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Items: 1 to 50 of 132

1.

Corrigendum to "SARC018_SPORE02: Phase II Study of Mocetinostat Administered with Gemcitabine for Patients with Metastatic Leiomyosarcoma with Progression or Relapse following Prior Treatment with Gemcitabine-Containing Therapy".

Choy E, Ballman K, Chen J, Dickson MA, Chugh R, George S, Okuno S, Pollock R, Patel RM, Hoering A, Patel S.

Sarcoma. 2019 Aug 27;2019:7608743. doi: 10.1155/2019/7608743. eCollection 2019.

2.

The Fontan Thromboprophylaxis Dilemma: To Give, or What Not to Give.

Chugh R.

J Am Coll Cardiol. 2019 Aug 27;74(8):1082-1085. doi: 10.1016/j.jacc.2019.07.021. No abstract available.

PMID:
31439218
3.

Targeting Sporadic and Neurofibromatosis Type 1 (NF1) Related Refractory Malignant Peripheral Nerve Sheath Tumors (MPNST) in a Phase II Study of Everolimus in Combination with Bevacizumab (SARC016).

Widemann BC, Lu Y, Reinke D, Okuno SH, Meyer CF, Cote GM, Chugh R, Milhem MM, Hirbe AC, Kim A, Turpin B, Pressey JG, Dombi E, Jayaprakash N, Helman LJ, Onwudiwe N, Cichowski K, Perentesis JP.

Sarcoma. 2019 Jul 24;2019:7656747. doi: 10.1155/2019/7656747. eCollection 2019.

4.

Use of the facial artery-based cutaneous island flap (melo-labial flap) for reconstruction of the neopharynx following total laryngectomy: a novel technique.

Gupta DK, Chugh R, Singh SK, Pati S.

BMJ Case Rep. 2019 Aug 4;12(8). pii: e230712. doi: 10.1136/bcr-2019-230712.

PMID:
31383687
5.

Nonalcoholic Fatty Liver Disease: The Overlooked Complication of Type 2 Diabetes.

Akshintala D, Chugh R, Amer F, Cusi K.

In: Feingold KR, Anawalt B, Boyce A, Chrousos G, Dungan K, Grossman A, Hershman JM, Kaltsas G, Koch C, Kopp P, Korbonits M, McLachlan R, Morley JE, New M, Perreault L, Purnell J, Rebar R, Singer F, Trence DL, Vinik A, Wilson DP, editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-.
2019 Jul 9.

6.

Correction: Triptolide-induced cell death in pancreatic cancer is mediated by O-GlcNAc modification of transcription factor Sp1.

Banerjee S, Sangwan V, McGinn O, Chugh R, Dudeja V, Vickers SM, Saluja AK.

J Biol Chem. 2019 Jul 5;294(27):10739. doi: 10.1074/jbc.AAC119.009844. No abstract available.

7.

A phase 1 and randomized controlled phase 2 trial of the safety and efficacy of the combination of gemcitabine and docetaxel with ontuxizumab (MORAb-004) in metastatic soft-tissue sarcomas.

Jones RL, Chawla SP, Attia S, Schöffski P, Gelderblom H, Chmielowski B, Le Cesne A, Van Tine BA, Trent JC, Patel S, Wagner AJ, Chugh R, Heyburn JW, Weil SC, Wang W, Viele K, Maki RG.

Cancer. 2019 Jul 15;125(14):2445-2454. doi: 10.1002/cncr.32084. Epub 2019 Apr 29.

8.

Primary Cardiac Sarcoma: A Rare, Aggressive Malignancy with a High Propensity for Brain Metastases.

Siontis BL, Zhao L, Leja M, McHugh JB, Shango MM, Baker LH, Schuetze SM, Chugh R.

Sarcoma. 2019 Mar 10;2019:1960593. doi: 10.1155/2019/1960593. eCollection 2019.

9.

Successful embryo cryopreservation immediately following a full-term delivery in a woman with newly diagnosed Ewing's sarcoma.

Giuliani E, Ellman EM, Chugh R, Moravek MB.

