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Items: 1 to 50 of 311

1.

Plant Polyphenols Inhibit Functional Amyloid and Biofilm Formation in Pseudomonas Strains by Directing Monomers to Off-Pathway Oligomers.

Najarzadeh Z, Mohammad-Beigi H, Nedergaard Pedersen J, Christiansen G, Sønderby TV, Shojaosadati SA, Morshedi D, Strømgaard K, Meisl G, Sutherland D, Skov Pedersen J, Otzen DE.

Biomolecules. 2019 Oct 26;9(11). pii: E659. doi: 10.3390/biom9110659.

PMID:
31717821
2.

Complement mediated Klebsiella pneumoniae capsule changes.

Jensen TS, Opstrup KV, Christiansen G, Rasmussen PV, Thomsen ME, Justesen DL, Schønheyder HC, Lausen M, Birkelund S.

Microbes Infect. 2019 Aug 29. pii: S1286-4579(19)30086-3. doi: 10.1016/j.micinf.2019.08.003. [Epub ahead of print]

PMID:
31473336
3.

Reducing the Amyloidogenicity of Functional Amyloid Protein FapC Increases Its Ability To Inhibit α-Synuclein Fibrillation.

Christensen LFB, Jensen KF, Nielsen J, Vad BS, Christiansen G, Otzen DE.

ACS Omega. 2019 Feb 22;4(2):4029-4039. doi: 10.1021/acsomega.8b03590. eCollection 2019 Feb 28.

4.

Bacterial amphiphiles as amyloid inducers: Effect of Rhamnolipid and Lipopolysaccharide on FapC fibrillation.

Najarzadeh Z, Pedersen JN, Christiansen G, Shojaosadati SA, Pedersen JS, Otzen DE.

Biochim Biophys Acta Proteins Proteom. 2019 Nov;1867(11):140263. doi: 10.1016/j.bbapap.2019.140263. Epub 2019 Aug 14.

PMID:
31421227
5.

The repeated 36 amino acid motif of Chlamydia trachomatis Hc2 protein binds to the major groove of DNA.

Gonçalves OSL, Christiansen G, Holm A, Herrmann B, Klintstedt M, Petersen SB, Birkelund S.

Res Microbiol. 2019 Sep - Oct;170(6-7):256-262. doi: 10.1016/j.resmic.2019.08.002. Epub 2019 Aug 13.

PMID:
31419583
6.

Antibiotic hypersensitivity in MRSA induced by special protein aggregates.

Tafvizizavareh S, Shariati P, Sharifirad A, Maleki B, Aliakbari F, Christiansen G, Morshedi D.

Int J Biol Macromol. 2019 Sep 15;137:528-536. doi: 10.1016/j.ijbiomac.2019.07.001. Epub 2019 Jul 2.

PMID:
31271798
7.

The serine protease HtrA1 cleaves misfolded transforming growth factor β-induced protein (TGFBIp) and induces amyloid formation.

Poulsen ET, Nielsen NS, Scavenius C, Mogensen EH, Risør MW, Runager K, Lukassen MV, Rasmussen CB, Christiansen G, Richner M, Vorum H, Enghild JJ.

J Biol Chem. 2019 Aug 2;294(31):11817-11828. doi: 10.1074/jbc.RA119.009050. Epub 2019 Jun 13.

8.

A tumorsphere model of glioblastoma multiforme with intratumoral heterogeneity for quantitative analysis of cellular migration and drug response.

Gudbergsson JM, Kostrikov S, Johnsen KB, Fliedner FP, Stolberg CB, Humle N, Hansen AE, Kristensen BW, Christiansen G, Kjær A, Andresen TL, Duroux M.

Exp Cell Res. 2019 Jun 1;379(1):73-82. doi: 10.1016/j.yexcr.2019.03.031. Epub 2019 Mar 25.

PMID:
30922921
9.

Two conformationally distinct α-synuclein oligomers share common epitopes and the ability to impair long-term potentiation.

van Diggelen F, Hrle D, Apetri M, Christiansen G, Rammes G, Tepper A, Otzen DE.

PLoS One. 2019 Mar 22;14(3):e0213663. doi: 10.1371/journal.pone.0213663. eCollection 2019.

10.

A Possible Connection Between Plant Longevity and the Absence of Protein Fibrillation: Basis for Identifying Aggregation Inhibitors in Plants.

