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Items: 1 to 50 of 130

1.

Assessment of industry data on pulmonary and immunosuppressive effects of IQOS.

Moazed F, Chun L, Matthay MA, Calfee CS, Gotts J.

Tob Control. 2018 Aug 29. pii: tobaccocontrol-2018-054296. doi: 10.1136/tobaccocontrol-2018-054296. [Epub ahead of print]

2.

Possible hepatotoxicity of IQOS.

Chun L, Moazed F, Matthay M, Calfee C, Gotts J.

Tob Control. 2018 Aug 21. pii: tobaccocontrol-2018-054320. doi: 10.1136/tobaccocontrol-2018-054320. [Epub ahead of print] No abstract available.

PMID:
30131373
3.

Human pulmonary endothelial cell permeability after exposure to LPS-stimulated leukocyte supernatants derived from patients with early sepsis.

Leligdowicz A, Chun LF, Jauregui A, Vessel K, Liu KD, Calfee CS, Matthay MA.

Am J Physiol Lung Cell Mol Physiol. 2018 Jul 19. doi: 10.1152/ajplung.00286.2018. [Epub ahead of print]

PMID:
30024307
4.

Cigarette smoke exposure worsens acute lung injury in antibiotic-treated bacterial pneumonia in mice.

Gotts JE, Chun L, Abbott J, Fang X, Takasaka N, Nishimura SL, Springer ML, Schick SF, Calfee CS, Matthay MA.

Am J Physiol Lung Cell Mol Physiol. 2018 Jul 1;315(1):L25-L40. doi: 10.1152/ajplung.00405.2017. Epub 2018 Mar 15.

5.

Structure-Activity Investigation of a G Protein-Biased Agonist Reveals Molecular Determinants for Biased Signaling of the D2 Dopamine Receptor.

Chun LS, Vekariya RH, Free RB, Li Y, Lin DT, Su P, Liu F, Namkung Y, Laporte SA, Moritz AE, Aubé J, Frankowski KJ, Sibley DR.

Front Synaptic Neurosci. 2018 Feb 21;10:2. doi: 10.3389/fnsyn.2018.00002. eCollection 2018.

6.

Behavioural and neural sequelae of stressor exposure are not modulated by controllability in females.

Baratta MV, Leslie NR, Fallon IP, Dolzani SD, Chun LE, Tamalunas AM, Watkins LR, Maier SF.

Eur J Neurosci. 2018 Apr;47(8):959-967. doi: 10.1111/ejn.13833. Epub 2018 Feb 5.

PMID:
29359831
7.

Systemic administration of β-glucan of 200 kDa modulates melanoma microenvironment and suppresses metastatic cancer.

Zhang M, Chun L, Sandoval V, Graor H, Myers J, Nthale J, Rauhe P, Senders Z, Choong K, Huang AY, Kim J.

Oncoimmunology. 2017 Oct 30;7(2):e1387347. doi: 10.1080/2162402X.2017.1387347. eCollection 2018.

PMID:
29308312
8.

Glucocorticoid hormones are both a major circadian signal and major stress signal: How this shared signal contributes to a dynamic relationship between the circadian and stress systems.

Spencer RL, Chun LE, Hartsock MJ, Woodruff ER.

Front Neuroendocrinol. 2018 Apr;49:52-71. doi: 10.1016/j.yfrne.2017.12.005. Epub 2017 Dec 26. Review.

PMID:
29288075
9.

Adrenal-dependent and -independent stress-induced Per1 mRNA in hypothalamic paraventricular nucleus and prefrontal cortex of male and female rats.

Chun LE, Christensen J, Woodruff ER, Morton SJ, Hinds LR, Spencer RL.

Stress. 2018 Jan;21(1):69-83. doi: 10.1080/10253890.2017.1404571. Epub 2017 Nov 22.

PMID:
29165002
10.

Reply to "Letter to the Editor: Pulmonary toxicity of electronic cigarettes: more doubts than certainties".

Chun LF, Moazed F, Calfee CS, Matthay MA, Gotts JE.

Am J Physiol Lung Cell Mol Physiol. 2017 Nov 1;313(5):L966-L967. doi: 10.1152/ajplung.00428.2017. No abstract available.

PMID:
29109110
11.

