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Molecular heterogeneity unravelled by single-cell transcriptomics in patients with essential thrombocythaemia.

Hsu CC, Chen YJ, Huang CE, Wu YY, Wang MC, Pei SN, Liao CK, Lu CH, Chen PT, Tsou HY, Li CP, Chuang WH, Chuang CK, Yang CY, Lai YH, Lin YH, Chen CC.

Br J Haematol. 2019 Oct 14. doi: 10.1111/bjh.16225. [Epub ahead of print]


Pharmacokinetics and pharmacodynamics of pegylated interferon for the treatment of hepatitis B.

Yeh ML, Huang JF, Dai CY, Yu ML, Chuang WL.

Expert Opin Drug Metab Toxicol. 2019 Oct 12:1-7. doi: 10.1080/17425255.2019.1678584. [Epub ahead of print]


APASL HCV guidelines of virus-eradicated patients by DAA on how to monitor HCC occurrence and HBV reactivation.

Kanda T, Lau GKK, Wei L, Moriyama M, Yu ML, Chuang WL, Ibrahim A, Lesmana CRA, Sollano J, Kumar M, Jindal A, Sharma BC, Hamid SS, Kadir Dokmeci A, Mamun-Al-Mahtab, McCaughan GW, Wasim J, Crawford DHG, Kao JH, Ooka Y, Yokosuka O, Sarin SK, Omata M.

Hepatol Int. 2019 Sep 20. doi: 10.1007/s12072-019-09988-7. [Epub ahead of print]


Continuous Finger Gesture Recognition Based on Flex Sensors.

Chuang WC, Hwang WJ, Tai TM, Huang DR, Jhang YJ.

Sensors (Basel). 2019 Sep 15;19(18). pii: E3986. doi: 10.3390/s19183986.


Genomic and phenotypic evaluation of rice susceptible check TN1 collected in Taiwan.

Li Y, Huang YF, Huang SH, Kuang YH, Tung CW, Liao CT, Chuang WP.

Bot Stud. 2019 Aug 29;60(1):19. doi: 10.1186/s40529-019-0269-7.


Direct-acting antivirals in East Asian hepatitis C patients: real-world experience from the REAL-C Consortium.

Huang CF, Iio E, Jun DW, Ogawa E, Toyoda H, Hsu YC, Haga H, Iwane S, Enomoto M, Lee DH, Wong G, Liu CH, Tada T, Chuang WL, Cheung R, Hayashi J, Tseng CH, Yasuda S, Tran S, Kam L, Henry L, Jeong JY, Nomura H, Park SH, Nakamuta M, Huang JF, Tai CM, Lo GH, Lee MH, Yang HI, Kao JH, Tamori A, Eguchi Y, Ueno Y, Furusyo N, Tanaka Y, Yu ML, Nguyen MH; REAL-C Investigators.

Hepatol Int. 2019 Sep;13(5):587-598. doi: 10.1007/s12072-019-09974-z. Epub 2019 Aug 28.


Improvement of hyperuricemia in chronic hepatitis C patients receiving directly acting antiviral agents.

Jang TY, Huang CI, Yeh ML, Liang PC, Tsai PC, Lin YH, Hsieh MY, Hou NJ, Lin ZY, Chen SC, Huang JF, Dai CY, Huang CF, Chuang WL, Yu ML.

J Gastroenterol Hepatol. 2019 Aug 14. doi: 10.1111/jgh.14835. [Epub ahead of print]


Wisteria floribunda agglutinin-positive Mac-2-binding protein in the prediction of disease severity in chronic hepatitis B patients.

Yeh ML, Huang CF, Huang CI, Dai CY, Lin IH, Liang PC, Hsieh MH, Lin ZY, Chen SC, Huang JF, Chen JJ, Yu ML, Chuang WL.

PLoS One. 2019 Aug 8;14(8):e0220663. doi: 10.1371/journal.pone.0220663. eCollection 2019.


Ribavirin facilitates early viral kinetics in chronic hepatitis C patients receiving daclatasvir/asunaprevir.

Huang CF, Yeh ML, Huang CI, Liang PC, Lin YH, Hsieh MY, Chen KY, Ko YM, Lin ZY, Chen SC, Huang JF, Dai CY, Chuang WL, Yu ML.

J Gastroenterol Hepatol. 2019 Aug 1. doi: 10.1111/jgh.14815. [Epub ahead of print]


Single-Junction Organic Solar Cell Containing a Fluorinated Heptacyclic Carbazole-Based Ladder-Type Acceptor Affords over 13% Efficiency with Solution-Processed Cross-Linkable Fullerene as an Interfacial Layer.

