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Cases in Precision Medicine: The Role of Pharmacogenetics in Precision Prescribing.

Lin B, Chung WK.

Ann Intern Med. 2019 May 21. doi: 10.7326/M18-2357. [Epub ahead of print]


Alternative polyadenylation of single cells delineates cell types and serves as a prognostic marker in early stage breast cancer.

Kim N, Chung W, Eum HH, Lee HO, Park WY.

PLoS One. 2019 May 17;14(5):e0217196. doi: 10.1371/journal.pone.0217196. eCollection 2019.


Comparison of 24 hours Ambulatory Central Blood Pressure Reduction Efficacy between Fixed Amlodipine or Up-titrated Hydrochlorothiazide plus Losartan : The K-Central Study.

Cho EJ, Lee HY, Sung KC, Park S, Sohn IS, Park CG, Choi DJ, Ha JW, Ahn YK, Shin J, Hong SJ, Kim SK, Chung WJ, Yoo BS, Hong TJ, Youn HJ, Cho MC, Chae SC, Kim YJ, Kim CJ.

Am J Hypertens. 2019 May 10. pii: hpz050. doi: 10.1093/ajh/hpz050. [Epub ahead of print]


United States Pulmonary Hypertension Scientific Registry (USPHSR): rationale, design, and clinical implications.

Elliott CG, Austin ED, Badesch D, Badlam J, Benza RL, Chung WK, Farber HW, Feldkircher K, Frost AE, Poms AD, Lutz KA, Pauciulo MW, Yu C, Nichols WC.

Pulm Circ. 2019 Apr-Jun;9(2):2045894019851696. doi: 10.1177/2045894019851696.


Treatment Outcomes of Cavernous Sinus Dural Arteriovenous Fistulas: Comparison of Radiosurgery and Endovascular Embolisation.

Yang HC, Lin CJ, Luo CB, Lee CC, Wu HM, Guo WY, Chung WY, Liu KD.

Clin Neuroradiol. 2019 May 16. doi: 10.1007/s00062-019-00787-z. [Epub ahead of print]


Gender differences of in-hospital outcomes in patients undergoing percutaneous coronary intervention in the drug-eluting stent era.

Kim HL, Jang JS, Kim MA, Seo JB, Chung WY, Kim SH, Park SJ, Youn TJ, Yoon MH, Lee JH, Chang K, Jeong MH, Choi RK, Hong MK, Kim HS.

Medicine (Baltimore). 2019 May;98(20):e15557. doi: 10.1097/MD.0000000000015557.


Radiosurgery for Dural Arteriovenous Fistulas.

Yang HC, Lee CC, Pan DHC, Chung WY.

Prog Neurol Surg. 2019;34:248-259. doi: 10.1159/000493071. Epub 2019 May 16.


Real-time analysis of living animals and rapid screening of human fluid samples using remote sampling electrospray ionization mass spectrometry.

Yoshimura K, Yamada Y, Ninomiya S, Chung WY, Chang YT, Dennison AR, Hiraoka K, Takeda S, Chen LC.

J Pharm Biomed Anal. 2019 Apr 30;172:372-378. doi: 10.1016/j.jpba.2019.04.050. [Epub ahead of print]


Targeted Delivery of Curcumin Rescues Endoplasmic Reticulum-Retained Mutant NOX2 Protein and Avoids Leukocyte Apoptosis.

Yen CL, Liao YC, Chen RF, Huang YF, Chung WC, Lo PC, Chang CF, Wu PC, Shieh DB, Jiang ST, Shieh CC.

J Immunol. 2019 May 13. pii: ji1801599. doi: 10.4049/jimmunol.1801599. [Epub ahead of print]


Cases in Precision Medicine: Genetic Assessment After a Sudden Cardiac Death in the Family.

Laracuente R, Waase MP, Kalia I, Wilde AAM, Chung WK.

Ann Intern Med. 2019 May 14. doi: 10.7326/M18-2359. [Epub ahead of print]


Current trends in the features of male thyroid cancer: Retrospective evaluation of their prognostic value.

