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Items: 1 to 50 of 226

1.

α-Conotoxin VnIB from Conus ventricosus is a potent and selective antagonist of α6β4* nicotinic acetylcholine receptors.

van Hout M, Valdes A, Christensen SB, Tran PT, Watkins M, Gajewiak J, Jensen AA, Olivera BM, McIntosh JM.

Neuropharmacology. 2019 Oct;157:107691. doi: 10.1016/j.neuropharm.2019.107691. Epub 2019 Jun 28.

PMID:
31255696
2.

Catabolic activity of osteoblast lineage cells contributes to osteoclastic bone resorption in vitro.

Pirapaharan DC, Olesen JB, Andersen TL, Christensen SB, Kjærsgaard-Andersen P, Delaisse JM, Søe K.

J Cell Sci. 2019 May 15;132(10). pii: jcs229351. doi: 10.1242/jcs.229351.

PMID:
30975918
3.

Identification and Optimization of Novel Small c-Abl Kinase Activators Using Fragment and HTS Methodologies.

Simpson GL, Bertrand SM, Borthwick JA, Campobasso N, Chabanet J, Chen S, Coggins J, Cottom J, Christensen SB, Dawson HC, Evans HL, Hobbs AN, Hong X, Mangatt B, Munoz-Muriedas J, Oliff A, Qin D, Scott-Stevens P, Ward P, Washio Y, Yang J, Young RJ.

J Med Chem. 2019 Feb 28;62(4):2154-2171. doi: 10.1021/acs.jmedchem.8b01872. Epub 2019 Feb 11.

PMID:
30689376
4.

Biosynthesis of tovarol and other sesquiterpenoids in Thapsia laciniata Rouy.

Andersen TB, Rasmussen SA, Christensen SB, Simonsen HT.

Phytochemistry. 2019 Jan;157:168-174. doi: 10.1016/j.phytochem.2018.10.027. Epub 2018 Nov 6.

PMID:
30412824
5.

Studies on acid stability and solid-phase block synthesis of peptide-peptoid hybrids: ligands for formyl peptide receptors.

Hansen AM, Skovbakke SL, Christensen SB, Perez-Gassol I, Franzyk H.

Amino Acids. 2019 Feb;51(2):205-218. doi: 10.1007/s00726-018-2656-x. Epub 2018 Sep 28.

PMID:
30267164
6.

Nonlinear relationship between ER Ca2+ depletion versus induction of the unfolded protein response, autophagy inhibition, and cell death.

Szalai P, Parys JB, Bultynck G, Christensen SB, Nissen P, Møller JV, Engedal N.

Cell Calcium. 2018 Dec;76:48-61. doi: 10.1016/j.ceca.2018.09.005. Epub 2018 Sep 17.

PMID:
30261424
7.

Phorbol Rearrangements.

Zimmermann T, Franzyk H, Christensen SB.

J Nat Prod. 2018 Sep 28;81(9):2134-2137. doi: 10.1021/acs.jnatprod.8b00607. Epub 2018 Sep 14.

PMID:
30216064
8.

Preparation of Enzyme-Activated Thapsigargin Prodrugs by Solid-Phase Synthesis.

Zimmermann T, Christensen SB, Franzyk H.

Molecules. 2018 Jun 15;23(6). pii: E1463. doi: 10.3390/molecules23061463.

9.

Lactam hybrid analogues of solonamide B and autoinducing peptides as potent S. aureus AgrC antagonists.

Hansen AM, Peng P, Baldry M, Perez-Gassol I, Christensen SB, Vinther JMO, Ingmer H, Franzyk H.

Eur J Med Chem. 2018 May 25;152:370-376. doi: 10.1016/j.ejmech.2018.04.053. Epub 2018 Apr 28.

PMID:
29738955
10.

A new flavonol glycoside and other flavonoids from the aerial parts of Taverniera aegyptiaca.

Hassan AR, Amer KF, El-Toumy SA, Nielsen J, Christensen SB.

Nat Prod Res. 2019 Apr;33(8):1135-1139. doi: 10.1080/14786419.2018.1460834. Epub 2018 Apr 17.

PMID:
29663839
11.

CELSR2 is a candidate susceptibility gene in idiopathic scoliosis.

Einarsdottir E, Grauers A, Wang J, Jiao H, Escher SA, Danielsson A, Simony A, Andersen M, Christensen SB, Åkesson K, Kou I, Khanshour AM, Ohlin A, Wise C, Ikegawa S, Kere J, Gerdhem P.

PLoS One. 2017 Dec 14;12(12):e0189591. doi: 10.1371/journal.pone.0189591. eCollection 2017.

12.

