Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 57

1.

Mouse GTSF1 is an essential factor for secondary piRNA biogenesis.

Yoshimura T, Watanabe T, Kuramochi-Miyagawa S, Takemoto N, Shiromoto Y, Kudo A, Kanai-Azuma M, Tashiro F, Miyazaki S, Katanaya A, Chuma S, Miyazaki JI.

EMBO Rep. 2018 Apr;19(4). pii: e42054. doi: 10.15252/embr.201642054. Epub 2018 Feb 7.

PMID:
29437694
2.

PARI Regulates Stalled Replication Fork Processing To Maintain Genome Stability upon Replication Stress in Mice.

Mochizuki AL, Katanaya A, Hayashi E, Hosokawa M, Moribe E, Motegi A, Ishiai M, Takata M, Kondoh G, Watanabe H, Nakatsuji N, Chuma S.

Mol Cell Biol. 2017 Nov 13;37(23). pii: e00117-17. doi: 10.1128/MCB.00117-17. Print 2017 Dec 1.

3.

Roles of MIWI, MILI and PLD6 in small RNA regulation in mouse growing oocytes.

Kabayama Y, Toh H, Katanaya A, Sakurai T, Chuma S, Kuramochi-Miyagawa S, Saga Y, Nakano T, Sasaki H.

Nucleic Acids Res. 2017 May 19;45(9):5387-5398. doi: 10.1093/nar/gkx027.

4.

Mouse D1Pas1, a DEAD-box RNA helicase, is required for the completion of first meiotic prophase in male germ cells.

Inoue H, Ogonuki N, Hirose M, Hatanaka Y, Matoba S, Chuma S, Kobayashi K, Wakana S, Noguchi J, Inoue K, Tanemura K, Ogura A.

Biochem Biophys Res Commun. 2016 Sep 16;478(2):592-8. doi: 10.1016/j.bbrc.2016.07.109. Epub 2016 Jul 27.

PMID:
27473657
5.

Phase I/II trial of everolimus in combination with bortezomib and rituximab (RVR) in relapsed/refractory Waldenstrom macroglobulinemia.

Ghobrial IM, Redd R, Armand P, Banwait R, Boswell E, Chuma S, Huynh D, Sacco A, Roccaro AM, Perilla-Glen A, Noonan K, MacNabb M, Leblebjian H, Warren D, Henrick P, Castillo JJ, Richardson PG, Matous J, Weller E, Treon SP.

Leukemia. 2015 Dec;29(12):2338-46. doi: 10.1038/leu.2015.164. Epub 2015 Jul 3.

PMID:
26139427
6.

HSP90α plays an important role in piRNA biogenesis and retrotransposon repression in mouse.

Ichiyanagi T, Ichiyanagi K, Ogawa A, Kuramochi-Miyagawa S, Nakano T, Chuma S, Sasaki H, Udono H.

Nucleic Acids Res. 2014 Oct 29;42(19):11903-11. doi: 10.1093/nar/gku881. Epub 2014 Sep 27.

7.

LINE-1 of evidence for fetal oocyte attrition by retrotransposon.

Chuma S.

Dev Cell. 2014 Jun 9;29(5):501-502. doi: 10.1016/j.devcel.2014.05.017.

8.

Carfilzomib, rituximab, and dexamethasone (CaRD) treatment offers a neuropathy-sparing approach for treating Waldenström's macroglobulinemia.

Treon SP, Tripsas CK, Meid K, Kanan S, Sheehy P, Chuma S, Xu L, Cao Y, Yang G, Liu X, Patterson CJ, Warren D, Hunter ZR, Turnbull B, Ghobrial IM, Castillo JJ.

Blood. 2014 Jul 24;124(4):503-10. doi: 10.1182/blood-2014-03-566273. Epub 2014 May 23.

9.

Long-term results of the phase II trial of the oral mTOR inhibitor everolimus (RAD001) in relapsed or refractory Waldenstrom Macroglobulinemia.

Ghobrial IM, Witzig TE, Gertz M, LaPlant B, Hayman S, Camoriano J, Lacy M, Bergsagel PL, Chuma S, DeAngelo D, Treon SP.

Am J Hematol. 2014 Mar;89(3):237-42.

10.

Tudor domain containing 12 (TDRD12) is essential for secondary PIWI interacting RNA biogenesis in mice.

