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Items: 41

1.

Influenza-associated mortality in hospital care: a retrospective cohort study of risk factors and impact of oseltamivir in an English teaching hospital, 2016 to 2017.

Reacher M, Warne B, Reeve L, Verlander NQ, Jones NK, Ranellou K, Christou S, Wright C, Choudhry S, Zambon M, Sander C, Zhang H, Jalal H.

Euro Surveill. 2019 Oct;24(44). doi: 10.2807/1560-7917.ES.2019.24.44.1900087.

2.

Marital status and paternity in patients with Transfusion- Dependent Thalassemia (TDT) and Non Transfusion-Dependent Thalassemia (NTDT): an ICET - A survey in different countries.

De Sanctis V, Soliman AT, El-Hakim I, Christou S, Mariannis D, Karimi M, Ladis V, Kattamis A, Daar S, Yassin M, Canatan D, Galati MC, Raiola G, Campisi S, Kakkar S, Kaleva V, Saki F, Ellinides A, Pikis G, Christodoulides C, Abdulla M, Di Maio S, Theodoridis C, Elsedfy H, Kattamis C.

Acta Biomed. 2019 Sep 6;90(3):225-237. doi: 10.23750/abm.v90i3.8586.

PMID:
31580308
3.

A novel mutation in the erythroid transcription factor KLF1 is likely responsible for ameliorating β-thalassemia major.

Fanis P, Kousiappa I, Phylactides M, Kyrri A, Hadjigavriel M, Christou S, Sitarou M, Kleanthous M.

Hum Mutat. 2019 Oct;40(10):1768-1780. doi: 10.1002/humu.23817. Epub 2019 Jun 24.

4.

Correction of IVS I-110(G>A) β-thalassemia by CRISPR/Cas-and TALEN-mediated disruption of aberrant regulatory elements in human hematopoietic stem and progenitor cells.

Patsali P, Turchiano G, Papasavva P, Romito M, Loucari CC, Stephanou C, Christou S, Sitarou M, Mussolino C, Cornu TI, Antoniou MN, Lederer CW, Cathomen T, Kleanthous M.

Haematologica. 2019 Nov;104(11):e497-e501. doi: 10.3324/haematol.2018.215178. Epub 2019 Apr 19. No abstract available.

5.

Circadian regulation in human white adipose tissue revealed by transcriptome and metabolic network analysis.

Christou S, Wehrens SMT, Isherwood C, Möller-Levet CS, Wu H, Revell VL, Bucca G, Skene DJ, Laing EE, Archer SN, Johnston JD.

Sci Rep. 2019 Feb 25;9(1):2641. doi: 10.1038/s41598-019-39668-3.

6.

An ICET-A survey on occult and emerging endocrine complications in patients with β-thalassemia major: Conclusions and recommendations.

De Sanctis V, Soliman AT, Canatan D, Tzoulis P, Daar S, Di Maio S, Elsedfy H, Yassin MA, Filosa A, Soliman N, Mehran K, Saki F, Sobti P, Kakkar S, Christou S, Albu A, Christodoulides C, Kilinc Y, Al Jaouni S, Khater D, Alyaarubi SA, Lum SH, Campisi S, Anastasi S, Galati MC, Raiola G, Wali Y, Elhakim IZ, Mariannis D, Ladis V, Kattamis C.

Acta Biomed. 2019 Jan 15;89(4):481-489. doi: 10.23750/abm.v89i4.7774.

7.

Managing Delayed Suprachoroidal Hemorrhage After Insertion of XEN45 Glaucoma Device.

Stringa F, Ali Z, Christou S, Karandikar S, Shankar V.

J Glaucoma. 2019 May;28(5):e72-e74. doi: 10.1097/IJG.0000000000001170.

PMID:
30585940
8.

Application of long single-stranded DNA donors in genome editing: generation and validation of mouse mutants.

Codner GF, Mianné J, Caulder A, Loeffler J, Fell R, King R, Allan AJ, Mackenzie M, Pike FJ, McCabe CV, Christou S, Joynson S, Hutchison M, Stewart ME, Kumar S, Simon MM, Agius L, Anstee QM, Volynski KE, Kullmann DM, Wells S, Teboul L.

BMC Biol. 2018 Jun 21;16(1):70. doi: 10.1186/s12915-018-0530-7.

9.

Short-hairpin RNA against aberrant HBBIVSI-110(G>A) mRNA restores β-globin levels in a novel cell model and acts as mono- and combination therapy for β-thalassemia in primary hematopoietic stem cells.

Patsali P, Papasavva P, Stephanou C, Christou S, Sitarou M, Antoniou MN, Lederer CW, Kleanthous M.

Haematologica. 2018 Sep;103(9):e419-e423. doi: 10.3324/haematol.2018.189357. Epub 2018 Apr 26. No abstract available.

10.

