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Mortality Among Children with Down syndrome in Hong Kong: A Population-Based Cohort Study from Birth.

Chua GT, Tung KTS, Wong ICK, Lum TYS, Wong WHS, Chow CB, Ho FK, Wong RS, Ip P.

J Pediatr. 2020 Jan 9. pii: S0022-3476(19)31514-8. doi: 10.1016/j.jpeds.2019.11.006. [Epub ahead of print]


Glyceryl trinitrate to reduce the need for manual removal of retained placenta following vaginal delivery: the GOT-IT RCT.

Denison FC, Carruthers KF, Hudson J, McPherson G, Scotland G, Brook-Smith S, Clarkson C, Peace M, Brewin J, Chua GN, Hallowell N, Norman JE, Lawton J, Norrie J.

Health Technol Assess. 2019 Dec;23(70):1-72. doi: 10.3310/hta23700.


Nitroglycerin for treatment of retained placenta: A randomised, placebo-controlled, multicentre, double-blind trial in the UK.

Denison FC, Carruthers KF, Hudson J, McPherson G, Chua GN, Peace M, Brewin J, Hallowell N, Scotland G, Lawton J, Norrie J, Norman JE; GOT-IT investigator team.

PLoS Med. 2019 Dec 30;16(12):e1003001. doi: 10.1371/journal.pmed.1003001. eCollection 2019 Dec.


Sexual behaviors and intention for cervical screening among HPV-vaccinated young Chinese females.

Chua GT, Ho FK, Tung KT, Wong RS, Cheong KN, Yip PS, Fan SY, Wong WH, Qiao Y, Chui CS, Li SX, Ip P.

Vaccine. 2019 Nov 27. pii: S0264-410X(19)31573-7. doi: 10.1016/j.vaccine.2019.11.044. [Epub ahead of print]


Are heart doses associated with survival in patients with non-small cell lung cancer who received post-operative thoracic radiotherapy?: A national population-based study.

Lee CC, Chua GWY, Zheng H, Soon YY, Foo LL, Thiagarajan A, Yap SP, Siow TR, Ng WL, Chua KLM, Yip C, Chia BSH, Ng YY, Master Z, Tan PW, Tan YI, Leong YF, Loria JFE, Vellayappan B, Koh WY, Leong CN, Tey JCS, Tham IWK, Fong KW.

Medicine (Baltimore). 2019 Aug;98(35):e17020. doi: 10.1097/MD.0000000000017020.


Skin prick testing a better predictor than blood testing for the diagnosis of peanut allergy in Chinese children.

Chua GT, Chong PC, Au EY, Cheong KN, Wong WH, Chan EY, Ho MH, Lau YL, Duque JSR.

Asian Pac J Allergy Immunol. 2019 Jul 16. doi: 10.12932/AP-110319-0519. [Epub ahead of print]


Medication Safety: A Need to Relook at Double-Checking Medicines?

Chua GP, Lee KH, Peralta GD, Lim JHC.

Asia Pac J Oncol Nurs. 2019 Jul-Sep;6(3):246-252. doi: 10.4103/apjon.apjon_2_19.


Cytosine-Based TET Enzyme Inhibitors.

Chua GNL, Wassarman KL, Sun H, Alp JA, Jarczyk EI, Kuzio NJ, Bennett MJ, Malachowsky BG, Kruse M, Kennedy AJ.

ACS Med Chem Lett. 2019 Jan 31;10(2):180-185. doi: 10.1021/acsmedchemlett.8b00474. eCollection 2019 Feb 14.


iTRAQ-based analysis of leaf proteome identifies important proteins in secondary metabolite biosynthesis and defence pathways crucial to cross-protection against TMV.

Das PP, Chua GM, Lin Q, Wong SM.

J Proteomics. 2019 Mar 30;196:42-56. doi: 10.1016/j.jprot.2019.02.002. Epub 2019 Feb 3.


Romidepsin enhances the efficacy of cytarabine in vivo, revealing histone deacetylase inhibition as a promising therapeutic strategy for KMT2A-rearranged infant acute lymphoblastic leukemia.

Cheung LC, Cruickshank MN, Hughes AM, Singh S, Chua GA, Ford J, Ferrari E, Oommen J, Malinge S, Lock RB, Kees UR, Kotecha RS.

Haematologica. 2019 Jul;104(7):e300-e303. doi: 10.3324/haematol.2018.192906. Epub 2019 Jan 24. No abstract available.