J Assist Reprod Genet. 2019 May;36(5):1023-1028. doi: 10.1007/s10815-019-01445-6. Epub 2019 Apr 5. No abstract available.

PMID:
30953232
10.

Doxorubicin plus the IGF-1R antibody cixutumumab in soft tissue sarcoma: a phase I study using the TITE-CRM model.

Chugh R, Griffith KA, Davis EJ, Thomas DG, Zavala JD, Metko G, Brockstein B, Undevia SD, Stadler WM, Schuetze SM.

Ann Oncol. 2019 Feb 5. doi: 10.1093/annonc/mdy557. [Epub ahead of print] No abstract available.

PMID:
30726873
11.

Prevalence of Hepatitis B Virus, Hepatitis C Virus, and HIV Infection Among Patients With Newly Diagnosed Cancer From Academic and Community Oncology Practices.

Ramsey SD, Unger JM, Baker LH, Little RF, Loomba R, Hwang JP, Chugh R, Konerman MA, Arnold K, Menter AR, Thomas E, Michels RM, Jorgensen CW, Burton GV, Bhadkamkar NA, Hershman DL.

JAMA Oncol. 2019 Apr 1;5(4):497-505. doi: 10.1001/jamaoncol.2018.6437. Erratum in: JAMA Oncol. 2019 Mar 7;:.

PMID:
30653226
12.

A phase 1 dose escalation and expansion study of Tarextumab (OMP-59R5) in patients with solid tumors.

Smith DC, Chugh R, Patnaik A, Papadopoulos KP, Wang M, Kapoun AM, Xu L, Dupont J, Stagg RJ, Tolcher A.

Invest New Drugs. 2019 Aug;37(4):722-730. doi: 10.1007/s10637-018-0714-6. Epub 2018 Dec 28.

13.

Canonical Wnt/β-catenin signaling activation in soft-tissue sarcomas: A comparative study of synovial sarcoma and leiomyosarcoma.

Briski LM, Thomas DG, Patel RM, Lawlor ER, Chugh R, McHugh JB, Lucas DR.

Rare Tumors. 2018 Nov 25;10:2036361318813431. doi: 10.1177/2036361318813431. eCollection 2018.

14.

SARC018_SPORE02: Phase II Study of Mocetinostat Administered with Gemcitabine for Patients with Metastatic Leiomyosarcoma with Progression or Relapse following Prior Treatment with Gemcitabine-Containing Therapy.

Choy E, Ballman K, Chen J, Dickson MA, Chugh R, George S, Okuno S, Pollock R, Patel RM, Hoering A, Patel S.

Sarcoma. 2018 Oct 24;2018:2068517. doi: 10.1155/2018/2068517. eCollection 2018. Erratum in: Sarcoma. 2019 Aug 27;2019:7608743.

15.

Electrocardiographic Effects of a Supratherapeutic Dose of WCK 2349, a Benzoquinolizine Fluoroquinolone.

Mason JW, Chugh R, Patel A, Gutte R, Bhatia A.

Clin Transl Sci. 2019 Jan;12(1):47-52. doi: 10.1111/cts.12594. Epub 2018 Nov 27.

16.

A first-in-human phase 1a study of the bispecific anti-DLL4/anti-VEGF antibody navicixizumab (OMP-305B83) in patients with previously treated solid tumors.

Jimeno A, Moore KN, Gordon M, Chugh R, Diamond JR, Aljumaily R, Mendelson D, Kapoun AM, Xu L, Stagg R, Smith DC.

Invest New Drugs. 2019 Jun;37(3):461-472. doi: 10.1007/s10637-018-0665-y. Epub 2018 Sep 19.

PMID:
30229512
17.

Notch pathway inhibition with LY3039478 in soft tissue sarcoma and gastrointestinal stromal tumours.

Mir O, Azaro A, Merchan J, Chugh R, Trent J, Rodon J, Ohnmacht U, Diener JT, Smith C, Yuen E, Oakley GJ 3rd, Le Cesne A, Soria JC, Benhadji KA, Massard C.

