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Use of optical coherence tomography angiography in the diagnosis of small retina lesions in Von Hippel-Lindau disease.

Chun LY, Massamba N, Silas MR, Blair MP, Hariprasad SM, Skondra D.

Eye (Lond). 2020 Feb 10. doi: 10.1038/s41433-020-0792-5. [Epub ahead of print] No abstract available.


Rapid pathogen identification and antimicrobial susceptibility testing in in vitro endophthalmitis with matrix assisted laser desorption-ionization Time-of-Flight Mass Spectrometry and VITEK 2 without prior culture.

Chun LY, Dolle-Molle L, Bethel C, Dimitroyannis RC, Williams BL, Schechet SA, Hariprasad SM, Missiakas D, Schneewind O, Beavis KG, Skondra D.

PLoS One. 2019 Dec 30;14(12):e0227071. doi: 10.1371/journal.pone.0227071. eCollection 2019.


A Comprehensive Understanding of Dietary Effects on C. elegans Physiology.

Zhou JJ, Chun L, Liu JF.

Curr Med Sci. 2019 Oct;39(5):679-684. doi: 10.1007/s11596-019-2091-6. Epub 2019 Oct 14. Review.


Differences in macular capillary parameters between healthy black and white subjects with Optical Coherence Tomography Angiography (OCTA).

Chun LY, Silas MR, Dimitroyannis RC, Ho K, Skondra D.

PLoS One. 2019 Oct 9;14(10):e0223142. doi: 10.1371/journal.pone.0223142. eCollection 2019.


Breast cancer risk and breast screening for trans people: an integration of 3 systematic reviews.

Meggetto O, Peirson L, Yakubu M, Farid-Kapadia M, Costa-Fagbemi M, Baidoobonso S, Moffatt J, Chun L, Chiarelli AM, Muradali D.

CMAJ Open. 2019 Oct 1;7(3):E598-E609. doi: 10.9778/cmajo.20180028. Print 2019 Jul-Sep.


Clinically relevant model of pneumococcal pneumonia, ARDS, and nonpulmonary organ dysfunction in mice.

Gotts JE, Bernard O, Chun L, Croze RH, Ross JT, Nesseler N, Wu X, Abbott J, Fang X, Calfee CS, Matthay MA.

Am J Physiol Lung Cell Mol Physiol. 2019 Nov 1;317(5):L717-L736. doi: 10.1152/ajplung.00132.2019. Epub 2019 Sep 11.


GABA receptors differentially regulate life span and health span in C. elegans through distinct downstream mechanisms.

Yuan F, Zhou J, Xu L, Jia W, Chun L, Xu XZS, Liu J.

Am J Physiol Cell Physiol. 2019 Nov 1;317(5):C953-C963. doi: 10.1152/ajpcell.00072.2019. Epub 2019 Aug 21.


Endovascular Abdominal Aortic Aneurysm Repair: Does Anesthesia Type Matter?

Cheng M, Chen Q, Tran-McCaslin M, Chun L, Lew W, Patel K.

Ann Vasc Surg. 2019 Nov;61:284-290. doi: 10.1016/j.avsg.2019.04.031. Epub 2019 Jul 22.


Direct Synthesis of Upstanding Graphene/ZnO Nanowalls/Graphene Sandwich Heterojunction and Its Application for NO² Gas Sensor.

Xiong Y, Lingmin Y, Haining M, Yuan L, Chun L, Mingli Y, Hongbo D, Hui FX.

J Nanosci Nanotechnol. 2019 Dec 1;19(12):7947-7952. doi: 10.1166/jnn.2019.16856.


Ripretinib (DCC-2618) Is a Switch Control Kinase Inhibitor of a Broad Spectrum of Oncogenic and Drug-Resistant KIT and PDGFRA Variants.

Smith BD, Kaufman MD, Lu WP, Gupta A, Leary CB, Wise SC, Rutkoski TJ, Ahn YM, Al-Ani G, Bulfer SL, Caldwell TM, Chun L, Ensinger CL, Hood MM, McKinley A, Patt WC, Ruiz-Soto R, Su Y, Telikepalli H, Town A, Turner BA, Vogeti L, Vogeti S, Yates K, Janku F, Abdul Razak AR, Rosen O, Heinrich MC, Flynn DL.

Cancer Cell. 2019 May 13;35(5):738-751.e9. doi: 10.1016/j.ccell.2019.04.006.