Using a Chemical Genetic Screen to Enhance Our Understanding of the Antimicrobial Properties of Gallium against Escherichia coli.

Gugala N, Chatfield-Reed K, Turner RJ, Chua G.

Genes (Basel). 2019 Jan 9;10(1). pii: E34. doi: 10.3390/genes10010034.


Differential Hepatic Gene Expression Profile of Male Fathead Minnows Exposed to Daily Varying Dose of Environmental Contaminants Individually and in Mixture.

Zare A, Henry D, Chua G, Gordon P, Habibi HR.

Front Endocrinol (Lausanne). 2018 Dec 10;9:749. doi: 10.3389/fendo.2018.00749. eCollection 2018.


Information sources and online information seeking behaviours of cancer patients in Singapore.

Chua GP, Tan HK, Gandhi M.

Ecancermedicalscience. 2018 Oct 31;12:880. doi: 10.3332/ecancer.2018.880. eCollection 2018.


What information do cancer patients want and how well are their needs being met?

Chua GP, Tan HK, Gandhi M.

Ecancermedicalscience. 2018 Sep 25;12:873. doi: 10.3332/ecancer.2018.873. eCollection 2018.


Exposure to naphthenic acids and the acid extractable organic fraction from oil sands process-affected water alters the subcellular structure and dynamics of plant cells.

Alberts ME, Chua G, Muench DG.

Sci Total Environ. 2019 Feb 15;651(Pt 2):2830-2844. doi: 10.1016/j.scitotenv.2018.10.181. Epub 2018 Oct 15.


Integrating complementary methods to improve diet analysis in fishery-targeted species.

Matley JK, Maes GE, Devloo-Delva F, Huerlimann R, Chua G, Tobin AJ, Fisk AT, Simpfendorfer CA, Heupel MR.

Ecol Evol. 2018 Aug 29;8(18):9503-9515. doi: 10.1002/ece3.4456. eCollection 2018 Sep.


Comparative efficacy of inhaled medications (ICS/LABA, LAMA, LAMA/LABA and SAMA) for COPD: a systematic review and network meta-analysis.

Aziz MIA, Tan LE, Wu DB, Pearce F, Chua GSW, Lin L, Tan PT, Ng K.

Int J Chron Obstruct Pulmon Dis. 2018 Oct 9;13:3203-3231. doi: 10.2147/COPD.S173472. eCollection 2018.


Hong Kong Institute of Allergy and Hong Kong Society for Paediatric Immunology Allergy & Infectious Diseases joint consensus statement 2018 on vaccination in egg-allergic patients.

Chua GT, Li PH, Ho MH, Lai E, Ngai V, Yau FY, Kwan MY, Leung TF, Lee TH.

Hong Kong Med J. 2018 Oct;24(5):527-531. doi: 10.12809/hkmj177137.


Long-Term Disease-Free Survival of a Patient with Oligometastatic Nasopharyngeal Carcinoma Treated with Radiotherapy Alone.

Chua GWY, Chua ET.

Case Rep Oncol. 2018 Jun 22;11(2):392-398. doi: 10.1159/000490236. eCollection 2018 May-Aug.


Using a Chemical Genetic Screen to Enhance Our Understanding of the Antibacterial Properties of Silver.

Gugala N, Lemire J, Chatfield-Reed K, Yan Y, Chua G, Turner RJ.

Genes (Basel). 2018 Jul 6;9(7). pii: E344. doi: 10.3390/genes9070344.


Impact of a pharmacy-led smoking cessation clinic in a dermatology centre.

Cheng HM, Liu WC, Chua G, Liew CF, Li W, Choo W, Oon HH.

Singapore Med J. 2019 Jan;60(1):31-33. doi: 10.11622/smedj.2018063. Epub 2018 May 18.


New therapeutic opportunities from dissecting the pre-B leukemia bone marrow microenvironment.

Cheung LC, Tickner J, Hughes AM, Skut P, Howlett M, Foley B, Oommen J, Wells JE, He B, Singh S, Chua GA, Ford J, Mullighan CG, Kotecha RS, Kees UR.

Leukemia. 2018 Nov;32(11):2326-2338. doi: 10.1038/s41375-018-0144-7. Epub 2018 May 8.


Effectiveness of a chronic obstructive pulmonary disease integrated care pathway in a regional health system: a propensity score matched cohort study.

Wu CX, Hwang CH, Tan WS, Tai KP, Kwek LSL, Chee TG, Choo YM, Phng FWL, Chua GSW.

