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Loganin prevents chronic constriction injury-provoked neuropathic pain by reducing TNF-α/IL-1β-mediated NF-κB activation and Schwann cell demyelination.

Chu LW, Cheng KI, Chen JY, Cheng YC, Chang YC, Yeh JL, Hsu JH, Dai ZK, Wu BN.

Phytomedicine. 2019 Dec 30;67:153166. doi: 10.1016/j.phymed.2019.153166. [Epub ahead of print]


TIM-1 As a Signal Receptor Triggers Dengue Virus-Induced Autophagy.

Chu LW, Yang CJ, Peng KJ, Chen PL, Wang SJ, Ping YH.

Int J Mol Sci. 2019 Oct 2;20(19). pii: E4893. doi: 10.3390/ijms20194893.


Chinese patients with Lewy body dementia had shorter survival and developed complications earlier than those with Alzheimer's disease.

Shea YF, Lee SC, Shum ACK, Chiu PK, Chu LW, Chan HWF.

Singapore Med J. 2019 Sep 6. doi: 10.11622/smedj.2019103. [Epub ahead of print]


Souvenaid in the management of mild cognitive impairment: an expert consensus opinion.

Cummings J, Passmore P, McGuinness B, Mok V, Chen C, Engelborghs S, Woodward M, Manzano S, Garcia-Ribas G, Cappa S, Bertolucci P, Chu LW.

Alzheimers Res Ther. 2019 Aug 17;11(1):73. doi: 10.1186/s13195-019-0528-6. Review.


Quality indicators on infection control in residential care homes for the elderly in Hong Kong.

Chu LW.

Hong Kong Med J. 2019 Apr;25(2):92-93. doi: 10.12809/hkmj195087. No abstract available.


Hyperphagia in Alzheimer's disease, its transient nature, and potentially reversible causes.

Leung WC, Shea YF, Lee SC, Chu LW.

Psychogeriatrics. 2019 Nov;19(6):619-621. doi: 10.1111/psyg.12432. Epub 2019 Feb 27. No abstract available.


Valproate reduces neuroinflammation and neuronal death in a rat chronic constriction injury model.

Chen JY, Chu LW, Cheng KI, Hsieh SL, Juan YS, Wu BN.

Sci Rep. 2018 Nov 7;8(1):16457. doi: 10.1038/s41598-018-34915-5.


Prevalence and risk factors of delirium and subsyndromal delirium in Chinese older adults.

Yam KK, Shea YF, Chan TC, Chiu KC, Luk JK, Chu LW, Chan FH.

Geriatr Gerontol Int. 2018 Dec;18(12):1625-1628. doi: 10.1111/ggi.13545. Epub 2018 Oct 12.


Self-Care Peritoneal Dialysis Patients with Cognitive Impairment Have a Higher Risk of Peritonitis in the Second Year.

Shea YF, Lee MC, Mok MM, Lam MF, Chu LW, Chan FH, Chan TM.

Perit Dial Int. 2019 Jan-Feb;39(1):51-58. doi: 10.3747/pdi.2018.00048. Epub 2018 Aug 7.


Auditory-based cognitive training programme for attention and memory in older people at risk of progressive cognitive decline: a randomised controlled trial.

Lee TM, Chan FH, Chu LW, Kwok TC, Lam LC, Tam HM, Woo J.

Hong Kong Med J. 2017 Jun;23 Suppl 2(3):12-15. No abstract available.


Metabolomic profiles in breast cancer:a pilot case-control study in the breast cancer family registry.

Dougan MM, Li Y, Chu LW, Haile RW, Whittemore AS, Han SS, Moore SC, Sampson JN, Andrulis IL, John EM, Hsing AW.

BMC Cancer. 2018 May 5;18(1):532. doi: 10.1186/s12885-018-4437-z.


A rare variant in MLKL confers susceptibility to ApoE ɛ4-negative Alzheimer's disease in Hong Kong Chinese population.

Wang B, Bao S, Zhang Z, Zhou X, Wang J, Fan Y, Zhang Y, Li Y, Chen L, Jia Y, Li J, Li M, Zheng W, Mu N, Wang L, Yu Z, Wong DSM, Zhang Y, Kwan J, Ka-Fung Mak H, Ambalavanan A, Zhou S, Cai W, Zheng J, Huang S, Rouleau GA, Yang W, Rogaeva E, Ma X, St George-Hyslop P, Chu LW, Song YQ.

Neurobiol Aging. 2018 Aug;68:160.e1-160.e7. doi: 10.1016/j.neurobiolaging.2018.03.006. Epub 2018 Mar 10.


