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Discovery of Taniborbactam (VNRX-5133): A Broad-Spectrum Serine- and Metallo-β-Lactamase Inhibitor for Carbapenem-Resistant Bacterial Infections.

Liu B, Trout REL, Chu GH, McGarry D, Jackson RW, Hamrick J, Daigle D, Cusick S, Pozzi C, De Luca F, Benvenuti M, Mangani S, Docquier JD, Weiss WJ, Pevear DC, Xerri L, Burns CJ.

J Med Chem. 2019 Nov 25. doi: 10.1021/acs.jmedchem.9b01518. [Epub ahead of print]


Epoxyeicosatrienoic acid prevents maladaptive remodeling in pressure overload by targeting calcineurin/NFAT and Smad-7.

Li X, Chu G, Zhu F, Zheng Z, Wang X, Zhang G, Wang F.

Exp Cell Res. 2019 Nov 14:111716. doi: 10.1016/j.yexcr.2019.111716. [Epub ahead of print]


Yap1 Activation Enables Bypass of Oncogenic Kras Addiction in Pancreatic Cancer.

Kapoor A, Yao W, Ying H, Hua S, Liewen A, Wang Q, Zhong Y, Wu CJ, Sadanandam A, Hu B, Chang Q, Chu GC, Al-Khalil R, Jiang S, Xia H, Fletcher-Sananikone E, Lim C, Horwitz GI, Viale A, Pettazzoni P, Sanchez N, Wang H, Protopopov A, Zhang J, Heffernan T, Johnson RL, Chin L, Wang YA, Draetta G, DePinho RA.

Cell. 2019 Nov 14;179(5):1239. doi: 10.1016/j.cell.2019.10.037. No abstract available.


Leptin Receptor Mediates Bmal1 Regulation of Estrogen Synthesis in Granulosa Cells.

Chu G, Ma G, Sun J, Zhu Y, Xiang A, Yang G, Sun S.

Animals (Basel). 2019 Nov 1;9(11). pii: E899. doi: 10.3390/ani9110899.


Long noncoding RNA PCAT-1 knockdown prevents the development of ovarian cancer cells via microRNA-124-3p.

Min F, Chu G.

J Cell Biochem. 2019 Oct 31. doi: 10.1002/jcb.29431. [Epub ahead of print]


Semisynthesis of Ubiquitin and SUMO-Rhodamine 110-Glycine through Aminolysis of Boc-Protected Thioester Counterparts.

Fan J, Ye Y, Chu G, Zhang Z, Fu Y, Li YM, Shi J.

J Org Chem. 2019 Nov 15;84(22):14861-14867. doi: 10.1021/acs.joc.9b01529. Epub 2019 Nov 6.


Chain conformation and rheological properties of an acid-extracted polysaccharide from peanut sediment of aqueous extraction process.

Ye J, Hua X, Zhao Q, Zhao W, Chu G, Zhang W, Yang R.

Carbohydr Polym. 2020 Jan 15;228:115410. doi: 10.1016/j.carbpol.2019.115410. Epub 2019 Sep 30.


Efficient Semi-Synthesis of Atypical Ubiquitin Chains and Ubiquitin-Based Probes Forged by Thioether Isopeptide Bonds.

Chu GC, Hua X, Zuo C, Chen CC, Meng XB, Zhang Z, Fu Y, Shi J, Li YM.

Chemistry. 2019 Oct 17. doi: 10.1002/chem.201904010. [Epub ahead of print]


Modulating the Structural Orientation of Nanocellulose Composites through Mechano-Stimuli.

Qu D, Chu G, Martin P, Vasilyev G, Vilensky R, Zussman E.

ACS Appl Mater Interfaces. 2019 Oct 30;11(43):40443-40450. doi: 10.1021/acsami.9b12106. Epub 2019 Oct 15.


miR-125b acts as anti-fibrotic therapeutic target through regulating Gli3 in vivo and in vitro.

Hu Z, Li L, Ran J, Chu G, Gao H, Guo L, Chen J.

Ann Hepatol. 2019 Nov - Dec;18(6):825-832. doi: 10.1016/j.aohep.2019.06.016. Epub 2019 Sep 8.


Rev-erbα Inhibits Proliferation and Promotes Apoptosis of Preadipocytes through the Agonist GSK4112.

Chu G, Zhou X, Hu Y, Shi S, Yang G.

Int J Mol Sci. 2019 Sep 12;20(18). pii: E4524. doi: 10.3390/ijms20184524.


Synchronous 500-year oscillations of monsoon climate and human activity in Northeast Asia.

Xu D, Lu H, Chu G, Liu L, Shen C, Li F, Wang C, Wu N.

Nat Commun. 2019 Sep 11;10(1):4105. doi: 10.1038/s41467-019-12138-0.