BMJ Open. 2018 Mar 22;8(3):e019425. doi: 10.1136/bmjopen-2017-019425.


Ministry of Health Clinical Practice Guidelines: Chronic Obstructive Pulmonary Disease.

Lim TK, Chee CB, Chow P, Chua GSW, Eng SK, Goh SK, Kng KK, Lim WH, Ng TP, Ong TH, Seah STA, Tan HY, Tee KH, Palanichamy V, Yeung MT.

Singapore Med J. 2018 Feb;59(2):76-86. doi: 10.11622/smedj.2018015.


Size-selective purification of hepatitis B virus-like particle in flow-through chromatography: Types of ion exchange adsorbent and grafted polymer architecture.

Ng HW, Lee MFX, Chua GK, Gan BK, Tan WS, Ooi CW, Tang SY, Chan ES, Tey BT.

J Sep Sci. 2018 May;41(10):2119-2129. doi: 10.1002/jssc.201700823. Epub 2018 Mar 15.


Paediatric case series of drug reaction with eosinophilia and systemic symptoms (DRESS): 12-year experience at a single referral centre in Hong Kong and the first reported use of infliximab.

Chua GT, Rosa Duque JS, Chong PCY, Lee PPW, Lau YL, Ho MHK.

Eur Ann Allergy Clin Immunol. 2018 Nov;50(6):273-276. doi: 10.23822/EurAnnACI.1764-1489.47. Epub 2017 Nov 30.


Posterior Elbow Dislocation with Brachial Artery Thrombosis Treated Non-surgically: A Case Report.

Lim SM, Chua GG, Asrul F, Yazid M.

Malays Orthop J. 2017 Nov;11(3):63-65. doi: 10.5704/MOJ.1711.008.


Determination of Cost-Effectiveness Threshold for Health Care Interventions in Malaysia.

Lim YW, Shafie AA, Chua GN, Ahmad Hassali MA.

Value Health. 2017 Sep;20(8):1131-1138. doi: 10.1016/j.jval.2017.04.002. Epub 2017 Jun 2.


Assessing dose contribution to pelvic lymph nodes in intracavitary brachytherapy for cervical cancer.

Chua GWY, Foo YW, Tay GH, Tan DBH.

J Contemp Brachytherapy. 2017 Aug;9(4):345-353. doi: 10.5114/jcb.2017.69237. Epub 2017 Jul 27.


Embryonic exposure to model naphthenic acids delays growth and hatching in the pond snail Lymnaea stagnalis.

Johnston CU, Clothier LN, Quesnel DM, Gieg LM, Chua G, Hermann PM, Wildering WC.

Chemosphere. 2017 Feb;168:1578-1588. doi: 10.1016/j.chemosphere.2016.11.156. Epub 2016 Dec 5.


Stress and Burnout among Physicians: Prevalence and Risk Factors in a Singaporean Internal Medicine Programme.

See KC, Lim TK, Kua EH, Phua J, Chua GS, Ho KY.

Ann Acad Med Singapore. 2016 Oct;45(10):471-474. No abstract available.


Biological relevance of fatty acyl heterogeneity to the neural membrane dynamics of rhesus macaques during normative aging.

Lam SM, Chua GH, Li XJ, Su B, Shui G.

Oncotarget. 2016 Aug 30;7(35):55970-55989. doi: 10.18632/oncotarget.11190.


Identification of novel transcriptional regulators of PKA subunits in Saccharomyces cerevisiae by quantitative promoter-reporter screening.

Pautasso C, Reca S, Chatfield-Reed K, Chua G, Galello F, Portela P, Zaremberg V, Rossi S.

FEMS Yeast Res. 2016 Aug;16(5). pii: fow046. doi: 10.1093/femsyr/fow046. Epub 2016 May 11.


NMR Characterization and Membrane Interactions of the Loop Region of Kindlin-3 F1 Subdomain.

Chua GL, Tan SM, Bhattacharjya S.

PLoS One. 2016 Apr 21;11(4):e0153501. doi: 10.1371/journal.pone.0153501. eCollection 2016.


Conserved and Diverged Functions of the Calcineurin-Activated Prz1 Transcription Factor in Fission Yeast.

Chatfield-Reed K, Vachon L, Kwon EJ, Chua G.

Genetics. 2016 Apr;202(4):1365-75. doi: 10.1534/genetics.115.184218. Epub 2016 Feb 19.


