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Bacterial burden in the lower airways predicts disease progression in idiopathic pulmonary fibrosis and is independent of radiological disease extent.

Invernizzi R, Barnett J, Rawal B, Nair A, Ghai P, Kingston S, Chua F, Wu Z, Wells AU, Renzoni ER, Nicholson AG, Rice A, Lloyd CM, Byrne AJ, Maher TM, Devaraj A, Molyneaux PL.

Eur Respir J. 2020 Jan 24. pii: 1901519. doi: 10.1183/13993003.01519-2019. [Epub ahead of print]


Images of the month 1: Cough before the storm: A case of pulmonary alveolar microlithiasis.

Yazdani MF, Morris-Rosendahl D, Chen L, Devaraj A, Chua F.

Clin Med (Lond). 2020 Jan;20(1):110-111. doi: 10.7861/clinmed.2019-0370. No abstract available.


Defining genetic risk factors for scleroderma-associated interstitial lung disease : IRF5 and STAT4 gene variants are associated with scleroderma while STAT4 is protective against scleroderma-associated interstitial lung disease.

Stock CJW, De Lauretis A, Visca D, Daccord C, Kokosi M, Kouranos V, Margaritopoulos G, George PM, Molyneaux PL, Nihtyanova S, Chua F, Maher TM, Ong V, Abraham DJ, Denton CP, Wells AU, Wain LV, Renzoni EA.

Clin Rheumatol. 2020 Jan 8. doi: 10.1007/s10067-019-04922-6. [Epub ahead of print]


Diffuse granulomatous disease: looking inside and outside the lungs.

Williams A, Kelleher WP, Nicholson AG, Devaraj A, Pavesio C, Chua F.

Thorax. 2020 Feb;75(2):189-191. doi: 10.1136/thoraxjnl-2019-213797. Epub 2020 Jan 6. No abstract available.


Familial lung disease presenting in reverse.

Mackintosh JA, Chua F.

Lancet Respir Med. 2019 Dec;7(12):1084. doi: 10.1016/S2213-2600(19)30403-5. No abstract available.


Physiological predictors of exertional oxygen desaturation in patients with fibrotic interstitial lung disease.

Alfieri V, Crisafulli E, Visca D, Chong WH, Stock C, Mori L, de Lauretis A, Tsipouri V, Chua F, Kouranos V, Kokosi M, Hogben C, Molyneaux PL, George PM, Maher TM, Chetta AA, Sestini P, Wells AU, Renzoni EA.

Eur Respir J. 2020 Feb 20;55(2). pii: 1901681. doi: 10.1183/13993003.01681-2019. Print 2020 Feb. No abstract available.


Pleuroparenchymal Fibroelastosis. A Review of Clinical, Radiological, and Pathological Characteristics.

Chua F, Desai SR, Nicholson AG, Devaraj A, Renzoni E, Rice A, Wells AU.

Ann Am Thorac Soc. 2019 Nov;16(11):1351-1359. doi: 10.1513/AnnalsATS.201902-181CME.


Right Ventricular to Left Ventricular Ratio at CT Pulmonary Angiogram Predicts Mortality in Interstitial Lung Disease.

Bax S, Jacob J, Ahmed R, Bredy C, Dimopoulos K, Kempny A, Kokosi M, Kier G, Renzoni E, Molyneaux PL, Chua F, Kouranos V, George P, McCabe C, Wilde M, Devaraj A, Wells A, Wort SJ, Price LC.

Chest. 2020 Jan;157(1):89-98. doi: 10.1016/j.chest.2019.06.033. Epub 2019 Jul 24.


The interaction between ionic liquids (ILs) and an enriched ammonia oxidising bacteria (AOB) culture.

Chua FJD, Yan W, Zhou Y.

Chemosphere. 2019 Nov;235:842-848. doi: 10.1016/j.chemosphere.2019.07.001. Epub 2019 Jul 3.


The role of ammonium oxidising bacteria (AOB) in ionic liquid 1-dodecylpyridinium chloride removal.

Chua FJD, Zhou Y.

Appl Microbiol Biotechnol. 2019 Jun;103(11):4595-4604. doi: 10.1007/s00253-019-09799-8. Epub 2019 Apr 11.


