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Items: 1 to 50 of 156

1.

Synthesis of Quinolinone Alkaloids via Aryne Insertions into Unsymmetric Imides in Flow.

Schwan J, Kleoff M, Hartmayer B, Heretsch P, Christmann M.

Org Lett. 2018 Nov 27. doi: 10.1021/acs.orglett.8b03392. [Epub ahead of print]

PMID:
30479132
2.

Synthesis of (+)-Darwinolide, a Biofilm-Penetrating Anti-MRSA Agent.

Siemon T, Steinhauer S, Christmann M.

Angew Chem Int Ed Engl. 2018 Nov 19. doi: 10.1002/anie.201813142. [Epub ahead of print]

PMID:
30451352
3.

A restrictive ventilatory pattern is common in patients with univentricular heart after Fontan palliation and associated with a reduced exercise capacity and quality of life.

Callegari A, Neidenbach R, Milanesi O, Castaldi B, Christmann M, Ono M, Müller J, Ewert P, Hager A.

Congenit Heart Dis. 2018 Oct 30. doi: 10.1111/chd.12694. [Epub ahead of print]

PMID:
30378270
4.

Temozolomide induces senescence and repression of DNA repair pathways in glioblastoma cells via activation of ATR-CHK1, p21, and NF-kB.

Aasland D, Götzinger L, Hauck L, Berte N, Meyer J, Effenberger M, Schneider S, Reuber EE, Roos WP, Tomicic MT, Kaina B, Christmann M.

Cancer Res. 2018 Oct 25. pii: canres.1733.2018. doi: 10.1158/0008-5472.CAN-18-1733. [Epub ahead of print]

PMID:
30361254
5.

[Lipid profile and cardiovascular risk of participants in the lipid measurement program in the industrial park in Höchst].

Christmann M, Rosada A, Ferlinz K, Bramlage P, Steinhagen-Thiessen E.

Herz. 2018 Sep 28. doi: 10.1007/s00059-018-4746-7. [Epub ahead of print] German.

PMID:
30267118
6.

Towards a comprehensive understanding of the structural dynamics of a bacterial diterpene synthase during catalysis.

Driller R, Janke S, Fuchs M, Warner E, Mhashal AR, Major DT, Christmann M, Brück T, Loll B.

Nat Commun. 2018 Sep 28;9(1):3971. doi: 10.1038/s41467-018-06325-8.

7.

Differential Effects of Integrin αv Knockdown and Cilengitide on Sensitization of Triple-Negative Breast Cancer and Melanoma Cells to Microtubule Poisons.

Stojanović N, Dekanić A, Paradžik M, Majhen D, Ferenčak K, Ruščić J, Bardak I, Supina C, Tomicic MT, Christmann M, Osmak M, Ambriović-Ristov A.

Mol Pharmacol. 2018 Dec;94(6):1334-1351. doi: 10.1124/mol.118.113027. Epub 2018 Sep 27.

PMID:
30262596
8.

Synthesis of Highly Enantioenriched Propelladienes and their Application as Ligands in Asymmetric Rh-Catalyzed 1,4-Additions.

Pecchioli T, Christmann M.

Org Lett. 2018 Sep 7;20(17):5256-5259. doi: 10.1021/acs.orglett.8b02204. Epub 2018 Aug 14.

PMID:
30105910
9.

Synthesis of Enantioenriched Bromohydrins via Divergent Reactions of Racemic Intermediates from Anchimeric Oxygen Borrowing.

Cao YM, Lentz D, Christmann M.

J Am Chem Soc. 2018 Aug 29;140(34):10677-10681. doi: 10.1021/jacs.8b06432. Epub 2018 Aug 16.

PMID:
30099869
10.

Enabling strategies for step efficient syntheses.

Schwan J, Christmann M.

Chem Soc Rev. 2018 Oct 29;47(21):7985-7995. doi: 10.1039/c8cs00399h. Review.

PMID:
30059093
11.

Inherent and toxicant-provoked reduction in DNA repair capacity: A key mechanism for personalized risk assessment, cancer prevention and intervention, and response to therapy.