Role of GABAA receptors in EEG activity and spatial recognition memory in aged APP and PS1 double transgenic mice.

Fu Y, Li L, Wang Y, Chu G, Kong X, Wang J.

Neurochem Int. 2019 Dec;131:104542. doi: 10.1016/j.neuint.2019.104542. Epub 2019 Sep 3.


Evaluation of non-invasive prenatal testing to detect chromosomal aberrations in a Chinese cohort.

Cui W, Liu X, Zhang Y, Wang Y, Chu G, He R, Zhao Y.

J Cell Mol Med. 2019 Nov;23(11):7873-7878. doi: 10.1111/jcmm.14614. Epub 2019 Aug 27.


Risk factors of sleep-disordered breathing in haemodialysis patients.

Chu G, Suthers B, Moore L, Paech GM, Hensley MJ, McDonald VM, Choi P.

PLoS One. 2019 Aug 12;14(8):e0220932. doi: 10.1371/journal.pone.0220932. eCollection 2019.


Reduction of N2O emission by biochar and/or 3,4-dimethylpyrazole phosphate (DMPP) is closely linked to soil ammonia oxidizing bacteria and nosZI-N2O reducer populations.

Chen H, Yin C, Fan X, Ye M, Peng H, Li T, Zhao Y, Wakelin SA, Chu G, Liang Y.

Sci Total Environ. 2019 Dec 1;694:133658. doi: 10.1016/j.scitotenv.2019.133658. Epub 2019 Jul 31.


Construction of Age Estimation Model of 18-Year-Olds in the Northern Chinese Population Based on the Development of Mandibular Second and Third Molars.

Chu G, Han MQ, Chen T, Zhou H, Guo YC.

Fa Yi Xue Za Zhi. 2019 Jun;35(3):289-294. doi: 10.12116/j.issn.1004-5619.2019.03.005. Epub 2019 Jun 25. English, Chinese.


Downregulation of miR-152 contributes to the progression of liver fibrosis via targeting Gli3 in vivo and in vitro.

Li L, Zhang L, Zhao X, Cao J, Li J, Chu G.

Exp Ther Med. 2019 Jul;18(1):425-434. doi: 10.3892/etm.2019.7595. Epub 2019 May 20.


A Circulating Tumor Cell-RNA Assay for Assessment of Androgen Receptor Signaling Inhibitor Sensitivity in Metastatic Castration-Resistant Prostate Cancer.

Jan YJ, Yoon J, Chen JF, Teng PC, Yao N, Cheng S, Lozano A, Chu GCY, Chung H, Lu YT, Chen PJ, Wang JJ, Lee YT, Kim M, Zhu Y, Knudsen BS, Feng FY, Garraway IP, Gao AC, Chung LWK, Freeman MR, You S, Tseng HR, Posadas EM.

Theranostics. 2019 Apr 13;9(10):2812-2826. doi: 10.7150/thno.34485. eCollection 2019.


Elaborated pollen packaging and dispensing mechanism induced by petal architecture from a Papaveraceae species.

Yang S, Chu G, Shi X, Wang S.

PeerJ. 2019 Jun 11;7:e7066. doi: 10.7717/peerj.7066. eCollection 2019.


Application of the Kvaal method for age estimation using digital panoramic radiography of Chinese individuals.

Li MJ, Chu G, Han MQ, Chen T, Zhou H, Guo YC.

Forensic Sci Int. 2019 Aug;301:76-81. doi: 10.1016/j.forsciint.2019.05.015. Epub 2019 May 15.


Role of Nkx2.5 in H2O2-induced Nsd1 suppression.

Liang X, Chu G, Wang L, Lai G, Zhao Y.

Cell Stress Chaperones. 2019 Jul;24(4):697-707. doi: 10.1007/s12192-019-00995-z. Epub 2019 May 18.


Substrate stiffness- and topography-dependent differentiation of annulus fibrosus-derived stem cells is regulated by Yes-associated protein.

Chu G, Yuan Z, Zhu C, Zhou P, Wang H, Zhang W, Cai Y, Zhu X, Yang H, Li B.

Acta Biomater. 2019 Jul 1;92:254-264. doi: 10.1016/j.actbio.2019.05.013. Epub 2019 May 9.


Hybrid Nanocomposites for 3D Optics: Using Interpolymer Complexes with Cellulose Nanocrystals.

Zhang R, Chu G, Vasilyev G, Martin P, Camposeo A, Persano L, Pisignano D, Zussman E.

ACS Appl Mater Interfaces. 2019 May 29;11(21):19324-19330. doi: 10.1021/acsami.9b01699. Epub 2019 May 14.


Hhip inhibits proliferation and promotes differentiation of adipocytes through suppressing hedgehog signaling pathway.

Wei H, Li J, Shi S, Zhang L, Xiang A, Shi X, Yang G, Chu G.