An ICET- A survey on Hypoparathyroidism in Patients with Thalassaemia Major and Intermedia: A preliminary report.

De Sanctis V, Soliman AT, Canatan D, Elsedfy H, Karimi M, Daar S, Rimawi H, Christou S, Skordis N, Tzoulis P, Sobti P, Kakkar S, Kilinc Y, Khater D, Alyaarubi SA, Kaleva V, Lum SH, Yassin MA, Saki F, Obiedat M, Anastasi S, Galati MC, Raiola G, Campisi S, Soliman N, Elshinawy M, Jaouni SA, Di Maio S, Wali Y, Elhakim IZ, Kattamis C.

Acta Biomed. 2018 Jan 16;88(4):435-444. doi: 10.23750/abm.v88i4.6837.

11.

Rapid and Sensitive Assessment of Globin Chains for Gene and Cell Therapy of Hemoglobinopathies.

Loucari CC, Patsali P, van Dijk TB, Stephanou C, Papasavva P, Zanti M, Kurita R, Nakamura Y, Christou S, Sitarou M, Philipsen S, Lederer CW, Kleanthous M.

Hum Gene Ther Methods. 2018 Feb;29(1):60-74. doi: 10.1089/hgtb.2017.190.

12.

First study on iron complexes in blood and organ samples from thalassaemic and normal laboratory mice using Mössbauer spectroscopy.

Charitou G, Petousis V, Tsertos C, Parpottas Y, Kleanthous M, Phylactides M, Christou S.

Eur Biophys J. 2018 Mar;47(2):131-138. doi: 10.1007/s00249-017-1234-6. Epub 2017 Jul 10.

PMID:
28695249
13.

Meal Timing Regulates the Human Circadian System.

Wehrens SMT, Christou S, Isherwood C, Middleton B, Gibbs MA, Archer SN, Skene DJ, Johnston JD.

Curr Biol. 2017 Jun 19;27(12):1768-1775.e3. doi: 10.1016/j.cub.2017.04.059. Epub 2017 Jun 1.

14.

Review and Recommendations on Management of Adult Female Thalassemia Patients with Hypogonadism based on Literature Review and Experience of ICET-A Network Specialists.

De Sanctis V, Soliman AT, Elsedfy H, Albu A, Al Jaouni S, Anastasi S, Bisconte MG, Canatan D, Christou S, Daar S, Di Maio S, El Kholy M, Khater D, Elshinawy M, Kilinc Y, Mattei R, Mosli HH, Quota A, Roberti MG, Sobti P, Yaarubi SA, Canpisi S, Kattamis C.

Mediterr J Hematol Infect Dis. 2017 Jan 1;9(1):e2017001. doi: 10.4084/MJHID.2017.001. eCollection 2017. Review.

15.

Suitability of small diagnostic peripheral-blood samples for cell-therapy studies.

Stephanou C, Papasavva P, Zachariou M, Patsali P, Epitropou M, Ladas P, Al-Abdulla R, Christou S, Antoniou MN, Lederer CW, Kleanthous M.

Cytotherapy. 2017 Feb;19(2):311-326. doi: 10.1016/j.jcyt.2016.11.007.

PMID:
28088294
16.

Hb A2 Episkopi - a novel δ-globin chain variant [HBD:c.428C>T] in a family of mixed Cypriot-Lebanese descent.

Lederer CW, Pavlou E, Tanteles GA, Evangelidou P, Sismani C, Kolnagou A, Sitarou M, Christou S, Hadjigavriel M, Kleanthous M.

Hematology. 2017 Jun;22(5):304-309. doi: 10.1080/10245332.2016.1265043. Epub 2016 Dec 22.

PMID:
28007020
17.

Health and rescue services management system during a crisis event.

Kyriacou E, Nicolaidou I, Hadjichristofi G, Kyprianou S, Christou S, Constantinou R.

Healthc Technol Lett. 2016 Sep 27;3(3):205-211. eCollection 2016 Sep.

18.

The molecular spectrum and distribution of haemoglobinopathies in Cyprus: a 20-year retrospective study.

Kountouris P, Kousiappa I, Papasavva T, Christopoulos G, Pavlou E, Petrou M, Feleki X, Karitzie E, Phylactides M, Fanis P, Lederer CW, Kyrri AR, Kalogerou E, Makariou C, Ioannou C, Kythreotis L, Hadjilambi G, Andreou N, Pangalou E, Savvidou I, Angastiniotis M, Hadjigavriel M, Sitarou M, Kolnagou A, Kleanthous M, Christou S.

Sci Rep. 2016 May 20;6:26371. doi: 10.1038/srep26371.

19.

Free-Floating Iris Pigmented Epithelial Cyst in the Anterior Chamber.

Rotsos T, Bagikos G, Christou S, Symeonidis C, Papadaki T, Papaeuthimiou I, Miltsakakis D.