LEGO-Inspired Drug Design: Unveiling a Class of Benzo[d]thiazoles Containing a 3,4-Dihydroxyphenyl Moiety as Plasma Membrane H+ -ATPase Inhibitors.

Tung TT, Dao TT, Junyent MG, Palmgren M, Günther-Pomorski T, Fuglsang AT, Christensen SB, Nielsen J.

ChemMedChem. 2018 Jan 8;13(1):37-47. doi: 10.1002/cmdc.201700635. Epub 2017 Dec 7.

PMID:
29139202
13.

Local dynamic stability during treadmill walking can detect children with developmental coordination disorder.

Speedtsberg MB, Christensen SB, Stenum J, Kallemose T, Bencke J, Curtis DJ, Jensen BR.

Gait Posture. 2018 Jan;59:99-103. doi: 10.1016/j.gaitpost.2017.09.035. Epub 2017 Oct 5.

PMID:
29028627
14.

Inhibition of the sarco/endoplasmic reticulum (ER) Ca2+-ATPase by thapsigargin analogs induces cell death via ER Ca2+ depletion and the unfolded protein response.

Sehgal P, Szalai P, Olesen C, Praetorius HA, Nissen P, Christensen SB, Engedal N, Møller JV.

J Biol Chem. 2017 Dec 1;292(48):19656-19673. doi: 10.1074/jbc.M117.796920. Epub 2017 Sep 29.

15.

Difluoroacetic Acid as a New Reagent for Direct C-H Difluoromethylation of Heteroaromatic Compounds.

Tung TT, Christensen SB, Nielsen J.

Chemistry. 2017 Dec 22;23(72):18125-18128. doi: 10.1002/chem.201704261. Epub 2017 Oct 11.

PMID:
28945302
16.

Metformin, an Anthropogenic Contaminant of Seidlitzia rosmarinus Collected in a Desert Region near the Gulf of Aqaba, Sinai Peninsula.

Hassan AR, El-Kousy SM, El-Toumy SA, Frydenvang K, Tung TT, Olsen J, Nielsen J, Christensen SB.

J Nat Prod. 2017 Oct 27;80(10):2830-2834. doi: 10.1021/acs.jnatprod.7b00106. Epub 2017 Sep 20.

PMID:
28930456
17.

RgIA4 Potently Blocks Mouse α9α10 nAChRs and Provides Long Lasting Protection against Oxaliplatin-Induced Cold Allodynia.

Christensen SB, Hone AJ, Roux I, Kniazeff J, Pin JP, Upert G, Servent D, Glowatzki E, McIntosh JM.

Front Cell Neurosci. 2017 Jul 21;11:219. doi: 10.3389/fncel.2017.00219. eCollection 2017.

18.

On-resin N-formylation of peptides: a head-to-head comparison of reagents in solid-phase synthesis of ligands for formyl peptide receptors.

Christensen SB, Hansen AM, Franzyk H.

J Pept Sci. 2017 May;23(5):410-415. doi: 10.1002/psc.2998.

PMID:
28421689
19.

Cranberry Juice and Combinations of Its Organic Acids Are Effective against Experimental Urinary Tract Infection.

Jensen HD, Struve C, Christensen SB, Krogfelt KA.

Front Microbiol. 2017 Apr 4;8:542. doi: 10.3389/fmicb.2017.00542. eCollection 2017.

20.

Localization and in-Vivo Characterization of Thapsia garganica CYP76AE2 Indicates a Role in Thapsigargin Biosynthesis.

Andersen TB, Martinez-Swatson KA, Rasmussen SA, Boughton BA, Jørgensen K, Andersen-Ranberg J, Nyberg N, Christensen SB, Simonsen HT.

Plant Physiol. 2017 May;174(1):56-72. doi: 10.1104/pp.16.00055. Epub 2017 Mar 8.

21.

Structure/activity relationship of thapsigargin inhibition on the purified Golgi/secretory pathway Ca2+/Mn2+-transport ATPase (SPCA1a).

Chen J, De Raeymaecker J, Hovgaard JB, Smaardijk S, Vandecaetsbeek I, Wuytack F, Møller JV, Eggermont J, De Maeyer M, Christensen SB, Vangheluwe P.

J Biol Chem. 2017 Apr 28;292(17):6938-6951. doi: 10.1074/jbc.M117.778431. Epub 2017 Mar 6.

22.

Accelerating the Domestication of New Crops: Feasibility and Approaches.

Østerberg JT, Xiang W, Olsen LI, Edenbrandt AK, Vedel SE, Christiansen A, Landes X, Andersen MM, Pagh P, Sandøe P, Nielsen J, Christensen SB, Thorsen BJ, Kappel K, Gamborg C, Palmgren M.