Mohammad-Beigi H, Kjaer L, Eskandari H, Aliakbari F, Christiansen G, Ruvo G, Ward JL, Otzen DE.

Front Plant Sci. 2019 Feb 13;10:148. doi: 10.3389/fpls.2019.00148. eCollection 2019.

11.

Mechanistic Understanding of the Interactions between Nano-Objects with Different Surface Properties and α-Synuclein.

Mohammad-Beigi H, Hosseini A, Adeli M, Ejtehadi MR, Christiansen G, Sahin C, Tu Z, Tavakol M, Dilmaghani-Marand A, Nabipour I, Farzadfar F, Otzen DE, Mahmoudi M, Hajipour MJ.

ACS Nano. 2019 Mar 26;13(3):3243-3256. doi: 10.1021/acsnano.8b08983. Epub 2019 Feb 27.

PMID:
30810027
12.

Oleuropein derivatives from olive fruit extracts reduce α-synuclein fibrillation and oligomer toxicity.

Mohammad-Beigi H, Aliakbari F, Sahin C, Lomax C, Tawfike A, Schafer NP, Amiri-Nowdijeh A, Eskandari H, Møller IM, Hosseini-Mazinani M, Christiansen G, Ward JL, Morshedi D, Otzen DE.

J Biol Chem. 2019 Mar 15;294(11):4215-4232. doi: 10.1074/jbc.RA118.005723. Epub 2019 Jan 17.

PMID:
30655291
13.

Extracellular vesicle-associated procoagulant phospholipid and tissue factor activity in multiple myeloma.

Nielsen T, Kristensen SR, Gregersen H, Teodorescu EM, Christiansen G, Pedersen S.

PLoS One. 2019 Jan 14;14(1):e0210835. doi: 10.1371/journal.pone.0210835. eCollection 2019.

14.

Imperfect repeats in the functional amyloid protein FapC reduce the tendency to fragment during fibrillation.

Rasmussen CB, Christiansen G, Vad BS, Lynggaard C, Enghild JJ, Andreasen M, Otzen D.

Protein Sci. 2019 Mar;28(3):633-642. doi: 10.1002/pro.3566. Epub 2019 Jan 12.

PMID:
30592554
15.

Immunobiology of monocytes and macrophages during Chlamydia trachomatis infection.

Lausen M, Christiansen G, Bouet Guldbæk Poulsen T, Birkelund S.

Microbes Infect. 2019 Mar;21(2):73-84. doi: 10.1016/j.micinf.2018.10.007. Epub 2018 Dec 8. Review.

PMID:
30528899
16.

The Sheaths of Methanospirillum Are Made of a New Type of Amyloid Protein.

Christensen LFB, Hansen LM, Finster K, Christiansen G, Nielsen PH, Otzen DE, Dueholm MS.

Front Microbiol. 2018 Nov 13;9:2729. doi: 10.3389/fmicb.2018.02729. eCollection 2018.

17.

Lysophospholipids induce fibrillation of the repeat domain of Pmel17 through intermediate core-shell structures.

Pedersen JN, Jiang Z, Christiansen G, Lee JC, Pedersen JS, Otzen DE.

Biochim Biophys Acta Proteins Proteom. 2019 May;1867(5):519-528. doi: 10.1016/j.bbapap.2018.11.007. Epub 2018 Nov 22.

PMID:
30471451
18.

Proteomic analysis of lipopolysaccharide activated human monocytes.

Lausen M, Poulsen TBG, Christiansen G, Kastaniegaard K, Stensballe A, Birkelund S.

Mol Immunol. 2018 Nov;103:257-269. doi: 10.1016/j.molimm.2018.09.016. Epub 2018 Oct 13.

PMID:
30326359
19.

Potent α-Synuclein Aggregation Inhibitors, Identified by High-Throughput Screening, Mainly Target the Monomeric State.

Kurnik M, Sahin C, Andersen CB, Lorenzen N, Giehm L, Mohammad-Beigi H, Jessen CM, Pedersen JS, Christiansen G, Petersen SV, Staal R, Krishnamurthy G, Pitts K, Reinhart PH, Mulder FAA, Mente S, Hirst WD, Otzen DE.

Cell Chem Biol. 2018 Nov 15;25(11):1389-1402.e9. doi: 10.1016/j.chembiol.2018.08.005. Epub 2018 Sep 6.