Kaina B, Izzotti A, Xu J, Christmann M, Pulliero A, Zhao X, Dobreanu M, Au WW.

Int J Hyg Environ Health. 2018 Aug;221(7):993-1006. doi: 10.1016/j.ijheh.2018.07.003. Epub 2018 Jul 21. Review.

PMID:
30041861
12.

TRPC4/TRPC5 channels mediate adverse reaction to the cancer cell cytotoxic agent (-)-Englerin A.

Cheung SY, Henrot M, Al-Saad M, Baumann M, Muller H, Unger A, Rubaiy HN, Mathar I, Dinkel K, Nussbaumer P, Klebl B, Freichel M, Rode B, Trainor S, Clapcote SJ, Christmann M, Waldmann H, Abbas SK, Beech DJ, Vasudev NS.

Oncotarget. 2018 Jul 3;9(51):29634-29643. doi: 10.18632/oncotarget.25659. eCollection 2018 Jul 3.

13.

Risk factor analysis for a complicated postoperative course after neonatal arterial switch operation: The role of troponin T.

Christmann M, Wipf A, Dave H, Quandt D, Niesse O, Deisenberg M, Hersberger M, Kretschmar O, Knirsch W.

Congenit Heart Dis. 2018 Jul;13(4):594-601. doi: 10.1111/chd.12615. Epub 2018 Jul 17.

PMID:
30019379
14.

Mechanistic Studies on the Organocatalytic α-Chlorination of Aldehydes: The Role and Nature of Off-Cycle Intermediates.

Ponath S, Menger M, Grothues L, Weber M, Lentz D, Strohmann C, Christmann M.

Angew Chem Int Ed Engl. 2018 Sep 3;57(36):11683-11687. doi: 10.1002/anie.201806261. Epub 2018 Aug 3.

PMID:
29999220
15.

Sensitization of colorectal cancer cells to irinotecan by the Survivin inhibitor LLP3 depends on XAF1 proficiency in the context of mutated p53.

Steigerwald C, Rasenberger B, Christmann M, Tomicic MT.

Arch Toxicol. 2018 Aug;92(8):2645-2648. doi: 10.1007/s00204-018-2240-x. Epub 2018 Jun 8.

PMID:
29947891
16.

Synthesis of (+)-Vitepyrroloid A and (+)-Vitepyrroloid B by Late-Stage Ni-Catalyzed C(sp2)-C(sp3) Cross-Electrophile Coupling.

Menger M, Lentz D, Christmann M.

J Org Chem. 2018 Jun 15;83(12):6793-6797. doi: 10.1021/acs.joc.8b00882. Epub 2018 May 31.

PMID:
29774741
17.

A General One-Pot Synthesis of 2H-Indazoles Using an Organophosphorus-Silane System.

Schoene J, Bel Abed H, Schmieder P, Christmann M, Nazaré M.

Chemistry. 2018 Jun 26;24(36):9090-9100. doi: 10.1002/chem.201800763. Epub 2018 Jun 6.

PMID:
29644761
18.

Bioinspired synthesis of pentacyclic onocerane triterpenoids.

Bartels F, Hong YJ, Ueda D, Weber M, Sato T, Tantillo DJ, Christmann M.

Chem Sci. 2017 Dec 1;8(12):8285-8290. doi: 10.1039/c7sc03903d. Epub 2017 Oct 16.

19.

Does Oral Implant Design Affect Marginal Bone Loss? Results of a Parallel-Group Randomized Controlled Equivalence Trial.

Spies BC, Bateli M, Ben Rahal G, Christmann M, Vach K, Kohal RJ.

Biomed Res Int. 2018 Jan 31;2018:8436437. doi: 10.1155/2018/8436437. eCollection 2018.

20.

Loss of Wilms tumor 1 protein is a marker for apoptosis in response to replicative stress in leukemic cells.

Pons M, Reichardt CM, Hennig D, Nathan A, Kiweler N, Stocking C, Wichmann C, Christmann M, Butter F, Reichardt S, Schneider G, Heinzel T, Englert C, Hartkamp J, Krämer OH, Mahendrarajah N.