Development of a low-serum medium for the production of monoclonal antibody against congenital adrenal hyperplasia by hybridoma culture.

Chua GK.

Prep Biochem Biotechnol. 2016 Oct 2;46(7):679-85. doi: 10.1080/10826068.2015.1135450.


Biostimulation of Oil Sands Process-Affected Water with Phosphate Yields Removal of Sulfur-Containing Organics and Detoxification.

Quesnel DM, Oldenburg TB, Larter SR, Gieg LM, Chua G.

Environ Sci Technol. 2015 Nov 3;49(21):13012-20. doi: 10.1021/acs.est.5b01391. Epub 2015 Oct 23.


Identification of detoxification pathways in plants that are regulated in response to treatment with organic compounds isolated from oil sands process-affected water.

Widdup EE, Chatfield-Reed K, Henry D, Chua G, Samuel MA, Muench DG.

Chemosphere. 2015 Nov;139:47-53. doi: 10.1016/j.chemosphere.2015.05.048. Epub 2015 Jun 5.


The NuA4 complex promotes translesion synthesis (TLS)-mediated DNA damage tolerance.

Renaud-Young M, Lloyd DC, Chatfield-Reed K, George I, Chua G, Cobb J.

Genetics. 2015 Apr;199(4):1065-76. doi: 10.1534/genetics.115.174490. Epub 2015 Feb 19.


A matched-group study protocol to evaluate the implementation of an Integrated Care Pathway programme for chronic obstructive pulmonary disease in Singapore.

Wu CX, Tan WS, See RC, Yu W, Kwek LS, Toh MP, Chee TG, Chua GS.

BMJ Open. 2015 Jan 7;5(1):e005655. doi: 10.1136/bmjopen-2014-005655.


When traditional model meets competencies in Singapore: beyond conflict resolution.

Khoo SM, Lahiri M, Huggan PJ, Archuleta S, Olszyna DP, Goh WP, Chua GS, Ho KY.

Ann Acad Med Singapore. 2014 Nov;43(11):544-9.


Exploring the willingness to pay for a quality-adjusted life-year in the state of Penang, Malaysia.

Shafie AA, Lim YW, Chua GN, Hassali MA.

Clinicoecon Outcomes Res. 2014 Oct 23;6:473-81. doi: 10.2147/CEOR.S67375. eCollection 2014.


Determination of Cost-Effectiveness Threshold For Malaysia.

Lim YW, Shafie AA, Chua GN, Hassali MA.

Value Health. 2014 Nov;17(7):A438. doi: 10.1016/j.jval.2014.08.1137. Epub 2014 Oct 26. No abstract available.


Job satisfaction, organisation commitment and retention in the public workforce: a survey among pharmacists in Malaysia.

Chua GN, Yee LJ, Sim BA, Tan KH, Sin NK, Hassali MA, Shafie AA, Ooi GS.

Int J Pharm Pract. 2014 Aug;22(4):265-74.


Aleukaemic leukaemia presenting with pathological fracture.

Chua GT, Chow KC, So JC, Cheuk DK.

BMJ Case Rep. 2014 Jul 2;2014. pii: bcr2014204690. doi: 10.1136/bcr-2014-204690.


Obesity and overweight management in malaysia and singapore: progress on right track.

Verma RK, Chua G, David SR.

J Clin Diagn Res. 2013 Dec;7(12):3124-5. doi: 10.7860/JCDR/2013/7860.3883. Epub 2013 Nov 25. No abstract available.


Systematic genetic analysis of transcription factors to map the fission yeast transcription-regulatory network.

Chua G.

Biochem Soc Trans. 2013 Dec;41(6):1696-700. doi: 10.1042/BST20130224. Review.


Measurement of LRRK2 and Ser910/935 phosphorylated LRRK2 in peripheral blood mononuclear cells from idiopathic Parkinson's disease patients.

Dzamko N, Chua G, Ranola M, Rowe DB, Halliday GM.

J Parkinsons Dis. 2013;3(2):145-52. doi: 10.3233/JPD-130174.


The effect of oil sands process-affected water and naphthenic acids on the germination and development of Arabidopsis.

Leishman C, Widdup EE, Quesnel DM, Chua G, Gieg LM, Samuel MA, Muench DG.

Chemosphere. 2013 Sep;93(2):380-7. doi: 10.1016/j.chemosphere.2013.04.101. Epub 2013 Jun 6.


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