The Selective Tie2 Inhibitor Rebastinib Blocks Recruitment and Function of Tie2Hi Macrophages in Breast Cancer and Pancreatic Neuroendocrine Tumors.

Harney AS, Karagiannis GS, Pignatelli J, Smith BD, Kadioglu E, Wise SC, Hood MM, Kaufman MD, Leary CB, Lu WP, Al-Ani G, Chen X, Entenberg D, Oktay MH, Wang Y, Chun L, De Palma M, Jones JG, Flynn DL, Condeelis JS.

Mol Cancer Ther. 2017 Nov;16(11):2486-2501. doi: 10.1158/1535-7163.MCT-17-0241. Epub 2017 Aug 24.

PMID:
28838996
12.

Analysis of c-Fos induction in response to social interaction in male and female Fisher 344 rats.

Perkins AE, Woodruff ER, Chun LE, Spencer RL, Varlinskaya E, Deak T.

Brain Res. 2017 Oct 1;1672:113-121. doi: 10.1016/j.brainres.2017.07.022. Epub 2017 Jul 29.

PMID:
28764933
13.

Protective effect of HDL on NADPH oxidase-derived super oxide anion mediates hypoxia-induced cardiomyocyte apoptosis.

Wen SY, Tamilselvi S, Shen CY, Day CH, Chun LC, Cheng LY, Ou HC, Chen RJ, Viswanadha VP, Kuo WW, Huang CY.

PLoS One. 2017 Jun 15;12(6):e0179492. doi: 10.1371/journal.pone.0179492. eCollection 2017.

14.

Pulmonary toxicity of e-cigarettes.

Chun LF, Moazed F, Calfee CS, Matthay MA, Gotts JE.

Am J Physiol Lung Cell Mol Physiol. 2017 Aug 1;313(2):L193-L206. doi: 10.1152/ajplung.00071.2017. Epub 2017 May 18. Review.

15.

High density lipoprotein (HDL) reverses palmitic acid induced energy metabolism imbalance by switching CD36 and GLUT4 signaling pathways in cardiomyocyte.

Wen SY, Velmurugan BK, Day CH, Shen CY, Chun LC, Tsai YC, Lin YM, Chen RJ, Kuo CH, Huang CY.

J Cell Physiol. 2017 Nov;232(11):3020-3029. doi: 10.1002/jcp.26007. Epub 2017 Jun 16.

PMID:
28500736
16.

Discovery of Selective Phosphodiesterase 1 Inhibitors with Memory Enhancing Properties.

Dyck B, Branstetter B, Gharbaoui T, Hudson AR, Breitenbucher JG, Gomez L, Botrous I, Marrone T, Barido R, Allerston CK, Cedervall EP, Xu R, Sridhar V, Barker R, Aertgeerts K, Schmelzer K, Neul D, Lee D, Massari ME, Andersen CB, Sebring K, Zhou X, Petroski R, Limberis J, Augustin M, Chun LE, Edwards TE, Peters M, Tabatabaei A.

J Med Chem. 2017 Apr 27;60(8):3472-3483. doi: 10.1021/acs.jmedchem.7b00302. Epub 2017 Apr 13.

PMID:
28406621
17.

Dynamic glucocorticoid-dependent regulation of Sgk1 expression in oligodendrocytes of adult male rat brain by acute stress and time of day.

Hinds LR, Chun LE, Woodruff ER, Christensen JA, Hartsock MJ, Spencer RL.

PLoS One. 2017 Apr 4;12(4):e0175075. doi: 10.1371/journal.pone.0175075. eCollection 2017.

18.

The unique psychostimulant profile of (±)-modafinil: investigation of behavioral and neurochemical effects in mice.

Mereu M, Chun LE, Prisinzano TE, Newman AH, Katz JL, Tanda G.

Eur J Neurosci. 2017 Jan;45(1):167-174. doi: 10.1111/ejn.13376. Epub 2016 Sep 11.

19.

The earliest herbivorous marine reptile and its remarkable jaw apparatus.

Chun L, Rieppel O, Long C, Fraser NC.

Sci Adv. 2016 May 6;2(5):e1501659. doi: 10.1126/sciadv.1501659. eCollection 2016 May.

20.

Diurnal Corticosterone Presence and Phase Modulate Clock Gene Expression in the Male Rat Prefrontal Cortex.

