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Items: 1 to 20 of 70

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1.

Synthetic biology strategies toward heterologous phytochemical production.

Kotopka BJ, Li Y, Smolke CD.

Nat Prod Rep. 2018 Sep 19;35(9):902-920. doi: 10.1039/c8np00028j. Review.

PMID:
29897091
2.

Complete biosynthesis of noscapine and halogenated alkaloids in yeast.

Li Y, Li S, Thodey K, Trenchard I, Cravens A, Smolke CD.

Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):E3922-E3931. doi: 10.1073/pnas.1721469115. Epub 2018 Apr 2.

PMID:
29610307
3.

Strategies for microbial synthesis of high-value phytochemicals.

Li S, Li Y, Smolke CD.

Nat Chem. 2018 Apr;10(4):395-404. doi: 10.1038/s41557-018-0013-z. Epub 2018 Mar 22. Review.

PMID:
29568052
4.

Regulation of T cell proliferation with drug-responsive microRNA switches.

Wong RS, Chen YY, Smolke CD.

Nucleic Acids Res. 2018 Feb 16;46(3):1541-1552. doi: 10.1093/nar/gkx1228.

5.

Mammalian synthetic biology for studying the cell.

Mathur M, Xiang JS, Smolke CD.

J Cell Biol. 2017 Jan 2;216(1):73-82. doi: 10.1083/jcb.201611002. Epub 2016 Dec 8. Review.

6.

Design and Construction of Generalizable RNA-Protein Hybrid Controllers by Level-Matched Genetic Signal Amplification.

Wang YH, McKeague M, Hsu TM, Smolke CD.

Cell Syst. 2016 Dec 21;3(6):549-562.e7. doi: 10.1016/j.cels.2016.10.008. Epub 2016 Nov 10.

7.

Engineering a microbial platform for de novo biosynthesis of diverse methylxanthines.

McKeague M, Wang YH, Cravens A, Win MN, Smolke CD.

Metab Eng. 2016 Nov;38:191-203. doi: 10.1016/j.ymben.2016.08.003. Epub 2016 Aug 9.

8.

Engineering biosynthesis of the anticancer alkaloid noscapine in yeast.

Li Y, Smolke CD.

Nat Commun. 2016 Jul 5;7:12137. doi: 10.1038/ncomms12137.

9.

Opportunities in the design and application of RNA for gene expression control.

McKeague M, Wong RS, Smolke CD.

Nucleic Acids Res. 2016 Apr 20;44(7):2987-99. doi: 10.1093/nar/gkw151. Epub 2016 Mar 11. Review.

10.

Engineering dynamic cell cycle control with synthetic small molecule-responsive RNA devices.

Wei KY, Smolke CD.

J Biol Eng. 2015 Nov 20;9:21. doi: 10.1186/s13036-015-0019-7. eCollection 2015.

11.

Optimization of yeast-based production of medicinal protoberberine alkaloids.

Galanie S, Smolke CD.

Microb Cell Fact. 2015 Sep 16;14:144. doi: 10.1186/s12934-015-0332-3.

12.

In Vitro Screening and in Silico Modeling of RNA-Based Gene Expression Control.

McKeague M, Wang YH, Smolke CD.

ACS Chem Biol. 2015 Nov 20;10(11):2463-2467. doi: 10.1021/acschembio.5b00518. Epub 2015 Sep 22.

13.

Complete biosynthesis of opioids in yeast.

Galanie S, Thodey K, Trenchard IJ, Filsinger Interrante M, Smolke CD.

Science. 2015 Sep 4;349(6252):1095-100. doi: 10.1126/science.aac9373. Epub 2015 Aug 13.

14.

High-throughput cellular RNA device engineering.

Townshend B, Kennedy AB, Xiang JS, Smolke CD.

Nat Methods. 2015 Oct;12(10):989-94. doi: 10.1038/nmeth.3486. Epub 2015 Aug 10.

15.

De novo production of the key branch point benzylisoquinoline alkaloid reticuline in yeast.

Trenchard IJ, Siddiqui MS, Thodey K, Smolke CD.

Metab Eng. 2015 Sep;31:74-83. doi: 10.1016/j.ymben.2015.06.010. Epub 2015 Jul 10.

16.

Control of alphavirus-based gene expression using engineered riboswitches.

Bell CL, Yu D, Smolke CD, Geall AJ, Beard CW, Mason PW.

Virology. 2015 Sep;483:302-11. doi: 10.1016/j.virol.2015.04.023. Epub 2015 May 23.

17.

Engineering strategies for the fermentative production of plant alkaloids in yeast.

Trenchard IJ, Smolke CD.

Metab Eng. 2015 Jul;30:96-104. doi: 10.1016/j.ymben.2015.05.001. Epub 2015 May 14.

18.

Synthetic feedback control using an RNAi-based gene-regulatory device.

Bloom RJ, Winkler SM, Smolke CD.

J Biol Eng. 2015 Apr 14;9:5. doi: 10.1186/s13036-015-0002-3. eCollection 2015.

19.

Facile characterization of aptamer kinetic and equilibrium binding properties using surface plasmon resonance.

Chang AL, McKeague M, Smolke CD.

Methods Enzymol. 2014;549:451-66. doi: 10.1016/B978-0-12-801122-5.00019-2.

20.

Protein-responsive ribozyme switches in eukaryotic cells.

Kennedy AB, Vowles JV, d'Espaux L, Smolke CD.

Nucleic Acids Res. 2014 Oct 29;42(19):12306-21. doi: 10.1093/nar/gku875. Epub 2014 Oct 1.

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