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Items: 49

1.

Cell-Free Expression of Sodium Channel Domains for Pharmacology Studies. Noncanonical Spider Toxin Binding Site in the Second Voltage-Sensing Domain of Human Nav1.4 Channel.

Myshkin MY, Männikkö R, Krumkacheva OA, Kulbatskii DS, Chugunov AO, Berkut AA, Paramonov AS, Shulepko MA, Fedin MV, Hanna MG, Kullmann DM, Bagryanskaya EG, Arseniev AS, Kirpichnikov MP, Lyukmanova EN, Vassilevski AA, Shenkarev ZO.

Front Pharmacol. 2019 Sep 4;10:953. doi: 10.3389/fphar.2019.00953. eCollection 2019.

2.

Protein Surface Topography as a tool to enhance the selective activity of a potassium channel blocker.

Berkut AA, Chugunov AO, Mineev KS, Peigneur S, Tabakmakher VM, Krylov NA, Oparin PB, Lihonosova AF, Novikova EV, Arseniev AS, Grishin EV, Tytgat J, Efremov RG, Vassilevski AA.

J Biol Chem. 2019 Sep 18. pii: jbc.RA119.010494. doi: 10.1074/jbc.RA119.010494. [Epub ahead of print]

3.

KV1.2 channel-specific blocker from Mesobuthus eupeus scorpion venom: Structural basis of selectivity.

Kuzmenkov AI, Nekrasova OV, Peigneur S, Tabakmakher VM, Gigolaev AM, Fradkov AF, Kudryashova KS, Chugunov AO, Efremov RG, Tytgat J, Feofanov AV, Vassilevski AA.

Neuropharmacology. 2018 Dec;143:228-238. doi: 10.1016/j.neuropharm.2018.09.030. Epub 2018 Sep 22.

PMID:
30248306
4.

C-Terminal residues in small potassium channel blockers OdK1 and OSK3 from scorpion venom fine-tune the selectivity.

Kuzmenkov AI, Peigneur S, Chugunov AO, Tabakmakher VM, Efremov RG, Tytgat J, Grishin EV, Vassilevski AA.

Biochim Biophys Acta Proteins Proteom. 2017 May;1865(5):465-472. doi: 10.1016/j.bbapap.2017.02.001. Epub 2017 Feb 4.

PMID:
28179135
5.

NMR investigation of the isolated second voltage-sensing domain of human Nav1.4 channel.

Paramonov AS, Lyukmanova EN, Myshkin MY, Shulepko MA, Kulbatskii DS, Petrosian NS, Chugunov AO, Dolgikh DA, Kirpichnikov MP, Arseniev AS, Shenkarev ZO.

Biochim Biophys Acta Biomembr. 2017 Mar;1859(3):493-506. doi: 10.1016/j.bbamem.2017.01.004. Epub 2017 Jan 6.

6.

High-Affinity α-Conotoxin PnIA Analogs Designed on the Basis of the Protein Surface Topography Method.

Kasheverov IE, Chugunov AO, Kudryavtsev DS, Ivanov IA, Zhmak MN, Shelukhina IV, Spirova EN, Tabakmakher VM, Zelepuga EA, Efremov RG, Tsetlin VI.

Sci Rep. 2016 Nov 14;6:36848. doi: 10.1038/srep36848.

7.

Temperature-sensitive gating of TRPV1 channel as probed by atomistic simulations of its trans- and juxtamembrane domains.

Chugunov AO, Volynsky PE, Krylov NA, Nolde DE, Efremov RG.

Sci Rep. 2016 Sep 9;6:33112. doi: 10.1038/srep33112.

8.

Secreted Isoform of Human Lynx1 (SLURP-2): Spatial Structure and Pharmacology of Interactions with Different Types of Acetylcholine Receptors.

Lyukmanova EN, Shulepko MA, Shenkarev ZO, Bychkov ML, Paramonov AS, Chugunov AO, Kulbatskii DS, Arvaniti M, Dolejsi E, Schaer T, Arseniev AS, Efremov RG, Thomsen MS, Dolezal V, Bertrand D, Dolgikh DA, Kirpichnikov MP.

Sci Rep. 2016 Aug 3;6:30698. doi: 10.1038/srep30698.

9.

Central loop of non-conventional toxin WTX from Naja kaouthia is important for interaction with nicotinic acetylcholine receptors.

Lyukmanova EN, Shulepko MA, Shenkarev ZO, Kasheverov IE, Chugunov AO, Kulbatskii DS, Myshkin MY, Utkin YN, Efremov RG, Tsetlin VI, Arseniev AS, Kirpichnikov MP, Dolgikh DA.