Eur J Cancer. 2018 Nov;103:88-97. doi: 10.1016/j.ejca.2018.08.012. Epub 2018 Sep 12.

PMID:
30218977
18.

Plasma and Intrapulmonary Concentrations of Cefepime and Zidebactam following Intravenous Administration of WCK 5222 to Healthy Adult Subjects.

Rodvold KA, Gotfried MH, Chugh R, Gupta M, Patel A, Chavan R, Yeole R, Friedland HD, Bhatia A.

Antimicrob Agents Chemother. 2018 Jul 27;62(8). pii: e00682-18. doi: 10.1128/AAC.00682-18. Print 2018 Aug.

19.

Association of Dasatinib With Progression-Free Survival Among Patients With Advanced Gastrointestinal Stromal Tumors Resistant to Imatinib.

Schuetze SM, Bolejack V, Thomas DG, von Mehren M, Patel S, Samuels B, Choy E, D'Amato G, Staddon AP, Ganjoo KN, Chow WA, Rushing DA, Forscher CA, Priebat DA, Loeb DM, Chugh R, Okuno S, Reinke DK, Baker LH.

JAMA Oncol. 2018 Jun 1;4(6):814-820. doi: 10.1001/jamaoncol.2018.0601.

20.

Adolescent and Young Adult Oncology, Version 2.2018, NCCN Clinical Practice Guidelines in Oncology.

Coccia PF, Pappo AS, Beaupin L, Borges VF, Borinstein SC, Chugh R, Dinner S, Folbrecht J, Frazier AL, Goldsby R, Gubin A, Hayashi R, Huang MS, Link MP, Livingston JA, Matloub Y, Millard F, Oeffinger KC, Puccetti D, Reed D, Robinson S, Rosenberg AR, Sanft T, Spraker-Perlman HL, von Mehren M, Wechsler DS, Whelan KF, Yeager N, Gurski LA, Shead DA.

J Natl Compr Canc Netw. 2018 Jan;16(1):66-97. doi: 10.6004/jnccn.2018.0001.

PMID:
29295883
21.

Spotlight on olaratumab in the treatment of soft-tissue sarcoma: design, development, and place in therapy.

Davis EJ, Chugh R.

Drug Des Devel Ther. 2017 Dec 13;11:3579-3587. doi: 10.2147/DDDT.S121298. eCollection 2017. Review.

22.

Intrapulmonary Pharmacokinetics of Levonadifloxacin following Oral Administration of Alalevonadifloxacin to Healthy Adult Subjects.

Rodvold KA, Gotfried MH, Chugh R, Gupta M, Yeole R, Patel A, Bhatia A.

Antimicrob Agents Chemother. 2018 Feb 23;62(3). pii: e02297-17. doi: 10.1128/AAC.02297-17. Print 2018 Mar.

23.

Rapid, ultra low coverage copy number profiling of cell-free DNA as a precision oncology screening strategy.

Hovelson DH, Liu CJ, Wang Y, Kang Q, Henderson J, Gursky A, Brockman S, Ramnath N, Krauss JC, Talpaz M, Kandarpa M, Chugh R, Tuck M, Herman K, Grasso CS, Quist MJ, Feng FY, Haakenson C, Langmore J, Kamberov E, Tesmer T, Husain H, Lonigro RJ, Robinson D, Smith DC, Alva AS, Hussain MH, Chinnaiyan AM, Tewari M, Mills RE, Morgan TM, Tomlins SA.

Oncotarget. 2017 Sep 22;8(52):89848-89866. doi: 10.18632/oncotarget.21163. eCollection 2017 Oct 27.

24.

A First-in-Human Phase I Study of the Anticancer Stem Cell Agent Ipafricept (OMP-54F28), a Decoy Receptor for Wnt Ligands, in Patients with Advanced Solid Tumors.

Jimeno A, Gordon M, Chugh R, Messersmith W, Mendelson D, Dupont J, Stagg R, Kapoun AM, Xu L, Uttamsingh S, Brachmann RK, Smith DC.