Biochem Biophys Res Commun. 2019 Jun 18;514(1):148-156. doi: 10.1016/j.bbrc.2019.04.047. Epub 2019 Apr 24.


Establishment and characterization of a prostate cancer cell line from a prostatectomy specimen for the study of cellular interaction.

Wang R, Chu GC, Wang X, Wu JB, Hu P, Multani AS, Pathak S, Zhau HE, Chung LWK.

Int J Cancer. 2019 Oct 15;145(8):2249-2259. doi: 10.1002/ijc.32370. Epub 2019 May 10.


Selection of suitable reference genes for core clock gene expression analysis by real-time qPCR in rat ovary granulosa cells.

Cai C, Cai P, Chu G.

Mol Biol Rep. 2019 Jun;46(3):2941-2946. doi: 10.1007/s11033-019-04755-1. Epub 2019 Apr 23.


Hyperammonemia after capecitabine associated with occult impairment of the urea cycle.

Chu G, Salzman J.

Cancer Med. 2019 May;8(5):1996-2004. doi: 10.1002/cam4.2036. Epub 2019 Apr 11.


Two Pairs of Isomerically New Phenylpropanoidated Epicatechin Gallates with Neuroprotective Effects on H2O2-Injured SH-SY5Y Cells from Zijuan Green Tea and Their Changes in Fresh Tea Leaves Collected from Different Months and Final Product.

Ke JP, Dai WT, Zheng WJ, Wu HY, Hua F, Hu FL, Chu GX, Bao GH.

J Agric Food Chem. 2019 May 1;67(17):4831-4838. doi: 10.1021/acs.jafc.9b01365. Epub 2019 Apr 17.


The applied anatomy and clinical significance of the proximal, V1 segment of vertebral artery.

Li X, Guan L, Zilundu PLM, Chen J, Chen Z, Ma M, Zhuang H, Zhuang Z, Qiu Y, Ye F, Wu X, Sang H, Ye Y, Han Y, Yao H, Li H, Zhong G, Wu H, Jiang Z, Chu G, Xu D, Zhou L.

Folia Morphol (Warsz). 2019 Apr 5. doi: 10.5603/FM.a2019.0039. [Epub ahead of print]


Exclusion and Trapping of Carbon Nanostructures in Nonisotropic Suspensions of Cellulose Nanostructures.

Mendelson O, Chu G, Ziv E, Levi-Kalisman Y, Vasilyev G, Zussman E, Yerushalmi-Rozen R.

J Phys Chem B. 2019 Apr 25;123(16):3535-3542. doi: 10.1021/acs.jpcb.9b02227. Epub 2019 Apr 15.


Atrial fibrillation and cancer - An unexplored field in cardiovascular oncology.

Chu G, Versteeg HH, Verschoor AJ, Trines SA, Hemels MEW, Ay C, Huisman MV, Klok FA.

Blood Rev. 2019 May;35:59-67. doi: 10.1016/j.blre.2019.03.005. Epub 2019 Mar 25. Review.


The role of electron shuttle enhances Fe(III)-mediated reduction of Cr(VI) by Shewanella oneidensis MR-1.

Liu X, Chu G, Du Y, Li J, Si Y.

World J Microbiol Biotechnol. 2019 Mar 28;35(4):64. doi: 10.1007/s11274-019-2634-9.


The relative importance of different carbon structures in biochars to carbamazepine and bisphenol A sorption.

Chu G, Zhao J, Liu Y, Lang D, Wu M, Pan B, Steinberg CEW.

J Hazard Mater. 2019 Jul 5;373:106-114. doi: 10.1016/j.jhazmat.2019.03.078. Epub 2019 Mar 19.


Cu2+-assisted laccase from Trametes versicolor enhanced self-polyreaction of triclosan.

Sun K, Li S, Yu J, Gong R, Si Y, Liu X, Chu G.

Chemosphere. 2019 Jun;225:745-754. doi: 10.1016/j.chemosphere.2019.03.079. Epub 2019 Mar 15.


Evaluation of ε-polylysine as antimicrobial alternative for liquid-stored boar semen.

Shaoyong W, Li Q, Ren ZQ, Wei CS, Chu GY, Dong WZ, Yang GS, Pang WJ.

Theriogenology. 2019 May;130:146-156. doi: 10.1016/j.theriogenology.2019.03.005. Epub 2019 Mar 12.


Targeting Burkitt lymphoma with a tumor cell-specific heptamethine carbocyanine-cisplatin conjugate.

Mrdenovic S, Zhang Y, Wang R, Yin L, Chu GC, Yin L, Lewis M, Heffer M, Zhau HE, Chung LWK.

Cancer. 2019 Mar 6. doi: 10.1002/cncr.32033. [Epub ahead of print]


Efficacy of systemic temozolomide-activated phage-targeted gene therapy in human glioblastoma.