Kim MJ, Lee SG, Kim K, Lee CR, Kang SW, Lee J, Nam KH, Chung WY, Jeong JJ.

Medicine (Baltimore). 2019 May;98(19):e15559. doi: 10.1097/MD.0000000000015559.


Relationships between dental hygienists' work environment and patient safety culture.

Choi EM, Mun SJ, Chung WG, Noh HJ.

BMC Health Serv Res. 2019 May 10;19(1):299. doi: 10.1186/s12913-019-4136-8.


Surgical outcomes of laparoscopic adrenalectomy for primary hyperaldosteronism: 20 years of experience in a single institution.

Kim K, Kim JK, Lee CR, Kang SW, Lee J, Jeong JJ, Nam KH, Chung WY.

Ann Surg Treat Res. 2019 May;96(5):223-229. doi: 10.4174/astr.2019.96.5.223. Epub 2019 Apr 24.


PKM2 enhances cancer invasion via ETS-1-dependent induction of matrix metalloproteinase in oral squamous cell carcinoma cells.

Park YJ, Kim JY, Lee DY, Zhang X, Bazarsad S, Chung WY, Kim J.

PLoS One. 2019 May 9;14(5):e0216661. doi: 10.1371/journal.pone.0216661. eCollection 2019.


Health-related quality of life associated with different cancer treatments in Chinese breast cancer survivors in Taiwan.

Ou HT, Chung WP, Su PF, Lin TH, Lin JY, Wen YC, Fang WT.

Eur J Cancer Care (Engl). 2019 May 8:e13069. doi: 10.1111/ecc.13069. [Epub ahead of print]


Nylon mesh-based sample holder for fixed-target serial femtosecond crystallography.

Lee D, Baek S, Park J, Lee K, Kim J, Lee SJ, Chung WK, Lee JL, Cho Y, Nam KH.

Sci Rep. 2019 May 6;9(1):6971. doi: 10.1038/s41598-019-43485-z.


Anoctamin 8 tethers endoplasmic reticulum and plasma membrane for assembly of Ca2+ signaling complexes at the ER/PM compartment.

Jha A, Chung WY, Vachel L, Maleth J, Lake S, Zhang G, Ahuja M, Muallem S.

EMBO J. 2019 May 6. pii: e101452. doi: 10.15252/embj.2018101452. [Epub ahead of print]


Non-cell autonomous modulation of tyrosine hydroxylase by HMGB1 released from astrocytes in an acute MPTP-induced Parkinsonian mouse model.

Kim SJ, Ryu MJ, Han J, Jang Y, Lee MJ, Ju X, Ryu I, Lee YL, Oh E, Chung W, Heo JY, Kweon GR.

Lab Invest. 2019 May 1. doi: 10.1038/s41374-019-0254-5. [Epub ahead of print]


A pathogenic CtBP1 missense mutation causes altered cofactor binding and transcriptional activity.

Beck DB, Subramanian T, Vijayalingam S, Ezekiel UR, Donkervoort S, Yang ML, Dubbs HA, Ortiz-Gonzalez XR, Lakhani S, Segal D, Au M, Graham JM Jr, Verma S, Waggoner D, Shinawi M, Bönnemann CG, Chung WK, Chinnadurai G.

Neurogenetics. 2019 Apr 30. doi: 10.1007/s10048-019-00578-1. [Epub ahead of print]


Correction: Evaluation of the cost and effectiveness of diverse recruitment methods for a genetic screening study.

Rasouly HM, Wynn J, Marasa M, Reingold R, Chatterjee D, Kapoor S, Piva S, Kil BH, Mu X, Alvarez M, Nestor J, Mehl K, Revah-Politi A, Lippa N, Ernst ME, Bier L, Espinal A, Haser B, Sinha A, Halim I, Fasel D, Cuneo N, Thompson JJ, Verbitsky M, Cohn EG, Goldman J, Marder K, Klitzman RL, Orjuela MA, So YS, Fedotov A, Crew KD, Kiryluk K, Appelbaum PS, Weng C, Siegel K, Gharavi AG, Chung WK.