Clin Cancer Res. 2017 Dec 15;23(24):7490-7497. doi: 10.1158/1078-0432.CCR-17-2157. Epub 2017 Sep 27.

25.

Integrative clinical genomics of metastatic cancer.

Robinson DR, Wu YM, Lonigro RJ, Vats P, Cobain E, Everett J, Cao X, Rabban E, Kumar-Sinha C, Raymond V, Schuetze S, Alva A, Siddiqui J, Chugh R, Worden F, Zalupski MM, Innis J, Mody RJ, Tomlins SA, Lucas D, Baker LH, Ramnath N, Schott AF, Hayes DF, Vijai J, Offit K, Stoffel EM, Roberts JS, Smith DC, Kunju LP, Talpaz M, Cieślik M, Chinnaiyan AM.

Nature. 2017 Aug 17;548(7667):297-303. doi: 10.1038/nature23306. Epub 2017 Aug 2.

26.

Comparison of Plasma and Intrapulmonary Concentrations of Nafithromycin (WCK 4873) in Healthy Adult Subjects.

Rodvold KA, Gotfried MH, Chugh R, Gupta M, Friedland HD, Bhatia A.

Antimicrob Agents Chemother. 2017 Aug 24;61(9). pii: e01096-17. doi: 10.1128/AAC.01096-17. Print 2017 Sep.

27.

A Collaborative Approach to Childhood Obesity Surveillance From a Local Health Department.

Alleman E, Murphy E, Baskerville K, Chugh R.

J Public Health Manag Pract. 2017 Nov/Dec;23(6):e17-e20. doi: 10.1097/PHH.0000000000000615.

PMID:
28628581
28.

Next generation sequencing of extraskeletal myxoid chondrosarcoma.

Davis EJ, Wu YM, Robinson D, Schuetze SM, Baker LH, Athanikar J, Cao X, Kunju LP, Chinnaiyan AM, Chugh R.

Oncotarget. 2017 Mar 28;8(13):21770-21777. doi: 10.18632/oncotarget.15568.

29.

Phase I, Dose-Escalation, Two-Part Trial of the PARP Inhibitor Talazoparib in Patients with Advanced Germline BRCA1/2 Mutations and Selected Sporadic Cancers.

de Bono J, Ramanathan RK, Mina L, Chugh R, Glaspy J, Rafii S, Kaye S, Sachdev J, Heymach J, Smith DC, Henshaw JW, Herriott A, Patterson M, Curtin NJ, Byers LA, Wainberg ZA.

Cancer Discov. 2017 Jun;7(6):620-629. doi: 10.1158/2159-8290.CD-16-1250. Epub 2017 Feb 27.

30.

Minnelide Inhibits Androgen Dependent, Castration Resistant Prostate Cancer Growth by Decreasing Expression of Androgen Receptor Full Length and Splice Variants.

Isharwal S, Modi S, Arora N, Uhlrich C 3rd, Giri B, Barlass U, Soubra A, Chugh R, Dehm SM, Dudeja V, Saluja A, Banerjee S, Konety B.

Prostate. 2017 May;77(6):584-596. doi: 10.1002/pros.23298. Epub 2017 Feb 1.

31.

An optimization protocol for Swiss 3T3 feeder cell growth-arrest by Mitomycin C dose-to-volume derivation strategy.

Chugh RM, Chaturvedi M, Yerneni LK.

Cytotechnology. 2017 Apr;69(2):391-404. doi: 10.1007/s10616-017-0064-9. Epub 2017 Jan 21.

32.

A Phase I Study of the Cyclin-Dependent Kinase 4/6 Inhibitor Ribociclib (LEE011) in Patients with Advanced Solid Tumors and Lymphomas.

Infante JR, Cassier PA, Gerecitano JF, Witteveen PO, Chugh R, Ribrag V, Chakraborty A, Matano A, Dobson JR, Crystal AS, Parasuraman S, Shapiro GI.

Clin Cancer Res. 2016 Dec 1;22(23):5696-5705. Epub 2016 Aug 19.

33.

