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Items: 1 to 50 of 391

1.

High-throughput T cell receptor sequencing identifies clonally expanded CD8+ T cell populations in alopecia areata.

de Jong A, Jabbari A, Dai Z, Xing L, Lee D, Li MM, Duvic M, Hordinsky M, Norris DA, Price V, Mackay-Wiggan J, Clynes R, Christiano AM.

JCI Insight. 2018 Oct 4;3(19). pii: 121949. doi: 10.1172/jci.insight.121949. [Epub ahead of print]

2.

Tofacitinib for the treatment of lichen planopilaris: A case series.

Yang CC, Khanna T, Sallee B, Christiano AM, Bordone LA.

Dermatol Ther. 2018 Sep 27:e12656. doi: 10.1111/dth.12656. [Epub ahead of print]

PMID:
30264512
3.

Cord Blood-Derived Stem Cells Suppress Fibrosis and May Prevent Malignant Progression in Recessive Dystrophic Epidermolysis Bullosa.

Liao Y, Ivanova L, Zhu H, Plumer T, Hamby C, Mehta B, Gevertz A, Christiano AM, McGrath JA, Cairo MS.

Stem Cells. 2018 Sep 24. doi: 10.1002/stem.2907. [Epub ahead of print]

PMID:
30247783
4.

Hair Follicle Dermal Cells Support Expansion of Murine and Human Embryonic and Induced Pluripotent Stem Cells and Promote Haematopoiesis in Mouse Cultures.

Liu J, Higgins CA, Whitehouse JC, Harris SJ, Crawford H, Christiano AM, Lako M, Hole N, Jahoda CAB.

Stem Cells Int. 2018 Aug 2;2018:8631432. doi: 10.1155/2018/8631432. eCollection 2018.

5.

JAK Inhibitors for Treatment of Alopecia Areata.

Wang EHC, Sallee BN, Tejeda CI, Christiano AM.

J Invest Dermatol. 2018 Sep;138(9):1911-1916. doi: 10.1016/j.jid.2018.05.027. Epub 2018 Jul 26. Review.

PMID:
30057345
6.

IKZF1 Enhances Immune Infiltrate Recruitment in Solid Tumors and Susceptibility to Immunotherapy.

Chen JC, Perez-Lorenzo R, Saenger YM, Drake CG, Christiano AM.

Cell Syst. 2018 Jul 25;7(1):92-103.e4. doi: 10.1016/j.cels.2018.05.020. Epub 2018 Jun 27.

PMID:
29960886
7.

Efficacy of Human Placental-Derived Stem Cells in Collagen VII Knockout (Recessive Dystrophic Epidermolysis Bullosa) Animal Model.

Liao Y, Ivanova L, Sivalenka R, Plumer T, Zhu H, Zhang X, Christiano AM, McGrath JA, Gurney JP, Cairo MS.

Stem Cells Transl Med. 2018 Jul;7(7):530-542. doi: 10.1002/sctm.17-0182. Epub 2018 May 10.

8.

STXBP4 regulates APC/C-mediated p63 turnover and drives squamous cell carcinogenesis.

Rokudai S, Li Y, Otaka Y, Fujieda M, Owens DM, Christiano AM, Nishiyama M, Prives C.

Proc Natl Acad Sci U S A. 2018 May 22;115(21):E4806-E4814. doi: 10.1073/pnas.1718546115. Epub 2018 May 7.

PMID:
29735662
9.

Production-scale fibronectin nanofibers promote wound closure and tissue repair in a dermal mouse model.

Chantre CO, Campbell PH, Golecki HM, Buganza AT, Capulli AK, Deravi LF, Dauth S, Sheehy SP, Paten JA, Gledhill K, Doucet YS, Abaci HE, Ahn S, Pope BD, Ruberti JW, Hoerstrup SP, Christiano AM, Parker KK.

Biomaterials. 2018 Jun;166:96-108. doi: 10.1016/j.biomaterials.2018.03.006. Epub 2018 Mar 5.

