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Necuparanib, a multi-targeting heparan sulfate mimetic, targets tumor and stromal compartments in pancreatic cancer.

MacDonald A, Priess M, Curran J, Guess J, Farutin V, Oosterom I, Chu CL, Cochran E, Zhang L, Getchell K, Lolkema M, Schultes BC, Krause S.

Mol Cancer Ther. 2018 Nov 6. pii: molcanther.0417.2018. doi: 10.1158/1535-7163.MCT-18-0417. [Epub ahead of print]


Src-family kinase-Cbl axis negatively regulates NLRP3 inflammasome activation.

Chung IC, Yuan SN, OuYang CN, Lin HC, Huang KY, Chen YJ, Chung AK, Chu CL, Ojcius DM, Chang YS, Chen LC.

Cell Death Dis. 2018 Oct 31;9(11):1109. doi: 10.1038/s41419-018-1163-z.


Association Between Polymorphisms in Dopamine-Related Genes and Orthopedic Pain Expression in a Chinese Elderly Population.

Chu CS, Chu CL, Liang CK, Lu T, Lin YT, Chou MY, Chow PC.

Pain Pract. 2018 Oct 14. doi: 10.1111/papr.12737. [Epub ahead of print]


The association between exposure to second-hand smoke and major depressive disorder in perimenopausal women: results from apopulation-based study.

Chen CY, Chang CM, Lin HL, Chu CL.

Ann Med. 2018 Nov 19:1-9. doi: 10.1080/07853890.2018.1534264. [Epub ahead of print]


Effects of Etching Variations on Ge/Si Channel Formation and Device Performance.

Chen JL, Fuh YK, Chu CL.

Nanoscale Res Lett. 2018 Jul 31;13(1):226. doi: 10.1186/s11671-018-2631-1.


Decreased IL-1ra and NCAM-1/CD56 Serum Levels in Unmedicated Patients with Schizophrenia Before and After Antipsychotic Treatment.

Chu CS, Li DJ, Chu CL, Wu CC, Lu T.

Psychiatry Investig. 2018 Jul;15(7):727-732. doi: 10.30773/pi.2017.11.10. Epub 2018 Jun 15.


An observational study: The utility of perfusion index as a discharge criterion for pain assessment in the postanesthesia care unit.

Chu CL, Huang YY, Chen YH, Lai LP, Yeh HM.

PLoS One. 2018 May 16;13(5):e0197630. doi: 10.1371/journal.pone.0197630. eCollection 2018.


Gold lotion from citrus peel extract ameliorates imiquimod-induced psoriasis-like dermatitis in murine.

Lin CC, Wu JJ, Pan YG, Chao YH, Lin FC, Lee YR, Chu CL.

J Sci Food Agric. 2018 Nov;98(14):5509-5517. doi: 10.1002/jsfa.9097. Epub 2018 Jun 13.


The sociocultural effects on orthopedic surgeries in Taiwan.

Chiu SL, Gee MJ, Muo CH, Chu CL, Lan SJ, Chen CL.

PLoS One. 2018 Mar 29;13(3):e0195183. doi: 10.1371/journal.pone.0195183. eCollection 2018.


Serum nerve growth factor beta, brain- and glial-derived neurotrophic factor levels and psychopathology in unmedicated patients with schizophrenia.

Chu CS, Chu CL, Wu CC, Lu T.

J Chin Med Assoc. 2018 Jun;81(6):577-581. doi: 10.1016/j.jcma.2017.11.010. Epub 2018 Feb 1.


FcεRI γ-Chain Negatively Modulates Dectin-1 Responses in Dendritic Cells.

Pan YG, Yu YL, Lin CC, Lanier LL, Chu CL.

Front Immunol. 2017 Oct 27;8:1424. doi: 10.3389/fimmu.2017.01424. eCollection 2017.


Biomarkers and echocardiography for evaluating the improvement of the ventricular diastolic function after surgical relief of hydronephrosis.

Yeh HM, Lin TT, Yeh CF, Huang HS, Chang SN, Lin JW, Tsai CT, Lai LP, Huang YY, Chu CL.

PLoS One. 2017 Nov 21;12(11):e0188597. doi: 10.1371/journal.pone.0188597. eCollection 2017.


Leading Comorbidity associated with 30-day post-anesthetic mortality in geriatric surgical patients in Taiwan: a retrospective study from the health insurance data.

Chu CL, Chiou HY, Chou WH, Chang PY, Huang YY, Yeh HM.

BMC Geriatr. 2017 Oct 24;17(1):245. doi: 10.1186/s12877-017-0629-7.


