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Items: 6


Monoclonal Antibody Targeting Sialyl-di-Lewisa-Containing Internalizing and Noninternalizing Glycoproteins with Cancer Immunotherapy Development Potential.

Tivadar ST, McIntosh RS, Chua JX, Moss R, Parsons T, Zaitoun AM, Madhusudan S, Durrant LG, Vankemmelbeke M.

Mol Cancer Ther. 2020 Mar;19(3):790-801. doi: 10.1158/1535-7163.MCT-19-0221. Epub 2019 Dec 23.


The terminal sialic acid of stage-specific embryonic antigen-4 has a crucial role in binding to a cancer-targeting antibody.

Soliman C, Chua JX, Vankemmelbeke M, McIntosh RS, Guy AJ, Spendlove I, Durrant LG, Ramsland PA.

J Biol Chem. 2020 Jan 24;295(4):1009-1020. doi: 10.1074/jbc.RA119.011518. Epub 2019 Dec 12.


Combination Treatment with an Antibody-Drug Conjugate (A1mcMMAF) Targeting the Oncofetal Glycoprotein 5T4 and Carboplatin Improves Survival in a Xenograft Model of Ovarian Cancer.

Wan YL, Sapra P, Bolton J, Chua JX, Durrant LG, Stern PL.

Target Oncol. 2019 Aug;14(4):465-477. doi: 10.1007/s11523-019-00650-8. Erratum in: Target Oncol. 2019 Oct 3;:.


Cancer cell associated glycans as targets for immunotherapy.

Vankemmelbeke M, Chua JX, Durrant LG.

Oncoimmunology. 2015 Jul 15;5(1):e1061177. eCollection 2016.


Monoclonal Antibodies Targeting LecLex-Related Glycans with Potent Antitumor Activity.

Chua JX, Vankemmelbeke M, McIntosh RS, Clarke PA, Moss R, Parsons T, Spendlove I, Zaitoun AM, Madhusudan S, Durrant LG.

Clin Cancer Res. 2015 Jul 1;21(13):2963-74. doi: 10.1158/1078-0432.CCR-14-3030. Epub 2015 Mar 16.

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