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Individuals with CYP2C8 and CYP2C9 reduced metabolism haplotypes self-adjusted ibuprofen dose in the Coriell Personalized Medicine Collaborative.

Zajic SC, Jarvis JP, Zhang P, Rajula KD, Brangan A, Brenner R, Dempsey MP, Christman MF.

Pharmacogenet Genomics. 2019 Apr;29(3):49-57. doi: 10.1097/FPC.0000000000000364.


Precision Military Medicine: Conducting a multi-site clinical utility study of genomic and lifestyle risk factors in the United States Air Force.

Delaney SK, Brenner R, Schmidlen TJ, Dempsey MP, London KE, Gordon ES, Bellafante M, Nasuti A, Scheinfeldt LB, Rajula KD, Jose L, Jarvis JP, Gerry NP, Christman MF.

NPJ Genom Med. 2017 Jan 19;2:2. doi: 10.1038/s41525-016-0004-1. eCollection 2017.


Clinical pharmacogenomics: patient perspectives of pharmacogenomic testing and the incidence of actionable test results in a chronic disease cohort.

Mukherjee C, Sweet KM, Luzum JA, Abdel-Rasoul M, Christman MF, Kitzmiller JP.

Per Med. 2017 Sep;14(5):383-388. doi: 10.2217/pme-2017-0022. Epub 2017 Sep 1.


CYP2D6 Genetic Variation and Beta-Blocker Maintenance Dose in Patients with Heart Failure.

Luzum JA, Sweet KM, Binkley PF, Schmidlen TJ, Jarvis JP, Christman MF, Sadee W, Kitzmiller JP.

Pharm Res. 2017 Aug;34(8):1615-1625. doi: 10.1007/s11095-017-2104-8. Epub 2017 Feb 8.


A randomized trial Examining The Impact Of Communicating Genetic And Lifestyle Risks For Obesity.

Wang C, Gordon ES, Norkunas T, Wawak L, Liu CT, Winter M, Kasper RS, Christman MF, Green RC, Bowen DJ.

Obesity (Silver Spring). 2016 Dec;24(12):2481-2490. doi: 10.1002/oby.21661.


Challenges in Translating GWAS Results to Clinical Care.

Scheinfeldt LB, Schmidlen TJ, Gerry NP, Christman MF.

Int J Mol Sci. 2016 Aug 4;17(8). pii: E1267. doi: 10.3390/ijms17081267.


Encouraging physician adoption of genetic testing for precision medicine.

Delaney SK, Christman MF.

Per Med. 2016 May;13(3):201-204. doi: 10.2217/pme-2016-0005. Epub 2016 Mar 22. No abstract available.


An expanded pharmacogenomics warfarin dosing table with utility in generalised dosing guidance.

Shahabi P, Scheinfeldt LB, Lynch DE, Schmidlen TJ, Perreault S, Keller MA, Kasper R, Wawak L, Jarvis JP, Gerry NP, Gordon ES, Christman MF, Dubé MP, Gharani N.

Thromb Haemost. 2016 Aug 1;116(2):337-48. doi: 10.1160/TH15-12-0955. Epub 2016 Apr 28.


Toward clinical genomics in everyday medicine: perspectives and recommendations.

Delaney SK, Hultner ML, Jacob HJ, Ledbetter DH, McCarthy JJ, Ball M, Beckman KB, Belmont JW, Bloss CS, Christman MF, Cosgrove A, Damiani SA, Danis T, Delledonne M, Dougherty MJ, Dudley JT, Faucett WA, Friedman JR, Haase DH, Hays TS, Heilsberg S, Huber J, Kaminsky L, Ledbetter N, Lee WH, Levin E, Libiger O, Linderman M, Love RL, Magnus DC, Martland A, McClure SL, Megill SE, Messier H, Nussbaum RL, Palaniappan L, Patay BA, Popovich BW, Quackenbush J, Savant MJ, Su MM, Terry SF, Tucker S, Wong WT, Green RC.

Expert Rev Mol Diagn. 2016;16(5):521-32. doi: 10.1586/14737159.2016.1146593. Epub 2016 Feb 24.


Direct-to-consumer genetic testing: Perspectives on its value in healthcare.

Delaney SK, Christman MF.

Clin Pharmacol Ther. 2016 Feb;99(2):146-8. doi: 10.1002/cpt.287. Epub 2015 Nov 25.


Using the Coriell Personalized Medicine Collaborative Data to conduct a genome-wide association study of sleep duration.