Availability of dopamine transporters and auditory P300 abnormalities in adults with attention-deficit hyperactivity disorder: preliminary results.

Chu CL, Lee IH, Chi MH, Chen KC, Chen PS, Yao WJ, Chiu NT, Yang YK.

CNS Spectr. 2018 Aug;23(4):264-270. doi: 10.1017/S1092852917000049. Epub 2017 Aug 29.


SHP-1 (PTPN6) keeps the inflammation at bay: limiting IL-1α-mediated neutrophilic dermatoses by preventing Syk kinase activation.

You RI, Chu CL.

Cell Mol Immunol. 2017 Jul 10. doi: 10.1038/cmi.2017.59. [Epub ahead of print] No abstract available.


Service system and cognitive outcomes for young children with autism spectrum disorders in a rural area of Taiwan.

Chu CL, Chiang CH, Wu CC, Hou YM, Liu JH.

Autism. 2017 Jul;21(5):581-591. doi: 10.1177/1362361316664867. Epub 2016 Oct 20.


Mini-Nutritional Assessment Short-Form as a useful method of predicting poor 1-year outcome in elderly patients undergoing orthopedic surgery.

Chu CS, Liang CK, Chou MY, Lu T, Lin YT, Chu CL.

Geriatr Gerontol Int. 2017 Dec;17(12):2361-2368. doi: 10.1111/ggi.13075. Epub 2017 Jun 5.


Demographics and Clinical Features of Postresuscitation Comorbidities in Long-Term Survivors of Out-of-Hospital Cardiac Arrest: A National Follow-Up Study.

Su CP, Wu JH, Yang MC, Liao CH, Hsu HY, Chang CF, Lan SJ, Chu CL, Lin YR.

Biomed Res Int. 2017;2017:9259182. doi: 10.1155/2017/9259182. Epub 2017 Feb 13.


Identification and Validation of Gene Expression Patterns in Cystitis Glandularis Patients and Controls.

Chu CL, Zhao CH, Zhang ZW, Wang MW, Zhang ZH, Yang AQ, Ma BB, Lu CF, Wu M, Gu MZ, Cui RJ, Xin ZX, Huang T, Zhou WL.

SLAS Discov. 2017 Jul;22(6):743-750. doi: 10.1177/2472555216685519. Epub 2017 Jan 6.


IL-36 Signaling Facilitates Activation of the NLRP3 Inflammasome and IL-23/IL-17 Axis in Renal Inflammation and Fibrosis.

Chi HH, Hua KF, Lin YC, Chu CL, Hsieh CY, Hsu YJ, Ka SM, Tsai YL, Liu FC, Chen A.

J Am Soc Nephrol. 2017 Jul;28(7):2022-2037. doi: 10.1681/ASN.2016080840. Epub 2017 Feb 8.


Spleen tyrosine kinase mediates the actions of EPO and GM-CSF and coordinates with TGF-β in erythropoiesis.

Chang HC, Huang DY, Wu MS, Chu CL, Tzeng SJ, Lin WW.

Biochim Biophys Acta Mol Cell Res. 2017 Apr;1864(4):687-696. doi: 10.1016/j.bbamcr.2017.01.014. Epub 2017 Jan 25.


NLRP3 inflammasome: Pathogenic role and potential therapeutic target for IgA nephropathy.

Tsai YL, Hua KF, Chen A, Wei CW, Chen WS, Wu CY, Chu CL, Yu YL, Lo CW, Ka SM.

Sci Rep. 2017 Jan 24;7:41123. doi: 10.1038/srep41123.


Serum DHEA-S concentration correlates with clinical symptoms and neurocognitive function in patients with bipolar II disorder: A case-controlled study.

Lee SY, Wang LJ, Chang CH, Wu CC, Chen HL, Lin SH, Chu CL, Lu T, Lu RB.

Prog Neuropsychopharmacol Biol Psychiatry. 2017 Mar 6;74:31-35. doi: 10.1016/j.pnpbp.2016.11.006. Epub 2016 Nov 30.


A reliability generalization meta-analysis of coefficient alpha and test-retest coefficient for the aging males' symptoms (AMS) scale.

Lee CP, Chiu YW, Chu CL, Chen Y, Jiang KH, Chen JL, Chen CY.

Aging Male. 2016 Dec;19(4):244-253. Epub 2016 Nov 22.


Pyk2 activates the NLRP3 inflammasome by directly phosphorylating ASC and contributes to inflammasome-dependent peritonitis.

Chung IC, OuYang CN, Yuan SN, Li HP, Chen JT, Shieh HR, Chen YJ, Ojcius DM, Chu CL, Yu JS, Chang YS, Chen LC.