Toxicon. 2016 Sep 1;119:274-9. doi: 10.1016/j.toxicon.2016.06.012. Epub 2016 Jun 23.

PMID:
27343701
10.

Kalium: a database of potassium channel toxins from scorpion venom.

Kuzmenkov AI, Krylov NA, Chugunov AO, Grishin EV, Vassilevski AA.

Database (Oxford). 2016 Apr 17;2016. pii: baw056. doi: 10.1093/database/baw056. Print 2016.

11.

Structural Insight into Specificity of Interactions between Nonconventional Three-finger Weak Toxin from Naja kaouthia (WTX) and Muscarinic Acetylcholine Receptors.

Lyukmanova EN, Shenkarev ZO, Shulepko MA, Paramonov AS, Chugunov AO, Janickova H, Dolejsi E, Dolezal V, Utkin YN, Tsetlin VI, Arseniev AS, Efremov RG, Dolgikh DA, Kirpichnikov MP.

J Biol Chem. 2015 Sep 25;290(39):23616-30. doi: 10.1074/jbc.M115.656595. Epub 2015 Aug 4.

12.

Rational design of new ligands for nicotinic receptors on the basis of α-conotoxin PnIA.

Kasheverov IE, Kudryavtsev DS, Ivanov IA, Zhmak MN, Chugunov AO, Tabakmakher VM, Zelepuga EA, Efremov RG, Tsetlin VI.

Dokl Biochem Biophys. 2015;461:106-9. doi: 10.1134/S1607672915020118. Epub 2015 May 5. No abstract available.

PMID:
25937226
13.

Human SLURP-1 and SLURP-2 Proteins Acting on Nicotinic Acetylcholine Receptors Reduce Proliferation of Human Colorectal Adenocarcinoma HT-29 Cells.

Lyukmanova EN, Shulepko MA, Bychkov ML, Shenkarev ZO, Paramonov AS, Chugunov AO, Arseniev AS, Dolgikh DA, Kirpichnikov MP.

Acta Naturae. 2014 Oct;6(4):60-6.

14.

Liquid but durable: molecular dynamics simulations explain the unique properties of archaeal-like membranes.

Chugunov AO, Volynsky PE, Krylov NA, Boldyrev IA, Efremov RG.

Sci Rep. 2014 Dec 12;4:7462. doi: 10.1038/srep07462.

15.

Deciphering fine molecular details of proteins' structure and function with a Protein Surface Topography (PST) method.

Koromyslova AD, Chugunov AO, Efremov RG.

J Chem Inf Model. 2014 Apr 28;54(4):1189-99. doi: 10.1021/ci500158y. Epub 2014 Apr 14.

PMID:
24689707
16.

PREDDIMER: a web server for prediction of transmembrane helical dimers.

Polyansky AA, Chugunov AO, Volynsky PE, Krylov NA, Nolde DE, Efremov RG.

Bioinformatics. 2014 Mar 15;30(6):889-90. doi: 10.1093/bioinformatics/btt645. Epub 2013 Nov 7.

PMID:
24202542
17.

Modular organization of α-toxins from scorpion venom mirrors domain structure of their targets, sodium channels.

Chugunov AO, Koromyslova AD, Berkut AA, Peigneur S, Tytgat J, Polyansky AA, Pentkovsky VM, Vassilevski AA, Grishin EV, Efremov RG.

J Biol Chem. 2013 Jun 28;288(26):19014-27. doi: 10.1074/jbc.M112.431650. Epub 2013 May 1.

18.

[Endoscopic hemostasis in patients with portal hypertension tumor genesis].

Khubutia MSh, Pinchuk TP, Sogreshilin SS, Bugaev SA, Lutsyk KN, Chugunov AO.

Eksp Klin Gastroenterol. 2012;(6):53-7. Russian.

PMID:
23402192
19.

Recent advances in computational modeling of α-helical membrane-active peptides.

Polyansky AA, Chugunov AO, Vassilevski AA, Grishin EV, Efremov RG.

Curr Protein Pept Sci. 2012 Nov;13(7):644-57. Review.

PMID:
23363529
20.

A single missense mutation in a coiled-coil domain of Escherichia coli ribosomal protein S2 confers a thermosensitive phenotype that can be suppressed by ribosomal protein S1.

Aseev LV, Chugunov AO, Efremov RG, Boni IV.

J Bacteriol. 2013 Jan;195(1):95-104. doi: 10.1128/JB.01305-12. Epub 2012 Oct 26.

21.

The role of chain rigidity in lipid self-association: comparative study of dihexanoyl- and disorbyl-phosphatidylcholines.

Semenova AA, Chugunov AO, Dubovskii PV, Chupin VV, Volynsky PE, Boldyrev IA.