Scheinfeldt LB, Gharani N, Kasper RS, Schmidlen TJ, Gordon ES, Jarvis JP, Delaney S, Kronenthal CJ, Gerry NP, Christman MF.

Am J Med Genet B Neuropsychiatr Genet. 2015 Dec;168(8):697-705. doi: 10.1002/ajmg.b.32362. Epub 2015 Sep 3.


Genetic Knowledge Among Participants in the Coriell Personalized Medicine Collaborative.

Schmidlen TJ, Scheinfeldt L, Zhaoyang R, Kasper R, Sweet K, Gordon ES, Keller M, Stack C, Gharani N, Daly MB, Jarvis J, Christman MF.

J Genet Couns. 2016 Apr;25(2):385-94. doi: 10.1007/s10897-015-9883-z. Epub 2015 Aug 27.


Genetic testing of children for predisposition to mood disorders: anticipating the clinical issues.

Erickson JA, Kuzmich L, Ormond KE, Gordon E, Christman MF, Cho MK, Levinson DF.

J Genet Couns. 2014 Aug;23(4):566-77. doi: 10.1007/s10897-014-9710-y. Epub 2014 Mar 22.


Personalized genomic results: analysis of informational needs.

Schmidlen TJ, Wawak L, Kasper R, García-España JF, Christman MF, Gordon ES.

J Genet Couns. 2014 Aug;23(4):578-87. doi: 10.1007/s10897-014-9693-8. Epub 2014 Feb 3.


A randomized trial of the clinical utility of genetic testing for obesity: design and implementation considerations.

Wang C, Gordon ES, Stack CB, Liu CT, Norkunas T, Wawak L, Christman MF, Green RC, Bowen DJ.

Clin Trials. 2014 Feb;11(1):102-13. doi: 10.1177/1740774513508029. Epub 2013 Nov 11.


The Coriell personalized medicine collaborative pharmacogenomics appraisal, evidence scoring and interpretation system.

Gharani N, Keller MA, Stack CB, Hodges LM, Schmidlen TJ, Lynch DE, Gordon ES, Christman MF.

Genome Med. 2013 Oct 18;5(10):93. doi: 10.1186/gm499. eCollection 2013.


Multiple loci associated with renal function in African Americans.

Shriner D, Herbert A, Doumatey AP, Zhou J, Huang H, Erdos MR, Chen G, Gerry NP, Christman MF, Adeyemo A, Rotimi CN.

PLoS One. 2012;7(9):e45112. doi: 10.1371/journal.pone.0045112. Epub 2012 Sep 13.


Transferability and fine mapping of genome-wide associated loci for lipids in African Americans.

Adeyemo A, Bentley AR, Meilleur KG, Doumatey AP, Chen G, Zhou J, Shriner D, Huang H, Herbert A, Gerry NP, Christman MF, Rotimi CN.

BMC Med Genet. 2012 Sep 21;13:88. doi: 10.1186/1471-2350-13-88.


C-reactive protein (CRP) promoter polymorphisms influence circulating CRP levels in a genome-wide association study of African Americans.

Doumatey AP, Chen G, Tekola Ayele F, Zhou J, Erdos M, Shriner D, Huang H, Adeleye J, Balogun W, Fasanmade O, Johnson T, Oli J, Okafor G, Amoah A, Eghan BA, Agyenim-Boateng K, Acheampong J, Adebamowo C, Gerry NP, Christman MF, Adeyemo A, Rotimi CN.

Hum Mol Genet. 2012 Jul 1;21(13):3063-72. doi: 10.1093/hmg/dds133. Epub 2012 Apr 5.


Managing incidental findings and research results in genomic research involving biobanks and archived data sets.

Wolf SM, Crock BN, Van Ness B, Lawrenz F, Kahn JP, Beskow LM, Cho MK, Christman MF, Green RC, Hall R, Illes J, Keane M, Knoppers BM, Koenig BA, Kohane IS, Leroy B, Maschke KJ, McGeveran W, Ossorio P, Parker LS, Petersen GM, Richardson HS, Scott JA, Terry SF, Wilfond BS, Wolf WA.

Genet Med. 2012 Apr;14(4):361-84. doi: 10.1038/gim.2012.23.


Broadening research consent in the era of genome-informed medicine.

Kronenthal C, Delaney SK, Christman MF.

Genet Med. 2012 Apr;14(4):432-6. doi: 10.1038/gim.2011.76. Epub 2012 Mar 15.


UGT1A1 is a major locus influencing bilirubin levels in African Americans.