Arch Toxicol. 2018 Jun;92(6):2119-2135. doi: 10.1007/s00204-018-2202-3. Epub 2018 Mar 27.

PMID:
29589053
21.

HDAC1 and HDAC2 integrate checkpoint kinase phosphorylation and cell fate through the phosphatase-2A subunit PR130.

Göder A, Emmerich C, Nikolova T, Kiweler N, Schreiber M, Kühl T, Imhof D, Christmann M, Heinzel T, Schneider G, Krämer OH.

Nat Commun. 2018 Feb 22;9(1):764. doi: 10.1038/s41467-018-03096-0.

22.

Aortopulmonary collaterals in neonates with d-transposition of the great arteries - Clinical significance early after arterial switch operation.

Wipf A, Christmann M, Navarini-Meury S, Dave H, Quandt D, Knirsch W, Kretschmar O.

Int J Cardiol. 2018 May 1;258:237-242. doi: 10.1016/j.ijcard.2018.01.132. Epub 2018 Feb 2.

PMID:
29444748
23.

Prognostic value of troponin in infants with hypoplastic left heart syndrome between Stage I and II of palliation.

Christmann M, Valsangiacomo Büchel ER, Dave H, Klauwer D, Cavigelli-Brunner A.

Ann Pediatr Cardiol. 2018 Jan-Apr;11(1):56-59. doi: 10.4103/apc.APC_113_17.

24.

Synthesis of Thelepamide via Catalyst-Controlled 1,4-Addition of Cysteine Derivatives and Structure Revision of Thelepamide.

Seitz T, Millán RE, Lentz D, Jiménez C, Rodríguez J, Christmann M.

Org Lett. 2018 Feb 2;20(3):594-597. doi: 10.1021/acs.orglett.7b03706. Epub 2018 Jan 10.

PMID:
29320197
25.

Synthesis and Structure Revision of Dichrocephones A and B.

Schmiedel VM, Hong YJ, Lentz D, Tantillo DJ, Christmann M.

Angew Chem Int Ed Engl. 2018 Feb 23;57(9):2419-2422. doi: 10.1002/anie.201711766. Epub 2018 Jan 16.

PMID:
29251825
26.

TNF Tolerance in Monocytes and Macrophages: Characteristics and Molecular Mechanisms.

Huber R, Bikker R, Welz B, Christmann M, Brand K.

J Immunol Res. 2017;2017:9570129. doi: 10.1155/2017/9570129. Epub 2017 Nov 8. Review.

27.

Identification of an (-)-englerin A analogue, which antagonizes (-)-englerin A at TRPC1/4/5 channels.

Rubaiy HN, Seitz T, Hahn S, Choidas A, Habenberger P, Klebl B, Dinkel K, Nussbaumer P, Waldmann H, Christmann M, Beech DJ.

Br J Pharmacol. 2018 Mar;175(5):830-839. doi: 10.1111/bph.14128. Epub 2018 Jan 25.

PMID:
29247460
28.

Na+ entry through heteromeric TRPC4/C1 channels mediates (-)Englerin A-induced cytotoxicity in synovial sarcoma cells.

Muraki K, Ohnishi K, Takezawa A, Suzuki H, Hatano N, Muraki Y, Hamzah N, Foster R, Waldmann H, Nussbaumer P, Christmann M, Bon RS, Beech DJ.

Sci Rep. 2017 Dec 5;7(1):16988. doi: 10.1038/s41598-017-17303-3.

29.

Repair gene O6 -methylguanine-DNA methyltransferase is controlled by SP1 and up-regulated by glucocorticoids, but not by temozolomide and radiation.

Aasland D, Reich TR, Tomicic MT, Switzeny OJ, Kaina B, Christmann M.

J Neurochem. 2018 Jan;144(2):139-151. doi: 10.1111/jnc.14262. Epub 2018 Jan 1.

PMID:
29164620
30.

Bioactive natural products.

Christmann M.

Bioorg Med Chem. 2017 Nov 15;25(22):6087. doi: 10.1016/j.bmc.2017.10.034. No abstract available.

PMID:
29110815
31.

TNF phase III signalling in tolerant cells is tightly controlled by A20 and CYLD.