Woodruff ER, Chun LE, Hinds LR, Spencer RL.

Endocrinology. 2016 Apr;157(4):1522-34. doi: 10.1210/en.2015-1884. Epub 2016 Feb 22.

21.

Note: Magnetic targeting for enhancement of the activation efficiency of G protein-coupled receptor with a two-pair coil system.

Cao Q, Han X, Chun L, Liu J, Li L.

Rev Sci Instrum. 2016 Jan;87(1):016103. doi: 10.1063/1.4939732.

PMID:
26827364
22.

An initial investigation into the ecology of culturable aerobic postmortem bacteria.

Chun LP, Miguel MJ, Junkins EN, Forbes SL, Carter DO.

Sci Justice. 2015 Dec;55(6):394-401. doi: 10.1016/j.scijus.2015.07.003. Epub 2015 Aug 15.

PMID:
26654073
23.

Metabotropic GABA signalling modulates longevity in C. elegans.

Chun L, Gong J, Yuan F, Zhang B, Liu H, Zheng T, Yu T, Xu XZ, Liu J.

Nat Commun. 2015 Nov 5;6:8828. doi: 10.1038/ncomms9828.

24.

Identification of a Natural Viral RNA Motif That Optimizes Sensing of Viral RNA by RIG-I.

Xu J, Mercado-López X, Grier JT, Kim WK, Chun LF, Irvine EB, Del Toro Duany Y, Kell A, Hur S, Gale M Jr, Raj A, López CB.

MBio. 2015 Oct 6;6(5):e01265-15. doi: 10.1128/mBio.01265-15.

25.

Inhibition of RAF Isoforms and Active Dimers by LY3009120 Leads to Anti-tumor Activities in RAS or BRAF Mutant Cancers.

Peng SB, Henry JR, Kaufman MD, Lu WP, Smith BD, Vogeti S, Rutkoski TJ, Wise S, Chun L, Zhang Y, Van Horn RD, Yin T, Zhang X, Yadav V, Chen SH, Gong X, Ma X, Webster Y, Buchanan S, Mochalkin I, Huber L, Kays L, Donoho GP, Walgren J, McCann D, Patel P, Conti I, Plowman GD, Starling JJ, Flynn DL.

Cancer Cell. 2015 Sep 14;28(3):384-98. doi: 10.1016/j.ccell.2015.08.002. Epub 2015 Sep 3.

26.

Altiratinib Inhibits Tumor Growth, Invasion, Angiogenesis, and Microenvironment-Mediated Drug Resistance via Balanced Inhibition of MET, TIE2, and VEGFR2.

Smith BD, Kaufman MD, Leary CB, Turner BA, Wise SC, Ahn YM, Booth RJ, Caldwell TM, Ensinger CL, Hood MM, Lu WP, Patt TW, Patt WC, Rutkoski TJ, Samarakoon T, Telikepalli H, Vogeti L, Vogeti S, Yates KM, Chun L, Stewart LJ, Clare M, Flynn DL.

Mol Cancer Ther. 2015 Sep;14(9):2023-34. doi: 10.1158/1535-7163.MCT-14-1105. Epub 2015 Aug 18.

27.

Variations in Phase and Amplitude of Rhythmic Clock Gene Expression across Prefrontal Cortex, Hippocampus, Amygdala, and Hypothalamic Paraventricular and Suprachiasmatic Nuclei of Male and Female Rats.

Chun LE, Woodruff ER, Morton S, Hinds LR, Spencer RL.

J Biol Rhythms. 2015 Oct;30(5):417-36. doi: 10.1177/0748730415598608. Epub 2015 Aug 13.

PMID:
26271538
28.

Discovery of 1-(3,3-dimethylbutyl)-3-(2-fluoro-4-methyl-5-(7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl)phenyl)urea (LY3009120) as a pan-RAF inhibitor with minimal paradoxical activation and activity against BRAF or RAS mutant tumor cells.

Henry JR, Kaufman MD, Peng SB, Ahn YM, Caldwell TM, Vogeti L, Telikepalli H, Lu WP, Hood MM, Rutkoski TJ, Smith BD, Vogeti S, Miller D, Wise SC, Chun L, Zhang X, Zhang Y, Kays L, Hipskind PA, Wrobleski AD, Lobb KL, Clay JM, Cohen JD, Walgren JL, McCann D, Patel P, Clawson DK, Guo S, Manglicmot D, Groshong C, Logan C, Starling JJ, Flynn DL.