Phase 2 study of dasatinib in patients with alveolar soft part sarcoma, chondrosarcoma, chordoma, epithelioid sarcoma, or solitary fibrous tumor.

Schuetze SM, Bolejack V, Choy E, Ganjoo KN, Staddon AP, Chow WA, Tawbi HA, Samuels BL, Patel SR, von Mehren M, D'Amato G, Leu KM, Loeb DM, Forscher CA, Milhem MM, Rushing DA, Lucas DR, Chugh R, Reinke DK, Baker LH.

Cancer. 2017 Jan 1;123(1):90-97. doi: 10.1002/cncr.30379. Epub 2016 Oct 3.

34.

Renal Papillary Necrosis Caused by Protein C Deficiency Leading to Recurrent Hydronephrosis.

Chugh RK, Olorunnisomo V, Fowle EJ, Modica I, Meisels I, Gupta M.

J Endourol Case Rep. 2016 Feb 1;2(1):36-7. doi: 10.1089/cren.2016.0018. eCollection 2016.

35.

Assessment of Imaging Modalities and Response Metrics in Ewing Sarcoma: Correlation With Survival.

Koshkin VS, Bolejack V, Schwartz LH, Wahl RL, Chugh R, Reinke DK, Zhao B, O JH, Patel SR, Schuetze SM, Baker LH.

J Clin Oncol. 2016 Oct 20;34(30):3680-3685. doi: 10.1200/JCO.2016.68.1858.

36.

SPARC expression in patients with high-risk localized soft tissue sarcoma treated on a randomized phase II trial of neo/adjuvant chemotherapy.

Davis EJ, Zhao L, Lucas DR, Schuetze SM, Baker LH, Zalupski MM, Thomas D, Chugh R.

BMC Cancer. 2016 Aug 20;16:663. doi: 10.1186/s12885-016-2694-2.

37.

A bivalent promoter contributes to stress-induced plasticity of CXCR4 in Ewing sarcoma.

Krook MA, Hawkins AG, Patel RM, Lucas DR, Van Noord R, Chugh R, Lawlor ER.

Oncotarget. 2016 Sep 20;7(38):61775-61788. doi: 10.18632/oncotarget.11240.

38.

Activation of Wnt/β-Catenin in Ewing Sarcoma Cells Antagonizes EWS/ETS Function and Promotes Phenotypic Transition to More Metastatic Cell States.

Pedersen EA, Menon R, Bailey KM, Thomas DG, Van Noord RA, Tran J, Wang H, Qu PP, Hoering A, Fearon ER, Chugh R, Lawlor ER.

Cancer Res. 2016 Sep 1;76(17):5040-53. doi: 10.1158/0008-5472.CAN-15-3422. Epub 2016 Jun 30.

39.

Exposure cell number during feeder cell growth-arrest by Mitomycin C is a critical pharmacological aspect in stem cell culture system.

Chugh RM, Chaturvedi M, Yerneni LK.

J Pharmacol Toxicol Methods. 2016 Jul-Aug;80:68-74. doi: 10.1016/j.vascn.2016.05.006. Epub 2016 May 10.

PMID:
27178105
40.

Stepwise development of a cancer care delivery research study to evaluate the prevalence of virus infections in cancer patients.

Unger JM, Hershman DL, Arnold KB, Loomba R, Chugh R, Hwang JP, O'Rourke MA, Bhadkamkar NA, Wang LX, Siegel AB, Cooley TP, Berenberg JL, Bridges BB, Ramsey SD.

Future Oncol. 2016 May;12(10):1219-31. doi: 10.2217/fon-2015-0076. Epub 2016 Mar 8.

41.

Associations of vitamin D status, bone health and anthropometry, with gross motor development and performance of school-aged Indian children who were born at term with low birth weight.

Filteau S, Rehman AM, Yousafzai A, Chugh R, Kaur M, Sachdev HP, Trilok-Kumar G.

BMJ Open. 2016 Jan 8;6(1):e009268. doi: 10.1136/bmjopen-2015-009268.

42.

SARC009: Phase 2 study of dasatinib in patients with previously treated, high-grade, advanced sarcoma.