Chen TW, Chang CC, Hsiao YT, Chan C, Hong L, Zhong L, Chuang WT, Hou J, Li Y, Hsu CS.

ACS Appl Mater Interfaces. 2019 Aug 28;11(34):31069-31077. doi: 10.1021/acsami.9b09044. Epub 2019 Aug 14.


Exploring the Brain Responses to Driving Fatigue Through Simultaneous EEG and fNIRS Measurements.

Lin CT, King JT, Chuang CH, Ding W, Chuang WY, Liao LD, Wang YK.

Int J Neural Syst. 2019 Jun 4:1950018. doi: 10.1142/S0129065719500187. [Epub ahead of print]


Reproductive Regulation and Oxidative Stress Alleviation of Chinese Herbal Medicine Therapy in Ovariectomised Mouse Model.

Wu CH, Wang SE, Hsu CH, Hsu YT, Lu CW, Chuang WC, Lee MC.

Evid Based Complement Alternat Med. 2019 Jul 7;2019:5346518. doi: 10.1155/2019/5346518. eCollection 2019.


Higher NAFLD fibrosis score is associated with impaired eGFR.

Hsieh MH, Wu KT, Chen YY, Yang JF, Lin WY, Chang NC, Lin CY, Huang CK, Wang CL, Chuang HY, Lin SC, Hsu YK, Tsai YS, Chuang WL, Yu ML, Dai CY.

J Formos Med Assoc. 2019 Jul 25. pii: S0929-6646(19)30160-3. doi: 10.1016/j.jfma.2019.07.007. [Epub ahead of print]


Potential Negative Effects of Dextromethorphan as an Add-On Therapy to Methylphenidate in Children With ADHD.

Chuang WC, Yeh CB, Wang SC, Pan PY, Shyu JF, Liu YP, Gau SS, Lu RB.

Front Psychiatry. 2019 Jun 26;10:437. doi: 10.3389/fpsyt.2019.00437. eCollection 2019.


Large-scale viral genome analysis identifies novel clinical associations between hepatitis B virus and chronically infected patients.

Podlaha O, Gane E, Brunetto M, Fung S, Chuang WL, Pan CQ, Jiang Z, Liu Y, Bhardwaj N, Mukherjee P, Flaherty J, Gaggar A, Subramanian M, Izumi N, Shalimar, Lim YS, Marcellin P, Buti M, Chan HLY, Agarwal K.

Sci Rep. 2019 Jul 19;9(1):10529. doi: 10.1038/s41598-019-46609-7.


Blockade of STAT3 Signaling Contributes to Anticancer Effect of 5-Acetyloxy-6,7,8,4'-Tetra-Methoxyflavone, a Tangeretin Derivative, on Human Glioblastoma Multiforme Cells.

Cheng YP, Li S, Chuang WL, Li CH, Chen GJ, Chang CC, Or CR, Lin PY, Chang CC.

Int J Mol Sci. 2019 Jul 9;20(13). pii: E3366. doi: 10.3390/ijms20133366.


The prognostic factors between different viral etiologies among advanced hepatocellular carcinoma patients receiving sorafenib treatment.

Yeh ML, Huang CF, Huang CI, Hsieh MY, Hou NJ, Lin IH, Liang PC, Tsai YS, Hsieh MH, Lin ZY, Chen SC, Dai CY, Huang JF, Yu ML, Chuang WL.

Kaohsiung J Med Sci. 2019 Oct;35(10):624-632. doi: 10.1002/kjm2.12105. Epub 2019 Jun 28.


Benzyl Isothiocyanate and Phenethyl Isothiocyanate Inhibit Adipogenesis and Hepatosteatosis in Mice with Obesity Induced by a High-Fat Diet.

Chuang WT, Liu YT, Huang CS, Lo CW, Yao HT, Chen HW, Lii CK.

J Agric Food Chem. 2019 Jun 26;67(25):7136-7146. doi: 10.1021/acs.jafc.9b02668. Epub 2019 Jun 18.


Induction of nuclear protein-1 by thyroid hormone enhances platelet-derived growth factor A mediated angiogenesis in liver cancer.

Chen CY, Wu SM, Lin YH, Chi HC, Lin SL, Yeh CT, Chuang WY, Lin KH.

