Murphy KE, Shylo NA, Alexander KA, Churchill AJ, Copperman C, García-García MJ.

PLoS One. 2016 Sep 22;11(9):e0163555. doi: 10.1371/journal.pone.0163555. eCollection 2016.

6.

Altered ratios of pro- and anti-angiogenic VEGF-A variants and pericyte expression of DLL4 disrupt vascular maturation in infantile haemangioma.

Ye X, Abou-Rayyah Y, Bischoff J, Ritchie A, Sebire NJ, Watts P, Churchill AJ, Bates DO.

J Pathol. 2016 Jun;239(2):139-51. doi: 10.1002/path.4715.

7.

The carboxyl terminus of VEGF-A is a potential target for anti-angiogenic therapy.

Carter JG, Gammons MV, Damodaran G, Churchill AJ, Harper SJ, Bates DO.

Angiogenesis. 2015 Jan;18(1):23-30. doi: 10.1007/s10456-014-9444-3. Epub 2014 Oct 2.

8.

Regulation of alternative VEGF-A mRNA splicing is a therapeutic target for analgesia.

Hulse RP, Beazley-Long N, Hua J, Kennedy H, Prager J, Bevan H, Qiu Y, Fernandes ES, Gammons MV, Ballmer-Hofer K, Gittenberger de Groot AC, Churchill AJ, Harper SJ, Brain SD, Bates DO, Donaldson LF.

Neurobiol Dis. 2014 Nov;71:245-59. doi: 10.1016/j.nbd.2014.08.012. Epub 2014 Aug 21.

9.

VEGF-A165b is an endogenous neuroprotective splice isoform of vascular endothelial growth factor A in vivo and in vitro.

Beazley-Long N, Hua J, Jehle T, Hulse RP, Dersch R, Lehrling C, Bevan H, Qiu Y, Lagrèze WA, Wynick D, Churchill AJ, Kehoe P, Harper SJ, Bates DO, Donaldson LF.

Am J Pathol. 2013 Sep;183(3):918-29. doi: 10.1016/j.ajpath.2013.05.031. Epub 2013 Jul 6.

10.

Mutational spectrum of the ZEB1 gene in corneal dystrophies supports a genotype-phenotype correlation.

Lechner J, Dash DP, Muszynska D, Hosseini M, Segev F, George S, Frazer DG, Moore JE, Kaye SB, Young T, Simpson DA, Churchill AJ, Héon E, Willoughby CE.

Invest Ophthalmol Vis Sci. 2013 May 3;54(5):3215-23. doi: 10.1167/iovs.13-11781.

PMID:
23599324
11.

Tumor necrosis factor polymorphisms associated with tumor necrosis factor production influence the risk of idiopathic intermediate uveitis.

Atan D, Heissigerova J, Kuffová L, Hogan A, Kilmartin DJ, Forrester JV, Bidwell JL, Dick AD, Churchill AJ.

Mol Vis. 2013;19:184-95. Epub 2013 Jan 28.

12.

Punctate inner choroidopathy and multifocal choroiditis with panuveitis share haplotypic associations with IL10 and TNF loci.

Atan D, Fraser-Bell S, Plskova J, Kuffová L, Hogan A, Tufail A, Kilmartin DJ, Forrester JV, Bidwell JL, Dick AD, Churchill AJ.

Invest Ophthalmol Vis Sci. 2011 Jun 1;52(6):3573-81. doi: 10.1167/iovs.10-6743.

PMID:
21357402
13.

Splicing factor polymorphisms, the control of VEGF isoforms and association with angiogenic eye disease.

Carter JG, Cherry J, Williams K, Turner S, Bates DO, Churchill AJ.

Curr Eye Res. 2011 Apr;36(4):328-35. doi: 10.3109/02713683.2010.548892. Epub 2011 Feb 10.

PMID:
21309690
14.

Cytokine polymorphism in noninfectious uveitis.

Atan D, Fraser-Bell S, Plskova J, Kuffova L, Hogan A, Tufail A, Kilmartin DJ, Forrester JV, Bidwell J, Dick AD, Churchill AJ.

Invest Ophthalmol Vis Sci. 2010 Aug;51(8):4133-42. doi: 10.1167/iovs.09-4583. Epub 2010 Mar 24.

PMID:
20335604
15.

Recombinant human VEGF165b inhibits experimental choroidal neovascularization.

Hua J, Spee C, Kase S, Rennel ES, Magnussen AL, Qiu Y, Varey A, Dhayade S, Churchill AJ, Harper SJ, Bates DO, Hinton DR.

Invest Ophthalmol Vis Sci. 2010 Aug;51(8):4282-8. doi: 10.1167/iovs.09-4360. Epub 2010 Mar 17.

16.

VEGF-A165b is cytoprotective and antiangiogenic in the retina.

Magnussen AL, Rennel ES, Hua J, Bevan HS, Beazley Long N, Lehrling C, Gammons M, Floege J, Harper SJ, Agostini HT, Bates DO, Churchill AJ.