In patients with idiopathic pulmonary fibrosis the presence of hiatus hernia is associated with disease progression and mortality.

Mackintosh JA, Desai SR, Adamali H, Patel K, Chua F, Devaraj A, Kouranos V, Kokosi M, Margaritopoulos G, Renzoni EA, Wells AU, Molyneaux PL, Kumar S, Maher TM, George PM.

Eur Respir J. 2019 May 23;53(5). pii: 1802412. doi: 10.1183/13993003.02412-2018. Print 2019 May. No abstract available.


Clinical utility of existing and second-generation interferon-γ release assays for diagnostic evaluation of tuberculosis: an observational cohort study.

Whitworth HS, Badhan A, Boakye AA, Takwoingi Y, Rees-Roberts M, Partlett C, Lambie H, Innes J, Cooke G, Lipman M, Conlon C, Macallan D, Chua F, Post FA, Wiselka M, Woltmann G, Deeks JJ, Kon OM, Lalvani A; Interferon-γ Release Assays for Diagnostic Evaluation of Active Tuberculosis study group.

Lancet Infect Dis. 2019 Feb;19(2):193-202. doi: 10.1016/S1473-3099(18)30613-3. Epub 2019 Jan 14. Erratum in: Lancet Infect Dis. 2019 Feb;19(2):e39. Lancet Infect Dis. 2019 Mar;19(3):e64.


Free nitrous acid (FNA) induced transformation of sulfamethoxazole in the enriched nitrifying culture.

Sun F, Wu D, Chua FD, Zhu W, Zhou Y.

Water Res. 2019 Feb 1;149:432-439. doi: 10.1016/j.watres.2018.10.031. Epub 2018 Oct 13.


The potential impact of azithromycin in idiopathic pulmonary fibrosis.

Macaluso C, Maritano Furcada J, Alzaher O, Chaube R, Chua F, Wells AU, Maher TM, George PM, Renzoni EA, Molyneaux PL.

Eur Respir J. 2019 Feb 14;53(2). pii: 1800628. doi: 10.1183/13993003.00628-2018. Print 2019 Feb. No abstract available.


Safety and tolerability of nintedanib for the treatment of idiopathic pulmonary fibrosis in routine UK clinical practice.

Fletcher SV, Jones MG, Renzoni EA, Parfrey H, Hoyles RK, Spinks K, Kokosi M, Kwok A, Warburton C, Titmuss V, Thillai M, Simler N, Maher TM, Brereton CJ, Chua F, Wells AU, Richeldi L, Spencer LG.

ERJ Open Res. 2018 Oct 19;4(4). pii: 00049-2018. doi: 10.1183/23120541.00049-2018. eCollection 2018 Oct.


Effect of ambulatory oxygen on quality of life for patients with fibrotic lung disease (AmbOx): a prospective, open-label, mixed-method, crossover randomised controlled trial.

Visca D, Mori L, Tsipouri V, Fleming S, Firouzi A, Bonini M, Pavitt MJ, Alfieri V, Canu S, Bonifazi M, Boccabella C, De Lauretis A, Stock CJW, Saunders P, Montgomery A, Hogben C, Stockford A, Pittet M, Brown J, Chua F, George PM, Molyneaux PL, Margaritopoulos GA, Kokosi M, Kouranos V, Russell AM, Birring SS, Chetta A, Maher TM, Cullinan P, Hopkinson NS, Banya W, Whitty JA, Adamali H, Spencer LG, Farquhar M, Sestini P, Wells AU, Renzoni EA.

Lancet Respir Med. 2018 Oct;6(10):759-770. doi: 10.1016/S2213-2600(18)30289-3. Epub 2018 Aug 28.


Durable engraftment of genetically modified FVIII-secreting autologous bone marrow stromal cells in the intramedullary microenvironment.

Lee SS, Sivalingam J, Nirmal AJ, Ng WH, Kee I, Song IC, Kiong CY, Gales KA, Chua F, Pena EM, Ogden BE, Kon OL.

J Cell Mol Med. 2018 Jul;22(7):3698-3702. doi: 10.1111/jcmm.13648. Epub 2018 Apr 23.