Controllable stress elicits circuit-specific patterns of prefrontal plasticity in males, but not females.

Baratta MV, Gruene TM, Dolzani SD, Chun LE, Maier SF, Shansky RM.

Brain Struct Funct. 2019 Jun;224(5):1831-1843. doi: 10.1007/s00429-019-01875-z. Epub 2019 Apr 26.


Coordination between Prefrontal Cortex Clock Gene Expression and Corticosterone Contributes to Enhanced Conditioned Fear Extinction Recall.

Woodruff ER, Chun LE, Hinds LR, Varra NM, Tirado D, Morton SJ, McClung CA, Spencer RL.

eNeuro. 2018 Dec 21;5(6). pii: ENEURO.0455-18.2018. doi: 10.1523/ENEURO.0455-18.2018. eCollection 2018 Nov-Dec.


Perceived Value of the Daily Safety Briefing.

Pham JC, Laupola TMT, Figueira A, Bala J, Chun L.

J Healthc Manag. 2019 Jan-Feb;64(1):44-51. doi: 10.1097/JHM-D-17-00198.


Change of blue light hazard and circadian effect of LED backlight displayer with color temperature and age.

Chaopu Y, Wenqing F, Jiancheng T, Fan Y, Yanfeng L, Chun L.

Opt Express. 2018 Oct 15;26(21):27021-27032. doi: 10.1364/OE.26.027021.


Assessment of industry data on pulmonary and immunosuppressive effects of IQOS.

Moazed F, Chun L, Matthay MA, Calfee CS, Gotts J.

Tob Control. 2018 Nov;27(Suppl 1):s20-s25. doi: 10.1136/tobaccocontrol-2018-054296. Epub 2018 Aug 29.


Possible hepatotoxicity of IQOS.

Chun L, Moazed F, Matthay M, Calfee C, Gotts J.

Tob Control. 2018 Nov;27(Suppl 1):s39-s40. doi: 10.1136/tobaccocontrol-2018-054320. Epub 2018 Aug 21. No abstract available.


Human pulmonary endothelial cell permeability after exposure to LPS-stimulated leukocyte supernatants derived from patients with early sepsis.

Leligdowicz A, Chun LF, Jauregui A, Vessel K, Liu KD, Calfee CS, Matthay MA.

Am J Physiol Lung Cell Mol Physiol. 2018 Nov 1;315(5):L638-L644. doi: 10.1152/ajplung.00286.2018. Epub 2018 Jul 19.


Cigarette smoke exposure worsens acute lung injury in antibiotic-treated bacterial pneumonia in mice.

Gotts JE, Chun L, Abbott J, Fang X, Takasaka N, Nishimura SL, Springer ML, Schick SF, Calfee CS, Matthay MA.

Am J Physiol Lung Cell Mol Physiol. 2018 Jul 1;315(1):L25-L40. doi: 10.1152/ajplung.00405.2017. Epub 2018 Mar 15.


Structure-Activity Investigation of a G Protein-Biased Agonist Reveals Molecular Determinants for Biased Signaling of the D2 Dopamine Receptor.

Chun LS, Vekariya RH, Free RB, Li Y, Lin DT, Su P, Liu F, Namkung Y, Laporte SA, Moritz AE, Aubé J, Frankowski KJ, Sibley DR.

Front Synaptic Neurosci. 2018 Feb 21;10:2. doi: 10.3389/fnsyn.2018.00002. eCollection 2018.


Behavioural and neural sequelae of stressor exposure are not modulated by controllability in females.

Baratta MV, Leslie NR, Fallon IP, Dolzani SD, Chun LE, Tamalunas AM, Watkins LR, Maier SF.

Eur J Neurosci. 2018 Apr;47(8):959-967. doi: 10.1111/ejn.13833. Epub 2018 Feb 5.


Systemic administration of β-glucan of 200 kDa modulates melanoma microenvironment and suppresses metastatic cancer.

Zhang M, Chun L, Sandoval V, Graor H, Myers J, Nthale J, Rauhe P, Senders Z, Choong K, Huang AY, Kim J.

Oncoimmunology. 2017 Oct 30;7(2):e1387347. doi: 10.1080/2162402X.2017.1387347. eCollection 2018.


Glucocorticoid hormones are both a major circadian signal and major stress signal: How this shared signal contributes to a dynamic relationship between the circadian and stress systems.