J Med Chem. 2015 May 28;58(10):4165-79. doi: 10.1021/acs.jmedchem.5b00067. Epub 2015 May 12.

PMID:
25965804
29.

RNAi Interrogation of Dietary Modulation of Development, Metabolism, Behavior, and Aging in C. elegans.

Xiao R, Chun L, Ronan EA, Friedman DI, Liu J, Xu XZ.

Cell Rep. 2015 May 19;11(7):1123-33. doi: 10.1016/j.celrep.2015.04.024. Epub 2015 May 7.

30.

Oxidized high-density lipoprotein accelerates atherosclerosis progression by inducing the imbalance between treg and teff in LDLR knockout mice.

Ru D, Zhiqing H, Lin Z, Feng W, Feng Z, Jiayou Z, Yusheng R, Min F, Chun L, Zonggui W.

APMIS. 2015 May;123(5):410-21. doi: 10.1111/apm.12362.

PMID:
25912129
31.

Adrenal-dependent diurnal modulation of conditioned fear extinction learning.

Woodruff ER, Greenwood BN, Chun LE, Fardi S, Hinds LR, Spencer RL.

Behav Brain Res. 2015 Jun 1;286:249-55. doi: 10.1016/j.bbr.2015.03.006. Epub 2015 Mar 6.

32.

(-)-Stepholidine is a potent pan-dopamine receptor antagonist of both G protein- and β-arrestin-mediated signaling.

Meade JA, Free RB, Miller NR, Chun LS, Doyle TB, Moritz AE, Conroy JL, Watts VJ, Sibley DR.

Psychopharmacology (Berl). 2015 Mar;232(5):917-30. doi: 10.1007/s00213-014-3726-8. Epub 2014 Sep 18.

33.

Antitumor activity of miR-1280 in melanoma by regulation of Src.

Sun V, Zhou WB, Nosrati M, Majid S, Thummala S, de Semir D, Bezrookove V, de Feraudy S, Chun L, Schadendorf D, Debs R, Kashani-Sabet M, Dar AA.

Mol Ther. 2015 Jan;23(1):71-8. doi: 10.1038/mt.2014.176. Epub 2014 Sep 8.

34.

Novel human D-amino acid oxidase inhibitors stabilize an active-site lid-open conformation.

Terry-Lorenzo RT, Chun LE, Brown SP, Heffernan ML, Fang QK, Orsini MA, Pollegioni L, Hardy LW, Spear KL, Large TH.

Biosci Rep. 2014 Aug 11;34(4). pii: e00133. doi: 10.1042/BSR20140071.

35.

Preference for distinct functional conformations of the dopamine transporter alters the relationship between subjective effects of cocaine and stimulation of mesolimbic dopamine.

Kohut SJ, Hiranita T, Hong SK, Ebbs AL, Tronci V, Green J, Garcés-Ramírez L, Chun LE, Mereu M, Newman AH, Katz JL, Tanda G.

Biol Psychiatry. 2014 Nov 15;76(10):802-9. doi: 10.1016/j.biopsych.2014.03.031. Epub 2014 Apr 19.

36.

Discovery and characterization of a G protein-biased agonist that inhibits β-arrestin recruitment to the D2 dopamine receptor.

Free RB, Chun LS, Moritz AE, Miller BN, Doyle TB, Conroy JL, Padron A, Meade JA, Xiao J, Hu X, Dulcey AE, Han Y, Duan L, Titus S, Bryant-Genevier M, Barnaeva E, Ferrer M, Javitch JA, Beuming T, Shi L, Southall NT, Marugan JJ, Sibley DR.

Mol Pharmacol. 2014 Jul;86(1):96-105. doi: 10.1124/mol.113.090563. Epub 2014 Apr 22.

37.

Screening carotid artery duplex in patients undergoing cardiac surgery.

Chun LJ, Tsai J, Tam M, Prema J, Chen LH, Patel KK.

Ann Vasc Surg. 2014 Jul;28(5):1178-85. doi: 10.1016/j.avsg.2013.07.025. Epub 2013 Nov 5.

