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Items: 31

1.

Prioritizing Crohn's disease genes by integrating association signals with gene expression implicates monocyte subsets.

Gettler K, Giri M, Kenigsberg E, Martin J, Chuang LS, Hsu NY, Denson LA, Hyams JS, Griffiths A, Noe JD, Crandall WV, Mack DR, Kellermayer R, Abraham C, Hoffman G, Kugathasan S, Cho JH.

Genes Immun. 2019 Jan 29. doi: 10.1038/s41435-019-0059-y. [Epub ahead of print]

PMID:
30692607
2.

RUNX Poly(ADP-Ribosyl)ation and BLM Interaction Facilitate the Fanconi Anemia Pathway of DNA Repair.

Tay LS, Krishnan V, Sankar H, Chong YL, Chuang LSH, Tan TZ, Kolinjivadi AM, Kappei D, Ito Y.

Cell Rep. 2018 Aug 14;24(7):1747-1755. doi: 10.1016/j.celrep.2018.07.038.

3.

Functional variants in the LRRK2 gene confer shared effects on risk for Crohn's disease and Parkinson's disease.

Hui KY, Fernandez-Hernandez H, Hu J, Schaffner A, Pankratz N, Hsu NY, Chuang LS, Carmi S, Villaverde N, Li X, Rivas M, Levine AP, Bao X, Labrias PR, Haritunians T, Ruane D, Gettler K, Chen E, Li D, Schiff ER, Pontikos N, Barzilai N, Brant SR, Bressman S, Cheifetz AS, Clark LN, Daly MJ, Desnick RJ, Duerr RH, Katz S, Lencz T, Myers RH, Ostrer H, Ozelius L, Payami H, Peter Y, Rioux JD, Segal AW, Scott WK, Silverberg MS, Vance JM, Ubarretxena-Belandia I, Foroud T, Atzmon G, Pe'er I, Ioannou Y, McGovern DPB, Yue Z, Schadt EE, Cho JH, Peter I.

Sci Transl Med. 2018 Jan 10;10(423). pii: eaai7795. doi: 10.1126/scitranslmed.aai7795.

4.

TGFβ Promotes Genomic Instability after Loss of RUNX3.

Krishnan V, Chong YL, Tan TZ, Kulkarni M, Bin Rahmat MB, Tay LS, Sankar H, Jokhun DS, Ganesan A, Chuang LSH, Voon DC, Shivashankar GV, Thiery JP, Ito Y.

Cancer Res. 2018 Jan 1;78(1):88-102. doi: 10.1158/0008-5472.CAN-17-1178. Epub 2017 Oct 26.

5.

Roles of RUNX in Solid Tumors.

Chuang LS, Ito K, Ito Y.

Adv Exp Med Biol. 2017;962:299-320. doi: 10.1007/978-981-10-3233-2_19. Review.

PMID:
28299665
6.

Molecular mechanism and therapeutic implications of selinexor (KPT-330) in liposarcoma.

Garg M, Kanojia D, Mayakonda A, Said JW, Doan NB, Chien W, Ganesan TS, Chuang LS, Venkatachalam N, Baloglu E, Shacham S, Kauffman M, Koeffler HP.

Oncotarget. 2017 Jan 31;8(5):7521-7532. doi: 10.18632/oncotarget.13485.

7.

Aurora kinase and RUNX: Reaching beyond transcription.

Chuang LS, Krishnan V, Ito Y.

Cell Cycle. 2016 Nov 16;15(22):2999-3000. Epub 2016 Aug 5. No abstract available.

8.

A Frameshift in CSF2RB Predominant Among Ashkenazi Jews Increases Risk for Crohn's Disease and Reduces Monocyte Signaling via GM-CSF.

Chuang LS, Villaverde N, Hui KY, Mortha A, Rahman A, Levine AP, Haritunians T, Evelyn Ng SM, Zhang W, Hsu NY, Facey JA, Luong T, Fernandez-Hernandez H, Li D, Rivas M, Schiff ER, Gusev A, Schumm LP, Bowen BM, Sharma Y, Ning K, Remark R, Gnjatic S, Legnani P, George J, Sands BE, Stempak JM, Datta LW, Lipka S, Katz S, Cheifetz AS, Barzilai N, Pontikos N, Abraham C, Dubinsky MJ, Targan S, Taylor K, Rotter JI, Scherl EJ, Desnick RJ, Abreu MT, Zhao H, Atzmon G, Pe'er I, Kugathasan S, Hakonarson H, McCauley JL, Lencz T, Darvasi A, Plagnol V, Silverberg MS, Muise AM, Brant SR, Daly MJ, Segal AW, Duerr RH, Merad M, McGovern DP, Peter I, Cho JH.

Gastroenterology. 2016 Oct;151(4):710-723.e2. doi: 10.1053/j.gastro.2016.06.045. Epub 2016 Jul 1.

9.

Aurora kinase-induced phosphorylation excludes transcription factor RUNX from the chromatin to facilitate proper mitotic progression.

Chuang LS, Khor JM, Lai SK, Garg S, Krishnan V, Koh CG, Lee SH, Ito Y.

Proc Natl Acad Sci U S A. 2016 Jun 7;113(23):6490-5. doi: 10.1073/pnas.1523157113. Epub 2016 May 23.

10.

RUNX3 is a novel negative regulator of oncogenic TEAD-YAP complex in gastric cancer.

Qiao Y, Lin SJ, Chen Y, Voon DC, Zhu F, Chuang LS, Wang T, Tan P, Lee SC, Yeoh KG, Sudol M, Ito Y.