Measuring serum melatonin in postmenopausal women: Implications for epidemiologic studies and breast cancer studies.

Chu LW, John EM, Yang B, Kurian AW, Zia Y, Yu K, Ingles SA, Stanczyk FZ, Hsing AW.

PLoS One. 2018 Apr 11;13(4):e0195666. doi: 10.1371/journal.pone.0195666. eCollection 2018.


Effectiveness of interventions for co-residing family caregivers of people with dementia: Systematic review and meta-analysis.

Abrahams R, Liu KPY, Bissett M, Fahey P, Cheung KSL, Bye R, Chaudhary K, Chu LW.

Aust Occup Ther J. 2018 Jun;65(3):208-224. doi: 10.1111/1440-1630.12464. Epub 2018 Mar 12.


Prevalence of hyperphagia in Alzheimer's disease: a meta-analysis.

Shea YF, Lee SC, Chu LW.

Psychogeriatrics. 2018 Jul;18(4):243-251. doi: 10.1111/psyg.12316. Epub 2018 Feb 6.


Circadian genes and risk of prostate cancer in the prostate cancer prevention trial.

Chu LW, Till C, Yang B, Tangen CM, Goodman PJ, Yu K, Zhu Y, Han S, Hoque AM, Ambrosone C, Thompson I, Leach R, Hsing AW.

Mol Carcinog. 2018 Mar;57(3):462-466. doi: 10.1002/mc.22770. Epub 2018 Jan 12.


Challenges in the diagnosis and management of dementia in Hong Kong.

Chu LW.

Hong Kong Med J. 2017 Jun;23(3):218-9. doi: 10.12809/hkmj175066. No abstract available.


A descriptive study of Lewy body dementia with functional imaging support in a Chinese population: a preliminary study.

Shea YF, Chu LW, Lee SC.

Hong Kong Med J. 2017 Jun;23(3):222-30. doi: 10.12809/hkmj166023. Epub 2017 May 5.


Association between high cumulative dose of benzodiazepine in Chinese patients and risk of dementia: a preliminary retrospective case-control study.

Chan TT, Leung WC, Li V, Wong KW, Chu WM, Leung KC, Ng YZ, Kai YG, Shea YF, Chang SR, Chu LW.

Psychogeriatrics. 2017 Sep;17(5):310-316. doi: 10.1111/psyg.12239. Epub 2017 Feb 1.


Genetic Polymorphisms in Estrogen Metabolic Pathway Associated with Risks of Alzheimer's Disease: Evidence from a Southern Chinese Population.

Chen LH, Fan YH, Kao PY, Ho DT, Ha JC, Chu LW, Song YQ.

J Am Geriatr Soc. 2017 Feb;65(2):332-339. doi: 10.1111/jgs.14537. Epub 2017 Jan 19.


Novel presenilin 1 mutation (p.F386I) in a Chinese family with early-onset Alzheimer's disease.

Shea YF, Chan AO, Chu LW, Lee SC, Law CY, See CH, Yiu KL, Chiu PK.

Neurobiol Aging. 2017 Feb;50:168.e9-168.e11. doi: 10.1016/j.neurobiolaging.2016.10.015. Epub 2016 Oct 15.


Sleep Duration and Cancer in the NIH-AARP Diet and Health Study Cohort.

Gu F, Xiao Q, Chu LW, Yu K, Matthews CE, Hsing AW, Caporaso NE.

PLoS One. 2016 Sep 9;11(9):e0161561. doi: 10.1371/journal.pone.0161561. eCollection 2016.


Neuroleptic Malignant Syndrome Caused by Quetiapine in an Elderly Man with Lewy Body Dementia.

Shea YF, Chu LW.

J Am Geriatr Soc. 2016 Sep;64(9):e55-6. doi: 10.1111/jgs.14184. Epub 2016 Aug 26. No abstract available.


Impact of (18)FDG PET and (11)C-PIB PET brain imaging on the diagnosis of Alzheimer's disease and other dementias in a regional memory clinic in Hong Kong.

Shea YF, Ha J, Lee SC, Chu LW.

Hong Kong Med J. 2016 Aug;22(4):327-33. doi: 10.12809/hkmj154707. Epub 2016 Jun 17.


Prevalence of Cognitive Impairment Among Peritoneal Dialysis Patients, Impact on Peritonitis and Role of Assisted Dialysis.

Shea YF, Lam MF, Lee MS, Mok MY, Lui SL, Yip TP, Lo WK, Chu LW, Chan TM.

Perit Dial Int. 2016 May-Jun;36(3):284-90. doi: 10.3747/pdi.2014.00247. Epub 2015 Dec 3.