Schuetze SM, Wathen JK, Lucas DR, Choy E, Samuels BL, Staddon AP, Ganjoo KN, von Mehren M, Chow WA, Loeb DM, Tawbi HA, Rushing DA, Patel SR, Thomas DG, Chugh R, Reinke DK, Baker LH.

Cancer. 2016 Mar 15;122(6):868-74. doi: 10.1002/cncr.29858. Epub 2015 Dec 28.

43.

A Novel Immunocompetent Mouse Model of Pancreatic Cancer with Robust Stroma: a Valuable Tool for Preclinical Evaluation of New Therapies.

Majumder K, Arora N, Modi S, Chugh R, Nomura A, Giri B, Dawra R, Ramakrishnan S, Banerjee S, Saluja A, Dudeja V.

J Gastrointest Surg. 2016 Jan;20(1):53-65; discussion 65. doi: 10.1007/s11605-015-2985-y. Epub 2015 Nov 18.

44.

Poor Vitamin D Status in Healthy Populations in India: A Review of Current Evidence.

Trilok Kumar G, Chugh R, Eggersdorfer M.

Int J Vitam Nutr Res. 2015;85(3-4):185-201. doi: 10.1024/0300-9831/a000228. Epub 2015 Nov 17. Review.

45.

Meningococcal disease among men who have sex with men - United States, January 2012-June 2015.

Kamiya H, MacNeil J, Blain A, Patel M, Martin S, Weiss D, Ngai S, Ezeoke I, Mascola L, Civen R, Ngo V, Black S, Kemble S, Chugh R, Murphy E, Petit C, Harriman K, Winter K, Beron A, Clegg W, Conover C, Misegades L.

MMWR Morb Mortal Wkly Rep. 2015 Nov 13;64(44):1256-7. doi: 10.15585/mmwr.mm6444a6.

46.

An evaluation of the choice of feeder cell growth arrest for the production of cultured epidermis.

Chugh RM, Chaturvedi M, Yerneni LK.

Burns. 2015 Dec;41(8):1788-1795. doi: 10.1016/j.burns.2015.08.011. Epub 2015 Sep 29.

PMID:
26392024
47.

Aldoxorubicin in Sarcoma: Teaching an Old Drug New Tricks.

Chugh R, Schuetze SM.

JAMA Oncol. 2015 Dec;1(9):1280-1. doi: 10.1001/jamaoncol.2015.3221. No abstract available.

PMID:
26379207
48.

The use of exome capture RNA-seq for highly degraded RNA with application to clinical cancer sequencing.

Cieslik M, Chugh R, Wu YM, Wu M, Brennan C, Lonigro R, Su F, Wang R, Siddiqui J, Mehra R, Cao X, Lucas D, Chinnaiyan AM, Robinson D.

Genome Res. 2015 Sep;25(9):1372-81. doi: 10.1101/gr.189621.115. Epub 2015 Aug 7.

49.

Effects of vitamin D supplementation in infancy on growth, bone parameters, body composition and gross motor development at age 3-6 years: follow-up of a randomized controlled trial.

Trilok-Kumar G, Kaur M, Rehman AM, Arora H, Rajput MM, Chugh R, Kurpad A, Sachdev HS, Filteau S.

Int J Epidemiol. 2015 Jun;44(3):894-905. doi: 10.1093/ije/dyv116. Epub 2015 Jun 30.

PMID:
26130740
50.

Lack of Transmission among Close Contacts of Patient with Case of Middle East Respiratory Syndrome Imported into the United States, 2014.

Breakwell L, Pringle K, Chea N, Allen D, Allen S, Richards S, Pantones P, Sandoval M, Liu L, Vernon M, Conover C, Chugh R, DeMaria A, Burns R, Smole S, Gerber SI, Cohen NJ, Kuhar D, Haynes LM, Schneider E, Kumar A, Kapoor M, Madrigal M, Swerdlow DL, Feikin DR.

Emerg Infect Dis. 2015 Jul;21(7):1128-34. doi: 10.3201/eid2107.150054.

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