Acute Trauma Coagulopathy: Prevalence and Impact on Outcomes of Trauma Patients Presenting to the Emergency Department.

Balasubramaniam S, Teo YX, Chua FH, Cheng JY, Teo LT.

Ann Acad Med Singapore. 2018 Feb;47(2):82-84. No abstract available.


Evaluating disease severity in idiopathic pulmonary fibrosis.

Robbie H, Daccord C, Chua F, Devaraj A.

Eur Respir Rev. 2017 Sep 6;26(145). pii: 170051. doi: 10.1183/16000617.0051-2017. Print 2017 Sep 30. Review.


Pleuroparenchymal Fibroelastosis: A Review of Histopathologic Features and the Relationship Between Histologic Parameters and Survival.

Khiroya R, Macaluso C, Montero MA, Wells AU, Chua F, Kokosi M, Maher TM, Devaraj A, Rice A, Renzoni EA, Nicholson AG.

Am J Surg Pathol. 2017 Dec;41(12):1683-1689. doi: 10.1097/PAS.0000000000000928.


Androgen receptor and miR-206 regulation in prostate cancer.

Chua FY, Adams BD.

Transcription. 2017;8(5):313-327. doi: 10.1080/21541264.2017.1322668. Epub 2017 Jun 9. Review.


Medulloblastoma with tri-vergent melanocytic, myogenic and cartiligious elements.

Chua FHZ, Low DCY, Lian DWQ, Ng LP, Chang KTE, Loh E, Seow WT, Low SYY.

J Clin Neurosci. 2017 Jul;41:100-103. doi: 10.1016/j.jocn.2017.03.030. Epub 2017 Mar 23. No abstract available.


Anomalous intracranial germinoma with unilateral cerebral peduncle swelling.

Chua FHZ, Low DCY, Lian DWQ, Tew SW, Low SYY.

Childs Nerv Syst. 2017 Apr;33(4):563-565. doi: 10.1007/s00381-017-3355-8. Epub 2017 Mar 10. No abstract available.


Post-operative diffusion weighted imaging as a predictor of posterior fossa syndrome permanence in paediatric medulloblastoma.

Chua FHZ, Thien A, Ng LP, Seow WT, Low DCY, Chang KTE, Lian DWQ, Loh E, Low SYY.

Childs Nerv Syst. 2017 Mar;33(3):457-465. doi: 10.1007/s00381-017-3356-7. Epub 2017 Feb 11.


Chemical composition and cytotoxic properties of Clinacanthus nutans root extracts.

Teoh PL, Cheng AY, Liau M, Lem FF, Kaling GP, Chua FN, Cheong BE.

Pharm Biol. 2017 Dec;55(1):394-401.


Patient eligibility for anti-fibrotic therapy in idiopathic pulmonary fibrosis can be altered by use of different sets of reference values for calculation of FVC percent predicted.

Ward K, Spurr L, Goldman NR, Margaritopoulos GA, Kokosi M, Renzoni E, Chua F, Maher TM, Ward S, Wells AU.

Respir Med. 2016 Nov;120:131-133. doi: 10.1016/j.rmed.2016.10.007. Epub 2016 Oct 14.


An emerging interstitial lung disease.

George PM, Devaraj A, Nicholson AG, Chua F.

Lancet Respir Med. 2016 Sep;4(9):762. doi: 10.1016/S2213-2600(16)30242-9. No abstract available.


Saccade plan overlap and cancellation during free viewing.

Wu EXW, Chua FK, Yen SC.

Vision Res. 2016 Oct;127:122-131. doi: 10.1016/j.visres.2016.07.009. Epub 2016 Aug 23.


Disseminated extracranial metastatic meningioma.

Chua FH, Low SY, Tham CK, Ding C, Wong CF, Nolan CP.

J Clin Neurosci. 2016 Nov;33:214-216. doi: 10.1016/j.jocn.2016.01.038. Epub 2016 Aug 8.


Nitric oxide treatment for the control of reverse osmosis membrane biofouling.

Barnes RJ, Low JH, Bandi RR, Tay M, Chua F, Aung T, Fane AG, Kjelleberg S, Rice SA.