Chem Phys Lipids. 2012 May;165(4):382-6. doi: 10.1016/j.chemphyslip.2011.12.004. Epub 2011 Dec 14.

PMID:
22197998
22.

[Effect of risk factors in colorectal cancer hepatic metastases].

Kovalenko IuA, Chugunov AO, Chzhao AV.

Klin Khir. 2011 Sep;(9):20-5. Russian.

PMID:
22168019
23.

[The early rehabilitation of the patients following extensive liver resection and transplantation].

Goĭdenko VS, Chzhao AV, Seraia ÉS, Lapshin VP, Zhuravel' SV, Chugunov AO, Andreĭtseva OI.

Vopr Kurortol Fizioter Lech Fiz Kult. 2011 May-Jun;(3):22-4. Russian.

PMID:
21837836
24.

Insulin receptor-related receptor as an extracellular alkali sensor.

Deyev IE, Sohet F, Vassilenko KP, Serova OV, Popova NV, Zozulya SA, Burova EB, Houillier P, Rzhevsky DI, Berchatova AA, Murashev AN, Chugunov AO, Efremov RG, Nikol'sky NN, Bertelli E, Eladari D, Petrenko AG.

Cell Metab. 2011 Jun 8;13(6):679-89. doi: 10.1016/j.cmet.2011.03.022.

25.

Evidence that interaction between conserved residues in transmembrane helices 2, 3, and 7 are crucial for human VPAC1 receptor activation.

Chugunov AO, Simms J, Poyner DR, Dehouck Y, Rooman M, Gilis D, Langer I.

Mol Pharmacol. 2010 Sep;78(3):394-401. doi: 10.1124/mol.110.063578. Epub 2010 Jun 23.

PMID:
20573782
26.

[Volume of surgical resection by liver focal lesions].

Chzhao AV, Kovalenko IuA, Chugunov AO, Novruzbekov MS.

Khirurgiia (Mosk). 2010;(5):15-20. Russian.

PMID:
20559205
27.

[Prediction of the spatial structure of proteins: emphasis on membrane targets].

Chugunov AO, Efremov RG.

Bioorg Khim. 2009 Nov-Dec;35(6):744-60. Review. Russian.

PMID:
20208575
28.

[Laserotherapy and mesodiencephalic modulation after hemihepatoectomy in the early postoperative period].

Goĭdenko VS, Seraia EV, Chzao AV, Lapshin VP, Zhuravel' SV, Chugunov AO, Andreĭtseva OI, Riumin AO.

Vopr Kurortol Fizioter Lech Fiz Kult. 2009 Jan-Feb;(1):39-40. Russian. No abstract available.

PMID:
19288600
29.

PLATINUM: a web tool for analysis of hydrophobic/hydrophilic organization of biomolecular complexes.

Pyrkov TV, Chugunov AO, Krylov NA, Nolde DE, Efremov RG.

Bioinformatics. 2009 May 1;25(9):1201-2. doi: 10.1093/bioinformatics/btp111. Epub 2009 Feb 25.

PMID:
19244385
30.

[Early hospital rehabilitation of patients after liver transplantation].

Seraia EV, Chzhao AV, Lapshin VP, Chugunov AO, Zhuravel' SV, Andriĭtseva OI.

Vopr Kurortol Fizioter Lech Fiz Kult. 2008 May-Jun;(3):25-7. Russian. No abstract available.

PMID:
18652181
31.

[Therapeutic exercises, physiotherapy and massage in combined rehabilitation of patients after liver resection in the early hospital stage].

Seraia EV, Chzhao AV, Lapshin VP, Chugunov AO, Zhuravel' SV.

Vopr Kurortol Fizioter Lech Fiz Kult. 2008 Jan-Feb;(1):47-8. Russian. No abstract available.

PMID:
18368827
32.

Homology modeling of MT1 and MT2 receptors.

Farce A, Chugunov AO, Logé C, Sabaouni A, Yous S, Dilly S, Renault N, Vergoten G, Efremov RG, Lesieur D, Chavatte P.

Eur J Med Chem. 2008 Sep;43(9):1926-44. doi: 10.1016/j.ejmech.2007.12.001. Epub 2007 Dec 14.

PMID:
18255198
33.

A novel method for packing quality assessment of transmembrane alpha-helical domains in proteins.

Chugunov AO, Novoseletsky VN, Arseniev AS, Efremov RG.

Biochemistry (Mosc). 2007 Mar;72(3):293-300.

PMID:
17447882
34.

Method to assess packing quality of transmembrane alpha-helices in proteins. 2. Validation by "correct vs misleading" test.

Chugunov AO, Novoseletsky VN, Nolde DE, Arseniev AS, Efremov RG.