PMID:
29549768
10.

Alopecia areata is a medical disease.

Korta DZ, Christiano AM, Bergfeld W, Duvic M, Ellison A, Fu J, Harris JE, Hordinsky MK, King B, Kranz D, Mackay-Wiggan J, McMichael A, Norris DA, Price V, Shapiro J, Atanaskova Mesinkovska N.

J Am Acad Dermatol. 2018 Apr;78(4):832-834. doi: 10.1016/j.jaad.2017.09.011. No abstract available.

PMID:
29548423
11.

An Open-Label Pilot Study to Evaluate the Efficacy of Tofacitinib in Moderate to Severe Patch-Type Alopecia Areata, Totalis, and Universalis.

Jabbari A, Sansaricq F, Cerise J, Chen JC, Bitterman A, Ulerio G, Borbon J, Clynes R, Christiano AM, Mackay-Wiggan J.

J Invest Dermatol. 2018 Jul;138(7):1539-1545. doi: 10.1016/j.jid.2018.01.032. Epub 2018 Feb 13.

PMID:
29452121
12.

Cicatricial Alopecia Research Foundation meeting, May 2016: Progress towards the diagnosis, treatment and cure of primary cicatricial alopecias.

Sundberg JP, Hordinsky MK, Bergfeld W, Lenzy YM, McMichael AJ, Christiano AM, McGregor T, Stenn KS, Sivamani RK, Pratt CH, King LE Jr.

Exp Dermatol. 2018 Mar;27(3):302-310. doi: 10.1111/exd.13495.

PMID:
29341265
13.

Large-Scale Epitope Identification Screen and Its Potential Application to the Study of Alopecia Areata.

Lindestam Arlehamn CS, Paul S, Chun Wang EH, de Jong A, Christiano AM, Sette A.

J Investig Dermatol Symp Proc. 2018 Jan;19(1):S54-S56. doi: 10.1016/j.jisp.2017.10.001. No abstract available.

PMID:
29273108
14.

Building and Crossing the Translational Bridge: 2016 Alopecia Areata Research Summit Highlights.

Kranz D, Ellison A, Mesinkovska NA, Christiano AM, Hordinsky MK, Harris JE.

J Investig Dermatol Symp Proc. 2018 Jan;19(1):S3-S8. doi: 10.1016/j.jisp.2017.10.004.

PMID:
29273102
15.

Alopecia areata: An appraisal of new treatment approaches and overview of current therapies.

Strazzulla LC, Wang EHC, Avila L, Lo Sicco K, Brinster N, Christiano AM, Shapiro J.

J Am Acad Dermatol. 2018 Jan;78(1):15-24. doi: 10.1016/j.jaad.2017.04.1142. Review.

PMID:
29241773
16.

Alopecia areata: Disease characteristics, clinical evaluation, and new perspectives on pathogenesis.

Strazzulla LC, Wang EHC, Avila L, Lo Sicco K, Brinster N, Christiano AM, Shapiro J.

J Am Acad Dermatol. 2018 Jan;78(1):1-12. doi: 10.1016/j.jaad.2017.04.1141. Review.

PMID:
29241771
17.

Novel therapies for alopecia areata: The era of rational drug development.

Wang ECE, Dai Z, Christiano AM.

J Allergy Clin Immunol. 2018 Feb;141(2):499-504. doi: 10.1016/j.jaci.2017.10.028. Epub 2017 Dec 28.

PMID:
29155099
18.

Genome-Wide MicroRNA Analysis Implicates miR-30b/d in the Etiology of Alopecia Areata.

Tafazzoli A, Forstner AJ, Broadley D, Hofmann A, Redler S, Petukhova L, Giehl KA, Kruse R, Blaumeiser B, Böhm M, Bertolini M, Rossi A, Garcia Bartels N, Lutz G, Wolff H, Blume-Peytavi U, Soreq H, Christiano AM, Botchkareva NV, Nöthen MM, Betz RC.