Theranostics. 2019 Apr 13;9(8):2361-2379. doi: 10.7150/thno.29628. eCollection 2019.


FaPEx® Multipesticide Residues Extraction Kit for Minimizing Sample Preparation Time in Agricultural Produce.

Chuang WC, Chen JW, Huang CH, Shyu TH, Lin SK.

J AOAC Int. 2019 May 16. doi: 10.5740/jaoacint.18-0271. [Epub ahead of print]


Axl and autophagy LC3 expression in tumors is strongly associated with clinical prognosis of hepatocellular carcinoma patients after curative resection.

Hsu CC, Hsieh PM, Chen YS, Lo GH, Lin HY, Dai CY, Huang JF, Chuang WL, Chen YL, Yu ML, Lin CW.

Cancer Med. 2019 Jul;8(7):3453-3463. doi: 10.1002/cam4.2229. Epub 2019 May 16.


Integrated care for methadone maintenance patients with hepatitis C virus infection.

Tai CM, Yen YC, Bair MJ, Tseng CH, Chang TT, Huang CF, Yeh ML, Dai CY, Chuang WL, Yu ML, Huang JF.

Kaohsiung J Med Sci. 2019 Aug;35(8):501-507. doi: 10.1002/kjm2.12086. Epub 2019 May 14.


Prognostic significance of pretreatment neutrophil-to-lymphocyte ratio in older patients with metastatic cancer.

Chen KH, Tsang NM, Chou WC, Tai SF, Liu SC, Lei KF, Chang KP, Chuang WC, Pai PC.

J Geriatr Oncol. 2019 Sep;10(5):757-762. doi: 10.1016/j.jgo.2019.04.015. Epub 2019 May 10.


Equal treatment efficacy of direct-acting antivirals in patients with chronic hepatitis C and hepatocellular carcinoma? A prospective cohort study.

Huang CF, Yeh ML, Huang CI, Liang PC, Lin YH, Hsieh MY, Wei YJ, Lin ZY, Chen SC, Huang JF, Dai CY, Chuang WL, Yu ML.

BMJ Open. 2019 May 5;9(5):e026703. doi: 10.1136/bmjopen-2018-026703.


Transition from video-assisted thoracoscopic to robotic esophagectomy: a single surgeon's experience.

Chao YK, Wen YW, Chuang WY, Cerfolio RJ.

Dis Esophagus. 2019 Apr 25. pii: doz033. doi: 10.1093/dote/doz033. [Epub ahead of print]


Mac-2 Binding Protein Glycosylation Isomer as a Hepatocellular Carcinoma Marker in Patients With Chronic Hepatitis B or C Infection.

Jun T, Hsu YC, Ogawa S, Huang YT, Yeh ML, Tseng CH, Huang CF, Tai CM, Dai CY, Huang JF, Chuang WL, Yu ML, Tanaka Y, Nguyen MH.

Hepatol Commun. 2019 Feb 8;3(4):493-503. doi: 10.1002/hep4.1321. eCollection 2019 Apr.


Clinical evaluation of IntelliPlexTM HCV genotyping kit for hepatitis C virus genotyping.

Kao JH, Lin CY, Chuang WL, Cheng YY, Hu JY, Liang WK, Friebe P, Palmer S, Huang CS.

Diagn Microbiol Infect Dis. 2019 Aug;94(4):344-348. doi: 10.1016/j.diagmicrobio.2019.02.020. Epub 2019 Mar 12.


An open-label, randomized, active control trial of 8 versus 12 weeks of elbasvir/grazoprevir for treatment-naïve chronic hepatitis C genotype 1b patients with mild fibrosis (EGALITE): Impact of baseline viral loads and NS5A resistance-associated substitution.

Huang CF, Hung CH, Cheng PN, Bair MJ, Huang YH, Kao JH, Hsu SJ, Lee PL, Chen JJ, Chien RN, Peng CY, Lin CY, Hsieh TY, Cheng CH, Dai CY, Huang JF, Chuang WL, Yu ML.

J Infect Dis. 2019 Apr 8. pii: jiz154. doi: 10.1093/infdis/jiz154. [Epub ahead of print]


Risk stratification of non-alcoholic fatty liver disease across body mass index in a community basis.

Huang JF, Tsai PC, Yeh ML, Huang CF, Huang CI, Hsieh MH, Dai CY, Yang JF, Chen SC, Yu ML, Chuang WL, Chang WY.