Appl Environ Microbiol. 2015 Apr;81(7):2515-24. doi: 10.1128/AEM.03404-14. Epub 2015 Jan 30.


A moving overlay shrinks the attentional blink.

Chua FK.

Atten Percept Psychophys. 2015 Jan;77(1):173-89. doi: 10.3758/s13414-014-0753-9.


Attentional capture by dynamic cues.

Chua FK.

Atten Percept Psychophys. 2015 Jan;77(1):111-27. doi: 10.3758/s13414-014-0759-3.


Children must be protected from the tobacco industry's marketing tactics.

Hopkinson N, Wallis C, Higgins B, Gaduzo S, Sherrington R, Keilty S, Stern M, Britton J, Bush A, Moxham J, Sylvester K, Griffiths V, Sutherland T, Crossingham I, Raju R, Spencer C, Safavi S, Deegan P, Seymour J, Hickman K, Hughes J, Wieboldt J, Shaheen F, Peedell C, Mackenzie N, Nicholl D, Jolley C, Crooks G, Crooks G, Dow C, Deveson P, Bintcliffe O, Gray B, Kumar S, Haney S, Docherty M, Thomas A, Chua F, Dwarakanath A, Summers G, Prowse K, Lytton S, Ong YE, Graves J, Banerjee T, English P, Leonard A, Brunet M, Chaudhry N, Ketchell RI, Cummings N, Lebus J, Sharp C, Meadows C, Harle A, Stewart T, Parry D, Templeton-Wright S, Moore-Gillon J, Stratford- Martin J, Saini S, Matusiewicz S, Merritt S, Dowson L, Satkunam K, Hodgson L, Suh ES, Durrington H, Browne E, Walters N, Steier J, Barry S, Griffiths M, Hart N, Nikolic M, Berry M, Thomas A, Miller J, McNicholl D, Marsden P, Warwick G, Barr L, Adeboyeku D, Mohd Noh MS, Griffiths P, Davies L, Quint J, Lyall R, Shribman J, Collins A, Goldman J, Bloch S, Gill A, Man W, Christopher A, Yasso R, Rajhan A, Shrikrishna D, Moore C, Absalom G, Booton R, Fowler RW, Mackinlay C, Sapey E, Lock S, Walker P, Jha A, Satia I, Bradley B, Mustfa N, Haqqee R, Thomas M, Patel A, Redington A, Pillai A, Keaney N, Fowler S, Lowe L, Brennan A, Morrison D, Murray C, Hankinson J, Dutta P, Maddocks M, Pengo M, Curtis K, Rafferty G, Hutchinson J, Whitfield R, Turner S, Breen R, Naveed SU, Goode C, Esterbrook G, Ahmed L, Walker W, Ford D, Connett G, Davidson P, Elston W, Stanton A, Morgan D, Myerson J, Maxwell D, Harrris A, Parmar S, Houghton C, Winter R, Puthucheary Z, Thomson F, Sturney S, Harvey J, Haslam PL, Patel I, Jennings D, Range S, Mallia-Milanes B, Collett A, Tate P, Russell R, Feary J, O'Driscoll R, Eaden J, Round J, Sharkey E, Montgomery M, Vaughan S, Scheele K, Lithgow A, Partridge S, Chavasse R, Restrick L, Agrawal S, Abdallah S, Lacy-Colson A, Adams N, Mitchell S, Haja Mydin H, Ward A, Denniston S, Steel M, Ghosh D, Connellan S, Rigge L, Williams R, Grove A, Anwar S, Dobson L, Hosker H, Stableforth D, Greening N, Howell T, Casswell G, Davies S, Tunnicliffe G, Mitchelmore P, Phitidis E, Robinson L, Prowse K, Bafadhel