Case Rep Ophthalmol Med. 2016;2016:4731037. doi: 10.1155/2016/4731037. Epub 2016 Jan 21.

20.

Infections in patients undergoing craniotomy: risk factors associated with post-craniotomy meningitis.

Kourbeti IS, Vakis AF, Ziakas P, Karabetsos D, Potolidis E, Christou S, Samonis G.

J Neurosurg. 2015 May;122(5):1113-9. doi: 10.3171/2014.8.JNS132557. Epub 2014 Oct 24.

PMID:
25343179
21.

Hb Famagusta--analysis of a novel δ-globin chain variant [HBD:c.60C>A] in four families with diverse globin genotypes.

Lederer CW, Pavlou E, Makariou C, Hadjilambi G, Andreou N, Hadjigavriel M, Kolnagou A, Sitarou M, Christou S, Kleanthous M.

Ann Hematol. 2014 Sep;93(9):1625-7. doi: 10.1007/s00277-013-1996-6. Epub 2014 Jan 23. No abstract available.

PMID:
24452365
22.

A synthetic approach to novel carvotacetone and antheminone analogues with anti-tumour activity.

Christou S, Ozturk E, Pritchard RG, Quayle P, Stratford IJ, Whitehead RC, Williams KF.

Bioorg Med Chem Lett. 2013 Sep 15;23(18):5066-9. doi: 10.1016/j.bmcl.2013.07.041. Epub 2013 Jul 26.

PMID:
23937978
23.

KLF10 gene expression is associated with high fetal hemoglobin levels and with response to hydroxyurea treatment in β-hemoglobinopathy patients.

Borg J, Phylactides M, Bartsakoulia M, Tafrali C, Lederer C, Felice AE, Papachatzopoulou A, Kourakli A, Stavrou EF, Christou S, Hou J, Karkabouna S, Lappa-Manakou C, Ozgur Z, van Ijcken W, von Lindern M, Grosveld FG, Georgitsi M, Kleanthous M, Philipsen S, Patrinos GP.

Pharmacogenomics. 2012 Oct;13(13):1487-500. doi: 10.2217/pgs.12.125.

PMID:
23057549
24.

Sequential administration of the native TERT572 cryptic peptide enhances the immune response initiated by its optimized variant TERT(572Y) in cancer patients.

Vetsika EK, Papadimitraki E, Aggouraki D, Konsolakis G, Mela ME, Kotsakis A, Christou S, Patramani S, Alefantinou M, Kaskara A, Christophyllakis C, Kosmatopoulos K, Georgoulias V, Mavroudis D.

J Immunother. 2011 Nov-Dec;34(9):641-50. doi: 10.1097/CJI.0b013e31823284a6.

PMID:
21989412
25.

Clinical outcome of patients with various advanced cancer types vaccinated with an optimized cryptic human telomerase reverse transcriptase (TERT) peptide: results of an expanded phase II study.

Kotsakis A, Vetsika EK, Christou S, Hatzidaki D, Vardakis N, Aggouraki D, Konsolakis G, Georgoulias V, Christophyllakis Ch, Cordopatis P, Kosmatopoulos K, Mavroudis D.

Ann Oncol. 2012 Feb;23(2):442-9. doi: 10.1093/annonc/mdr396. Epub 2011 Aug 25.

PMID:
21873272
26.

Immunological responses in cancer patients after vaccination with the therapeutic telomerase-specific vaccine Vx-001.

Vetsika EK, Konsolakis G, Aggouraki D, Kotsakis A, Papadimitraki E, Christou S, Menez-Jamet J, Kosmatopoulos K, Georgoulias V, Mavroudis D.

Cancer Immunol Immunother. 2012 Feb;61(2):157-168. doi: 10.1007/s00262-011-1093-4. Epub 2011 Aug 20.

PMID:
21858533
27.

Growth hormone and adrenal response to intramuscular glucagon test and its relationship to IGF-1 production and left ventricular ejection fraction in adult B-thalassemia major patients.

De Sanctis V, Skordis N, Galati MC, Raiola G, Giovannini M, Candini G, Kaffe K, Savvides I, Christou S.

Pediatr Endocrinol Rev. 2011 Mar;8 Suppl 2:290-4.

PMID:
21705980
28.

Regeneration of three-way automobile catalysts using biodegradable metal chelating agent--S, S-ethylenediamine disuccinic acid (S, S-EDDS).

Subramanian B, Christou SY, Efstathiou AM, Namboodiri V, Dionysiou DD.

J Hazard Mater. 2011 Feb 28;186(2-3):999-1006. doi: 10.1016/j.jhazmat.2010.11.089. Epub 2010 Nov 27.

PMID:
21177030
29.

Compounds of the anthracycline family of antibiotics elevate human gamma-globin expression both in erythroid cultures and in a transgenic mouse model.

