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Items: 50


CRISPR Knockouts in Ciona Embryos.

Gandhi S, Razy-Krajka F, Christiaen L, Stolfi A.

Adv Exp Med Biol. 2018;1029:141-152. doi: 10.1007/978-981-10-7545-2_13.


Purification of Fluorescent Labeled Cells from Dissociated Ciona Embryos.

Wang W, Racioppi C, Gravez B, Christiaen L.

Adv Exp Med Biol. 2018;1029:101-107. doi: 10.1007/978-981-10-7545-2_9.


An FGF-driven feed-forward circuit patterns the cardiopharyngeal mesoderm in space and time.

Razy-Krajka F, Gravez B, Kaplan N, Racioppi C, Wang W, Christiaen L.

Elife. 2018 Feb 6;7. pii: e29656. doi: 10.7554/eLife.29656.


Evolutionary recruitment of flexible Esrp-dependent splicing programs into diverse embryonic morphogenetic processes.

Burguera D, Marquez Y, Racioppi C, Permanyer J, Torres-Méndez A, Esposito R, Albuixech-Crespo B, Fanlo L, D'Agostino Y, Gohr A, Navas-Perez E, Riesgo A, Cuomo C, Benvenuto G, Christiaen LA, Martí E, D'Aniello S, Spagnuolo A, Ristoratore F, Arnone MI, Garcia-Fernàndez J, Irimia M.

Nat Commun. 2017 Nov 27;8(1):1799. doi: 10.1038/s41467-017-01961-y.


ANISEED 2017: extending the integrated ascidian database to the exploration and evolutionary comparison of genome-scale datasets.

Brozovic M, Dantec C, Dardaillon J, Dauga D, Faure E, Gineste M, Louis A, Naville M, Nitta KR, Piette J, Reeves W, Scornavacca C, Simion P, Vincentelli R, Bellec M, Aicha SB, Fagotto M, Guéroult-Bellone M, Haeussler M, Jacox E, Lowe EK, Mendez M, Roberge A, Stolfi A, Yokomori R, Brown CT, Cambillau C, Christiaen L, Delsuc F, Douzery E, Dumollard R, Kusakabe T, Nakai K, Nishida H, Satou Y, Swalla B, Veeman M, Volff JN, Lemaire P.

Nucleic Acids Res. 2018 Jan 4;46(D1):D718-D725. doi: 10.1093/nar/gkx1108.


Evolutionary loss of melanogenesis in the tunicate Molgula occulta.

Racioppi C, Valoroso MC, Coppola U, Lowe EK, Brown CT, Swalla BJ, Christiaen L, Stolfi A, Ristoratore F.

Evodevo. 2017 Jul 18;8:11. doi: 10.1186/s13227-017-0074-x. eCollection 2017.


Evaluation and rational design of guide RNAs for efficient CRISPR/Cas9-mediated mutagenesis in Ciona.

Gandhi S, Haeussler M, Razy-Krajka F, Christiaen L, Stolfi A.

Dev Biol. 2017 May 1;425(1):8-20. doi: 10.1016/j.ydbio.2017.03.003. Epub 2017 Mar 22.


Fused Regression for Multi-source Gene Regulatory Network Inference.

Lam KY, Westrick ZM, Müller CL, Christiaen L, Bonneau R.

PLoS Comput Biol. 2016 Dec 6;12(12):e1005157. doi: 10.1371/journal.pcbi.1005157. eCollection 2016 Dec.


Ciona as a Simple Chordate Model for Heart Development and Regeneration.

Anderson HE, Christiaen L.

J Cardiovasc Dev Dis. 2016 Sep;3(3). pii: 25. Epub 2016 Aug 9.


Transcriptional Control of Developmental Cell Behaviors.

Bernadskaya Y, Christiaen L.

Annu Rev Cell Dev Biol. 2016 Oct 6;32:77-101. Epub 2016 Aug 8. Review.


Migratory neuronal progenitors arise from the neural plate borders in tunicates.

Stolfi A, Ryan K, Meinertzhagen IA, Christiaen L.

Nature. 2015 Nov 19;527(7578):371-4. doi: 10.1038/nature15758. Epub 2015 Oct 28.


A new heart for a new head in vertebrate cardiopharyngeal evolution.

Diogo R, Kelly RG, Christiaen L, Levine M, Ziermann JM, Molnar JL, Noden DM, Tzahor E.

Nature. 2015 Apr 23;520(7548):466-73. doi: 10.1038/nature14435. Review.


Regulation and evolution of cardiopharyngeal cell identity and behavior: insights from simple chordates.

Kaplan N, Razy-Krajka F, Christiaen L.

Curr Opin Genet Dev. 2015 Jun;32:119-28. doi: 10.1016/j.gde.2015.02.008. Epub 2015 Mar 25. Review.


Surrounding tissues canalize motile cardiopharyngeal progenitors towards collective polarity and directed migration.

Gline S, Kaplan N, Bernadskaya Y, Abdu Y, Christiaen L.