A lucky and reversible cause of 'ischaemic bowel'.

Shea YF, Chow FC, Chan F, Ip JJ, Chiu PK, Chan FS, Chu LW.

Hong Kong Med J. 2015 Oct;21(5):471-4. doi: 10.12809/hkmj144306.


Neural Plastic Effects of Cognitive Training on Aging Brain.

Leung NT, Tam HM, Chu LW, Kwok TC, Chan F, Lam LC, Woo J, Lee TM.

Neural Plast. 2015;2015:535618. doi: 10.1155/2015/535618. Epub 2015 Aug 31.


A systematic review of familial Alzheimer's disease: Differences in presentation of clinical features among three mutated genes and potential ethnic differences.

Shea YF, Chu LW, Chan AO, Ha J, Li Y, Song YQ.

J Formos Med Assoc. 2016 Feb;115(2):67-75. doi: 10.1016/j.jfma.2015.08.004. Epub 2015 Aug 31. Review.


Intracellular Transport of Vaccinia Virus in HeLa Cells Requires WASH-VPEF/FAM21-Retromer Complexes and Recycling Molecules Rab11 and Rab22.

Hsiao JC, Chu LW, Lo YT, Lee SP, Chen TJ, Huang CY, Ping YH, Chang W.

J Virol. 2015 Aug;89(16):8365-82. doi: 10.1128/JVI.00209-15. Epub 2015 Jun 3.


Prevalence of CMMSE defined cognitive impairment among peritoneal dialysis patients and its impact on peritonitis.

Shea YF, Lam MF, Lee MS, Mok MY, Lui SL, Yip TP, Lo WK, Chu LW, Chan TM.

Clin Exp Nephrol. 2016 Feb;20(1):126-33. doi: 10.1007/s10157-015-1127-x. Epub 2015 May 21.


Atorvastatin prevents neuroinflammation in chronic constriction injury rats through nuclear NFκB downregulation in the dorsal root ganglion and spinal cord.

Chu LW, Chen JY, Wu PC, Wu BN.

ACS Chem Neurosci. 2015 Jun 17;6(6):889-98. doi: 10.1021/acschemneuro.5b00032. Epub 2015 Apr 21.


Delayed diagnosis of an old Chinese woman with familial Alzheimer's disease.

Shea YF, Chu LW, Chan AO, Kwan JS.

J Formos Med Assoc. 2015 Oct;114(10):1020-1. doi: 10.1016/j.jfma.2014.11.003. Epub 2015 Jan 26. No abstract available.


Validation of AD-CSF-Index in Chinese patients with Alzheimer's disease and nondemented controls.

Chu LW, Shea YF, Ha J.

Am J Alzheimers Dis Other Demen. 2015 Aug;30(5):522-6. doi: 10.1177/1533317514567126. Epub 2015 Jan 14.


Non-steroidal anti-inflammatory drugs use is associated with reduced risk of inflammation-associated cancers: NIH-AARP study.

Shebl FM, Hsing AW, Park Y, Hollenbeck AR, Chu LW, Meyer TE, Koshiol J.

PLoS One. 2014 Dec 31;9(12):e114633. doi: 10.1371/journal.pone.0114633. eCollection 2014.


Progressive supranuclear palsy presenting initially as semantic dementia.

Shea YF, Ha J, Chu LW.

J Am Geriatr Soc. 2014 Dec;62(12):2459-60. doi: 10.1111/jgs.13145. No abstract available.


Glial reaction in the spinal cord of the degenerating muscle mouse (Scn8a (dmu)).

Sato T, Fujita M, Shimizu Y, Kanetaka H, Chu LW, Côté PD, Ichikawa H.

Neurochem Res. 2015 Jan;40(1):124-9. doi: 10.1007/s11064-014-1475-z. Epub 2014 Nov 8.


Visual field defect as an uncommon presentation of posterior cortical atrophy.

Shea YF, Chu LW.

Geriatr Gerontol Int. 2014 Oct;14(4):1003-4. doi: 10.1111/ggi.12203. No abstract available.


Response to comments on "immunogenicity and safety of intradermal trivalent influenza vaccination in nursing home older adults: a randomized controlled trial".

Chan TC, Hung IF, Chan KH, Li CP, Li PT, Luk JK, Chu LW, Chan FH.

J Am Med Dir Assoc. 2014 Oct;15(10):773-4. doi: 10.1016/j.jamda.2014.07.014. No abstract available.


Relationship between male pattern baldness and the risk of aggressive prostate cancer: an analysis of the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial.