Oncogene. 2016 May 19;35(20):2664-74. doi: 10.1038/onc.2015.338. Epub 2015 Sep 14.

PMID:
26364597
11.

Disease-associated variants in different categories of disease located in distinct regulatory elements.

Ma M, Ru Y, Chuang LS, Hsu NY, Shi LS, Hakenberg J, Cheng WY, Uzilov A, Ding W, Glicksberg BS, Chen R.

BMC Genomics. 2015;16 Suppl 8:S3. doi: 10.1186/1471-2164-16-S8-S3. Epub 2015 Jun 18.

12.

The RUNX family: developmental regulators in cancer.

Ito Y, Bae SC, Chuang LS.

Nat Rev Cancer. 2015 Feb;15(2):81-95. doi: 10.1038/nrc3877. Epub 2015 Jan 16. Review.

PMID:
25592647
13.

Runx3 inactivation is a crucial early event in the development of lung adenocarcinoma.

Lee YS, Lee JW, Jang JW, Chi XZ, Kim JH, Li YH, Kim MK, Kim DM, Choi BS, Kim EG, Chung JH, Lee OJ, Lee YM, Suh JW, Chuang LS, Ito Y, Bae SC.

Cancer Cell. 2013 Nov 11;24(5):603-16. doi: 10.1016/j.ccr.2013.10.003.

14.

RUNX family: Regulation and diversification of roles through interacting proteins.

Chuang LS, Ito K, Ito Y.

Int J Cancer. 2013 Mar 15;132(6):1260-71. doi: 10.1002/ijc.27964. Epub 2012 Dec 19. Review.

15.

RUNX3 interactome reveals novel centrosomal targeting of RUNX family of transcription factors.

Chuang LS, Lai SK, Murata-Hori M, Yamada A, Li HY, Gunaratne J, Ito Y.

Cell Cycle. 2012 May 15;11(10):1938-47. doi: 10.4161/cc.20278. Epub 2012 May 15.

PMID:
22544322
16.

RUNX3 functions as an oncogene in ovarian cancer.

Lee CW, Chuang LS, Kimura S, Lai SK, Ong CW, Yan B, Salto-Tellez M, Choolani M, Ito Y.

Gynecol Oncol. 2011 Aug;122(2):410-7. doi: 10.1016/j.ygyno.2011.04.044. Epub 2011 May 25.

PMID:
21612813
17.

Newborn GnRH neurons in the adult forebrain of the ring dove.

Cheng MF, Alexander K, Zhou S, Bonder E, Chuang LS.

Horm Behav. 2011 Jun;60(1):94-104. doi: 10.1016/j.yhbeh.2011.03.008. Epub 2011 Apr 3.

PMID:
21443878
18.

Loss of Runx3 is a key event in inducing precancerous state of the stomach.

Ito K, Chuang LS, Ito T, Chang TL, Fukamachi H, Salto-Tellez M, Ito Y.

Gastroenterology. 2011 May;140(5):1536-46.e8. doi: 10.1053/j.gastro.2011.01.043. Epub 2011 Jan 27.

PMID:
21277301
19.

RUNX3 is multifunctional in carcinogenesis of multiple solid tumors.

Chuang LS, Ito Y.

Oncogene. 2010 May 6;29(18):2605-15. doi: 10.1038/onc.2010.88. Epub 2010 Mar 29. Review.

PMID:
20348954
20.

RUNX3 attenuates beta-catenin/T cell factors in intestinal tumorigenesis.

Ito K, Lim AC, Salto-Tellez M, Motoda L, Osato M, Chuang LS, Lee CW, Voon DC, Koo JK, Wang H, Fukamachi H, Ito Y.

Cancer Cell. 2008 Sep 9;14(3):226-37. doi: 10.1016/j.ccr.2008.08.004. Erratum in: Cancer Cell. 2009 Mar 3;15(3):240.

21.

Predictive models of molecular machines involved in Caenorhabditis elegans early embryogenesis.

Gunsalus KC, Ge H, Schetter AJ, Goldberg DS, Han JD, Hao T, Berriz GF, Bertin N, Huang J, Chuang LS, Li N, Mani R, Hyman AA, Sönnichsen B, Echeverri CJ, Roth FP, Vidal M, Piano F.

Nature. 2005 Aug 11;436(7052):861-5.

22.

New genes with roles in the C. elegans embryo revealed using RNAi of ovary-enriched ORFeome clones.

Fernandez AG, Gunsalus KC, Huang J, Chuang LS, Ying N, Liang HL, Tang C, Schetter AJ, Zegar C, Rual JF, Hill DE, Reinke V, Vidal M, Piano F.

Genome Res. 2005 Feb;15(2):250-9.

23.

The human papillomavirus-18 genome is efficiently targeted by cellular DNA methylation.

Badal S, Badal V, Calleja-Macias IE, Kalantari M, Chuang LS, Li BF, Bernard HU.

Virology. 2004 Jul 1;324(2):483-92.

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27.

Human DNA-(cytosine-5) methyltransferase-PCNA complex as a target for p21WAF1.

Chuang LS, Ian HI, Koh TW, Ng HH, Xu G, Li BF.

Science. 1997 Sep 26;277(5334):1996-2000.

29.
30.

The 14-MeV neutron activation analysis of Chinese medicines for protein, phosphorus, potassium and magnesium contents.

Chuang LS, Yue KW, Chan PK, Chiu WY.

Comp Med East West. 1978 Spring;6(1):37-56.

PMID:
710077
31.

Methods of localized irradiation of material by low energy or short range charged particles.

Chuang LS.

Health Phys. 1970 Sep;19(3):439-42. No abstract available.

PMID:
5512927

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