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Items: 1 to 50 of 88

1.

A rapid diagnostic test for human Visceral Leishmaniasis using novel Leishmania antigens in a Laser Direct-Write Lateral Flow Device.

Humbert MV, Costa LE, Katis I, Fonseca Ramos F, Sanchéz Machado A, Sones C, Ferraz Coelho EA, Christodoulides M.

Emerg Microbes Infect. 2019;8(1):1178-1185. doi: 10.1080/22221751.2019.1635430.

2.

Characterization of two putative Dichelobacter nodosus footrot vaccine antigens identifies the first lysozyme inhibitor in the genus.

Humbert MV, Jackson A, Orr CM, Tews I, Christodoulides M.

Sci Rep. 2019 Jul 11;9(1):10055. doi: 10.1038/s41598-019-46506-z.

3.

Use of Human Fallopian Tube Organ in Culture (FTOC) and Primary Fallopian Tube Epithelial Cells (FTEC) to Study the Biology of Neisseria gonorrhoeae Infection.

Álamos-Musre AS, Escobar A, Tapia CV, Christodoulides M, Rodas PI.

Methods Mol Biol. 2019;1997:377-402. doi: 10.1007/978-1-4939-9496-0_22.

PMID:
31119635
4.

Basic Methods for Examining Neisseria gonorrhoeae Interactions with Host Cells In Vitro.

Almonacid-Mendoza HL, Christodoulides M.

Methods Mol Biol. 2019;1997:281-299. doi: 10.1007/978-1-4939-9496-0_17.

PMID:
31119630
5.

Preparation of Lipooligosaccharide (LOS) from Neisseria gonorrhoeae.

Christodoulides M.

Methods Mol Biol. 2019;1997:87-96. doi: 10.1007/978-1-4939-9496-0_6.

PMID:
31119619
6.

Structure of the Recombinant Neisseria gonorrhoeae Adhesin Complex Protein (rNg-ACP) and Generation of Murine Antibodies with Bactericidal Activity against Gonococci.

Almonacid-Mendoza HL, Humbert MV, Dijokaite A, Cleary DW, Soo Y, Hung MC, Orr CM, Machelett MM, Tews I, Christodoulides M.

mSphere. 2018 Oct 10;3(5). pii: e00331-18. doi: 10.1128/mSphere.00331-18.

7.

The Growing Threat of Gonococcal Blindness.

Dolange V, Churchward CP, Christodoulides M, Snyder LAS.

Antibiotics (Basel). 2018 Jul 12;7(3). pii: E59. doi: 10.3390/antibiotics7030059.

8.

Neisseria gonorrhoeae employs two protein inhibitors to evade killing by human lysozyme.

Ragland SA, Humbert MV, Christodoulides M, Criss AK.

PLoS Pathog. 2018 Jul 5;14(7):e1007080. doi: 10.1371/journal.ppat.1007080. eCollection 2018 Jul.

10.

The meninges as barriers and facilitators for the movement of fluid, cells and pathogens related to the rodent and human CNS.

Weller RO, Sharp MM, Christodoulides M, Carare RO, Møllgård K.

Acta Neuropathol. 2018 Mar;135(3):363-385. doi: 10.1007/s00401-018-1809-z. Epub 2018 Jan 24. Review.

PMID:
29368214
11.

Neisseria gonorrhoeae Challenge Increases Matrix Metalloproteinase-8 Expression in Fallopian Tube Explants.

Juica NE, Rodas PI, Solar P, Borda P, Vargas R, Muñoz C, Paredes R, Christodoulides M, Velasquez LA.

Front Cell Infect Microbiol. 2017 Sep 6;7:399. doi: 10.3389/fcimb.2017.00399. eCollection 2017.

12.

Effect of Different Antibiotic Chemotherapies on Pseudomonas aeruginosa Infection In Vitro of Primary Human Corneal Fibroblast Cells.

Del Mar Cendra M, Christodoulides M, Hossain P.

Front Microbiol. 2017 Aug 22;8:1614. doi: 10.3389/fmicb.2017.01614. eCollection 2017.

13.

Structure of the Neisseria Adhesin Complex Protein (ACP) and its role as a novel lysozyme inhibitor.

Humbert MV, Awanye AM, Lian LY, Derrick JP, Christodoulides M.

PLoS Pathog. 2017 Jun 29;13(6):e1006448. doi: 10.1371/journal.ppat.1006448. eCollection 2017 Jun.

14.

Signaling Mediated by Toll-Like Receptor 5 Sensing of Pseudomonas aeruginosa Flagellin Influences IL-1β and IL-18 Production by Primary Fibroblasts Derived from the Human Cornea.