Chen G, Ramos E, Adeyemo A, Shriner D, Zhou J, Doumatey AP, Huang H, Erdos MR, Gerry NP, Herbert A, Bentley AR, Xu H, Charles BA, Christman MF, Rotimi CN.

Eur J Hum Genet. 2012 Apr;20(4):463-8. doi: 10.1038/ejhg.2011.206. Epub 2011 Nov 16.


Motivations and perceptions of early adopters of personalized genomics: perspectives from research participants.

Gollust SE, Gordon ES, Zayac C, Griffin G, Christman MF, Pyeritz RE, Wawak L, Bernhardt BA.

Public Health Genomics. 2012;15(1):22-30. doi: 10.1159/000327296. Epub 2011 Jun 3.


A genome-wide association study of serum uric acid in African Americans.

Charles BA, Shriner D, Doumatey A, Chen G, Zhou J, Huang H, Herbert A, Gerry NP, Christman MF, Adeyemo A, Rotimi CN.

BMC Med Genomics. 2011 Feb 4;4:17. doi: 10.1186/1755-8794-4-17.


Genetic risk estimation in the Coriell Personalized Medicine Collaborative.

Stack CB, Gharani N, Gordon ES, Schmidlen T, Christman MF, Keller MA.

Genet Med. 2011 Feb;13(2):131-9. doi: 10.1097/GIM.0b013e318201164c.


Replication of genome-wide association studies (GWAS) loci for fasting plasma glucose in African-Americans.

Ramos E, Chen G, Shriner D, Doumatey A, Gerry NP, Herbert A, Huang H, Zhou J, Christman MF, Adeyemo A, Rotimi C.

Diabetologia. 2011 Apr;54(4):783-8. doi: 10.1007/s00125-010-2002-7. Epub 2010 Dec 25.


Development of admixture mapping panels for African Americans from commercial high-density SNP arrays.

Chen G, Shriner D, Zhou J, Doumatey A, Huang H, Gerry NP, Herbert A, Christman MF, Chen Y, Dunston GM, Faruque MU, Rotimi CN, Adeyemo A.

BMC Genomics. 2010 Jul 5;11:417. doi: 10.1186/1471-2164-11-417.


Coriell Personalized Medicine Collaborative®: a prospective study of the utility of personalized medicine.

Keller MA, Gordon ES, Stack CB, Gharani N, Sill CJ, Schmidlen TJ, Joseph M, Pallies J, Gerry NP, Christman MF.

Per Med. 2010 May;7(3):301-317. doi: 10.2217/pme.10.13.


Transferability and fine-mapping of genome-wide associated loci for adult height across human populations.

Shriner D, Adeyemo A, Gerry NP, Herbert A, Chen G, Doumatey A, Huang H, Zhou J, Christman MF, Rotimi CN.

PLoS One. 2009 Dec 22;4(12):e8398. doi: 10.1371/journal.pone.0008398.


The signatures of autozygosity among patients with colorectal cancer.

Bacolod MD, Schemmann GS, Wang S, Shattock R, Giardina SF, Zeng Z, Shia J, Stengel RF, Gerry N, Hoh J, Kirchhoff T, Gold B, Christman MF, Offit K, Gerald WL, Notterman DA, Ott J, Paty PB, Barany F.

Cancer Res. 2008 Apr 15;68(8):2610-21. doi: 10.1158/0008-5472.CAN-07-5250. Epub 2008 Mar 28.


Open-access database of candidate associations from a genome-wide SNP scan of the Framingham Heart Study.

Herbert A, Lenburg ME, Ulrich D, Gerry NP, Schlauch K, Christman MF.

Nat Genet. 2007 Feb;39(2):135-6. No abstract available.


A common genetic variant is associated with adult and childhood obesity.

Herbert A, Gerry NP, McQueen MB, Heid IM, Pfeufer A, Illig T, Wichmann HE, Meitinger T, Hunter D, Hu FB, Colditz G, Hinney A, Hebebrand J, Koberwitz K, Zhu X, Cooper R, Ardlie K, Lyon H, Hirschhorn JN, Laird NM, Lenburg ME, Lange C, Christman MF.

Science. 2006 Apr 14;312(5771):279-83.


Pharmacogenomic identification of targets for adjuvant therapy with the topoisomerase poison camptothecin.

Carson JP, Zhang N, Frampton GM, Gerry NP, Lenburg ME, Christman MF.

Cancer Res. 2004 Mar 15;64(6):2096-104.


Previously unidentified changes in renal cell carcinoma gene expression identified by parametric analysis of microarray data.