Trends Plant Sci. 2017 May;22(5):373-384. doi: 10.1016/j.tplants.2017.01.004. Epub 2017 Mar 2. Review.

PMID:
28262427
23.

Inhibition of α9α10 nicotinic acetylcholine receptors prevents chemotherapy-induced neuropathic pain.

Romero HK, Christensen SB, Di Cesare Mannelli L, Gajewiak J, Ramachandra R, Elmslie KS, Vetter DE, Ghelardini C, Iadonato SP, Mercado JL, Olivera BM, McIntosh JM.

Proc Natl Acad Sci U S A. 2017 Mar 7;114(10):E1825-E1832. doi: 10.1073/pnas.1621433114. Epub 2017 Feb 21.

24.

Fusaric acid and analogues as Gram-negative bacterial quorum sensing inhibitors.

Tung TT, Jakobsen TH, Dao TT, Fuglsang AT, Givskov M, Christensen SB, Nielsen J.

Eur J Med Chem. 2017 Jan 27;126:1011-1020. doi: 10.1016/j.ejmech.2016.11.044. Epub 2016 Nov 24.

PMID:
28033578
25.

Impaired postural control in children with developmental coordination disorder is related to less efficient central as well as peripheral control.

Speedtsberg MB, Christensen SB, Andersen KK, Bencke J, Jensen BR, Curtis DJ.

Gait Posture. 2017 Jan;51:1-6. doi: 10.1016/j.gaitpost.2016.09.019. Epub 2016 Sep 24.

PMID:
27693806
26.

Demethoxycurcumin Is A Potent Inhibitor of P-Type ATPases from Diverse Kingdoms of Life.

Dao TT, Sehgal P, Tung TT, Møller JV, Nielsen J, Palmgren M, Christensen SB, Fuglsang AT.

PLoS One. 2016 Sep 19;11(9):e0163260. doi: 10.1371/journal.pone.0163260. eCollection 2016.

27.

Incidence of cancer in adolescent idiopathic scoliosis patients treated 25 years previously.

Simony A, Hansen EJ, Christensen SB, Carreon LY, Andersen MO.

Eur Spine J. 2016 Oct;25(10):3366-3370. Epub 2016 Sep 3.

PMID:
27592106
28.

Iminolactones as tools for inversion of the absolute configuration of α-amino acids and as inhibitors of cancer cell proliferation.

Jensen CM, Chow HQ, Chen M, Zhai L, Frydenvang K, Liu H, Franzyk H, Christensen SB.

Eur J Med Chem. 2016 May 23;114:118-33. doi: 10.1016/j.ejmech.2016.02.037. Epub 2016 Feb 23.

PMID:
26974380
29.

Body weight-supported training in Becker and limb girdle 2I muscular dystrophy.

Jensen BR, Berthelsen MP, Husu E, Christensen SB, Prahm KP, Vissing J.

Muscle Nerve. 2016 Aug;54(2):239-43. doi: 10.1002/mus.25039. Epub 2016 May 19.

PMID:
26773840
30.

The agr Inhibitors Solonamide B and Analogues Alter Immune Responses to Staphylococccus aureus but Do Not Exhibit Adverse Effects on Immune Cell Functions.

Baldry M, Kitir B, Frøkiær H, Christensen SB, Taverne N, Meijerink M, Franzyk H, Olsen CA, Wells JM, Ingmer H.

PLoS One. 2016 Jan 5;11(1):e0145618. doi: 10.1371/journal.pone.0145618. eCollection 2016.

31.

Antidepressant use and risk for mortality in 121,252 heart failure patients with or without a diagnosis of clinical depression.

Brouwers C, Christensen SB, Damen NL, Denollet J, Torp-Pedersen C, Gislason GH, Pedersen SS.

Int J Cardiol. 2016 Jan 15;203:867-73. doi: 10.1016/j.ijcard.2015.11.032. Epub 2015 Nov 6.

32.

Thapsigargin, Origin, Chemistry, Structure-Activity Relationships and Prodrug Development.

Quynh Doan NT, Christensen SB.

Curr Pharm Des. 2015;21(38):5501-17. Review.

PMID:
26429715
33.

Radiological Outcomes in Adolescent Idiopathic Scoliosis Patients More Than 22 Years After Treatment.

Simony A, Christensen SB, Carreon LY, Andersen MO.

Spine Deform. 2015 Sep;3(5):436-439. doi: 10.1016/j.jspd.2015.03.003. Epub 2015 Oct 2.

PMID:
27927529
34.

Health-related quality-of-life in adolescent idiopathic scoliosis patients 25 years after treatment.