Bikker R, Christmann M, Preuß K, Welz B, Friesenhagen J, Dittrich-Breiholz O, Huber R, Brand K.

Cell Signal. 2017 Sep;37:123-135. doi: 10.1016/j.cellsig.2017.06.009. Epub 2017 Jun 16.

PMID:
28629782
32.

Asymmetric Synthesis of Carbocyclic Propellanes.

Schneider LM, Schmiedel VM, Pecchioli T, Lentz D, Merten C, Christmann M.

Org Lett. 2017 May 5;19(9):2310-2313. doi: 10.1021/acs.orglett.7b00836. Epub 2017 Apr 26.

PMID:
28445060
33.

Picomolar, selective, and subtype-specific small-molecule inhibition of TRPC1/4/5 channels.

Rubaiy HN, Ludlow MJ, Henrot M, Gaunt HJ, Miteva K, Cheung SY, Tanahashi Y, Hamzah N, Musialowski KE, Blythe NM, Appleby HL, Bailey MA, McKeown L, Taylor R, Foster R, Waldmann H, Nussbaumer P, Christmann M, Bon RS, Muraki K, Beech DJ.

J Biol Chem. 2017 May 19;292(20):8158-8173. doi: 10.1074/jbc.M116.773556. Epub 2017 Mar 21.

34.

Synthesis of (+)-Greek Tobacco Lactone via a Diastereoablative Epoxidation and a Selenium-Catalyzed Oxidative Cyclization.

Leisering S, Riaño I, Depken C, Gross LJ, Weber M, Lentz D, Zimmer R, Stark CB, Breder A, Christmann M.

Org Lett. 2017 Mar 17;19(6):1478-1481. doi: 10.1021/acs.orglett.7b00484. Epub 2017 Mar 3.

PMID:
28257212
35.

Epigenetic silencing of XAF1 in high-grade gliomas is associated with IDH1 status and improved clinical outcome.

Reich TR, Switzeny OJ, Renovanz M, Sommer C, Kaina B, Christmann M, Tomicic MT.

Oncotarget. 2017 Feb 28;8(9):15071-15084. doi: 10.18632/oncotarget.14748.

36.

Acoustic and Auditory Perception Effects of the Voice Therapy Technique Finger Kazoo in Adult Women.

Christmann MK, Cielo CA.

J Voice. 2017 May;31(3):390.e9-390.e15. doi: 10.1016/j.jvoice.2016.09.025. Epub 2016 Nov 7.

PMID:
27839707
37.

Analysis of the interplay between all-trans retinoic acid and histone deacetylase inhibitors in leukemic cells.

Noack K, Mahendrarajah N, Hennig D, Schmidt L, Grebien F, Hildebrand D, Christmann M, Kaina B, Sellmer A, Mahboobi S, Kubatzky K, Heinzel T, Krämer OH.

Arch Toxicol. 2017 May;91(5):2191-2208. doi: 10.1007/s00204-016-1878-5. Epub 2016 Nov 2.

38.

Closure of coronary artery fistula in childhood: treatment techniques and long-term follow-up.

Christmann M, Hoop R, Dave H, Quandt D, Knirsch W, Kretschmar O.

Clin Res Cardiol. 2017 Mar;106(3):211-218. doi: 10.1007/s00392-016-1041-6. Epub 2016 Oct 11.

PMID:
27730300
39.

Adaptive upregulation of DNA repair genes following benzo(a)pyrene diol epoxide protects against cell death at the expense of mutations.

Christmann M, Boisseau C, Kitzinger R, Berac C, Allmann S, Sommer T, Aasland D, Kaina B, Tomicic MT.

Nucleic Acids Res. 2016 Dec 15;44(22):10727-10743. Epub 2016 Sep 30.

40.

Long-term follow-up of interventional closure of atrial septal defect using the Solysafe™ Septal Occluder.

Knirsch W, Quandt D, Christmann M, Hübler M, Kretschmar O.

Int J Cardiol. 2016 Nov 15;223:645-646. doi: 10.1016/j.ijcard.2016.08.074. Epub 2016 Aug 5. No abstract available.