Development. 2015 Feb 1;142(3):544-54. doi: 10.1242/dev.115444. Epub 2015 Jan 6.


Tissue-specific genome editing in Ciona embryos by CRISPR/Cas9.

Stolfi A, Gandhi S, Salek F, Christiaen L.

Development. 2014 Nov;141(21):4115-20. doi: 10.1242/dev.114488.


Guidelines for the nomenclature of genetic elements in tunicate genomes.

Stolfi A, Sasakura Y, Chalopin D, Satou Y, Christiaen L, Dantec C, Endo T, Naville M, Nishida H, Swalla BJ, Volff JN, Voskoboynik A, Dauga D, Lemaire P.

Genesis. 2015 Jan;53(1):1-14. doi: 10.1002/dvg.22822. Epub 2014 Oct 3.


Divergent mechanisms regulate conserved cardiopharyngeal development and gene expression in distantly related ascidians.

Stolfi A, Lowe EK, Racioppi C, Ristoratore F, Brown CT, Swalla BJ, Christiaen L.

Elife. 2014 Sep 10;3:e03728. doi: 10.7554/eLife.03728.


Fibroblast growth factor signalling controls nervous system patterning and pigment cell formation in Ciona intestinalis.

Racioppi C, Kamal AK, Razy-Krajka F, Gambardella G, Zanetti L, di Bernardo D, Sanges R, Christiaen LA, Ristoratore F.

Nat Commun. 2014 Sep 5;5:4830. doi: 10.1038/ncomms5830.


Collier/OLF/EBF-dependent transcriptional dynamics control pharyngeal muscle specification from primed cardiopharyngeal progenitors.

Razy-Krajka F, Lam K, Wang W, Stolfi A, Joly M, Bonneau R, Christiaen L.

Dev Cell. 2014 May 12;29(3):263-76. doi: 10.1016/j.devcel.2014.04.001. Epub 2014 May 1.


NK4 antagonizes Tbx1/10 to promote cardiac versus pharyngeal muscle fate in the ascidian second heart field.

Wang W, Razy-Krajka F, Siu E, Ketcham A, Christiaen L.

PLoS Biol. 2013 Dec;11(12):e1001725. doi: 10.1371/journal.pbio.1001725. Epub 2013 Dec 3.


Cis-regulatory timers for developmental gene expression.

Christiaen L.

PLoS Biol. 2013 Oct;11(10):e1001698. doi: 10.1371/journal.pbio.1001698. Epub 2013 Oct 29.


p120RasGAP mediates ephrin/Eph-dependent attenuation of FGF/ERK signals during cell fate specification in ascidian embryos.

Haupaix N, Stolfi A, Sirour C, Picco V, Levine M, Christiaen L, Yasuo H.

Development. 2013 Nov;140(21):4347-52. doi: 10.1242/dev.098756. Epub 2013 Sep 25.


Genetic and genomic toolbox of the chordate Ciona intestinalis.

Stolfi A, Christiaen L.

Genetics. 2012 Sep;192(1):55-66. doi: 10.1534/genetics.112.140590. Review.


Development and evolution of the ascidian cardiogenic mesoderm.

Tolkin T, Christiaen L.

Curr Top Dev Biol. 2012;100:107-42. doi: 10.1016/B978-0-12-387786-4.00011-7. Review.


Developmental cell behavior.

Christiaen L.

Semin Cell Dev Biol. 2012 May;23(3):289. doi: 10.1016/j.semcdb.2012.03.012. Epub 2012 Mar 15. No abstract available.


Transcriptional enhancers in ascidian development.

Wang W, Christiaen L.

Curr Top Dev Biol. 2012;98:147-72. doi: 10.1016/B978-0-12-386499-4.00006-9. Review.


Early chordate origins of the vertebrate second heart field.

Stolfi A, Gainous TB, Young JJ, Mori A, Levine M, Christiaen L.

Science. 2010 Jul 30;329(5991):565-8. doi: 10.1126/science.1190181.


The ANISEED database: digital representation, formalization, and elucidation of a chordate developmental program.

Tassy O, Dauga D, Daian F, Sobral D, Robin F, Khoueiry P, Salgado D, Fox V, Caillol D, Schiappa R, Laporte B, Rios A, Luxardi G, Kusakabe T, Joly JS, Darras S, Christiaen L, Contensin M, Auger H, Lamy C, Hudson C, Rothbächer U, Gilchrist MJ, Makabe KW, Hotta K, Fujiwara S, Satoh N, Satou Y, Lemaire P.

Genome Res. 2010 Oct;20(10):1459-68. doi: 10.1101/gr.108175.110. Epub 2010 Jul 20.


A cis-regulatory signature for chordate anterior neuroectodermal genes.

Haeussler M, Jaszczyszyn Y, Christiaen L, Joly JS.

PLoS Genet. 2010 Apr 15;6(4):e1000912. doi: 10.1371/journal.pgen.1000912.


Isolation of individual cells and tissues from electroporated sea squirt (Ciona) embryos by fluorescence-activated cell sorting (FACS).