Pandey RR, Tokuzawa Y, Yang Z, Hayashi E, Ichisaka T, Kajita S, Asano Y, Kunieda T, Sachidanandam R, Chuma S, Yamanaka S, Pillai RS.

Proc Natl Acad Sci U S A. 2013 Oct 8;110(41):16492-7. doi: 10.1073/pnas.1316316110. Epub 2013 Sep 25.

11.

The nuage mediates retrotransposon silencing in mouse primordial ovarian follicles.

Lim AK, Lorthongpanich C, Chew TG, Tan CW, Shue YT, Balu S, Gounko N, Kuramochi-Miyagawa S, Matzuk MM, Chuma S, Messerschmidt DM, Solter D, Knowles BB.

Development. 2013 Sep;140(18):3819-25. doi: 10.1242/dev.099184. Epub 2013 Aug 7.

12.

GPAT2, a mitochondrial outer membrane protein, in piRNA biogenesis in germline stem cells.

Shiromoto Y, Kuramochi-Miyagawa S, Daiba A, Chuma S, Katanaya A, Katsumata A, Nishimura K, Ohtaka M, Nakanishi M, Nakamura T, Yoshinaga K, Asada N, Nakamura S, Yasunaga T, Kojima-Kita K, Itou D, Kimura T, Nakano T.

RNA. 2013 Jun;19(6):803-10. doi: 10.1261/rna.038521.113. Epub 2013 Apr 23.

13.

Results of a phase 2 trial of the single-agent histone deacetylase inhibitor panobinostat in patients with relapsed/refractory Waldenström macroglobulinemia.

Ghobrial IM, Campigotto F, Murphy TJ, Boswell EN, Banwait R, Azab F, Chuma S, Kunsman J, Donovan A, Masood F, Warren D, Rodig S, Anderson KC, Richardson PG, Weller E, Matous J.

Blood. 2013 Feb 21;121(8):1296-303. doi: 10.1182/blood-2012-06-439307. Epub 2013 Jan 3.

14.

piRNA and spermatogenesis in mice.

Chuma S, Nakano T.

Philos Trans R Soc Lond B Biol Sci. 2013 Jan 5;368(1609):20110338. doi: 10.1098/rstb.2011.0338. Review.

15.

A role for Fkbp6 and the chaperone machinery in piRNA amplification and transposon silencing.

Xiol J, Cora E, Koglgruber R, Chuma S, Subramanian S, Hosokawa M, Reuter M, Yang Z, Berninger P, Palencia A, Benes V, Penninger J, Sachidanandam R, Pillai RS.

Mol Cell. 2012 Sep 28;47(6):970-9. doi: 10.1016/j.molcel.2012.07.019. Epub 2012 Aug 16.

16.

piRNAs and their involvement in male germline development in mice.

Pillai RS, Chuma S.

Dev Growth Differ. 2012 Jan;54(1):78-92. doi: 10.1111/j.1440-169X.2011.01320.x. Epub 2012 Jan 6. Review.

PMID:
22221002
17.

Human PSF concentrates DNA and stimulates duplex capture in DMC1-mediated homologous pairing.

Morozumi Y, Ino R, Takaku M, Hosokawa M, Chuma S, Kurumizaka H.

Nucleic Acids Res. 2012 Apr;40(7):3031-41. doi: 10.1093/nar/gkr1229. Epub 2011 Dec 9.

18.

Miwi catalysis is required for piRNA amplification-independent LINE1 transposon silencing.

Reuter M, Berninger P, Chuma S, Shah H, Hosokawa M, Funaya C, Antony C, Sachidanandam R, Pillai RS.

Nature. 2011 Nov 27;480(7376):264-7. doi: 10.1038/nature10672.

PMID:
22121019
19.

Tudor domain containing 7 (Tdrd7) is essential for dynamic ribonucleoprotein (RNP) remodeling of chromatoid bodies during spermatogenesis.

Tanaka T, Hosokawa M, Vagin VV, Reuter M, Hayashi E, Mochizuki AL, Kitamura K, Yamanaka H, Kondoh G, Okawa K, Kuramochi-Miyagawa S, Nakano T, Sachidanandam R, Hannon GJ, Pillai RS, Nakatsuji N, Chuma S.

Proc Natl Acad Sci U S A. 2011 Jun 28;108(26):10579-84. doi: 10.1073/pnas.1015447108. Epub 2011 Jun 13.