J Invest Dermatol. 2018 Mar;138(3):549-556. doi: 10.1016/j.jid.2017.09.046. Epub 2017 Dec 6.

PMID:
29080678
19.

Large Scale Epitope Identification Screen and Its Potential Application to the Study of Alopecia Areata.

Lindestam Arlehamn CS, Paul S, Wang EHC, de Jong A, Christiano AM, Sette A.

J Invest Dermatol. 2017 Aug 29. pii: S0022-202X(17)32832-4. doi: 10.1016/j.jid.2017.08.018. [Epub ahead of print] No abstract available.

PMID:
28864075
20.

Proceedings of the Ninth World Congress for Hair Research (2015).

Bergfeld WF, Christiano AM, Hordinsky MK; Faculty of the Ninth World Congress of Hair Research.

J Investig Dermatol Symp Proc. 2017;18(1):S1-S28. doi: 10.1016/j.jisp.2017.03.001. Review. No abstract available.

21.

The Changing Landscape of Alopecia Areata: The Translational Landscape.

Wang ECE, Christiano AM.

Adv Ther. 2017 Jul;34(7):1586-1593. doi: 10.1007/s12325-017-0540-9. Epub 2017 Jun 23. Review.

22.

Alopecia areata.

Pratt CH, King LE Jr, Messenger AG, Christiano AM, Sundberg JP.

Nat Rev Dis Primers. 2017 Mar 16;3:17011. doi: 10.1038/nrdp.2017.11. Review.

23.

Identification of differentially expressed miRNAs in alopecia areata that target immune-regulatory pathways.

Wang EHC, DeStefano GM, Patel AV, Drill E, Harel S, Cela C, Tavazoie M, Christiano AM.

Genes Immun. 2017 Mar;18(2):100-104. doi: 10.1038/gene.2017.4. Epub 2017 Mar 16. No abstract available.

PMID:
28300058
24.

Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study.

Telomeres Mendelian Randomization Collaboration, Haycock PC, Burgess S, Nounu A, Zheng J, Okoli GN, Bowden J, Wade KH, Timpson NJ, Evans DM, Willeit P, Aviv A, Gaunt TR, Hemani G, Mangino M, Ellis HP, Kurian KM, Pooley KA, Eeles RA, Lee JE, Fang S, Chen WV, Law MH, Bowdler LM, Iles MM, Yang Q, Worrall BB, Markus HS, Hung RJ, Amos CI, Spurdle AB, Thompson DJ, O'Mara TA, Wolpin B, Amundadottir L, Stolzenberg-Solomon R, Trichopoulou A, Onland-Moret NC, Lund E, Duell EJ, Canzian F, Severi G, Overvad K, Gunter MJ, Tumino R, Svenson U, van Rij A, Baas AF, Bown MJ, Samani NJ, van t'Hof FNG, Tromp G, Jones GT, Kuivaniemi H, Elmore JR, Johansson M, Mckay J, Scelo G, Carreras-Torres R, Gaborieau V, Brennan P, Bracci PM, Neale RE, Olson SH, Gallinger S, Li D, Petersen GM, Risch HA, Klein AP, Han J, Abnet CC, Freedman ND, Taylor PR, Maris JM, Aben KK, Kiemeney LA, Vermeulen SH, Wiencke JK, Walsh KM, Wrensch M, Rice T, Turnbull C, Litchfield K, Paternoster L, Standl M, Abecasis GR, SanGiovanni JP, Li Y, Mijatovic V, Sapkota Y, Low SK, Zondervan KT, Montgomery GW, Nyholt DR, van Heel DA, Hunt K, Arking DE, Ashar FN, Sotoodehnia N, Woo D, Rosand J, Comeau ME, Brown WM, Silverman EK, Hokanson JE, Cho MH, Hui J, Ferreira MA, Thompson PJ, Morrison AC, Felix JF, Smith NL, Christiano AM, Petukhova L, Betz RC, Fan X, Zhang X, Zhu C, Langefeld CD, Thompson SD, Wang F, Lin X, Schwartz DA, Fingerlin T, Rotter JI, Cotch MF, Jensen RA, Munz M, Dommisch H, Schaefer AS, Han F, Ollila HM, Hillary RP, Albagha O, Ralston SH, Zeng C, Zheng W, Shu XO, Reis A, Uebe S, Hüffmeier U, Kawamura Y, Otowa T, Sasaki T, Hibberd ML, Davila S, Xie G, Siminovitch K, Bei JX, Zeng YX, Försti A, Chen B, Landi S, Franke A, Fischer A, Ellinghaus D, Flores C, Noth I, Ma SF, Foo JN, Liu J, Kim JW, Cox DG, Delattre O, Mirabeau O, Skibola CF, Tang CS, Garcia-Barcelo M, Chang KP, Su WH, Chang YS, Martin NG, Gordon S, Wade TD, Lee C, Kubo M, Cha PC, Nakamura Y, Levy D, Kimura M, Hwang SJ, Hunt S, Spector T, Soranzo N, Manichaikul AW, Barr RG, Kahali B, Speliotes E, Yerges-Armstrong LM, Cheng CY, Jonas JB, Wong TY, Fogh I, Lin K, Powell JF, Rice K, Relton CL, Martin RM, Davey Smith G.