M, Robinson G, Boland A, Lipman M, Bourke S, Kaul S, Cowie C, Forrest I, Starren E, Burke H, Furness J, Bhowmik A, Everett C, Seaton D, Holmes S, Doe S, Parker S, Graham A, Paterson I, Maqsood U, Ohri C, Iles P, Kemp S, Iftikhar A, Carlin C, Fletcher T, Emerson P, Beasley V, Ramsay M, Buttery R, Mungall S, Crooks S, Ridyard J, Ross D, Guadagno A, Holden E, Coutts I, Cullen K, O'Connor S, Barker J, Sloper K, Watson J, Smith P, Anderson P, Brown L, Nyman C, Milburn H, Clive A, Serlin M, Bolton C, Fuld J, Powell H, Dayer M, Woolhouse I, Georgiadi A, Leonard H, Dodd J, Campbell I, Ruiz G, Zurek A, Paton JY, Malin A, Wood F, Hynes G, Connell D, Spencer D, Brown S, Smith D, Cooper D, O'Kane C, Hicks A, Creagh-Brown B, Lordan J, Nickol A, Primhak R, Fleming L, Powrie D, Brown J, Zoumot Z, Elkin S, Szram J, Scaffardi A, Marshall R, Macdonald I, Lightbody D, Farmer R, Wheatley I, Radnan P, Lane I, Booth A, Tilbrook S, Capstick T, Hewitt L, McHugh M, Nelson C, Wilson P, Padmanaban V, White J, Davison J, O'Callaghan U, Hodson M, Edwards J, Campbell C, Ward S, Wooler E, Ringrose E, Bridges D, Matthew Hodson, John Edwards, Colin Campbell, Simon Ward, Edwina Wooler, Elizabeth Ringrose, Diana Bridges, Rosalind Backham, Kim Randall, Tracey Mathieson, Long A, Parkes M, Clarke S, Allen B, Connelly C, Forster G, Hoadley J, Martin K, Barnham K, Khan K, Munday M, Edwards C, O'Hara D, Turner S, Pieri-Davies S, Ford K, Daniels T, Wright J, Towns R, Fern K, Butcher J, Burgin K, Winter B, Freeman D, Olive S, Gray L, Pye K, Roots D, Cox N, Davies CA, Wicker J, Hilton K, Lloyd J, MacBean V, Wood M, Kowal J, Downs J, Ryan H, Guyatt F, Nicoll D, Lyons E, Narasimhan D, Rodman A, Walmsley S, Newey A, Buxton M, Dewar M, Cooper A, Reilly J, Lloyd J, Macmillan AB, Roots D, Olley A, Voase N, Martin S, McCarvill I, Christensen A, Agate R, Heslop K, Timlett A, Hailes K, Davey C, Pawulska B, Lane A, Ioakim S, Hough A, Treharne J, Jones H, Winter-Burke A, Miller L, Connolly B, Bingham L, Fraser U, Bott J, Johnston C, Graham A, Curry D, Sumner H, Costello CA, Bartoszewicz C, Badman R, Williamson K, Taylor A, Purcell H, Barnett E, Molloy A, Crawfurd L, Collins N, Monaghan V, Mir M, Lord V, Stocks J, Edwards A, Greenhalgh T, Lenney W, McKee M, McAuley D, Majeed A, Cookson J, Baker E, Janes S, Wedzicha W, Lomas Dean D, Harrison B, Davison T, Calverley P, Wilson R, Stockley R, Ayres J, Gibson J, Simpson J, Burge S, Warner J, Lenney W, Thomson N, Davies P, Woodcock A, Woodhead M, Spiro S, Ormerod L, Bothamley G, Partridge M, Shields M, Montgomery H, Simonds A, Barnes P, Durham S, Malone S, Arabnia G, Olivier S, Gardiner K, Edwards S.