J Chem Inf Model. 2007 May-Jun;47(3):1163-70. Epub 2007 Mar 20.

PMID:
17371006
35.

Method to assess packing quality of transmembrane alpha-helices in proteins. 1. Parametrization using structural data.

Chugunov AO, Novoseletsky VN, Nolde DE, Arseniev AS, Efremov RG.

J Chem Inf Model. 2007 May-Jun;47(3):1150-62. Epub 2007 Mar 20.

PMID:
17371005
36.

Molecular lipophilicity in protein modeling and drug design.

Efremov RG, Chugunov AO, Pyrkov TV, Priestle JP, Arseniev AS, Jacoby E.

Curr Med Chem. 2007;14(4):393-415. Review.

PMID:
17305542
37.
38.

[Actual problems of donation in liver transplantation. Part 1].

Ermolov AS, Chzhao AV, Guliaev VA, Pogrebnichenko IV, Zhuravel' SV, Dzhagraev KR, Andreĭtseva OI, Kuznetsova NK, Lutsyk KN, Novruzbekov MS, Chugunov AO.

Khirurgiia (Mosk). 2002;(2):51-8. Review. Russian. No abstract available.

PMID:
12418328
39.

[Actual problems of donation in liver transplantation. Part 2].

Ermolov AS, Chzhao AV, Guliaev VA, Pogrebnichenko IV, Zhuravel' SV, Dzhagraev KR, Andreĭtseva OI, Kuznetsova NK, Lutsyk KN, Novruzbekov MS, Chugunov AO.

Khirurgiia (Mosk). 2002;(3):48-51. Review. Russian. No abstract available.

PMID:
11975036
40.

[Mode of surgery completion in peritonitis].

Shurkalin BK, Kriger AG, Gorskiĭ VA, Chugunov AO, Rzhebaev KE, Cherevatenko AM, Glushkov PS, Shogenov AA.

Khirurgiia (Mosk). 2000;(2):33-7. Russian.

PMID:
10710917
41.

[The efficacy of different antimicrobial preparations in treating patients with disseminated peritonitis].

Shurkalin BK, Busch W, Kriger AG, Levanov AV, Chugunov AO, Korshunov VM.

Zh Mikrobiol Epidemiol Immunobiol. 1994 Jul-Aug;(4):28-32. Russian.

PMID:
7992529
42.

[The effect of different antimicrobial preparations on the normalization of the intestinal microflora in patients with disseminated peritonitis].

Levanov AV, Busch W, Shurkalin BK, Kriger AG, Chugunov AO, Korshunov VM.

Zh Mikrobiol Epidemiol Immunobiol. 1993 Mar-Apr;(2):32-8. Russian.

PMID:
8059569
43.

[Ciprofloxacin and other antimicrobial drugs in the treatment of disseminated peritonitis].

Levanov AV, Bush V, Shurkalin BK, Kriger AG, Gorskiĭ VA, Chugunov AO, Korshumov VM.

Antibiot Khimioter. 1992 Dec;37(12):46-9. Russian.

PMID:
1304132
44.

[Treatment of peritonitis of appendicular etiology].

Shurkalin BK, Kriger AG, Gorskiĭ VA, Bunin AA, Chugunov AO.

Khirurgiia (Mosk). 1990 Feb;(2):97-100. Russian.

PMID:
2335901
45.

[Characteristics of the course of peritonitis in relation to the degree of perforation of the gastrointestinal tract].

Shurkalin BK, Korshunov VM, Kriger AG, Gorskiĭ VA, Chugunov AO.

Vestn Khir Im I I Grek. 1989 Aug;144(8):21-4. Russian.

PMID:
2603300
46.

[Semi-open and open methods of treating disseminated purulent peritonitis].

Shurkalin BK, Kriger AG, Chugunov AO.

Khirurgiia (Mosk). 1989 Feb;(2):7-10. Russian. No abstract available.

PMID:
2709722
47.

[Complications of non-clostridial anaerobic peritonitis].

Shurkalin BK, Kriger AG, Chugunov AO, Pavlova MV.

Vestn Khir Im I I Grek. 1988 Mar;140(3):50-4. Russian.

PMID:
2970148
48.

[Surgical tactics in anaerobic non-clostridial peritonitis].

Shurkalin BK, Kriger AG, Korshunov VM, Vladimirov VG, Chugunov AO.

Vestn Khir Im I I Grek. 1988 Jan;140(1):74-7. Russian.

PMID:
3289239
49.

[5-fluorouracil in the treatment and prevention of acute pancreatitis].

Kubyshkin VA, Chzhao AV, Chugunov AO.

Vestn Khir Im I I Grek. 1982 Aug;129(8):132-4. Review. Russian. No abstract available.

PMID:
6182676

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