J Formos Med Assoc. 2019 Apr 2. pii: S0929-6646(19)30005-1. doi: 10.1016/j.jfma.2019.03.014. [Epub ahead of print]


Elevated interleukin-4 levels predicted advanced fibrosis in chronic hepatitis C.

Batsaikhan B, Lu MY, Yeh ML, Huang CI, Huang CF, Lin ZY, Chen SC, Huang JF, Hsieh PH, Chuang WL, Lee JC, Yu ML, Dai CY.

J Chin Med Assoc. 2019 Apr;82(4):277-281. doi: 10.1097/JCMA.0000000000000064.


A Facial Nerve Schwannoma Presenting as an External Auditory Canal Mass.

Hu CY, Wu YM, Chuang WY, Chan KC.

Ear Nose Throat J. 2019 Mar;98(3):123-125. doi: 10.1177/0145561318824893. Epub 2019 Jan 30. No abstract available.


The prognosis of bulky hepatocellular carcinoma with nonmajor branch portal vein tumor thrombosis.

Jang TY, Huang CI, Yeh ML, Lin ZY, Chen SC, Chuang WL.

Medicine (Baltimore). 2019 Mar;98(13):e15066. doi: 10.1097/MD.0000000000015066.


Galactosylsphingosine does not interfere with the quantitation of plasma glucosylsphingosine levels in Gaucher patients.

Chuang WL, Pacheco J, Hoxha D, Sanderink G, Sung C.

Clin Chim Acta. 2019 Jul;494:48-51. doi: 10.1016/j.cca.2019.03.009. Epub 2019 Mar 8.


Elevated serum ferritin level associated with hepatic steatosis and fibrosis in hepatitis C virus-infected patients.

Batsaikhan B, Gantumur G, Huang CI, Yeh ML, Huang CF, Lin ZY, Chen SC, Huang JF, Yu ML, Chuang WL, Lee JC, Dai CY.

J Chin Med Assoc. 2019 Feb;82(2):99-104. doi: 10.1097/JCMA.0000000000000009.


Correction: Prorenin receptor acts as a potential molecular target for pancreatic ductal adenocarcinoma diagnosis.

Arundhathi A, Chuang WH, Chen JK, Wang SE, Shyr YM, Chen JY, Liao WN, Chen HW, Teng YM, Pai CC, Wang CH.

Oncotarget. 2019 Jan 11;10(4):558. doi: 10.18632/oncotarget.26597. eCollection 2019 Jan 11.


Successful Resolution of Left Ventricular Thrombus after ST-Elevation Myocardial Infarction by Edoxaban in a Patient with High Bleeding Risk.

Cheong KI, Chuang WP, Wu YW, Huang SH.

Acta Cardiol Sin. 2019 Jan;35(1):85-88. doi: 10.6515/ACS.201901_35(1).20180912A. No abstract available.


CCM111 prevents hepatic fibrosis via cooperative inhibition of TGF-β, Wnt and STAT3 signaling pathways.

Lin IY, Chiou YS, Wu LC, Tsai CY, Chen CT, Chuang WC, Lee MC, Lin CC, Lin TT, Chen SC, Pan MH, Ma N.

J Food Drug Anal. 2019 Jan;27(1):184-194. doi: 10.1016/j.jfda.2018.09.008. Epub 2018 Oct 25.


Renal chymase-dependent pathway for angiotensin II formation mediated acute kidney injury in a mouse model of aristolochic acid I-induced acute nephropathy.

Hsieh WY, Chang TH, Chang HF, Chuang WH, Lu LC, Yang CW, Lin CS, Chang CC.

PLoS One. 2019 Jan 11;14(1):e0210656. doi: 10.1371/journal.pone.0210656. eCollection 2019.


Sequential Photodynamic Therapy with Phthalocyanine Encapsulated Chitosan-Tripolyphosphate Nanoparticles and Flucytosine Treatment against Candida tropicalis.

Hsieh YH, Chuang WC, Yu KH, Jheng CP, Lee CI.

Pharmaceutics. 2019 Jan 4;11(1). pii: E16. doi: 10.3390/pharmaceutics11010016.


A simple approach for the ultrasensitive detection of paraquat residue in adzuki beans by surface-enhanced Raman scattering.

Tsen CM, Yu CW, Chuang WC, Chen MJ, Lin SK, Shyu TH, Wang YH, Li CC, Chao WC, Chuang CY.

Analyst. 2019 Jan 21;144(2):426-438. doi: 10.1039/c8an01845f. Epub 2018 Dec 20.