Genet Med. 2019 May 1. doi: 10.1038/s41436-019-0528-8. [Epub ahead of print]


A preliminary report of longitudinal white matter alterations in patients with end-stage renal disease: A three-year diffusion tensor imaging study.

Chou MC, Ko CH, Hsieh TJ, Chang JM, Chung WS.

PLoS One. 2019 Apr 30;14(4):e0215942. doi: 10.1371/journal.pone.0215942. eCollection 2019.


The 10th International Congress on Cutaneous Adverse Drug Reactions, Shimane, Japan, 2018: Focus on New Discoveries.

Olteanu C, Shear NH, Morita E, Chung WH, Niihara H, Matsukura S, Hashimoto R, Dodiuk-Gad RP.

Drug Saf. 2019 Jun;42(6):797-801. doi: 10.1007/s40264-019-00818-1. No abstract available.


Ticagrelor Does Not Improve Endothelial Dysfunction in Stable Survivors of Acute Coronary Syndrome.

Lim S, Choo EH, Kim CJ, Choi IJ, Lee KY, Hwang BH, Lee JM, Chung WS, Chang K.

J Cardiovasc Pharmacol Ther. 2019 Apr 29:1074248419841640. doi: 10.1177/1074248419841640. [Epub ahead of print]


Precision Medicine in Internal Medicine.

Kiryluk K, Goldstein DB, Rowe JW, Gharavi AG, Wapner R, Chung WK.

Ann Intern Med. 2019 Apr 30. doi: 10.7326/M18-0425. [Epub ahead of print]


Cases in Precision Medicine: When Patients Present With Direct-to-Consumer Genetic Test Results.

Artin MG, Stiles D, Kiryluk K, Chung WK.

Ann Intern Med. 2019 Apr 30. doi: 10.7326/M18-2356. [Epub ahead of print]


Associations among Geriatric Nutrition Risk Index, bone mineral density, body composition and handgrip strength in patients receiving hemodialysis.

Chen SC, Chung WS, Wu PY, Huang JC, Chiu YW, Chang JM, Chen HC.

Nutrition. 2019 Feb 26;65:6-12. doi: 10.1016/j.nut.2019.02.013. [Epub ahead of print]


Validity of a nationwide medication record system in the Netherlands.

Uitvlugt EB, van den Bemt BJF, Chung WL, Dik J, van den Bemt PMLA, Karapinar-Çarkit F.

Int J Clin Pharm. 2019 Apr 27. doi: 10.1007/s11096-019-00839-x. [Epub ahead of print]


An Enhanced Multiplication of RF Energy Harvesting Efficiency Using Relay Resonator for Food Monitoring.

Cao XT, Chung WY.

Sensors (Basel). 2019 Apr 26;19(9). pii: E1963. doi: 10.3390/s19091963.


Stasis index from hemodynamic analysis using quantitative DSA correlates with hemorrhage of supratentorial arteriovenous malformation: a cross-sectional study.

Lin TM, Yang HC, Lee CC, Wu HM, Hu YS, Luo CB, Guo WY, Kao YH, Chung WY, Lin CJ.

J Neurosurg. 2019 Apr 26:1-9. doi: 10.3171/2019.1.JNS183386. [Epub ahead of print]


Development of the State Optimism Measure.

Millstein RA, Chung WJ, Hoeppner BB, Boehm JK, Legler SR, Mastromauro CA, Huffman JC.

Gen Hosp Psychiatry. 2019 May - Jun;58:83-93. doi: 10.1016/j.genhosppsych.2019.04.002. Epub 2019 Apr 4.


Amino acid signatures of HLA Class-I and II molecules are strongly associated with SLE susceptibility and autoantibody production in Eastern Asians.

Molineros JE, Looger LL, Kim K, Okada Y, Terao C, Sun C, Zhou XJ, Raj P, Kochi Y, Suzuki A, Akizuki S, Nakabo S, Bang SY, Lee HS, Kang YM, Suh CH, Chung WT, Park YB, Choe JY, Shim SC, Lee SS, Zuo X, Yamamoto K, Li QZ, Shen N, Porter LL, Harley JB, Chua KH, Zhang H, Wakeland EK, Tsao BP, Bae SC, Nath SK.