Spyrou P, Phylactides M, Lederer CW, Kithreotis L, Kirri A, Christou S, Kkolou E, Kanavakis E, Anagnou NP, Stamatoyannopoulos G, Kleanthous M.

Blood Cells Mol Dis. 2010 Mar-Apr;44(2):100-6. doi: 10.1016/j.bcmd.2009.10.008. Epub 2009 Nov 14.

PMID:
19914848
30.

Improved survival in thalassemia major patients on switching from desferrioxamine to combined chelation therapy with desferrioxamine and deferiprone.

Telfer PT, Warburton F, Christou S, Hadjigavriel M, Sitarou M, Kolnagou A, Angastiniotis M.

Haematologica. 2009 Dec;94(12):1777-8. doi: 10.3324/haematol.2009.009118. Epub 2009 Oct 8. No abstract available.

31.

An electronic infrastructure for research and treatment of the thalassemias and other hemoglobinopathies: the Euro-mediterranean ITHANET project.

Lederer CW, Basak AN, Aydinok Y, Christou S, El-Beshlawy A, Eleftheriou A, Fattoum S, Felice AE, Fibach E, Galanello R, Gambari R, Gavrila L, Giordano PC, Grosveld F, Hassapopoulou H, Hladka E, Kanavakis E, Locatelli F, Old J, Patrinos GP, Romeo G, Taher A, Traeger-Synodinos J, Vassiliou P, Villegas A, Voskaridou E, Wajcman H, Zafeiropoulos A, Kleanthous M.

Hemoglobin. 2009;33(3):163-76. doi: 10.1080/03630260903089177.

PMID:
19657830
32.

Effect of bisphosphonate treatment on bone mineral density in patients with thalassaemia major.

Skordis N, Ioannou YS, Kyriakou A, Savva SC, Efstathiou E, Savvides I, Christou S.

Pediatr Endocrinol Rev. 2008 Oct;6 Suppl 1:144-8.

PMID:
19337169
33.

Gender differences in the prevalence and severity of bone disease in thalassaemia.

Kyriakou A, Savva SC, Savvides I, Pangalou E, Ioannou YS, Christou S, Skordis N.

Pediatr Endocrinol Rev. 2008 Oct;6 Suppl 1:116-22.

PMID:
19337164
34.

Hb Agrinio [alpha29(B10)Le-->uPro (alpha2)] in combination with --(MED I). Results in a severe form of Hb H disease.

Felekis X, Phylactides M, Drousiotou A, Christou S, Kyrri A, Kyriakou K, Kalogerou E, Christopoulos G, Kleanthous M.

Hemoglobin. 2008;32(3):237-46. doi: 10.1080/03630260802004103.

PMID:
18473239
35.

Survival of medically treated thalassemia patients in Cyprus. Trends and risk factors over the period 1980-2004.

Telfer P, Coen PG, Christou S, Hadjigavriel M, Kolnakou A, Pangalou E, Pavlides N, Psiloines M, Simamonian K, Skordos G, Sitarou M, Angastiniotis M.

Haematologica. 2006 Sep;91(9):1187-92.

36.

The impact of genotype on endocrine complications in thalassaemia major.

Skordis N, Michaelidou M, Savva SC, Ioannou Y, Rousounides A, Kleanthous M, Skordos G, Christou S.

Eur J Haematol. 2006 Aug;77(2):150-6. Epub 2006 Jun 23.

PMID:
16800840
37.

Reactivation of an aged commercial three-way catalyst by oxalic and citric acid washing.

Christou SY, Birgersson H, Fierro JL, Efstathiou AM.

Environ Sci Technol. 2006 Mar 15;40(6):2030-6.

PMID:
16570632
38.

Update on fertility in thalassaemia major.

Skordis N, Petrikkos L, Toumba M, Hadjigavriel M, Sitarou M, Kolnakou A, Skordos G, Pangalou E, Christou S.

Pediatr Endocrinol Rev. 2004 Dec;2 Suppl 2:296-302. Review.

PMID:
16462715
39.

Quality of life in thalassemia.

Telfer P, Constantinidou G, Andreou P, Christou S, Modell B, Angastiniotis M.

Ann N Y Acad Sci. 2005;1054:273-82. Review.

PMID:
16339675
40.

Fertility in female patients with thalassemia.

Skordis N, Christou S, Koliou M, Pavlides N, Angastiniotis M.

J Pediatr Endocrinol Metab. 1998;11 Suppl 3:935-43.

PMID:
10091168
41.

Underexpression of the apolipoprotein E2 and E4 alleles in the Greek Cypriot population of Cyprus.

Cariolou MA, Kokkofitou A, Manoli P, Christou S, Karagrigoriou A, Middleton L.

Genet Epidemiol. 1995;12(5):489-97. Review.

PMID:
8557181

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