20.

MITOPLD is a mitochondrial protein essential for nuage formation and piRNA biogenesis in the mouse germline.

Watanabe T, Chuma S, Yamamoto Y, Kuramochi-Miyagawa S, Totoki Y, Toyoda A, Hoki Y, Fujiyama A, Shibata T, Sado T, Noce T, Nakano T, Nakatsuji N, Lin H, Sasaki H.

Dev Cell. 2011 Mar 15;20(3):364-75. doi: 10.1016/j.devcel.2011.01.005.

21.

TDRD5 is required for retrotransposon silencing, chromatoid body assembly, and spermiogenesis in mice.

Yabuta Y, Ohta H, Abe T, Kurimoto K, Chuma S, Saitou M.

J Cell Biol. 2011 Mar 7;192(5):781-95. doi: 10.1083/jcb.201009043.

22.

Weekly bortezomib in combination with temsirolimus in relapsed or relapsed and refractory multiple myeloma: a multicentre, phase 1/2, open-label, dose-escalation study.

Ghobrial IM, Weller E, Vij R, Munshi NC, Banwait R, Bagshaw M, Schlossman R, Leduc R, Chuma S, Kunsman J, Laubach J, Jakubowiak AJ, Maiso P, Roccaro A, Armand P, Dollard A, Warren D, Harris B, Poon T, Sam A, Rodig S, Anderson KC, Richardson PG.

Lancet Oncol. 2011 Mar;12(3):263-72. doi: 10.1016/S1470-2045(11)70028-6. Epub 2011 Feb 21.

PMID:
21345726
23.

Phase II trial of weekly bortezomib in combination with rituximab in untreated patients with Waldenström Macroglobulinemia.

Ghobrial IM, Xie W, Padmanabhan S, Badros A, Rourke M, Leduc R, Chuma S, Kunsman J, Warren D, Poon T, Harris B, Sam A, Anderson KC, Richardson PG, Treon SP, Weller E, Matous J.

Am J Hematol. 2010 Sep;85(9):670-4. doi: 10.1002/ajh.21788.

24.

MVH in piRNA processing and gene silencing of retrotransposons.

Kuramochi-Miyagawa S, Watanabe T, Gotoh K, Takamatsu K, Chuma S, Kojima-Kita K, Shiromoto Y, Asada N, Toyoda A, Fujiyama A, Totoki Y, Shibata T, Kimura T, Nakatsuji N, Noce T, Sasaki H, Nakano T.

Genes Dev. 2010 May;24(9):887-92. doi: 10.1101/gad.1902110.

25.

Phase II trial of the oral mammalian target of rapamycin inhibitor everolimus in relapsed or refractory Waldenstrom macroglobulinemia.

Ghobrial IM, Gertz M, Laplant B, Camoriano J, Hayman S, Lacy M, Chuma S, Harris B, Leduc R, Rourke M, Ansell SM, Deangelo D, Dispenzieri A, Bergsagel L, Reeder C, Anderson KC, Richardson PG, Treon SP, Witzig TE.

J Clin Oncol. 2010 Mar 10;28(8):1408-14. doi: 10.1200/JCO.2009.24.0994. Epub 2010 Feb 8.

26.

Phase II trial of weekly bortezomib in combination with rituximab in relapsed or relapsed and refractory Waldenstrom macroglobulinemia.

Ghobrial IM, Hong F, Padmanabhan S, Badros A, Rourke M, Leduc R, Chuma S, Kunsman J, Warren D, Harris B, Sam A, Anderson KC, Richardson PG, Treon SP, Weller E, Matous J.

J Clin Oncol. 2010 Mar 10;28(8):1422-8. doi: 10.1200/JCO.2009.25.3237. Epub 2010 Feb 8.

27.

Clinical and translational studies of a phase II trial of the novel oral Akt inhibitor perifosine in relapsed or relapsed/refractory Waldenstrom's macroglobulinemia.

Ghobrial IM, Roccaro A, Hong F, Weller E, Rubin N, Leduc R, Rourke M, Chuma S, Sacco A, Jia X, Azab F, Azab AK, Rodig S, Warren D, Harris B, Varticovski L, Sportelli P, Leleu X, Anderson KC, Richardson PG.

Clin Cancer Res. 2010 Feb 1;16(3):1033-41. doi: 10.1158/1078-0432.CCR-09-1837. Epub 2010 Jan 26.