APASL clinical practice recommendation: how to treat HCV-infected patients with renal impairment?

Kanda T, Lau GKK, Wei L, Moriyama M, Yu ML, Chuang WL, Ibrahim A, Lesmana CRA, Sollano J, Kumar M, Jindal A, Sharma BC, Hamid SS, Dokmeci AK, Mamun-Al-Mahtab, McCaughan GW, Wasim J, Crawford DHG, Kao JH, Yokosuka O, Sarin SK, Omata M.

Hepatol Int. 2019 Mar;13(2):103-109. doi: 10.1007/s12072-018-9915-5. Epub 2018 Dec 11.


Efficacy and safety of 12 weeks of daclatasvir, asunaprevir plus ribavirin for HCV genotype-1b infection without NS5A resistance-associated substitutions.

Yu ML, Hung CH, Huang YH, Peng CY, Lin CY, Cheng PN, Chien RN, Hsu SJ, Liu CH, Huang CF, Su CW, Huang JF, Liu CJ, Kao JH, Chuang WL, Chen PJ, Chen DS.

J Formos Med Assoc. 2019 Feb;118(2):556-564. doi: 10.1016/j.jfma.2018.11.007. Epub 2018 Dec 5.


Taiwan consensus statement on the management of chronic hepatitis B.

Chien RN, Kao JH, Peng CY, Chen CH, Liu CJ, Huang YH, Hu TH, Yang HI, Lu SN, Ni YH, Chuang WL, Lee CM, Wu JC, Chen PJ, Liaw YF.

J Formos Med Assoc. 2019 Jan;118(1 Pt 1):7-38. doi: 10.1016/j.jfma.2018.11.008. Epub 2018 Dec 6.


Iatrogenic external auditory canal cholesteatoma with mastoid erosion.

Lee YH, Hu CY, Chuang WY, Chan KC.

Ear Nose Throat J. 2018 Oct-Nov;97(10-11):340-344. No abstract available.


Indoor ozone levels, houseplants and peak expiratory flow rates among healthy adults in Taipei, Taiwan.

Chang LT, Hong GB, Weng SP, Chuang HC, Chang TY, Liu CW, Chuang WY, Chuang KJ.

Environ Int. 2019 Jan;122:231-236. doi: 10.1016/j.envint.2018.11.010. Epub 2018 Nov 19.


Pretreatment Hepatitis B Viral Load Predicts Long-Term Hepatitis B Response After Anti-Hepatitis C Therapy in Hepatitis B/C Dual-Infected Patients.

Yeh ML, Huang CI, Huang CF, Hsieh MH, Liu TW, Lin YH, Liang PC, Hsieh MY, Lin ZY, Chen SC, Huang JF, Kuo PL, Dai CY, Yu ML, Chuang WL.

J Infect Dis. 2019 Apr 8;219(8):1224-1233. doi: 10.1093/infdis/jiy648.


Post-treatment fibrotic modifications overwhelm pretreatment liver fibrosis in predicting HCC in CHC patients with curative antivirals.

Huang CF, Yeh ML, Huang CI, Liang PC, Lin YH, Lin ZY, Chen SC, Huang JF, Dai CY, Chuang WL, Yu ML.

Hepatol Int. 2018 Nov;12(6):544-551. doi: 10.1007/s12072-018-9908-4. Epub 2018 Nov 13.


Thyroid hormone negatively regulates tumorigenesis through suppression of BC200.

Lin YH, Wu MH, Huang YH, Yeh CT, Chi HC, Tsai CY, Chuang WY, Yu CJ, Chung IH, Chen CY, Lin KH.

Endocr Relat Cancer. 2018 Dec 1;25(12):967-979. doi: 10.1530/ERC-18-0176.


Updates in the management and treatment of HCV genotype 3, what are the remaining challenges?

Huang JF, Huang CF, Yeh ML, Dai CY, Yu ML, Chuang WL.

Expert Rev Anti Infect Ther. 2018 Dec;16(12):907-912. doi: 10.1080/14787210.2018.1544492. Epub 2018 Nov 9. Review.


Association of hyperuricemia with disease severity in chronic hepatitis C patients.

Jang TY, Yeh ML, Huang CI, Lin ZY, Chen SC, Hsieh MH, Dai CY, Huang JF, Huang CF, Chuang WL, Yu ML.

PLoS One. 2018 Nov 5;13(11):e0207043. doi: 10.1371/journal.pone.0207043. eCollection 2018.

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