Lenburg ME, Liou LS, Gerry NP, Frampton GM, Cohen HT, Christman MF.

BMC Cancer. 2003 Nov 27;3:31.


Acetylation of histone H4 by Esa1 is required for DNA double-strand break repair.

Bird AW, Yu DY, Pray-Grant MG, Qiu Q, Harmon KE, Megee PC, Grant PA, Smith MM, Christman MF.

Nature. 2002 Sep 26;419(6905):411-5.


Replication-related activities establish cohesion between sister chromatids.

Wang Z, Christman MF.

Cell Biochem Biophys. 2001;35(3):289-301. Review.


Structure/function analysis of the Saccharomyces cerevisiae Trf4/Pol sigma DNA polymerase.

Wang Z, Castaño IB, Adams C, Vu C, Fitzhugh D, Christman MF.

Genetics. 2002 Feb;160(2):381-91.


Eukaryotic DNA polymerases: proposal for a revised nomenclature.

Burgers PM, Koonin EV, Bruford E, Blanco L, Burtis KC, Christman MF, Copeland WC, Friedberg EC, Hanaoka F, Hinkle DC, Lawrence CW, Nakanishi M, Ohmori H, Prakash L, Prakash S, Reynaud CA, Sugino A, Todo T, Wang Z, Weill JC, Woodgate R.

J Biol Chem. 2001 Nov 23;276(47):43487-90. Epub 2001 Sep 28. Review. No abstract available.


Separase anxiety: dissolving the sister bond and more.

Pellman D, Christman MF.

Nat Cell Biol. 2001 Sep;3(9):E207-9. Review.


Evidence that replication fork components catalyze establishment of cohesion between sister chromatids.

Carson DR, Christman MF.

Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8270-5. Review.


Pol kappa: A DNA polymerase required for sister chromatid cohesion.

Wang Z, Castaño IB, De Las Peñas A, Adams C, Christman MF.

Science. 2000 Aug 4;289(5480):774-9.


The topoisomerase-related function gene TRF4 affects cellular sensitivity to the antitumor agent camptothecin.

Walowsky C, Fitzhugh DJ, Castaño IB, Ju JY, Levin NA, Christman MF.

J Biol Chem. 1999 Mar 12;274(11):7302-8.


Mitotic chromosome condensation in the rDNA requires TRF4 and DNA topoisomerase I in Saccharomyces cerevisiae.

Castaño IB, Brzoska PM, Sadoff BU, Chen H, Christman MF.

Genes Dev. 1996 Oct 15;10(20):2564-76.


Cloning, mapping, and in vivo localization of a human member of the PKCI-1 protein family (PRKCNH1).

Brzoska PM, Chen H, Levin NA, Kuo WL, Collins C, Fu KK, Gray JW, Christman MF.

Genomics. 1996 Aug 15;36(1):151-6.


A novel family of TRF (DNA topoisomerase I-related function) genes required for proper nuclear segregation.

Castaño IB, Heath-Pagliuso S, Sadoff BU, Fitzhugh DJ, Christman MF.

Nucleic Acids Res. 1996 Jun 15;24(12):2404-10.


Isolation of mutants of Saccharomyces cerevisiae requiring DNA topoisomerase I.

Sadoff BU, Heath-Pagliuso S, Castaño IB, Zhu Y, Kieff FS, Christman MF.

Genetics. 1995 Oct;141(2):465-79.


The product of the ataxia-telangiectasia group D complementing gene, ATDC, interacts with a protein kinase C substrate and inhibitor.

Brzoska PM, Chen H, Zhu Y, Levin NA, Disatnik MH, Mochly-Rosen D, Murnane JP, Christman MF.

Proc Natl Acad Sci U S A. 1995 Aug 15;92(17):7824-8.


Frequent novel DNA copy number increase in squamous cell head and neck tumors.

Brzoska PM, Levin NA, Fu KK, Kaplan MJ, Singer MI, Gray JW, Christman MF.

Cancer Res. 1995 Jul 15;55(14):3055-9.


Identification of novel regions of altered DNA copy number in small cell lung tumors.

Levin NA, Brzoska PM, Warnock ML, Gray JW, Christman MF.

Genes Chromosomes Cancer. 1995 Jul;13(3):175-85.


Neurofibromatosis type 2 (NF2) gene is somatically mutated in mesothelioma but not in lung cancer.

Sekido Y, Pass HI, Bader S, Mew DJ, Christman MF, Gazdar AF, Minna JD.

Cancer Res. 1995 Mar 15;55(6):1227-31.

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