28.

The TDRD9-MIWI2 complex is essential for piRNA-mediated retrotransposon silencing in the mouse male germline.

Shoji M, Tanaka T, Hosokawa M, Reuter M, Stark A, Kato Y, Kondoh G, Okawa K, Chujo T, Suzuki T, Hata K, Martin SL, Noce T, Kuramochi-Miyagawa S, Nakano T, Sasaki H, Pillai RS, Nakatsuji N, Chuma S.

Dev Cell. 2009 Dec;17(6):775-87. doi: 10.1016/j.devcel.2009.10.012.

29.

Retrotransposon silencing by piRNAs: ping-pong players mark their sub-cellular boundaries.

Chuma S, Pillai RS.

PLoS Genet. 2009 Dec;5(12):e1000770. doi: 10.1371/journal.pgen.1000770. Epub 2009 Dec 11. No abstract available.

30.

Phenotypic plasticity of mouse spermatogonial stem cells.

Morimoto H, Kanatsu-Shinohara M, Takashima S, Chuma S, Nakatsuji N, Takehashi M, Shinohara T.

PLoS One. 2009 Nov 19;4(11):e7909. doi: 10.1371/journal.pone.0007909.

31.

Functional reconstruction of NANOS3 expression in the germ cell lineage by a novel transgenic reporter reveals distinct subcellular localizations of NANOS3.

Yamaji M, Tanaka T, Shigeta M, Chuma S, Saga Y, Saitou M.

Reproduction. 2010 Feb;139(2):381-93. doi: 10.1530/REP-09-0373. Epub 2009 Oct 27.

32.

Associations between PIWI proteins and TDRD1/MTR-1 are critical for integrated subcellular localization in murine male germ cells.

Kojima K, Kuramochi-Miyagawa S, Chuma S, Tanaka T, Nakatsuji N, Kimura T, Nakano T.

Genes Cells. 2009 Oct;14(10):1155-65. doi: 10.1111/j.1365-2443.2009.01342.x. Epub 2009 Sep 7.

33.

Proteomic analysis of murine Piwi proteins reveals a role for arginine methylation in specifying interaction with Tudor family members.

Vagin VV, Wohlschlegel J, Qu J, Jonsson Z, Huang X, Chuma S, Girard A, Sachidanandam R, Hannon GJ, Aravin AA.

Genes Dev. 2009 Aug 1;23(15):1749-62. doi: 10.1101/gad.1814809. Epub 2009 Jul 7.

34.

Loss of the Mili-interacting Tudor domain-containing protein-1 activates transposons and alters the Mili-associated small RNA profile.

Reuter M, Chuma S, Tanaka T, Franz T, Stark A, Pillai RS.

Nat Struct Mol Biol. 2009 Jun;16(6):639-46. doi: 10.1038/nsmb.1615. Epub 2009 May 24.

PMID:
19465913
35.

In vitro germ cell differentiation from cynomolgus monkey embryonic stem cells.

Yamauchi K, Hasegawa K, Chuma S, Nakatsuji N, Suemori H.

PLoS One. 2009;4(4):e5338. doi: 10.1371/journal.pone.0005338. Epub 2009 Apr 28.

36.

Mili interacts with tudor domain-containing protein 1 in regulating spermatogenesis.

Wang J, Saxe JP, Tanaka T, Chuma S, Lin H.

Curr Biol. 2009 Apr 28;19(8):640-4. doi: 10.1016/j.cub.2009.02.061. Epub 2009 Apr 2.

37.

Abnormal DNA methyltransferase expression in mouse germline stem cells results in spermatogenic defects.

Takashima S, Takehashi M, Lee J, Chuma S, Okano M, Hata K, Suetake I, Nakatsuji N, Miyoshi H, Tajima S, Tanaka Y, Toyokuni S, Sasaki H, Kanatsu-Shinohara M, Shinohara T.

Biol Reprod. 2009 Jul;81(1):155-64. doi: 10.1095/biolreprod.108.074708. Epub 2009 Feb 18.

PMID:
19228594
38.

Ultrastructural characterization of spermatogenesis and its evolutionary conservation in the germline: germinal granules in mammals.

Chuma S, Hosokawa M, Tanaka T, Nakatsuji N.

Mol Cell Endocrinol. 2009 Jul 10;306(1-2):17-23. doi: 10.1016/j.mce.2008.11.009. Epub 2008 Nov 21. Review.