Zhou CK, Pfeiffer RM, Cleary SD, Hoffman HJ, Levine PH, Chu LW, Hsing AW, Cook MB.

J Clin Oncol. 2015 Feb 10;33(5):419-25. doi: 10.1200/JCO.2014.55.4279. Epub 2014 Sep 15.


Rapidly progressive ataxia during rehabilitation and a difficult road to diagnosis.

Shea YF, Chan TC, Chang RS, Hon FK, Kwan JS, Chu LW.

J Am Geriatr Soc. 2014 Aug;62(8):1609-10. doi: 10.1111/jgs.12955. No abstract available.


Protective effects of testosterone on presynaptic terminals against oligomeric β-amyloid peptide in primary culture of hippocampal neurons.

Lau CF, Ho YS, Hung CH, Wuwongse S, Poon CH, Chiu K, Yang X, Chu LW, Chang RC.

Biomed Res Int. 2014;2014:103906. doi: 10.1155/2014/103906. Epub 2014 Jun 18.


Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33.

Wang Z, Zhu B, Zhang M, Parikh H, Jia J, Chung CC, Sampson JN, Hoskins JW, Hutchinson A, Burdette L, Ibrahim A, Hautman C, Raj PS, Abnet CC, Adjei AA, Ahlbom A, Albanes D, Allen NE, Ambrosone CB, Aldrich M, Amiano P, Amos C, Andersson U, Andriole G Jr, Andrulis IL, Arici C, Arslan AA, Austin MA, Baris D, Barkauskas DA, Bassig BA, Beane Freeman LE, Berg CD, Berndt SI, Bertazzi PA, Biritwum RB, Black A, Blot W, Boeing H, Boffetta P, Bolton K, Boutron-Ruault MC, Bracci PM, Brennan P, Brinton LA, Brotzman M, Bueno-de-Mesquita HB, Buring JE, Butler MA, Cai Q, Cancel-Tassin G, Canzian F, Cao G, Caporaso NE, Carrato A, Carreon T, Carta A, Chang GC, Chang IS, Chang-Claude J, Che X, Chen CJ, Chen CY, Chen CH, Chen C, Chen KY, Chen YM, Chokkalingam AP, Chu LW, Clavel-Chapelon F, Colditz GA, Colt JS, Conti D, Cook MB, Cortessis VK, Crawford ED, Cussenot O, Davis FG, De Vivo I, Deng X, Ding T, Dinney CP, Di Stefano AL, Diver WR, Duell EJ, Elena JW, Fan JH, Feigelson HS, Feychting M, Figueroa JD, Flanagan AM, Fraumeni JF Jr, Freedman ND, Fridley BL, Fuchs CS, Gago-Dominguez M, Gallinger S, Gao YT, Gapstur SM, Garcia-Closas M, Garcia-Closas R, Gastier-Foster JM, Gaziano JM, Gerhard DS, Giffen CA, Giles GG, Gillanders EM, Giovannucci EL, Goggins M, Gokgoz N, Goldstein AM, Gonzalez C, Gorlick R, Greene MH, Gross M, Grossman HB, Grubb R 3rd, Gu J, Guan P, Haiman CA, Hallmans G, Hankinson SE, Harris CC, Hartge P, Hattinger C, Hayes RB, He Q, Helman L, Henderson BE, Henriksson R, Hoffman-Bolton J, Hohensee C, Holly EA, Hong YC, Hoover RN, Hosgood HD 3rd, Hsiao CF, Hsing AW, Hsiung CA, Hu N, Hu W, Hu Z, Huang MS, Hunter DJ, Inskip PD, Ito H, Jacobs EJ, Jacobs KB, Jenab M, Ji BT, Johansen C, Johansson M, Johnson A, Kaaks R, Kamat AM, Kamineni A, Karagas M, Khanna C, Khaw KT, Kim C, Kim IS, Kim JH, Kim YH, Kim YC, Kim YT, Kang CH, Jung YJ, Kitahara CM, Klein AP, Klein R, Kogevinas M, Koh WP, Kohno T, Kolonel LN, Kooperberg C, Kratz CP, Krogh V, Kunitoh H, Kurtz RC, Kurucu N, Lan Q, Lathrop M, Lau CC, Lecanda F, Lee KM, Lee MP, Le Marchand L, Lerner SP, Li D, Liao LM, Lim WY, Lin D, Lin J, Lindstrom S, Linet MS, Lissowska J, Liu J, Ljungberg B, Lloreta J, Lu D, Ma J, Malats N, Mannisto S, Marina N, Mastrangelo G, Matsuo K, McGlynn KA, McKean-Cowdin R, McNeill LH, McWilliams RR, Melin BS, Meltzer PS, Mensah JE, Miao X, Michaud DS, Mondul AM, Moore LE, Muir K, Niwa S, Olson SH, Orr N, Panico S, Park JY, Patel AV, Patino-Garcia A, Pavanello S, Peeters PH, Peplonska B, Peters U, Petersen GM, Picci P, Pike MC, Porru S, Prescott J, Pu X, Purdue MP, Qiao YL, Rajaraman P, Riboli E, Risch HA, Rodabough RJ, Rothman N, Ruder AM, Ryu JS, Sanson M, Schned A, Schumacher FR, Schwartz AG, Schwartz KL, Schwenn M, Scotlandi K, Seow A, Serra C, Serra M, Sesso HD, Severi G, Shen H, Shen M, Shete S, Shiraishi K, Shu XO, Siddiq A, Sierrasesumaga L, Sierri S, Loon Sihoe AD, Silverman DT, Simon M, Southey MC, Spector L, Spitz M, Stampfer M, Stattin P, Stern MC, Stevens VL, Stolzenberg-Solomon RZ, Stram DO, Strom SS, Su WC, Sund M, Sung SW, Swerdlow A, Tan W, Tanaka H, Tang W, Tang ZZ, Tardon A, Tay E, Taylor PR, Tettey Y, Thomas DM, Tirabosco R, Tjonneland A, Tobias GS, Toro JR, Travis RC, Trichopoulos D, Troisi R, Truelove A, Tsai YH, Tucker MA, Tumino R, Van Den Berg D, Van Den Eeden SK, Vermeulen R, Vineis P, Visvanathan K, Vogel U, Wang C, Wang C, Wang J, Wang SS, Weiderpass E, Weinstein SJ, Wentzensen N, Wheeler W, White E, Wiencke JK, Wolk A, Wolpin BM, Wong MP, Wrensch M, Wu C, Wu T, Wu X, Wu YL, Wunder JS, Xiang YB, Xu J, Yang HP, Yang PC, Yatabe Y, Ye Y, Yeboah ED, Yin Z, Ying C, Yu CJ, Yu K, Yuan JM, Zanetti KA, Zeleniuch-Jacquotte A, Zheng W, Zhou B, Mirabello L, Savage SA, Kraft P, Chanock SJ, Yeager M, Landi MT, Shi J, Chatterjee N, Amundadottir LT.