JAMA Oncol. 2017 May 1;3(5):636-651. doi: 10.1001/jamaoncol.2016.5945.

25.

JAK-STAT Signaling Jump Starts the Hair Cycle.

Wang E, Harel S, Christiano AM.

J Invest Dermatol. 2016 Nov;136(11):2131-2132. doi: 10.1016/j.jid.2016.08.029. Review.

26.

Out of Many, One: Computational Reconstruction of Mouse Skin using Single-Cell Transcriptomics.

Chen JC, Christiano AM.

Cell Stem Cell. 2016 Oct 6;19(4):421-422. doi: 10.1016/j.stem.2016.09.009.

27.

Oral ruxolitinib induces hair regrowth in patients with moderate-to-severe alopecia areata.

Mackay-Wiggan J, Jabbari A, Nguyen N, Cerise JE, Clark C, Ulerio G, Furniss M, Vaughan R, Christiano AM, Clynes R.

JCI Insight. 2016 Sep 22;1(15):e89790.

28.

Safety and efficacy of the JAK inhibitor tofacitinib citrate in patients with alopecia areata.

Kennedy Crispin M, Ko JM, Craiglow BG, Li S, Shankar G, Urban JR, Chen JC, Cerise JE, Jabbari A, Winge MC, Marinkovich MP, Christiano AM, Oro AE, King BA.

JCI Insight. 2016 Sep 22;1(15):e89776.

29.

Multifaceted role of hair follicle dermal cells in bioengineered skins.

Higgins CA, Roger MF, Hill RP, Ali-Khan AS, Garlick JA, Christiano AM, Jahoda CAB.

Br J Dermatol. 2017 May;176(5):1259-1269. doi: 10.1111/bjd.15087. Epub 2017 Mar 14.

30.

CXCR3 Blockade Inhibits T Cell Migration into the Skin and Prevents Development of Alopecia Areata.

Dai Z, Xing L, Cerise J, Wang EH, Jabbari A, de Jong A, Petukhova L, Christiano AM, Clynes R.

J Immunol. 2016 Aug 15;197(4):1089-99. doi: 10.4049/jimmunol.1501798. Epub 2016 Jul 13.

31.

Human Skin Constructs with Spatially Controlled Vasculature Using Primary and iPSC-Derived Endothelial Cells.

Abaci HE, Guo Z, Coffman A, Gillette B, Lee WH, Sia SK, Christiano AM.

Adv Healthc Mater. 2016 Jul;5(14):1800-7. doi: 10.1002/adhm.201500936. Epub 2016 Jun 22.

32.

Molecular signatures define alopecia areata subtypes and transcriptional biomarkers.

Jabbari A, Cerise JE, Chen JC, Mackay-Wiggan J, Duvic M, Price V, Hordinsky M, Norris D, Clynes R, Christiano AM.