PMID:
30197194
20.

α-Synucleins from Animal Species Show Low Fibrillation Propensities and Weak Oligomer Membrane Disruption.

Sahin C, Kjær L, Christensen MS, N Pedersen J, Christiansen G, Pérez AW, Møller IM, Enghild JJ, Pedersen JS, Larsen K, Otzen DE.

Biochemistry. 2018 Aug 28;57(34):5145-5158. doi: 10.1021/acs.biochem.8b00627. Epub 2018 Aug 15.

PMID:
30067901
21.

Avulsion fracture of the tibial eminence in an adult with a unique mechanism of injury.

Patterson SP, Christiansen GB, Daffner RH.

Radiol Case Rep. 2018 Jun 26;13(4):843-847. doi: 10.1016/j.radcr.2018.05.015. eCollection 2018 Aug.

22.

Protein Engineering Reveals Mechanisms of Functional Amyloid Formation in Pseudomonas aeruginosa Biofilms.

Bleem A, Christiansen G, Madsen DJ, Maric H, Strømgaard K, Bryers JD, Daggett V, Meyer RL, Otzen DE.

J Mol Biol. 2018 Oct 12;430(20):3751-3763. doi: 10.1016/j.jmb.2018.06.043. Epub 2018 Jun 30.

23.

Complement C3 opsonization of Chlamydia trachomatis facilitates uptake in human monocytes.

Lausen M, Christiansen G, Karred N, Winther R, Poulsen TBG, Palarasah Y, Birkelund S.

Microbes Infect. 2018 Jun - Jul;20(6):328-336. doi: 10.1016/j.micinf.2018.04.004. Epub 2018 May 3.

PMID:
29729435
24.

The potential of zwitterionic nanoliposomes against neurotoxic alpha-synuclein aggregates in Parkinson's Disease.

Aliakbari F, Mohammad-Beigi H, Rezaei-Ghaleh N, Becker S, Dehghani Esmatabad F, Eslampanah Seyedi HA, Bardania H, Tayaranian Marvian A, Collingwood JF, Christiansen G, Zweckstetter M, Otzen DE, Morshedi D.

Nanoscale. 2018 May 17;10(19):9174-9185. doi: 10.1039/c8nr00632f.

PMID:
29725687
25.

Investigation of procoagulant activity in extracellular vesicles isolated by differential ultracentrifugation.

Nielsen T, Kristensen AF, Pedersen S, Christiansen G, Kristensen SR.

J Extracell Vesicles. 2018 Mar 26;7(1):1454777. doi: 10.1080/20013078.2018.1454777. eCollection 2018.

26.

Pseudomonas aeruginosa rhamnolipid induces fibrillation of human α-synuclein and modulates its effect on biofilm formation.

Andersen KK, Vad BS, Kjaer L, Tolker-Nielsen T, Christiansen G, Otzen DE.

FEBS Lett. 2018 May;592(9):1484-1496. doi: 10.1002/1873-3468.13038. Epub 2018 Apr 10.

27.

Single colony genetic analysis of epilithic stream algae of the genus Chamaesiphon spp.

Kurmayer R, Christiansen G, Holzinger A, Rott E.

Hydrobiologia. 2018 Apr;811(1):61-75. doi: 10.1007/s10750-017-3295-z. Epub 2017 Aug 21.

28.

Corneal Dystrophy Mutations Drive Pathogenesis by Targeting TGFBIp Stability and Solubility in a Latent Amyloid-forming Domain.

Stenvang M, Schafer NP, Malmos KG, Pérez AW, Niembro O, Sormanni P, Basaiawmoit RV, Christiansen G, Andreasen M, Otzen DE.

J Mol Biol. 2018 Apr 13;430(8):1116-1140. doi: 10.1016/j.jmb.2018.03.001. Epub 2018 Mar 7.

PMID:
29524512
29.

Formulation and anti-neurotoxic activity of baicalein-incorporating neutral nanoliposome.

Aliakbari F, Shabani AA, Bardania H, Mohammad-Beigi H, Tayaranian Marvian A, Dehghani Esmatabad F, Vafaei AA, Shojaosadati SA, Saboury AA, Christiansen G, Otzen DE, Morshedi D.

Colloids Surf B Biointerfaces. 2018 Jan 1;161:578-587. doi: 10.1016/j.colsurfb.2017.11.023. Epub 2017 Nov 11.