BMJ. 2013 Dec 9;347:f7358. doi: 10.1136/bmj.f7358. No abstract available.


Parallel programming of saccades during natural scene viewing: evidence from eye movement positions.

Wu EX, Gilani SO, van Boxtel JJ, Amihai I, Chua FK, Yen SC.

J Vis. 2013 Oct 24;13(12):17. doi: 10.1167/13.12.17.


Interstitial lung disease in inflammatory myopathies: clinical phenotypes and prognosis.

Kiely PD, Chua F.

Curr Rheumatol Rep. 2013 Sep;15(9):359. doi: 10.1007/s11926-013-0359-6. Review.


Airway and parenchymal manifestations of pulmonary aspergillosis.

Tunnicliffe G, Schomberg L, Walsh S, Tinwell B, Harrison T, Chua F.

Respir Med. 2013 Aug;107(8):1113-23. doi: 10.1016/j.rmed.2013.03.016. Epub 2013 May 20. Review.


Spontaneous pneumothorax in a 50-year-old man with diffuse pulmonary nodules.

Stolagiewicz N, Tinwel B, Cormack IS, Lucas SB, Devaraj A, Kay-Loke T, Chua F.

Chest. 2013 Apr;143(4):1174-1179. doi: 10.1378/chest.12-0633. No abstract available.


An unusual cause of cyanosis in a patient with COPD.

Chang YJ, Ali H, Draper A, Chua F.

BMJ Case Rep. 2013 Mar 1;2013. pii: bcr2012008092. doi: 10.1136/bcr-2012-008092.


Tuning characteristics of the top-down attentional setting.

Chua FK.

Atten Percept Psychophys. 2013 Apr;75(3):440-55. doi: 10.3758/s13414-012-0414-9.


Multidetector CT and postprocessing in planning and assisting in minimally invasive bronchoscopic airway interventions.

Nair A, Godoy MC, Holden EL, Madden BP, Chua F, Ost DE, Roos JE, Naidich DP, Vlahos I.

Radiographics. 2012 Sep-Oct;32(5):E201-32. doi: 10.1148/rg.325115133. Review.


Idiopathic inflammatory myositis-associated interstitial lung disease: ethnicity differences and lung function trends in a British cohort.

Chua F, Higton AM, Colebatch AN, O'Reilly K, Grubnic S, Vlahos I, Edwards CJ, Kiely PD.

Rheumatology (Oxford). 2012 Oct;51(10):1870-6. Epub 2012 Jul 4.


Rituximab associated pneumonitis in antineutrophil cytoplasmic antibody-associated vasculitis.

Arulkumaran N, Suleman R, Cecconi M, Kiely P, Chua F.

J Clin Rheumatol. 2012 Jan;18(1):39-41. doi: 10.1097/RHU.0b013e31823ee5bf.


Effect of blast exposure on the brain structure and cognition in Macaca fascicularis.

Lu J, Ng KC, Ling G, Wu J, Poon DJ, Kan EM, Tan MH, Wu YJ, Li P, Moochhala S, Yap E, Lee LK, Teo M, Yeh IB, Sergio DM, Chua F, Kumar SD, Ling EA.

J Neurotrauma. 2012 May 1;29(7):1434-54. doi: 10.1089/neu.2010.1591. Epub 2011 Nov 7.


Chronic Pneumocystis jiroveci presenting as asymptomatic granulomatous pulmonary nodules in lymphoma.

Kumar N, Bazari F, Rhodes A, Chua F, Tinwell B.

J Infect. 2011 Jun;62(6):484-6. doi: 10.1016/j.jinf.2011.04.008. Epub 2011 Apr 27.


The European Working Time Directive and training.

Chua F.

Clin Med (Lond). 2011 Feb;11(1):98; author reply 98. No abstract available.


A new object captures attention--but only when you know which objects are old.

Chua FK.

Atten Percept Psychophys. 2011 Apr;73(3):797-808. doi: 10.3758/s13414-010-0066-6.


Passive stiffness of myocardium from congenital heart disease and implications for diastole.

Chaturvedi RR, Herron T, Simmons R, Shore D, Kumar P, Sethia B, Chua F, Vassiliadis E, Kentish JC.

Circulation. 2010 Mar 2;121(8):979-88. doi: 10.1161/CIRCULATIONAHA.109.850677. Epub 2010 Feb 16.


Positive predictive value of the UK clinical case definition for H1N1/09 ('swine') influenza.

Bicanic T, Solomon AW, Karunaharan N, Chua F, Pope C, Pond M, Herman J, Loyse A, Harrison T, Wansbrough-Jones M.

J Infect. 2010 May;60(5):405-7. doi: 10.1016/j.jinf.2010.02.001. Epub 2010 Feb 7. No abstract available.


Investigation of the patient with pleural effusion.

Chua F, Groth J.

Clin Med (Lond). 2009 Aug;9(4):400; author reply 401. No abstract available.

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