Przystal JM, Waramit S, Pranjol MZI, Yan W, Chu G, Chongchai A, Samarth G, Olaciregui NG, Tabatabai G, Carcaboso AM, Aboagye EO, Suwan K, Hajitou A.

EMBO Mol Med. 2019 Apr;11(4). pii: e8492. doi: 10.15252/emmm.201708492.


Age assessment in the living using modified Gustafson's criteria in a northern Chinese population.

Si XQ, Chu G, Olze A, Schmidt S, Schulz R, Chen T, Pfeiffer H, Guo YC, Schmeling A.

Int J Legal Med. 2019 May;133(3):921-930. doi: 10.1007/s00414-019-02024-1. Epub 2019 Feb 21.


Regulatory signaling network in the tumor microenvironment of prostate cancer bone and visceral organ metastases and the development of novel therapeutics.

Chu GC, Chung LWK, Gururajan M, Hsieh CL, Josson S, Nandana S, Sung SY, Wang R, Wu JB, Zhau HE.

Asian J Urol. 2019 Jan;6(1):65-81. doi: 10.1016/j.ajur.2018.11.003. Epub 2018 Nov 28. Review.


Cysteine-Aminoethylation-Assisted Chemical Ubiquitination of Recombinant Histones.

Chu GC, Pan M, Li J, Liu S, Zuo C, Tong ZB, Bai JS, Gong Q, Ai H, Fan J, Meng X, Huang YC, Shi J, Deng H, Tian C, Li YM, Liu L.

J Am Chem Soc. 2019 Feb 27;141(8):3654-3663. doi: 10.1021/jacs.8b13213. Epub 2019 Feb 13.


ElectroMap: High-throughput open-source software for analysis and mapping of cardiac electrophysiology.

O'Shea C, Holmes AP, Yu TY, Winter J, Wells SP, Correia J, Boukens BJ, De Groot JR, Chu GS, Li X, Ng GA, Kirchhof P, Fabritz L, Rajpoot K, Pavlovic D.

Sci Rep. 2019 Feb 4;9(1):1389. doi: 10.1038/s41598-018-38263-2.


The short-term effects of outdoor temperature on blood pressure among children and adolescents: finding from a large sample cross-sectional study in Suzhou, China.

Hu J, Shen H, Teng CG, Han D, Chu GP, Zhou YK, Wang Q, Wang B, Wu JZ, Xiao Q, Liu F, Yang HB.

Int J Biometeorol. 2019 Mar;63(3):381-391. doi: 10.1007/s00484-019-01671-8. Epub 2019 Jan 29.


IGFBP5 suppresses oleate-induced intramyocellular lipids deposition and enhances insulin signaling.

Xiang A, Chu G, Zhu Y, Ma G, Yang G, Sun S.

J Cell Physiol. 2019 Jan 26. doi: 10.1002/jcp.28174. [Epub ahead of print]


What influences tourists' intention to participate in the Zero Litter Initiative in mountainous tourism areas: A case study of Huangshan National Park, China.

Hu H, Zhang J, Wang C, Yu P, Chu G.

Sci Total Environ. 2019 Mar 20;657:1127-1137. doi: 10.1016/j.scitotenv.2018.12.114. Epub 2018 Dec 10.


Localization and expression of CTRP6 in ovary and its regulation by FSH in porcine granulosa cells.

Yin L, Wang W, Wei H, Xi F, Chu G, Yang G.

Theriogenology. 2019 Mar 15;127:56-65. doi: 10.1016/j.theriogenology.2019.01.009. Epub 2019 Jan 12.


A convenient method to verify the accuracy of oscillometric blood pressure monitors by the auscultatory method: A smartphone-based app.

Zhang Z, Xi W, Wang B, Chu G, Wang F.

J Clin Hypertens (Greenwich). 2019 Feb;21(2):173-180. doi: 10.1111/jch.13460. Epub 2018 Dec 20.


Accuracy and safety of percutaneous periacetabular screw insertion using screw view model of navigation in acetabular fracture: A case report.

Zhao JW, Yu T, Chu GY, Zhang XW, Wang Y, Zhu XJ, Jiang QY, Jiang ZD, Wang DS.

Medicine (Baltimore). 2018 Dec;97(49):e13316. doi: 10.1097/MD.0000000000013316.


Systematic differences of non-invasive dominant frequency estimation compared to invasive dominant frequency estimation in atrial fibrillation.

Vanheusden FJ, Chu GS, Li X, Salinet J, Almeida TP, Dastagir N, Stafford PJ, Ng GA, Schlindwein FS.

Comput Biol Med. 2019 Jan;104:299-309. doi: 10.1016/j.compbiomed.2018.11.017. Epub 2018 Nov 25.

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