Invest Ophthalmol Vis Sci. 2010 Aug;51(8):4273-81. doi: 10.1167/iovs.09-4296. Epub 2010 Mar 17.

17.

Does acute loss of vision in autosomal dominant optic atrophy occur early in childhood?

Kearns LS, Forrest M, Cohn AC, Churchill AJ, Mackey DA.

Ophthalmic Genet. 2010 Mar;31(1):44-6. doi: 10.3109/13816810903479842.

PMID:
20141358
18.

Analysis of SERPING1 and its association with age-related macular degeneration.

Carter JG, Churchill AJ.

Acta Ophthalmol. 2011 Mar;89(2):e212-3. doi: 10.1111/j.1755-3768.2009.01788.x. No abstract available.

19.

VEGF(121)b, a new member of the VEGF(xxx)b family of VEGF-A splice isoforms, inhibits neovascularisation and tumour growth in vivo.

Rennel ES, Varey AH, Churchill AJ, Wheatley ER, Stewart L, Mather S, Bates DO, Harper SJ.

Br J Cancer. 2009 Oct 6;101(7):1183-93. doi: 10.1038/sj.bjc.6605249. Epub 2009 Aug 25.

20.

β-Defensin 1 haplotype associated with postoperative endophthalmitis.

Carter JG, West SK, Painter S, Haynes RJ, Churchill AJ.

Acta Ophthalmol. 2010 Nov;88(7):786-90. doi: 10.1111/j.1755-3768.2009.01534.x.

21.

Clinical phenotype of posterior polymorphous corneal dystrophy in a family with a novel ZEB1 mutation.

Nguyen DQ, Hosseini M, Billingsley G, Héon E, Churchill AJ.

Acta Ophthalmol. 2010 Sep;88(6):695-9. doi: 10.1111/j.1755-3768.2009.01511.x.

22.

A pregnancy wellness guide to enhance care through self-assessment, personal reflection, and self-referral.

Wallace DA, Dodd MM, McNeil DA, Churchill AJ, Oelke ND, Arnold SL, Oberle K.

J Obstet Gynecol Neonatal Nurs. 2009 Mar-Apr;38(2):134-47. doi: 10.1111/j.1552-6909.2009.01008.x.

PMID:
19323710
23.

Expression of pro- and anti-angiogenic isoforms of VEGF is differentially regulated by splicing and growth factors.

Nowak DG, Woolard J, Amin EM, Konopatskaya O, Saleem MA, Churchill AJ, Ladomery MR, Harper SJ, Bates DO.

J Cell Sci. 2008 Oct 15;121(Pt 20):3487-95. doi: 10.1242/jcs.016410.

24.

VEGF polymorphisms are associated with severity of diabetic retinopathy.

Churchill AJ, Carter JG, Ramsden C, Turner SJ, Yeung A, Brenchley PE, Ray DW.

Invest Ophthalmol Vis Sci. 2008 Aug;49(8):3611-6. doi: 10.1167/iovs.07-1383. Epub 2008 Apr 25.

PMID:
18441306
25.

A case of bilateral endophthalmitis and carriage of beta-defensin 1 44CC genotype.

Carter J, Churchill AJ, Gorman C, Haynes R.

Br J Ophthalmol. 2007 Sep;91(9):1249-50. No abstract available.

26.

The effects of sex, ethnicity, and sexual orientation on self-measured digit ratio (2D:4D).

Manning JT, Churchill AJ, Peters M.

Arch Sex Behav. 2007 Apr;36(2):223-33.

PMID:
17373585
27.

VEGF polymorphisms are associated with neovascular age-related macular degeneration.

Churchill AJ, Carter JG, Lovell HC, Ramsden C, Turner SJ, Yeung A, Escardo J, Atan D.

Hum Mol Genet. 2006 Oct 1;15(19):2955-61. Epub 2006 Aug 29.

PMID:
16940309
28.

VEGF165b, an endogenous C-terminal splice variant of VEGF, inhibits retinal neovascularization in mice.

Konopatskaya O, Churchill AJ, Harper SJ, Bates DO, Gardiner TA.

Mol Vis. 2006 May 26;12:626-32.

29.

Cytokine gene polymorphism in sympathetic ophthalmia.

Atan D, Turner SJ, Kilmartin DJ, Forrester JV, Bidwell J, Dick AD, Churchill AJ.

Invest Ophthalmol Vis Sci. 2005 Nov;46(11):4245-50.

PMID:
16249504
30.

Diabetic retinopathy is associated with a switch in splicing from anti- to pro-angiogenic isoforms of vascular endothelial growth factor.

Perrin RM, Konopatskaya O, Qiu Y, Harper S, Bates DO, Churchill AJ.

Diabetologia. 2005 Nov;48(11):2422-7. Epub 2005 Sep 29.

PMID:
16193288
31.

A compound heterozygous change found in Peters' anomaly.