Hum Mol Genet. 2014 Dec 15;23(24):6616-33. doi: 10.1093/hmg/ddu363. Epub 2014 Jul 15.


Variants in motilin, somatostatin and their receptor genes and risk of biliary tract cancers and stones in Shanghai, China.

Xu HL, Hsing AW, Koshiol J, Chu LW, Cheng JR, Gao J, Tan YT, Wang BS, Shen MC, Gao YT.

Meta Gene. 2014 Dec 1;2:418-426.


Immunogenicity and safety of intradermal trivalent influenza vaccination in nursing home older adults: a randomized controlled trial.

Chan TC, Hung IF, Chan KH, Li CP, Li PT, Luk JK, Chu LW, Chan FH.

J Am Med Dir Assoc. 2014 Aug;15(8):607.e5-12. doi: 10.1016/j.jamda.2014.05.002. Epub 2014 Jun 21.


High prevalence of screen detected prostate cancer in West Africans: implications for racial disparity of prostate cancer.

Hsing AW, Yeboah E, Biritwum R, Tettey Y, De Marzo AM, Adjei A, Netto GJ, Yu K, Li Y, Chokkalingam AP, Chu LW, Chia D, Partin A, Thompson IM, Quraishi SM, Niwa S, Tarone R, Hoover RN.

J Urol. 2014 Sep;192(3):730-5. doi: 10.1016/j.juro.2014.04.017. Epub 2014 Apr 18.


The relevance of short-range fibers to cognitive efficiency and brain activation in aging and dementia.

Gao J, Cheung RT, Chan YS, Chu LW, Mak HK, Lee TM.

PLoS One. 2014 Apr 2;9(4):e90307. doi: 10.1371/journal.pone.0090307. eCollection 2014.


Xanthine derivative KMUP-1 reduces inflammation and hyperalgesia in a bilateral chronic constriction injury model by suppressing MAPK and NFκB activation.

Dai ZK, Lin TC, Liou JC, Cheng KI, Chen JY, Chu LW, Chen IJ, Wu BN.

Mol Pharm. 2014 May 5;11(5):1621-31. doi: 10.1021/mp5000086. Epub 2014 Apr 7.


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