Spencer RL, Chun LE, Hartsock MJ, Woodruff ER.

Front Neuroendocrinol. 2018 Apr;49:52-71. doi: 10.1016/j.yfrne.2017.12.005. Epub 2017 Dec 26. Review.


Adrenal-dependent and -independent stress-induced Per1 mRNA in hypothalamic paraventricular nucleus and prefrontal cortex of male and female rats.

Chun LE, Christensen J, Woodruff ER, Morton SJ, Hinds LR, Spencer RL.

Stress. 2018 Jan;21(1):69-83. doi: 10.1080/10253890.2017.1404571. Epub 2017 Nov 22.


Reply to "Letter to the Editor: Pulmonary toxicity of electronic cigarettes: more doubts than certainties".

Chun LF, Moazed F, Calfee CS, Matthay MA, Gotts JE.

Am J Physiol Lung Cell Mol Physiol. 2017 Nov 1;313(5):L966-L967. doi: 10.1152/ajplung.00428.2017. No abstract available.


The Selective Tie2 Inhibitor Rebastinib Blocks Recruitment and Function of Tie2Hi Macrophages in Breast Cancer and Pancreatic Neuroendocrine Tumors.

Harney AS, Karagiannis GS, Pignatelli J, Smith BD, Kadioglu E, Wise SC, Hood MM, Kaufman MD, Leary CB, Lu WP, Al-Ani G, Chen X, Entenberg D, Oktay MH, Wang Y, Chun L, De Palma M, Jones JG, Flynn DL, Condeelis JS.

Mol Cancer Ther. 2017 Nov;16(11):2486-2501. doi: 10.1158/1535-7163.MCT-17-0241. Epub 2017 Aug 24.


Analysis of c-Fos induction in response to social interaction in male and female Fisher 344 rats.

Perkins AE, Woodruff ER, Chun LE, Spencer RL, Varlinskaya E, Deak T.

Brain Res. 2017 Oct 1;1672:113-121. doi: 10.1016/j.brainres.2017.07.022. Epub 2017 Jul 29.


Protective effect of HDL on NADPH oxidase-derived super oxide anion mediates hypoxia-induced cardiomyocyte apoptosis.

Wen SY, Tamilselvi S, Shen CY, Day CH, Chun LC, Cheng LY, Ou HC, Chen RJ, Viswanadha VP, Kuo WW, Huang CY.

PLoS One. 2017 Jun 15;12(6):e0179492. doi: 10.1371/journal.pone.0179492. eCollection 2017.


Pulmonary toxicity of e-cigarettes.

Chun LF, Moazed F, Calfee CS, Matthay MA, Gotts JE.

Am J Physiol Lung Cell Mol Physiol. 2017 Aug 1;313(2):L193-L206. doi: 10.1152/ajplung.00071.2017. Epub 2017 May 18. Review.


High density lipoprotein (HDL) reverses palmitic acid induced energy metabolism imbalance by switching CD36 and GLUT4 signaling pathways in cardiomyocyte.

Wen SY, Velmurugan BK, Day CH, Shen CY, Chun LC, Tsai YC, Lin YM, Chen RJ, Kuo CH, Huang CY.

J Cell Physiol. 2017 Nov;232(11):3020-3029. doi: 10.1002/jcp.26007. Epub 2017 Jun 16.


Discovery of Selective Phosphodiesterase 1 Inhibitors with Memory Enhancing Properties.

Dyck B, Branstetter B, Gharbaoui T, Hudson AR, Breitenbucher JG, Gomez L, Botrous I, Marrone T, Barido R, Allerston CK, Cedervall EP, Xu R, Sridhar V, Barker R, Aertgeerts K, Schmelzer K, Neul D, Lee D, Massari ME, Andersen CB, Sebring K, Zhou X, Petroski R, Limberis J, Augustin M, Chun LE, Edwards TE, Peters M, Tabatabaei A.

J Med Chem. 2017 Apr 27;60(8):3472-3483. doi: 10.1021/acs.jmedchem.7b00302. Epub 2017 Apr 13.


Dynamic glucocorticoid-dependent regulation of Sgk1 expression in oligodendrocytes of adult male rat brain by acute stress and time of day.

Hinds LR, Chun LE, Woodruff ER, Christensen JA, Hartsock MJ, Spencer RL.

PLoS One. 2017 Apr 4;12(4):e0175075. doi: 10.1371/journal.pone.0175075. eCollection 2017.