Christiaen L, Wagner E, Shi W, Levine M.

Cold Spring Harb Protoc. 2009 Dec;2009(12):pdb.prot5349. doi: 10.1101/pdb.prot5349. No abstract available.


Whole-mount in situ hybridization on sea squirt (Ciona intestinalis) embryos.

Christiaen L, Wagner E, Shi W, Levine M.

Cold Spring Harb Protoc. 2009 Dec;2009(12):pdb.prot5348. doi: 10.1101/pdb.prot5348. No abstract available.


Microinjection of morpholino oligos and RNAs in sea squirt (Ciona) embryos.

Christiaen L, Wagner E, Shi W, Levine M.

Cold Spring Harb Protoc. 2009 Dec;2009(12):pdb.prot5347. doi: 10.1101/pdb.prot5347. No abstract available.


X-gal staining of electroporated sea squirt (Ciona) embryos.

Christiaen L, Wagner E, Shi W, Levine M.

Cold Spring Harb Protoc. 2009 Dec;2009(12):pdb.prot5346. doi: 10.1101/pdb.prot5346. No abstract available.


Electroporation of transgenic DNAs in the sea squirt Ciona.

Christiaen L, Wagner E, Shi W, Levine M.

Cold Spring Harb Protoc. 2009 Dec;2009(12):pdb.prot5345. doi: 10.1101/pdb.prot5345. No abstract available.


Isolation of sea squirt (Ciona) gametes, fertilization, dechorionation, and development.

Christiaen L, Wagner E, Shi W, Levine M.

Cold Spring Harb Protoc. 2009 Dec;2009(12):pdb.prot5344. doi: 10.1101/pdb.prot5344. No abstract available.


The sea squirt Ciona intestinalis.

Christiaen L, Wagner E, Shi W, Levine M.

Cold Spring Harb Protoc. 2009 Dec;2009(12):pdb.emo138. doi: 10.1101/pdb.emo138. No abstract available.


BMP signaling coordinates gene expression and cell migration during precardiac mesoderm development.

Christiaen L, Stolfi A, Levine M.

Dev Biol. 2010 Apr 15;340(2):179-87. doi: 10.1016/j.ydbio.2009.11.006. Epub 2009 Nov 10.


Spatio-temporal intersection of Lhx3 and Tbx6 defines the cardiac field through synergistic activation of Mesp.

Christiaen L, Stolfi A, Davidson B, Levine M.

Dev Biol. 2009 Apr 15;328(2):552-60. doi: 10.1016/j.ydbio.2009.01.033. Epub 2009 Feb 3.


The transcription/migration interface in heart precursors of Ciona intestinalis.

Christiaen L, Davidson B, Kawashima T, Powell W, Nolla H, Vranizan K, Levine M.

Science. 2008 Jun 6;320(5881):1349-52. doi: 10.1126/science.1158170.


FoxF is essential for FGF-induced migration of heart progenitor cells in the ascidian Ciona intestinalis.

Beh J, Shi W, Levine M, Davidson B, Christiaen L.

Development. 2007 Sep;134(18):3297-305.


Evolutionary modification of mouth position in deuterostomes.

Christiaen L, Jaszczyszyn Y, Kerfant M, Kano S, Thermes V, Joly JS.

Semin Cell Dev Biol. 2007 Aug;18(4):502-11. Epub 2007 Jun 15. Review.


FGF signaling delineates the cardiac progenitor field in the simple chordate, Ciona intestinalis.

Davidson B, Shi W, Beh J, Christiaen L, Levine M.

Genes Dev. 2006 Oct 1;20(19):2728-38.


Linking chordate gene networks to cellular behavior in ascidians.

Davidson B, Christiaen L.

Cell. 2006 Jan 27;124(2):247-50. Review.


Regulatory gene expressions in the ascidian ventral sensory vesicle: evolutionary relationships with the vertebrate hypothalamus.

Moret F, Christiaen L, Deyts C, Blin M, Vernier P, Joly JS.

Dev Biol. 2005 Jan 15;277(2):567-79.


A modular cis-regulatory system controls isoform-specific pitx expression in ascidian stomodaeum.

Christiaen L, Bourrat F, Joly JS.

Dev Biol. 2005 Jan 15;277(2):557-66.


Embryonic versus blastogenetic development in the compound ascidian Botryllus schlosseri: insights from Pitx expression patterns.

Tiozzo S, Christiaen L, Deyts C, Manni L, Joly JS, Burighel P.

Dev Dyn. 2005 Feb;232(2):468-78.


Culture of adult ascidians and ascidian genetics.

Hendrickson C, Christiaen L, Deschet K, Jiang D, Joly JS, Legendre L, Nakatani Y, Tresser J, Smith WC.

Methods Cell Biol. 2004;74:143-70. Review. No abstract available.


Pitx genes in Tunicates provide new molecular insight into the evolutionary origin of pituitary.

Christiaen L, Burighel P, Smith WC, Vernier P, Bourrat F, Joly JS.

Gene. 2002 Apr 3;287(1-2):107-13.


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