PMID:
29149763
30.

Management of an Entrapped Patient with a Field Amputation.

Bunyasaranand JC, Espino E, Rummings KA, Christiansen GM.

J Emerg Med. 2018 Jan;54(1):90-95. doi: 10.1016/j.jemermed.2017.08.097. Epub 2017 Nov 6.

PMID:
29102097
31.

Proteomics dataset: The colon mucosa from inflammatory bowel disease patients, gastrointestinal asymptomic rheumatoid arthritis patients, and controls.

Bennike TB, Carlsen TG, Ellingsen T, Bonderup OK, Glerup H, Bøgsted M, Christiansen G, Birkelund S, Andersen V, Stensballe A.

Data Brief. 2017 Oct 6;15:511-516. doi: 10.1016/j.dib.2017.09.059. eCollection 2017 Dec.

32.

How glycosaminoglycans promote fibrillation of salmon calcitonin.

Malmos KG, Bjerring M, Jessen CM, Nielsen EHT, Poulsen ET, Christiansen G, Vosegaard T, Skrydstrup T, Enghild JJ, Pedersen JS, Otzen DE.

J Biol Chem. 2017 Sep 22;292(38):15992. doi: 10.1074/jbc.A116.715466. No abstract available.

33.

The Changing Face of Aging: Highly Sulfated Glycosaminoglycans Induce Amyloid Formation in a Lattice Corneal Dystrophy Model Protein.

Malmos KG, Stenvang M, Sahin C, Christiansen G, Otzen DE.

J Mol Biol. 2017 Sep 1;429(18):2755-2764. doi: 10.1016/j.jmb.2017.07.014. Epub 2017 Jul 21.

PMID:
28739480
34.

Evolution of Anabaenopeptin Peptide Structural Variability in the Cyanobacterium Planktothrix.

Entfellner E, Frei M, Christiansen G, Deng L, Blom J, Kurmayer R.

Front Microbiol. 2017 Feb 16;8:219. doi: 10.3389/fmicb.2017.00219. eCollection 2017.

35.

A NATIONAL UPSET The Remedy Starts Here.

Christiansen G.

Iowa Med. 2017 Winter;107(1):22-23.

PMID:
30230286
36.

The sorting receptor SorCS3 is a stronger regulator of glutamate receptor functions compared to GABAergic mechanisms in the hippocampus.

Christiansen GB, Andersen KH, Riis S, Nykjaer A, Bolcho U, Jensen MS, Holm MM.

Hippocampus. 2017 Mar;27(3):235-248. doi: 10.1002/hipo.22689. Epub 2017 Feb 3.

PMID:
27935149
37.

Antibodies against the C-terminus of α-synuclein modulate its fibrillation.

Sahin C, Lorenzen N, Lemminger L, Christiansen G, Møller IM, Vesterager LB, Pedersen LØ, Fog K, Kallunki P, Otzen DE.

Biophys Chem. 2017 Jan;220:34-41. doi: 10.1016/j.bpc.2016.11.002. Epub 2016 Nov 10.

PMID:
27863716
38.

Epigallocatechin Gallate Remodels Overexpressed Functional Amyloids in Pseudomonas aeruginosa and Increases Biofilm Susceptibility to Antibiotic Treatment.

Stenvang M, Dueholm MS, Vad BS, Seviour T, Zeng G, Geifman-Shochat S, Søndergaard MT, Christiansen G, Meyer RL, Kjelleberg S, Nielsen PH, Otzen DE.

J Biol Chem. 2016 Dec 16;291(51):26540-26553. Epub 2016 Oct 26.

39.

A standardized method to determine the concentration of extracellular vesicles using tunable resistive pulse sensing.

Vogel R, Coumans FA, Maltesen RG, Böing AN, Bonnington KE, Broekman ML, Broom MF, Buzás EI, Christiansen G, Hajji N, Kristensen SR, Kuehn MJ, Lund SM, Maas SL, Nieuwland R, Osteikoetxea X, Schnoor R, Scicluna BJ, Shambrook M, de Vrij J, Mann SI, Hill AF, Pedersen S.

J Extracell Vesicles. 2016 Sep 27;5:31242. doi: 10.3402/jev.v5.31242. eCollection 2016.

40.

Proteome Analysis of Rheumatoid Arthritis Gut Mucosa.