PLoS Genet. 2019 Apr 25;15(4):e1008092. doi: 10.1371/journal.pgen.1008092. eCollection 2019 Apr.


Gamma knife radiosurgery for the treatment of cavernous sinus meningiomas: post-treatment long-term clinical outcomes, complications, and volume changes.

Hung YC, Lee CC, Guo WY, Shiau CY, Chang YC, Pan DH, Sheehan JP, Chung WY.

J Neurooncol. 2019 Apr 24. doi: 10.1007/s11060-019-03090-6. [Epub ahead of print]


Evaluation of Bleeding Risk in Patients with Acute Myocardial Infarction Undergoing Transradial Percutaneous Coronary Intervention.

Chen TY, Chung WJ, Lee CH, Wu PJ, Hsueh SK, Tsai TH, Chen CJ, Wu CJ, Cheng CI.

Int Heart J. 2019 Apr 25. doi: 10.1536/ihj.18-377. [Epub ahead of print]


Implementation of an experimental and computational tool set to study protein-mAb interactions.

Ranjan S, Chung WK, Zhu M, Robbins D, Cramer SM.

Biotechnol Prog. 2019 Apr 24:e2825. doi: 10.1002/btpr.2825. [Epub ahead of print]


Points to consider in the reevaluation and reanalysis of genomic test results: a statement of the American College of Medical Genetics and Genomics (ACMG).

Deignan JL, Chung WK, Kearney HM, Monaghan KG, Rehder CW, Chao EC; ACMG Laboratory Quality Assurance Committee.

Genet Med. 2019 Apr 24. doi: 10.1038/s41436-019-0478-1. [Epub ahead of print] No abstract available.


Homozygous non-canonical splice variant in LSM1 in two siblings with multiple congenital anomalies and global developmental delays.

Okur V, LeDuc CA, Guzman E, Valivullah ZM, Anyane-Yeboa K, Chung WK.

Cold Spring Harb Mol Case Stud. 2019 Apr 22. pii: mcs.a004101. doi: 10.1101/mcs.a004101. [Epub ahead of print]


Regular use of aspirin and other non-steroidal anti-inflammatory drugs and breast cancer risk for women at familial or genetic risk: a cohort study.

Kehm RD, Hopper JL, John EM, Phillips KA, MacInnis RJ, Dite GS, Milne RL, Liao Y, Zeinomar N, Knight JA, Southey MC, Vahdat L, Kornhauser N, Cigler T, Chung WK, Giles GG, McLachlan SA, Friedlander ML, Weideman PC, Glendon G, Nesci S; kConFab Investigators, Andrulis IL, Buys SS, Daly MB, Terry MB.

Breast Cancer Res. 2019 Apr 18;21(1):52. doi: 10.1186/s13058-019-1135-y.


A Technology-Computer-Aided-Design-Based Reliability Prediction Model for DRAM Storage Capacitors.

Choi WY, Yoon G, Chung WY, Cho Y, Shin S, Ahn KH.

Micromachines (Basel). 2019 Apr 17;10(4). pii: E256. doi: 10.3390/mi10040256.


Quantitative analysis of effects of the grid specifications on the quality of digital radiography images.

Lee S, Chung W.

Australas Phys Eng Sci Med. 2019 Apr 15. doi: 10.1007/s13246-019-00756-3. [Epub ahead of print]


Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer.