Sci Rep. 2016 Oct 31;6:36214. doi: 10.1038/srep36214.


Availability of Striatal Dopamine Transporter in Healthy Individuals With and Without a Family History of ADHD.

Tai YC, Chi MH, Chu CL, Chiu NT, Yao WJ, Chen PS, Yang YK.

J Atten Disord. 2016 Jul 7. pii: 1087054716654570. [Epub ahead of print]


Lack of Association between Pre-Operative Insulin-Like Growth Factor-1 and the Risk of Post-Operative Delirium in Elderly Chinese Patients.

Chu CS, Liang CK, Chou MY, Lin YT, Hsu CJ, Chu CL, Chou PH.

Psychiatry Investig. 2016 May;13(3):327-32. doi: 10.4306/pi.2016.13.3.327. Epub 2016 May 18.


Fabrication and apatite inducing ability of different porous titania structures by PEO treatment.

Rao X, Chu CL, Sun Q, Zheng YY.

Mater Sci Eng C Mater Biol Appl. 2016 Sep 1;66:297-305. doi: 10.1016/j.msec.2016.04.038. Epub 2016 Apr 13.


Development of a short version of the Aging Males' Symptoms scale: Mokken scaling analysis and Rasch analysis.

Lee CP, Chen Y, Jiang KH, Chu CL, Chiu YW, Chen JL, Chen CY.

Aging Male. 2016 Jun;19(2):117-23. doi: 10.3109/13685538.2016.1157861. Epub 2016 Mar 17.


Use of antipsychotics and risk of venous thromboembolism in postmenopausal women. A population-based nested case-control study.

Wang MT, Liou JT, Huang YW, Lin CW, Wu GJ, Chu CL, Yeh CB, Wang YH.

Thromb Haemost. 2016 Jun 2;115(6):1209-19. doi: 10.1160/TH15-11-0895. Epub 2016 Mar 3.


The Prevalence and the Incidence of Diagnosed Open-Angle Glaucoma and Diagnosed Angle-Closure Glaucoma: Changes From 2001 to 2010.

Chiu SL, Chu CL, Muo CH, Chen CL, Lan SJ.

J Glaucoma. 2016 May;25(5):e514-9. doi: 10.1097/IJG.0000000000000381.


Erratum to: Recombinant viral protein VP1 suppresses HER-2 expression and migration/metastasis of breast cancer.

Hung SW, Chiu CF, Chen TA, Chu CL, Huang CC, Shyur LF, Liang CM, Liang SM.

Breast Cancer Res Treat. 2016 Feb;155(3):609-12. doi: 10.1007/s10549-016-3711-5. No abstract available.


Ultra-large suspended graphene as a highly elastic membrane for capacitive pressure sensors.

Chen YM, He SM, Huang CH, Huang CC, Shih WP, Chu CL, Kong J, Li J, Su CY.

Nanoscale. 2016 Feb 14;8(6):3555-64. doi: 10.1039/c5nr08668j. Epub 2016 Jan 25.


Short-Form Mini Nutritional Assessment as a useful method of predicting the development of postoperative delirium in elderly patients undergoing orthopedic surgery.

Chu CS, Liang CK, Chou MY, Lin YT, Hsu CJ, Chou PH, Chu CL.

Gen Hosp Psychiatry. 2016 Jan-Feb;38:15-20. doi: 10.1016/j.genhosppsych.2015.08.006. Epub 2015 Sep 1.


Naringenin inhibits dendritic cell maturation and has therapeutic effects in a murine model of collagen-induced arthritis.

Li YR, Chen DY, Chu CL, Li S, Chen YK, Wu CL, Lin CC.

J Nutr Biochem. 2015 Dec;26(12):1467-78. doi: 10.1016/j.jnutbio.2015.07.016. Epub 2015 Aug 8.


Antidepressant use and risk of recurrent stroke: a population-based nested case-control study.

Wang MT, Chu CL, Yeh CB, Chang LC, Malone DC, Liou JT.

J Clin Psychiatry. 2015 Jul;76(7):e877-85. doi: 10.4088/JCP.14m09134.


The Chinese Version of the Gotland Male Depression Scale (GMDS): Mokken scaling.

Lee CP, Chu CL, Chen Y, Jiang KH, Chen JL, Chen CY.

J Affect Disord. 2015 Nov 1;186:48-52. doi: 10.1016/j.jad.2015.06.045. Epub 2015 Jul 21.


Trends in Glaucoma Medication Expenditures under Universal Health Coverage: A National Population-Based Longitudinal Survey in Taiwan.

Chiu SL, Chu CL, Muo CH, Chen CL, Lan SJ.