PMID:
27565843
41.

Organophosphorus-mediated N-N bond formation: facile access to 3-amino-2H-indazoles.

Bel Abed H, Schoene J, Christmann M, Nazaré M.

Org Biomol Chem. 2016 Sep 28;14(36):8520-8. doi: 10.1039/c6ob01544a. Epub 2016 Aug 19.

PMID:
27541713
42.

Integrin αVβ3 silencing sensitizes malignant glioma cells to temozolomide by suppression of homologous recombination repair.

Christmann M, Diesler K, Majhen D, Steigerwald C, Berte N, Freund H, Stojanović N, Kaina B, Osmak M, Ambriović-Ristov A, Tomicic MT.

Oncotarget. 2017 Apr 25;8(17):27754-27771. doi: 10.18632/oncotarget.10897.

43.

Evaluating long-term cellular effects of the arsenic species thio-DMA(V): qPCR-based gene expression as screening tool.

Ebert F, Thomann M, Witt B, Müller SM, Meyer S, Weber T, Christmann M, Schwerdtle T.

J Trace Elem Med Biol. 2016 Sep;37:78-84. doi: 10.1016/j.jtemb.2016.06.004. Epub 2016 Jun 2.

PMID:
27320638
44.

Mechanistic Characterisation of Two Sesquiterpene Cyclases from the Plant Pathogenic Fungus Fusarium fujikuroi.

Burkhardt I, Siemon T, Henrot M, Studt L, Rösler S, Tudzynski B, Christmann M, Dickschat JS.

Angew Chem Int Ed Engl. 2016 Jul 18;55(30):8748-51. doi: 10.1002/anie.201603782. Epub 2016 Jun 13.

PMID:
27294564
45.

One-Pot Synthesis of 5-Hydroxy-4H-1,3-thiazin-4-ones: Structure Revision, Synthesis, and NMR Shift Dependence of Thiasporine A.

Seitz T, Fu P, Haut FL, Adam L, Habicht M, Lentz D, MacMillan JB, Christmann M.

Org Lett. 2016 Jul 1;18(13):3070-3. doi: 10.1021/acs.orglett.6b01166. Epub 2016 Jun 10.

PMID:
27286418
46.

MGMT promoter methylation determined by HRM in comparison to MSP and pyrosequencing for predicting high-grade glioma response.

Switzeny OJ, Christmann M, Renovanz M, Giese A, Sommer C, Kaina B.

Clin Epigenetics. 2016 May 5;8:49. doi: 10.1186/s13148-016-0204-7. eCollection 2016.

47.

Effect of Vocal Fry on Voice and on Velopharyngeal Sphincter.

Elias VS, Cielo CA, Jotz GP, Christmann MK.

Int Arch Otorhinolaryngol. 2016 Apr;20(2):156-62. doi: 10.1055/s-0035-1569144. Epub 2015 Dec 15.

48.

The DenA/DEN1 Interacting Phosphatase DipA Controls Septa Positioning and Phosphorylation-Dependent Stability of Cytoplasmatic DenA/DEN1 during Fungal Development.

Schinke J, Kolog Gulko M, Christmann M, Valerius O, Stumpf SK, Stirz M, Braus GH.

PLoS Genet. 2016 Mar 24;12(3):e1005949. doi: 10.1371/journal.pgen.1005949. eCollection 2016 Mar.

49.

Impulse Oscillometry as a Predictor of Asthma Exacerbations in Young Children.

Schulze J, Biedebach S, Christmann M, Herrmann E, Voss S, Zielen S.

Respiration. 2016;91(2):107-14. doi: 10.1159/000442448. Epub 2016 Jan 13.

50.

Respiratory Muscle Strength, Sound Pressure Level, and Vocal Acoustic Parameters and Waist Circumference of Children With Different Nutritional Status.

Pascotini Fdos S, Ribeiro VV, Christmann MK, Tomasi LL, Dellazzana AA, Haeffner LS, Cielo CA.

J Voice. 2016 Jan;30(1):30-5. doi: 10.1016/j.jvoice.2015.02.006. Epub 2015 Dec 10.

PMID:
26685055

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