EBioMedicine. 2016 May;7:240-7. doi: 10.1016/j.ebiom.2016.03.036. Epub 2016 Mar 31.

33.

Genomewide analysis of copy number variants in alopecia areata in a Central European cohort reveals association with MCHR2.

Fischer J, Degenhardt F, Hofmann A, Redler S, Basmanav FB, Heilmann-Heimbach S, Hanneken S, Giehl KA, Wolff H, Moebus S, Kruse R, Lutz G, Blaumeiser B, Böhm M, Garcia Bartels N, Blume-Peytavi U, Petukhova L, Christiano AM, Nöthen MM, Betz RC.

Exp Dermatol. 2017 Jun;26(6):536-541. doi: 10.1111/exd.13123. Epub 2017 Mar 23.

PMID:
27306922
34.

Mechanisms and Disease Associations of Haplotype-Dependent Allele-Specific DNA Methylation.

Do C, Lang CF, Lin J, Darbary H, Krupska I, Gaba A, Petukhova L, Vonsattel JP, Gallagher MP, Goland RS, Clynes RA, Dwork A, Kral JG, Monk C, Christiano AM, Tycko B.

Am J Hum Genet. 2016 May 5;98(5):934-955. doi: 10.1016/j.ajhg.2016.03.027.

35.

Site-specific genome editing for correction of induced pluripotent stem cells derived from dominant dystrophic epidermolysis bullosa.

Shinkuma S, Guo Z, Christiano AM.

Proc Natl Acad Sci U S A. 2016 May 17;113(20):5676-81. doi: 10.1073/pnas.1512028113. Epub 2016 May 3.

36.

Treatment of an alopecia areata patient with tofacitinib results in regrowth of hair and changes in serum and skin biomarkers.

Jabbari A, Nguyen N, Cerise JE, Ulerio G, de Jong A, Clynes R, Christiano AM, Mackay-Wiggan J.

Exp Dermatol. 2016 Aug;25(8):642-3. doi: 10.1111/exd.13060. No abstract available.

37.

Sex differences in genomics in lupus: girls with systemic lupus have high interferon gene expression while boys have high levels of tumour necrosis factor-related gene expression.

Hui-Yuen JS, Christiano AM, Askanase A.

Scand J Rheumatol. 2016 Oct;45(5):394-6. doi: 10.3109/03009742.2015.1132760. Epub 2016 Feb 17.

PMID:
26885894
38.

Progress toward Treatment and Cure of Epidermolysis Bullosa: Summary of the DEBRA International Research Symposium EB2015.

Uitto J, Bruckner-Tuderman L, Christiano AM, McGrath JA, Has C, South AP, Kopelan B, Robinson EC.

J Invest Dermatol. 2016 Feb;136(2):352-8. doi: 10.1016/j.jid.2015.10.050. Review.

39.

Functional Interpretation of Genome-Wide Association Study Evidence in Alopecia Areata.

Petukhova L, Christiano AM.

J Invest Dermatol. 2016 Jan;136(1):314-7. doi: 10.1038/JID.2015.402. No abstract available.

40.

Rapid skin repigmentation on oral ruxolitinib in a patient with coexistent vitiligo and alopecia areata (AA).

Harris JE, Rashighi M, Nguyen N, Jabbari A, Ulerio G, Clynes R, Christiano AM, Mackay-Wiggan J.

J Am Acad Dermatol. 2016 Feb;74(2):370-1. doi: 10.1016/j.jaad.2015.09.073. Epub 2015 Dec 11. No abstract available.

41.

Master regulators of infiltrate recruitment in autoimmune disease identified through network-based molecular deconvolution.

Chen JC, Cerise JE, Jabbari A, Clynes R, Christiano AM.

Cell Syst. 2015 Nov 25;1(5):326-337.

42.

Pharmacologic inhibition of JAK-STAT signaling promotes hair growth.

Harel S, Higgins CA, Cerise JE, Dai Z, Chen JC, Clynes R, Christiano AM.