J Ophthalmol. 2015;2015:243401. doi: 10.1155/2015/243401. Epub 2015 Jun 2.


CR3 and Dectin-1 Collaborate in Macrophage Cytokine Response through Association on Lipid Rafts and Activation of Syk-JNK-AP-1 Pathway.

Huang JH, Lin CY, Wu SY, Chen WY, Chu CL, Brown GD, Chuu CP, Wu-Hsieh BA.

PLoS Pathog. 2015 Jul 1;11(7):e1004985. doi: 10.1371/journal.ppat.1004985. eCollection 2015 Jul.


Paxillin confers resistance to tyrosine kinase inhibitors in EGFR-mutant lung cancers via modulating BIM and Mcl-1 protein stability.

Wu DW, Chen CY, Chu CL, Lee H.

Oncogene. 2016 Feb 4;35(5):621-30. doi: 10.1038/onc.2015.120. Epub 2015 Apr 27.


Efficacy of caregiver-mediated joint engagement intervention for young children with autism spectrum disorders.

Chiang CH, Chu CL, Lee TC.

Autism. 2016 Feb;20(2):172-82. doi: 10.1177/1362361315575725. Epub 2015 Apr 20.


Tragic result of traditional Chinese medicine manipulation: an unusual case report of bilateral anterior shoulder dislocations.

Chen CL, Chiu SL, Chu CL, Lan SJ.

BMC Complement Altern Med. 2015 Mar 31;15:98. doi: 10.1186/s12906-015-0633-4.


Developing a Prediction Model for Post-Operative Delirium and Long-Term Outcomes Among Older Patients Receiving Elective Orthopedic Surgery: A Prospective Cohort Study in Taiwan.

Liang CK, Chu CL, Chou MY, Lin YT, Lu T, Hsu CJ, Lam HC, Chen LK.

Rejuvenation Res. 2015 Aug;18(4):347-55. doi: 10.1089/rej.2014.1645.


Biodegradable poly-lactic acid based-composite reinforced unidirectionally with high-strength magnesium alloy wires.

Li X, Chu CL, Liu L, Liu XK, Bai J, Guo C, Xue F, Lin PH, Chu PK.

Biomaterials. 2015 May;49:135-44. doi: 10.1016/j.biomaterials.2015.01.060. Epub 2015 Feb 16.


The adjuvant effects of high-molecule-weight polysaccharides purified from Antrodia cinnamomea on dendritic cell function and DNA vaccines.

Lin CC, Pan IH, Li YR, Pan YG, Lin MK, Lu YH, Wu HC, Chu CL.

PLoS One. 2015 Feb 27;10(2):e0116191. doi: 10.1371/journal.pone.0116191. eCollection 2015.


The prevalence and correlates of the positive Androgen Deficiency in the Aging Male (ADAM) questionnaire among psychiatric outpatients: a cross-sectional survey of 176 men in a general hospital in Taiwan.

Lee CP, Chen Y, Jiang KH, Chu CL, Hsu SC, Chen JL, Chen CY.

Neuropsychiatr Dis Treat. 2015 Jan 20;11:185-9. doi: 10.2147/NDT.S75701. eCollection 2015.


Perfusion index derived from a pulse oximeter can detect changes in peripheral microcirculation during uretero-renal-scopy stone manipulation (URS-SM).

Huang HS, Chu CL, Tsai CT, Wu CK, Lai LP, Yeh HM.

PLoS One. 2014 Dec 26;9(12):e115743. doi: 10.1371/journal.pone.0115743. eCollection 2014.


The correlation between mid-brain serotonin transporter availability and intelligence quotient in healthy volunteers.

Tseng PY, Lee IH, Chen KC, Chen PS, Chiu NT, Yao WJ, Chu CL, Yeh TL, Yang YK.

Eur Psychiatry. 2015 Feb;30(2):193-7. doi: 10.1016/j.eurpsy.2014.09.001. Epub 2014 Oct 28.


Interrelationship of postoperative delirium and cognitive impairment and their impact on the functional status in older patients undergoing orthopaedic surgery: a prospective cohort study.

Liang CK, Chu CL, Chou MY, Lin YT, Lu T, Hsu CJ, Chen LK.

PLoS One. 2014 Nov 17;9(11):e110339. doi: 10.1371/journal.pone.0110339. eCollection 2014.


Antithyroid drug-related hepatotoxicity in hyperthyroidism patients: a population-based cohort study.

Wang MT, Lee WJ, Huang TY, Chu CL, Hsieh CH.

Br J Clin Pharmacol. 2014 Sep;78(3):619-29.

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