The unique psychostimulant profile of (±)-modafinil: investigation of behavioral and neurochemical effects in mice.

Mereu M, Chun LE, Prisinzano TE, Newman AH, Katz JL, Tanda G.

Eur J Neurosci. 2017 Jan;45(1):167-174. doi: 10.1111/ejn.13376. Epub 2016 Sep 11.


The earliest herbivorous marine reptile and its remarkable jaw apparatus.

Chun L, Rieppel O, Long C, Fraser NC.

Sci Adv. 2016 May 6;2(5):e1501659. doi: 10.1126/sciadv.1501659. eCollection 2016 May.


Diurnal Corticosterone Presence and Phase Modulate Clock Gene Expression in the Male Rat Prefrontal Cortex.

Woodruff ER, Chun LE, Hinds LR, Spencer RL.

Endocrinology. 2016 Apr;157(4):1522-34. doi: 10.1210/en.2015-1884. Epub 2016 Feb 22.


Note: Magnetic targeting for enhancement of the activation efficiency of G protein-coupled receptor with a two-pair coil system.

Cao Q, Han X, Chun L, Liu J, Li L.

Rev Sci Instrum. 2016 Jan;87(1):016103. doi: 10.1063/1.4939732.


An initial investigation into the ecology of culturable aerobic postmortem bacteria.

Chun LP, Miguel MJ, Junkins EN, Forbes SL, Carter DO.

Sci Justice. 2015 Dec;55(6):394-401. doi: 10.1016/j.scijus.2015.07.003. Epub 2015 Aug 15.


Metabotropic GABA signalling modulates longevity in C. elegans.

Chun L, Gong J, Yuan F, Zhang B, Liu H, Zheng T, Yu T, Xu XZ, Liu J.

Nat Commun. 2015 Nov 5;6:8828. doi: 10.1038/ncomms9828.


Identification of a Natural Viral RNA Motif That Optimizes Sensing of Viral RNA by RIG-I.

Xu J, Mercado-López X, Grier JT, Kim WK, Chun LF, Irvine EB, Del Toro Duany Y, Kell A, Hur S, Gale M Jr, Raj A, López CB.

mBio. 2015 Oct 6;6(5):e01265-15. doi: 10.1128/mBio.01265-15.


Inhibition of RAF Isoforms and Active Dimers by LY3009120 Leads to Anti-tumor Activities in RAS or BRAF Mutant Cancers.

Peng SB, Henry JR, Kaufman MD, Lu WP, Smith BD, Vogeti S, Rutkoski TJ, Wise S, Chun L, Zhang Y, Van Horn RD, Yin T, Zhang X, Yadav V, Chen SH, Gong X, Ma X, Webster Y, Buchanan S, Mochalkin I, Huber L, Kays L, Donoho GP, Walgren J, McCann D, Patel P, Conti I, Plowman GD, Starling JJ, Flynn DL.

Cancer Cell. 2015 Sep 14;28(3):384-98. doi: 10.1016/j.ccell.2015.08.002. Epub 2015 Sep 3.


Altiratinib Inhibits Tumor Growth, Invasion, Angiogenesis, and Microenvironment-Mediated Drug Resistance via Balanced Inhibition of MET, TIE2, and VEGFR2.

Smith BD, Kaufman MD, Leary CB, Turner BA, Wise SC, Ahn YM, Booth RJ, Caldwell TM, Ensinger CL, Hood MM, Lu WP, Patt TW, Patt WC, Rutkoski TJ, Samarakoon T, Telikepalli H, Vogeti L, Vogeti S, Yates KM, Chun L, Stewart LJ, Clare M, Flynn DL.

Mol Cancer Ther. 2015 Sep;14(9):2023-34. doi: 10.1158/1535-7163.MCT-14-1105. Epub 2015 Aug 18.


Variations in Phase and Amplitude of Rhythmic Clock Gene Expression across Prefrontal Cortex, Hippocampus, Amygdala, and Hypothalamic Paraventricular and Suprachiasmatic Nuclei of Male and Female Rats.

Chun LE, Woodruff ER, Morton S, Hinds LR, Spencer RL.

J Biol Rhythms. 2015 Oct;30(5):417-36. doi: 10.1177/0748730415598608. Epub 2015 Aug 13.