Cendra MDM, Christodoulides M, Hossain P.

Front Cell Infect Microbiol. 2017 Apr 19;7:130. doi: 10.3389/fcimb.2017.00130. eCollection 2017.

15.

Novel approaches to Neisseria meningitidis vaccine design.

Christodoulides M, Heckels J.

Pathog Dis. 2017 Apr 1;75(3). doi: 10.1093/femspd/ftx033. Review.

PMID:
28369428
16.

Modified Profile of Matrix Metalloproteinase 2 and 9 Production by Human Fallopian Tube Epithelial Cells After Infection In Vitro With Neisseria gonorrhoeae.

Rodas PI, Pérez D, Jauffret C, González Y, Carreño C, Tapia CV, Osorio E, Velasquez LA, Christodoulides M.

J Infect Dis. 2017 Feb 1;215(3):452-455. doi: 10.1093/infdis/jiw568.

17.

Viral Inhibition of Bacterial Phagocytosis by Human Macrophages: Redundant Role of CD36.

Cooper GE, Pounce ZC, Wallington JC, Bastidas-Legarda LY, Nicholas B, Chidomere C, Robinson EC, Martin K, Tocheva AS, Christodoulides M, Djukanovic R, Wilkinson TM, Staples KJ.

PLoS One. 2016 Oct 4;11(10):e0163889. doi: 10.1371/journal.pone.0163889. eCollection 2016.

18.

Vaccines for piscirickettsiosis (salmonid rickettsial septicaemia, SRS): the Chile perspective.

Maisey K, Montero R, Christodoulides M.

Expert Rev Vaccines. 2017 Mar;16(3):215-228. doi: 10.1080/14760584.2017.1244483. Epub 2016 Oct 12. Review.

PMID:
27690686
19.

Vaccine Potential and Diversity of the Putative Cell Binding Factor (CBF, NMB0345/NEIS1825) Protein of Neisseria meningitidis.

Humbert MV, Hung MC, Phillips R, Akoto C, Hill A, Tan WM, Heckels JE, Christodoulides M.

PLoS One. 2016 Aug 9;11(8):e0160403. doi: 10.1371/journal.pone.0160403. eCollection 2016.

20.

The NarE protein of Neisseria gonorrhoeae catalyzes ADP-ribosylation of several ADP-ribose acceptors despite an N-terminal deletion.

Rodas PI, Álamos-Musre AS, Álvarez FP, Escobar A, Tapia CV, Osorio E, Otero C, Calderón IL, Fuentes JA, Gil F, Paredes-Sabja D, Christodoulides M.

FEMS Microbiol Lett. 2016 Sep;363(17). pii: fnw181. doi: 10.1093/femsle/fnw181. Epub 2016 Jul 26.

21.

Co-Transcriptomes of Initial Interactions In Vitro between Streptococcus Pneumoniae and Human Pleural Mesothelial Cells.

Heath CJ, del Mar Cendra M, Watson A, Auger JP, Pandey A, Tighe P, Christodoulides M.

PLoS One. 2015 Nov 13;10(11):e0142773. doi: 10.1371/journal.pone.0142773. eCollection 2015.

22.

Interactions of Streptococcus suis serotype 2 with human meningeal cells and astrocytes.

Auger JP, Christodoulides M, Segura M, Xu J, Gottschalk M.

BMC Res Notes. 2015 Oct 26;8:607. doi: 10.1186/s13104-015-1581-2.

23.

Vaccine potential of bacterial macrophage infectivity potentiator (MIP)-like peptidyl prolyl cis/trans isomerase (PPIase) proteins.

Humbert MV, Almonacid Mendoza HL, Jackson AC, Hung MC, Bielecka MK, Heckels JE, Christodoulides M.

Expert Rev Vaccines. 2015;14(12):1633-49. doi: 10.1586/14760584.2015.1095638. Epub 2015 Oct 15. Review.

PMID:
26468663
24.

Draft Genome Sequence of Dichelobacter nodosus ATCC 25549, Strain VPI 2340 [11342], a Bacterium Causing Footrot in Sheep.

Jackson A, Humbert MV, Pandey A, Bratcher H, Christodoulides M.

Genome Announc. 2015 Sep 24;3(5). pii: e01002-15. doi: 10.1128/genomeA.01002-15.

25.

A putative amino acid ABC transporter substrate-binding protein, NMB1612, from Neisseria meningitidis, induces murine bactericidal antibodies against meningococci expressing heterologous NMB1612 proteins.

Hung MC, Humbert MV, Laver JR, Phillips R, Heckels JE, Christodoulides M.