Ferreira MA, Gamazon ER, Al-Ejeh F, Aittomäki K, Andrulis IL, Anton-Culver H, Arason A, Arndt V, Aronson KJ, Arun BK, Asseryanis E, Azzollini J, Balmaña J, Barnes DR, Barrowdale D, Beckmann MW, Behrens S, Benitez J, Bermisheva M, Białkowska K, Blomqvist C, Bogdanova NV, Bojesen SE, Bolla MK, Borg A, Brauch H, Brenner H, Broeks A, Burwinkel B, Caldés T, Caligo MA, Campa D, Campbell I, Canzian F, Carter J, Carter BD, Castelao JE, Chang-Claude J, Chanock SJ, Christiansen H, Chung WK, Claes KBM, Clarke CL; EMBRACE Collaborators; GC-HBOC Study Collaborators; GEMO Study Collaborators, Couch FJ, Cox A, Cross SS, Czene K, Daly MB, de la Hoya M, Dennis J, Devilee P, Diez O, Dörk T, Dunning AM, Dwek M, Eccles DM, Ejlertsen B, Ellberg C, Engel C, Eriksson M, Fasching PA, Fletcher O, Flyger H, Friedman E, Frost D, Gabrielson M, Gago-Dominguez M, Ganz PA, Gapstur SM, Garber J, García-Closas M, García-Sáenz JA, Gaudet MM, Giles GG, Glendon G, Godwin AK, Goldberg MS, Goldgar DE, González-Neira A, Greene MH, Gronwald J, Guénel P, Haiman CA, Hall P, Hamann U, He W, Heyworth J, Hogervorst FBL, Hollestelle A, Hoover RN, Hopper JL, Hulick PJ, Humphreys K, Imyanitov EN; ABCTB Investigators; HEBON Investigators; BCFR Investigators, Isaacs C, Jakimovska M, Jakubowska A, James PA, Janavicius R, Jankowitz RC, John EM, Johnson N, Joseph V, Karlan BY, Khusnutdinova E, Kiiski JI, Ko YD, Jones ME, Konstantopoulou I, Kristensen VN, Laitman Y, Lambrechts D, Lazaro C, Leslie G, Lester J, Lesueur F, Lindström S, Long J, Loud JT, Lubiński J, Makalic E, Mannermaa A, Manoochehri M, Margolin S, Maurer T, Mavroudis D, McGuffog L, Meindl A, Menon U, Michailidou K, Miller A, Montagna M, Moreno F, Moserle L, Mulligan AM, Nathanson KL, Neuhausen SL, Nevanlinna H, Nevelsteen I, Nielsen FC, Nikitina-Zake L, Nussbaum RL, Offit K, Olah E, Olopade OI, Olsson H, Osorio A, Papp J, Park-Simon TW, Parsons MT, Pedersen IS, Peixoto A, Peterlongo P, Pharoah PDP, Plaseska-Karanfilska D, Poppe B, Presneau N, Radice P, Rantala J, Rennert G, Risch HA, Saloustros E, Sanden K, Sawyer EJ, Schmidt MK, Schmutzler RK, Sharma P, Shu XO, Simard J, Singer CF, Soucy P, Southey MC, Spinelli JJ, Spurdle AB, Stone J, Swerdlow AJ, Tapper WJ, Taylor JA, Teixeira MR, Terry MB, Teulé A, Thomassen M, Thöne K, Thull DL, Tischkowitz M, Toland AE, Torres D, Truong T, Tung N, Vachon CM, van Asperen CJ, van den Ouweland AMW, van Rensburg EJ, Vega A, Viel A, Wang Q, Wappenschmidt B, Weitzel JN, Wendt C, Winqvist R, Yang XR, Yannoukakos D, Ziogas A, Kraft P, Antoniou AC, Zheng W, Easton DF, Milne RL, Beesley J, Chenevix-Trench G.

Nat Commun. 2019 Apr 15;10(1):1741. doi: 10.1038/s41467-018-08053-5.


Increase Paclitaxel Sensitivity to Better Suppress Serous Epithelial Ovarian Cancer via Ablating Androgen Receptor/Aryl Hydrocarbon Receptor-ABCG2 Axis.

Chung WM, Ho YP, Chang WC, Dai YC, Chen L, Hung YC, Ma WL.

Cancers (Basel). 2019 Apr 2;11(4). pii: E463. doi: 10.3390/cancers11040463.


Usefulness of a Positive Psychology-Motivational Interviewing Intervention to Promote Positive Affect and Physical Activity After an Acute Coronary Syndrome.