Churchill AJ, Yeung A.

Mol Vis. 2005 Jan 21;11:66-70.

32.

Quantitative MR image analysis in subjects with defects in the PAX6 gene.

Free SL, Mitchell TN, Williamson KA, Churchill AJ, Shorvon SD, Moore AT, van Heyningen V, Sisodiya SM.

Neuroimage. 2003 Dec;20(4):2281-90.

PMID:
14683729
33.

Polymorphisms in OPA1 are associated with normal tension glaucoma.

Powell BL, Toomes C, Scott S, Yeung A, Marchbank NJ, Spry PG, Lumb R, Inglehearn CF, Churchill AJ.

Mol Vis. 2003 Sep 22;9:460-4.

34.

Relative contribution of footwear to the efficacy of ankle-foot orthoses.

Churchill AJ, Halligan PW, Wade DT.

Clin Rehabil. 2003 Aug;17(5):553-7.

PMID:
12952163
35.

Polymicrogyria and absence of pineal gland due to PAX6 mutation.

Mitchell TN, Free SL, Williamson KA, Stevens JM, Churchill AJ, Hanson IM, Shorvon SD, Moore AT, van Heyningen V, Sisodiya SM.

Ann Neurol. 2003 May;53(5):658-63.

PMID:
12731001
36.

Training and testing competence in direct ophthalmoscopy.

Levy A, Churchill AJ.

Med Educ. 2003 May;37(5):483-4. No abstract available.

PMID:
12709208
37.

Public opinion on weekend and evening outpatient clinics.

Churchill AJ, Gibbon C, Anand S, McKibbin M.

Br J Ophthalmol. 2003 Mar;87(3):257-8. No abstract available.

38.

Importance of molecular testing in dominant optic atrophy.

Patel N, Churchill AJ, Toomes C, Marchbank NJ, Inglehearn CF, Foulds N, Moosavi A, Teimory M.

Br J Ophthalmol. 2002 Nov;86(11):1314-5. No abstract available.

39.

RIVCAM: a simple video-based kinematic analysis for clinical disorders of gait.

Churchill AJ, Halligan PW, Wade DT.

Comput Methods Programs Biomed. 2002 Nov;69(3):197-209.

PMID:
12204448
40.

Deletion of the OPA1 gene in a dominant optic atrophy family: evidence that haploinsufficiency is the cause of disease.

Marchbank NJ, Craig JE, Leek JP, Toohey M, Churchill AJ, Markham AF, Mackey DA, Toomes C, Inglehearn CF.

J Med Genet. 2002 Aug;39(8):e47. No abstract available.

41.

Spectrum, frequency and penetrance of OPA1 mutations in dominant optic atrophy.

Toomes C, Marchbank NJ, Mackey DA, Craig JE, Newbury-Ecob RA, Bennett CP, Vize CJ, Desai SP, Black GC, Patel N, Teimory M, Markham AF, Inglehearn CF, Churchill AJ.

Hum Mol Genet. 2001 Jun 15;10(13):1369-78.

PMID:
11440989
42.

A high-density transcript map of the human dominant optic atrophy OPA1 gene locus and re-evaluation of evidence for a founder haplotype.

Murton NJ, French L, Toomes C, Joseph SS, Rehman I, Hopkins BL, Inglehearn CF, Churchill AJ.

Cytogenet Cell Genet. 2001;92(1-2):97-102.

PMID:
11306804
43.

Clinical manifestations of protein C deficiency: a spectrum within one family.

Churchill AJ, Gallagher MJ, Bradbury JA, Minford AM.

Br J Ophthalmol. 2001 Feb;85(2):241-2. No abstract available.

44.

Genetic screening in a large family with juvenile onset primary open angle glaucoma.

Booth AP, Anwar R, Chen H, Churchill AJ, Jay J, Polansky J, Nguyen T, Markham AF.

Br J Ophthalmol. 2000 Jul;84(7):722-6.

45.

A novel deletion (IVS11+3del4) identified in the human PAX6 gene in a patient with aniridia.

Murton NJ, Rehman I, Black GC, Inglehearn CF, Churchill AJ.

Hum Mutat. 2000 Jun;15(6):582. No abstract available.

PMID:
10862096
46.

Prenatal diagnosis of aniridia.

Churchill AJ, Hanson IM, Markham AF.

Ophthalmology. 2000 Jun;107(6):1153-6.

PMID:
10857836
47.

What factors influence cataract waiting list time?

Churchill AJ, Vize CJ, Stewart OG, Backhouse O.

Br J Ophthalmol. 2000 Apr;84(4):429-31.

48.

Science! Why should the clinician care?

Churchill AJ.

Br J Ophthalmol. 1999 Jun;83(6):638-9. No abstract available.

49.

PAX 6 is normal in most cases of Peters' anomaly.

Churchill AJ, Booth AP, Anwar R, Markham AF.

Eye (Lond). 1998;12 ( Pt 2):299-303.

PMID:
9683959
50.

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