Vaccine. 2015 Aug 26;33(36):4486-94. doi: 10.1016/j.vaccine.2015.07.032. Epub 2015 Jul 21.

PMID:
26207592
26.

Pattern recognition receptors in microbial keratitis.

Taube MA, del Mar Cendra M, Elsahn A, Christodoulides M, Hossain P.

Eye (Lond). 2015 Nov;29(11):1399-415. doi: 10.1038/eye.2015.118. Epub 2015 Jul 10. Review.

27.

Current methods for capsular typing of Streptococcus pneumoniae.

Jauneikaite E, Tocheva AS, Jefferies JM, Gladstone RA, Faust SN, Christodoulides M, Hibberd ML, Clarke SC.

J Microbiol Methods. 2015 Jun;113:41-9. doi: 10.1016/j.mimet.2015.03.006. Epub 2015 Mar 25. Review.

PMID:
25819558
28.

Recombinant protein truncation strategy for inducing bactericidal antibodies to the macrophage infectivity potentiator protein of Neisseria meningitidis and circumventing potential cross-reactivity with human FK506-binding proteins.

Bielecka MK, Devos N, Gilbert M, Hung MC, Weynants V, Heckels JE, Christodoulides M.

Infect Immun. 2015 Feb;83(2):730-42. doi: 10.1128/IAI.01815-14. Epub 2014 Dec 1.

29.

Neisseria proteomics for antigen discovery and vaccine development.

Christodoulides M.

Expert Rev Proteomics. 2014 Oct;11(5):573-91. doi: 10.1586/14789450.2014.938640. Epub 2014 Jul 12. Review.

PMID:
25017717
30.

Immuno-proteomic analysis of human immune responses to experimental Neisseria meningitidis outer membrane vesicle vaccines identifies potential cross-reactive antigens.

Williams JN, Weynants V, Poolman JT, Heckels JE, Christodoulides M.

Vaccine. 2014 Mar 5;32(11):1280-6. doi: 10.1016/j.vaccine.2013.12.070. Epub 2014 Jan 30.

PMID:
24486354
31.

Potential of the adhesin complex protein of Neisseria meningitidis for next-generation meningococcal vaccines.

Hung MC, Heckels JE, Christodoulides M.

Expert Rev Vaccines. 2013 Sep;12(9):981-4. doi: 10.1586/14760584.2013.828881. No abstract available.

PMID:
24053391
32.

Distribution of carried pneumococcal clones in UK children following the introduction of the 7-valent pneumococcal conjugate vaccine: a 3-year cross-sectional population based analysis.

Tocheva AS, Jefferies JM, Christodoulides M, Faust SN, Clarke SC.

Vaccine. 2013 Jun 28;31(31):3187-90. doi: 10.1016/j.vaccine.2013.04.075. Epub 2013 May 13.

PMID:
23680442
33.

Genome-based bacterial vaccines: current state and future outlook.

Schubert-Unkmeir A, Christodoulides M.

BioDrugs. 2013 Oct;27(5):419-30. doi: 10.1007/s40259-013-0034-5. Review.

PMID:
23588477
34.

Immunization with recombinant Chaperonin60 (Chp60) outer membrane protein induces a bactericidal antibody response against Neisseria meningitidis.

Phillips R, Williams JN, Tan WM, Bielecka MK, Thompson H, Hung MC, Heckels JE, Christodoulides M.

Vaccine. 2013 May 24;31(22):2584-90. doi: 10.1016/j.vaccine.2013.03.033. Epub 2013 Apr 6.

PMID:
23566947
35.

The adhesin complex protein (ACP) of Neisseria meningitidis is a new adhesin with vaccine potential.

Hung MC, Heckels JE, Christodoulides M.

MBio. 2013 Feb 26;4(2). pii: e00041-13. doi: 10.1128/mBio.00041-13.

36.

The biology of Neisseria adhesins.

Hung MC, Christodoulides M.

Biology (Basel). 2013 Jul 29;2(3):1054-109. doi: 10.3390/biology2031054.

37.

Effective plasmid DNA and small interfering RNA delivery to diseased human brain microvascular endothelial cells.

Slanina H, Schmutzler M, Christodoulides M, Kim KS, Schubert-Unkmeir A.

J Mol Microbiol Biotechnol. 2012;22(4):245-57. doi: 10.1159/000342909. Epub 2012 Oct 4.

PMID:
23036990
38.

Group B Streptococcus interactions with human meningeal cells and astrocytes in vitro.

Alkuwaity K, Taylor A, Heckels JE, Doran KS, Christodoulides M.