Discovery of 1-(3,3-dimethylbutyl)-3-(2-fluoro-4-methyl-5-(7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl)phenyl)urea (LY3009120) as a pan-RAF inhibitor with minimal paradoxical activation and activity against BRAF or RAS mutant tumor cells.

Henry JR, Kaufman MD, Peng SB, Ahn YM, Caldwell TM, Vogeti L, Telikepalli H, Lu WP, Hood MM, Rutkoski TJ, Smith BD, Vogeti S, Miller D, Wise SC, Chun L, Zhang X, Zhang Y, Kays L, Hipskind PA, Wrobleski AD, Lobb KL, Clay JM, Cohen JD, Walgren JL, McCann D, Patel P, Clawson DK, Guo S, Manglicmot D, Groshong C, Logan C, Starling JJ, Flynn DL.

J Med Chem. 2015 May 28;58(10):4165-79. doi: 10.1021/acs.jmedchem.5b00067. Epub 2015 May 12.


RNAi Interrogation of Dietary Modulation of Development, Metabolism, Behavior, and Aging in C. elegans.

Xiao R, Chun L, Ronan EA, Friedman DI, Liu J, Xu XZ.

Cell Rep. 2015 May 19;11(7):1123-33. doi: 10.1016/j.celrep.2015.04.024. Epub 2015 May 7.


Oxidized high-density lipoprotein accelerates atherosclerosis progression by inducing the imbalance between treg and teff in LDLR knockout mice.

Ru D, Zhiqing H, Lin Z, Feng W, Feng Z, Jiayou Z, Yusheng R, Min F, Chun L, Zonggui W.

APMIS. 2015 May;123(5):410-21. doi: 10.1111/apm.12362.


Adrenal-dependent diurnal modulation of conditioned fear extinction learning.

Woodruff ER, Greenwood BN, Chun LE, Fardi S, Hinds LR, Spencer RL.

Behav Brain Res. 2015 Jun 1;286:249-55. doi: 10.1016/j.bbr.2015.03.006. Epub 2015 Mar 6.


(-)-Stepholidine is a potent pan-dopamine receptor antagonist of both G protein- and β-arrestin-mediated signaling.

Meade JA, Free RB, Miller NR, Chun LS, Doyle TB, Moritz AE, Conroy JL, Watts VJ, Sibley DR.

Psychopharmacology (Berl). 2015 Mar;232(5):917-30. doi: 10.1007/s00213-014-3726-8. Epub 2014 Sep 18.


Antitumor activity of miR-1280 in melanoma by regulation of Src.

Sun V, Zhou WB, Nosrati M, Majid S, Thummala S, de Semir D, Bezrookove V, de Feraudy S, Chun L, Schadendorf D, Debs R, Kashani-Sabet M, Dar AA.

Mol Ther. 2015 Jan;23(1):71-8. doi: 10.1038/mt.2014.176. Epub 2014 Sep 8.


Novel human D-amino acid oxidase inhibitors stabilize an active-site lid-open conformation.

Terry-Lorenzo RT, Chun LE, Brown SP, Heffernan ML, Fang QK, Orsini MA, Pollegioni L, Hardy LW, Spear KL, Large TH.

Biosci Rep. 2014 Aug 11;34(4). pii: e00133. doi: 10.1042/BSR20140071.


Preference for distinct functional conformations of the dopamine transporter alters the relationship between subjective effects of cocaine and stimulation of mesolimbic dopamine.

Kohut SJ, Hiranita T, Hong SK, Ebbs AL, Tronci V, Green J, Garcés-Ramírez L, Chun LE, Mereu M, Newman AH, Katz JL, Tanda G.

Biol Psychiatry. 2014 Nov 15;76(10):802-9. doi: 10.1016/j.biopsych.2014.03.031. Epub 2014 Apr 19.


Discovery and characterization of a G protein-biased agonist that inhibits β-arrestin recruitment to the D2 dopamine receptor.

Free RB, Chun LS, Moritz AE, Miller BN, Doyle TB, Conroy JL, Padron A, Meade JA, Xiao J, Hu X, Dulcey AE, Han Y, Duan L, Titus S, Bryant-Genevier M, Barnaeva E, Ferrer M, Javitch JA, Beuming T, Shi L, Southall NT, Marugan JJ, Sibley DR.

Mol Pharmacol. 2014 Jul;86(1):96-105. doi: 10.1124/mol.113.090563. Epub 2014 Apr 22.

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