PMID:
24211602
38.

Efficacy of contemporary medical management for asymptomatic carotid artery stenosis.

Chang J, Ahn JE, Landsman N, Rhee K, Chun L, Patel KK.

Am Surg. 2013 Oct;79(10):987-91.

PMID:
24160784
39.

Cocaine-induced endocannabinoid release modulates behavioral and neurochemical sensitization in mice.

Mereu M, Tronci V, Chun LE, Thomas AM, Green JL, Katz JL, Tanda G.

Addict Biol. 2015 Jan;20(1):91-103. doi: 10.1111/adb.12080. Epub 2013 Aug 4.

40.

D1-D2 dopamine receptor synergy promotes calcium signaling via multiple mechanisms.

Chun LS, Free RB, Doyle TB, Huang XP, Rankin ML, Sibley DR.

Mol Pharmacol. 2013 Aug;84(2):190-200. doi: 10.1124/mol.113.085175. Epub 2013 May 16.

41.

Relations between stimulation of mesolimbic dopamine and place conditioning in rats produced by cocaine or drugs that are tolerant to dopamine transporter conformational change.

Tanda G, Li SM, Mereu M, Thomas AM, Ebbs AL, Chun LE, Tronci V, Green JL, Zou MF, Kopajtic TA, Newman AH, Katz JL.

Psychopharmacology (Berl). 2013 Sep;229(2):307-21. doi: 10.1007/s00213-013-3109-6. Epub 2013 Apr 24.

42.

Wenckebach periodicity at rest that normalizes with tachycardia in a family with a NKX2.5 mutation.

Guntheroth W, Chun L, Patton KK, Matsushita MM, Page RL, Raskind WH.

Am J Cardiol. 2012 Dec 1;110(11):1646-50. doi: 10.1016/j.amjcard.2012.07.033. Epub 2012 Aug 22.

PMID:
22920929
43.

Mass segmentation using a combined method for cancer detection.

Liu J, Chen J, Liu X, Chun L, Tang J, Deng Y.

BMC Syst Biol. 2011;5 Suppl 3:S6. doi: 10.1186/1752-0509-5-S3-S6. Epub 2011 Dec 23.

44.

Medical students learn from afar.

Chun L.

Md Med. 2012;13(1):33-4. No abstract available.

PMID:
22787935
45.

GABAB receptor subunit GB1 at the cell surface independently activates ERK1/2 through IGF-1R transactivation.

Baloucoune GA, Chun L, Zhang W, Xu C, Huang S, Sun Q, Wang Y, Tu H, Liu J.

PLoS One. 2012;7(6):e39698. doi: 10.1371/journal.pone.0039698. Epub 2012 Jun 28.

46.

Radiofrequency treatment for fecal incontinence: is it effective long-term?

Abbas MA, Tam MS, Chun LJ.

Dis Colon Rectum. 2012 May;55(5):605-10. doi: 10.1097/DCR.0b013e3182415406.

PMID:
22513440
47.

A robust detail preserving anisotropic diffusion for speckle reduction in ultrasound images.

Liu X, Liu J, Xu X, Chun L, Tang J, Deng Y.

BMC Genomics. 2011 Dec 23;12 Suppl 5:S14. doi: 10.1186/1471-2164-12-S5-S14. Epub 2011 Dec 23.

48.

Mechanism of inhibition for N6022, a first-in-class drug targeting S-nitrosoglutathione reductase.

Green LS, Chun LE, Patton AK, Sun X, Rosenthal GJ, Richards JP.

Biochemistry. 2012 Mar 13;51(10):2157-68. doi: 10.1021/bi201785u. Epub 2012 Feb 28.

PMID:
22335564
49.

Structure and ligand recognition of class C GPCRs.

Chun L, Zhang WH, Liu JF.

Acta Pharmacol Sin. 2012 Mar;33(3):312-23. doi: 10.1038/aps.2011.186. Epub 2012 Jan 30. Review.

50.

Defunctioning loop ileostomy for pelvic anastomoses: predictors of morbidity and nonclosure.

Chun LJ, Haigh PI, Tam MS, Abbas MA.

Dis Colon Rectum. 2012 Feb;55(2):167-74. doi: 10.1097/DCR.0b013e31823a9761.

PMID:
22228160

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