Huffman JC, Feig EH, Millstein RA, Freedman M, Healy BC, Chung WJ, Amonoo HL, Malloy L, Slawsby E, Januzzi JL, Celano CM.

Am J Cardiol. 2019 Jun 15;123(12):1906-1914. doi: 10.1016/j.amjcard.2019.03.023. Epub 2019 Mar 19.


HLA-B*57:01 confers genetic susceptibility to carbamazepine-induced SJS/TEN in Europeans.

Mockenhaupt M, Wang CW, Hung SI, Sekula P, Schmidt AH, Pan RY, Chen CB, Dunant A, Gouvello SL, Schumacher M, Valeyrie-Allanore L, Bellon T, Kardaun SH, Jan YS, Chung WH, Roujeau JC; RegiSCAR group.

Allergy. 2019 Apr 11. doi: 10.1111/all.13821. [Epub ahead of print] No abstract available.


Morphologic Change of Flow-Related Aneurysms in Brain Arteriovenous Malformations after Stereotactic Radiosurgery.

Tsuei YS, Luo CB, Fay LY, Yang HC, Guo WY, Wu HM, Chung WY, Teng MMH.

AJNR Am J Neuroradiol. 2019 Apr;40(4):675-680. doi: 10.3174/ajnr.A6018.


Lysosomal Machinery Drives Extracellular Acidification to Direct Non-apoptotic Cell Death.

Mondragon AA, Yalonetskaya A, Ortega AJ, Zhang Y, Naranjo O, Elguero J, Chung WS, McCall K.

Cell Rep. 2019 Apr 2;27(1):11-19.e3. doi: 10.1016/j.celrep.2019.03.034.


Whole genome sequencing analysis of horse populations inhabiting the Korean Peninsula and Przewalski's horse.

Seong HS, Kim NY, Kim DC, Hwang NH, Son DH, Shin JS, Lee JH, Chung WH, Choi JW.

Genes Genomics. 2019 Apr 2. doi: 10.1007/s13258-019-00795-w. [Epub ahead of print]


A 3D cell printed muscle construct with tissue-derived bioink for the treatment of volumetric muscle loss.

Choi YJ, Jun YJ, Kim DY, Yi HG, Chae SH, Kang J, Lee J, Gao G, Kong JS, Jang J, Chung WK, Rhie JW, Cho DW.

Biomaterials. 2019 Jun;206:160-169. doi: 10.1016/j.biomaterials.2019.03.036. Epub 2019 Mar 27.


Identification of a secondary RET mutation in a pediatric patient with relapsed acute myeloid leukemia leads to the diagnosis and treatment of asymptomatic metastatic medullary thyroid cancer in a parent: a case for sequencing the germline.

Pendrick DM, Oberg JA, Hsiao SJ, Chung WK, Koval C, Sireci A, Kuo JH, Satwani P, Glasser CL, Sulis ML, Mansukhani MM, Glade Bender JL.

Cold Spring Harb Mol Case Stud. 2019 Apr 1;5(2). pii: a003889. doi: 10.1101/mcs.a003889. Print 2019 Apr.


Evaluation of the cost and effectiveness of diverse recruitment methods for a genetic screening study.

Milo Rasouly H, Wynn J, Marasa M, Reingold R, Chatterjee D, Kapoor S, Piva S, Kil BH, Mu X, Alvarez M, Nestor J, Mehl K, Revah-Politi A, Lippa N, Ernst ME, Bier L, Espinal A, Haser B, Sinha A, Halim I, Fasel D, Cuneo N, Thompson JJ, Verbitsky M, Cohn EG, Goldman J, Marder K, Klitzman RL, Orjuela MA, So YS, Fedotov A, Crew KD, Kiryluk K, Appelbaum PS, Weng C, Siegel K, Gharavi AG, Chung WK.

Genet Med. 2019 Apr 1. doi: 10.1038/s41436-019-0497-y. [Epub ahead of print] Erratum in: Genet Med. 2019 May 1;:.


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