PMID:
19063939
39.

Homing of mouse spermatogonial stem cells to germline niche depends on beta1-integrin.

Kanatsu-Shinohara M, Takehashi M, Takashima S, Lee J, Morimoto H, Chuma S, Raducanu A, Nakatsuji N, Fässler R, Shinohara T.

Cell Stem Cell. 2008 Nov 6;3(5):533-42. doi: 10.1016/j.stem.2008.08.002.

40.

Production of transgenic rats via lentiviral transduction and xenogeneic transplantation of spermatogonial stem cells.

Kanatsu-Shinohara M, Kato M, Takehashi M, Morimoto H, Takashima S, Chuma S, Nakatsuji N, Hirabayashi M, Shinohara T.

Biol Reprod. 2008 Dec;79(6):1121-8. doi: 10.1095/biolreprod.108.071159. Epub 2008 Aug 6.

PMID:
18685123
41.

Long-term culture of male germline stem cells from hamster testes.

Kanatsu-Shinohara M, Muneto T, Lee J, Takenaka M, Chuma S, Nakatsuji N, Horiuchi T, Shinohara T.

Biol Reprod. 2008 Apr;78(4):611-7. Epub 2007 Dec 19.

PMID:
18094355
42.

[Germ granule in mammals and its structural and molecular conservation].

Chuma S, Nakatsuji N.

Tanpakushitsu Kakusan Koso. 2007 Dec;52(16 Suppl):2102-8. Review. Japanese. No abstract available.

PMID:
21089279
43.

Tudor-related proteins TDRD1/MTR-1, TDRD6 and TDRD7/TRAP: domain composition, intracellular localization, and function in male germ cells in mice.

Hosokawa M, Shoji M, Kitamura K, Tanaka T, Noce T, Chuma S, Nakatsuji N.

Dev Biol. 2007 Jan 1;301(1):38-52. Epub 2006 Nov 6.

44.

Tdrd1/Mtr-1, a tudor-related gene, is essential for male germ-cell differentiation and nuage/germinal granule formation in mice.

Chuma S, Hosokawa M, Kitamura K, Kasai S, Fujioka M, Hiyoshi M, Takamune K, Noce T, Nakatsuji N.

Proc Natl Acad Sci U S A. 2006 Oct 24;103(43):15894-9. Epub 2006 Oct 12.

45.

Rats produced by interspecies spermatogonial transplantation in mice and in vitro microinsemination.

Shinohara T, Kato M, Takehashi M, Lee J, Chuma S, Nakatsuji N, Kanatsu-Shinohara M, Hirabayashi M.

Proc Natl Acad Sci U S A. 2006 Sep 12;103(37):13624-8. Epub 2006 Aug 30.

46.

Testatin transgenic and knockout mice exhibit normal sex-differentiation.

Hasegawa K, Chuma S, Tada T, Sakurai T, Tamura M, Suemori H, Nakatsuji N.

Biochem Biophys Res Commun. 2006 Mar 10;341(2):369-75. Epub 2006 Jan 19.

PMID:
16427609
47.

RNF17, a component of the mammalian germ cell nuage, is essential for spermiogenesis.

Pan J, Goodheart M, Chuma S, Nakatsuji N, Page DC, Wang PJ.

Development. 2005 Sep;132(18):4029-39. Epub 2005 Aug 10.

48.

RNA interference during spermatogenesis in mice.

Shoji M, Chuma S, Yoshida K, Morita T, Nakatsuji N.

Dev Biol. 2005 Jun 15;282(2):524-34.

49.

Genomic imprinting of XX spermatogonia and XX oocytes recovered from XX<-->XY chimeric testes.

Isotani A, Nakanishi T, Kobayashi S, Lee J, Chuma S, Nakatsuji N, Ishino F, Okabe M.

Proc Natl Acad Sci U S A. 2005 Mar 15;102(11):4039-44. Epub 2005 Mar 3.

50.

Spermatogenesis from epiblast and primordial germ cells following transplantation into postnatal mouse testis.

Chuma S, Kanatsu-Shinohara M, Inoue K, Ogonuki N, Miki H, Toyokuni S, Hosokawa M, Nakatsuji N, Ogura A, Shinohara T.

Development. 2005 Jan;132(1):117-22. Epub 2004 Dec 2.

Supplemental Content

Support Center