Sci Adv. 2015 Oct 23;1(9):e1500973. doi: 10.1126/sciadv.1500973. eCollection 2015 Oct.

43.

Melanin Transfer in Human 3D Skin Equivalents Generated Exclusively from Induced Pluripotent Stem Cells.

Gledhill K, Guo Z, Umegaki-Arao N, Higgins CA, Itoh M, Christiano AM.

PLoS One. 2015 Aug 26;10(8):e0136713. doi: 10.1371/journal.pone.0136713. eCollection 2015.

44.

Reduced Toxicity Conditioning and Allogeneic Hematopoietic Progenitor Cell Transplantation for Recessive Dystrophic Epidermolysis Bullosa.

Geyer MB, Radhakrishnan K, Giller R, Umegaki N, Harel S, Kiuru M, Morel KD, LeBoeuf N, Kandel J, Bruckner A, Fabricatore S, Chen M, Woodley D, McGrath J, Baxter-Lowe L, Uitto J, Christiano AM, Cairo MS.

J Pediatr. 2015 Sep;167(3):765-9.e1. doi: 10.1016/j.jpeds.2015.05.051. Epub 2015 Jul 3.

PMID:
26148662
45.

Reversal of Alopecia Areata Following Treatment With the JAK1/2 Inhibitor Baricitinib.

Jabbari A, Dai Z, Xing L, Cerise JE, Ramot Y, Berkun Y, Sanchez GA, Goldbach-Mansky R, Christiano AM, Clynes R, Zlotogorski A.

EBioMedicine. 2015 Feb 26;2(4):351-5. doi: 10.1016/j.ebiom.2015.02.015. eCollection 2015 Apr.

46.

PI3K/AKT pathway regulates E-cadherin and Desmoglein 2 in aggressive prostate cancer.

Barber AG, Castillo-Martin M, Bonal DM, Jia AJ, Rybicki BA, Christiano AM, Cordon-Cardo C.

Cancer Med. 2015 Aug;4(8):1258-71. doi: 10.1002/cam4.463. Epub 2015 May 29.

47.

Rescue of the mucocutaneous manifestations by human cord blood derived nonhematopoietic stem cells in a mouse model of recessive dystrophic epidermolysis bullosa.

Liao Y, Ivanova L, Zhu H, Yahr A, Ayello J, van de Ven C, Rashad A, Uitto J, Christiano AM, Cairo MS.

Stem Cells. 2015 Jun;33(6):1807-17. doi: 10.1002/stem.1966.

48.

Genome-wide meta-analysis in alopecia areata resolves HLA associations and reveals two new susceptibility loci.

Betz RC, Petukhova L, Ripke S, Huang H, Menelaou A, Redler S, Becker T, Heilmann S, Yamany T, Duvic M, Hordinsky M, Norris D, Price VH, Mackay-Wiggan J, de Jong A, DeStefano GM, Moebus S, Böhm M, Blume-Peytavi U, Wolff H, Lutz G, Kruse R, Bian L, Amos CI, Lee A, Gregersen PK, Blaumeiser B, Altshuler D, Clynes R, de Bakker PIW, Nöthen MM, Daly MJ, Christiano AM.

Nat Commun. 2015 Jan 22;6:5966. doi: 10.1038/ncomms6966.

49.

Pumpless microfluidic platform for drug testing on human skin equivalents.

Abaci HE, Gledhill K, Guo Z, Christiano AM, Shuler ML.

Lab Chip. 2015 Feb 7;15(3):882-8. doi: 10.1039/c4lc00999a.

50.

Induced pluripotent stem cells from human revertant keratinocytes for the treatment of epidermolysis bullosa.

Umegaki-Arao N, Pasmooij AM, Itoh M, Cerise JE, Guo Z, Levy B, Gostyński A, Rothman LR, Jonkman MF, Christiano AM.

Sci Transl Med. 2014 Nov 26;6(264):264ra164. doi: 10.1126/scitranslmed.3009342.

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