Bennike TB, Ellingsen T, Glerup H, Bonderup OK, Carlsen TG, Meyer MK, Bøgsted M, Christiansen G, Birkelund S, Andersen V, Stensballe A.

J Proteome Res. 2017 Jan 6;16(1):346-354. doi: 10.1021/acs.jproteome.6b00598. Epub 2016 Sep 27.

PMID:
27627584
41.

Compartment syndrome of the deltoid: a case report of a common presentation in a rare location.

Harrison A, Sumner M, Sobecki J, Christiansen G.

Hosp Pract (1995). 2016 Oct;44(4):224-226. Epub 2016 Aug 16.

PMID:
27447677
42.

Reclassification of Alteromonas fuliginea (Romanenko et al. 1995) as Pseudoalteromonas fuliginea comb. nov. and an emended description.

Machado H, Vynne NG, Christiansen G, Gram L.

Int J Syst Evol Microbiol. 2016 Sep;66(9):3737-3742. doi: 10.1099/ijsem.0.001259. Epub 2016 Jul 5.

PMID:
27380907
43.

A Complex Dance: The Importance of Glycosaminoglycans and Zinc in the Aggregation of Human Prolactin.

Christensen LF, Malmos KG, Christiansen G, Otzen DE.

Biochemistry. 2016 Jul 5;55(26):3674-84. doi: 10.1021/acs.biochem.6b00153. Epub 2016 Jun 22.

PMID:
27305175
44.

How Glycosaminoglycans Promote Fibrillation of Salmon Calcitonin.

Malmos KG, Bjerring M, Jessen CM, Nielsen EH, Poulsen ET, Christiansen G, Vosegaard T, Skrydstrup T, Enghild JJ, Pedersen JS, Otzen DE.

J Biol Chem. 2016 Aug 5;291(32):16849-62. doi: 10.1074/jbc.M116.715466. Epub 2016 Jun 8. Erratum in: J Biol Chem. 2017 Sep 22;292(38):15992.

45.

The transcriptional regulator GalR self-assembles to form highly regular tubular structures.

Agerschou ED, Christiansen G, Schafer NP, Madsen DJ, Brodersen DE, Semsey S, Otzen DE.

Sci Rep. 2016 Jun 9;6:27672. doi: 10.1038/srep27672.

46.

Epigallocatechin Gallate Remodels Fibrils of Lattice Corneal Dystrophy Protein, Facilitating Proteolytic Degradation and Preventing Formation of Membrane-Permeabilizing Species.

Stenvang M, Christiansen G, Otzen DE.

Biochemistry. 2016 Apr 26;55(16):2344-57. doi: 10.1021/acs.biochem.6b00063. Epub 2016 Apr 14.

PMID:
27042751
47.

Emergence of nontoxic mutants as revealed by single filament analysis in bloom-forming cyanobacteria of the genus Planktothrix.

Chen Q, Christiansen G, Deng L, Kurmayer R.

BMC Microbiol. 2016 Feb 25;16:23. doi: 10.1186/s12866-016-0639-1.

48.

Evaluation of electroporation-induced adverse effects on adipose-derived stem cell exosomes.

Johnsen KB, Gudbergsson JM, Skov MN, Christiansen G, Gurevich L, Moos T, Duroux M.

Cytotechnology. 2016 Oct;68(5):2125-38. doi: 10.1007/s10616-016-9952-7. Epub 2016 Feb 8.

49.

Strong interactions with polyethylenimine-coated human serum albumin nanoparticles (PEI-HSA NPs) alter α-synuclein conformation and aggregation kinetics.

Mohammad-Beigi H, Shojaosadati SA, Marvian AT, Pedersen JN, Klausen LH, Christiansen G, Pedersen JS, Dong M, Morshedi D, Otzen DE.

Nanoscale. 2015 Dec 14;7(46):19627-40. doi: 10.1039/c5nr05663b.

PMID:
26549058
50.

Functional bacterial amyloid increases Pseudomonas biofilm hydrophobicity and stiffness.

Zeng G, Vad BS, Dueholm MS, Christiansen G, Nilsson M, Tolker-Nielsen T, Nielsen PH, Meyer RL, Otzen DE.

Front Microbiol. 2015 Oct 7;6:1099. doi: 10.3389/fmicb.2015.01099. eCollection 2015.

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