PLoS One. 2012;7(8):e42660. doi: 10.1371/journal.pone.0042660. Epub 2012 Aug 10.

39.

Differential expression of extracellular matrix components in the Fallopian tubes throughout the menstrual cycle.

Diaz PS, Solar PA, Juica NE, Orihuela PA, Cardenas H, Christodoulides M, Vargas R, Velasquez LA.

Reprod Biol Endocrinol. 2012 Aug 16;10:56. doi: 10.1186/1477-7827-10-56.

40.

Coadministration of the cyanobacterial lipopolysaccharide antagonist CyP with antibiotic inhibits cytokine production by an in vitro meningitis model infected with Neisseria meningitidis.

Oliver R, Staples KJ, Heckels J, Rossetti C, Molteni M, Christodoulides M.

J Antimicrob Chemother. 2012 May;67(5):1145-54. doi: 10.1093/jac/dks031. Epub 2012 Feb 14.

PMID:
22334603
41.

Neisseria gonorrhoeae pilus attenuates cytokine response of human fallopian tube explants.

Velasquez L, García K, Morales F, Heckels JE, Orihuela P, Rodas PI, Christodoulides M, Cardenas H.

J Biomed Biotechnol. 2012;2012:491298. doi: 10.1155/2012/491298. Epub 2012 Jan 24.

42.

A DNA vaccine strategy for effective antibody induction to pathogen-derived antigens.

Rice J, Christodoulides M.

Methods Mol Biol. 2012;799:405-19. doi: 10.1007/978-1-61779-346-2_22.

PMID:
21993657
43.

Analysis of the immune response to Neisseria meningitidis using a proteomics approach.

Williams JN, Christodoulides M, Heckels JE.

Methods Mol Biol. 2012;799:343-60. doi: 10.1007/978-1-61779-346-2_20.

PMID:
21993655
44.

The Neisseria meningitidis macrophage infectivity potentiator protein induces cross-strain serum bactericidal activity and is a potential serogroup B vaccine candidate.

Hung MC, Salim O, Williams JN, Heckels JE, Christodoulides M.

Infect Immun. 2011 Sep;79(9):3784-91. doi: 10.1128/IAI.05019-11. Epub 2011 Jun 27.

45.

Declining serotype coverage of new pneumococcal conjugate vaccines relating to the carriage of Streptococcus pneumoniae in young children.

Tocheva AS, Jefferies JM, Rubery H, Bennett J, Afimeke G, Garland J, Christodoulides M, Faust SN, Clarke SC.

Vaccine. 2011 Jun 10;29(26):4400-4. doi: 10.1016/j.vaccine.2011.04.004. Epub 2011 Apr 17.

PMID:
21504773
46.

Nitric oxide is not involved in Neisseria gonorrhoeae-induced cellular damage of human Fallopian tubes in vitro.

García KP, Rubilar PS, Vargas MF, Cárdenas H, Rios MA, Orihuela PA, Vargas RH, Fuhrer J, Heckels JE, Christodoulides M, Velásquez LA.

Biol Res. 2010;43(1):39-50. doi: /S0716-97602010000100006. Epub 2010 May 7.

47.

Identification of novel pneumolysin alleles from paediatric carriage isolates of Streptococcus pneumoniae.

Jefferies JM, Tocheva AS, Rubery H, Bennett J, Garland J, Christodoulides M, Faust SN, Smith A, Mitchell TJ, Clarke SC.

J Med Microbiol. 2010 Jul;59(Pt 7):808-14. doi: 10.1099/jmm.0.018663-0. Epub 2010 Mar 25.

PMID:
20339017
48.

Increase in serotype 6C pneumococcal carriage, United Kingdom.

Tocheva AS, Jefferies JM, Christodoulides M, Faust SN, Clarke SC.

Emerg Infect Dis. 2010 Jan;16(1):154-5. doi: 10.3201/eid1601.090650. No abstract available.

49.

Immunoproteomic analysis of the development of natural immunity in subjects colonized by Neisseria meningitidis reveals potential vaccine candidates.

Williams JN, Skipp PJ, O'Connor CD, Christodoulides M, Heckels JE.

Infect Immun. 2009 Nov;77(11):5080-9. doi: 10.1128/IAI.00701-09. Epub 2009 Sep 8.

50.

Neuropeptide alpha-MSH exerts pro-inflammatory effects on Neisseria meningitidis infection in vitro.

Kumar P, Williams JN, Durkin KL, Heckels JE, Friedmann PS, Healy E, Christodoulides M.

Inflamm Res. 2010 Feb;59(2):105-13. doi: 10.1007/s00011-009-0076-9. Epub 2009 Aug 15.

PMID:
19685205

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