Simony A, Hansen EJ, Carreon LY, Christensen SB, Andersen MO.

Scoliosis. 2015 Jul 16;10:22. doi: 10.1186/s13013-015-0045-8. eCollection 2015.

35.

Chemo- and Regioselective Functionalization of Nortrilobolide: Application for Semisynthesis of the Natural Product 2-Acetoxytrilobolide.

Doan NT, Crestey F, Olsen CE, Christensen SB.

J Nat Prod. 2015 Jun 26;78(6):1406-14. doi: 10.1021/acs.jnatprod.5b00333. Epub 2015 Jun 16.

PMID:
26078214
36.

αS-conotoxin GVIIIB potently and selectively blocks α9α10 nicotinic acetylcholine receptors.

Christensen SB, Bandyopadhyay PK, Olivera BM, McIntosh JM.

Biochem Pharmacol. 2015 Aug 15;96(4):349-56. doi: 10.1016/j.bcp.2015.06.007. Epub 2015 Jun 11.

37.

Candidate gene analysis and exome sequencing confirm LBX1 as a susceptibility gene for idiopathic scoliosis.

Grauers A, Wang J, Einarsdottir E, Simony A, Danielsson A, Åkesson K, Ohlin A, Halldin K, Grabowski P, Tenne M, Laivuori H, Dahlman I, Andersen M, Christensen SB, Karlsson MK, Jiao H, Kere J, Gerdhem P.

Spine J. 2015 Oct 1;15(10):2239-46. doi: 10.1016/j.spinee.2015.05.013. Epub 2015 May 15.

PMID:
25987191
38.

Iminolactones from Schizophyllum commune.

Liu X, Frydenvang K, Liu H, Zhai L, Chen M, Olsen CE, Christensen SB.

J Nat Prod. 2015 May 22;78(5):1165-8. doi: 10.1021/np500836y. Epub 2015 May 7.

PMID:
25951057
39.

Effect of moderate- versus high-intensity exercise on vascular function, biomarkers and quality of life in heart transplant recipients: A randomized, crossover trial.

Dall CH, Gustafsson F, Christensen SB, Dela F, Langberg H, Prescott E.

J Heart Lung Transplant. 2015 Aug;34(8):1033-41. doi: 10.1016/j.healun.2015.02.001. Epub 2015 Feb 7.

PMID:
25840503
40.

Use of quinine and mortality-risk in patients with heart failure--a Danish nationwide observational study.

Gjesing A, Gislason GH, Christensen SB, Jørgensen ME, Mérie C, Norgaard ML, Poulsen HE, Gustafsson F, Køber L, Torp-Pedersen C, Andersson C.

Pharmacoepidemiol Drug Saf. 2015 Mar;24(3):310-8. doi: 10.1002/pds.3746. Epub 2015 Feb 4.

PMID:
25656791
41.

Are we ready for back-to-nature crop breeding?

Palmgren MG, Edenbrandt AK, Vedel SE, Andersen MM, Landes X, Østerberg JT, Falhof J, Olsen LI, Christensen SB, Sandøe P, Gamborg C, Kappel K, Thorsen BJ, Pagh P.

Trends Plant Sci. 2015 Mar;20(3):155-64. doi: 10.1016/j.tplants.2014.11.003. Epub 2014 Dec 16. Review.

PMID:
25529373
42.

Nationwide trends in development of heart failure and mortality after first-time myocardial infarction 1997-2010: A Danish cohort study.

Gjesing A, Gislason GH, Køber L, Gustav Smith J, Christensen SB, Gustafsson F, Olsen AM, Torp-Pedersen C, Andersson C.

Eur J Intern Med. 2014 Oct;25(8):731-8. doi: 10.1016/j.ejim.2014.08.009. Epub 2014 Sep 16.

PMID:
25225051
43.

Targeting thapsigargin towards tumors.

Doan NT, Paulsen ES, Sehgal P, Møller JV, Nissen P, Denmeade SR, Isaacs JT, Dionne CA, Christensen SB.

Steroids. 2015 May;97:2-7. doi: 10.1016/j.steroids.2014.07.009. Epub 2014 Jul 24. Review.

44.

Anti-gravity training improves walking capacity and postural balance in patients with muscular dystrophy.

Berthelsen MP, Husu E, Christensen SB, Prahm KP, Vissing J, Jensen BR.

Neuromuscul Disord. 2014 Jun;24(6):492-8. doi: 10.1016/j.nmd.2014.03.001. Epub 2014 Mar 12.

PMID:
24684860
45.

Interval training does not modulate diastolic function in heart transplant recipients.

Monk-Hansen T, Dall CH, Christensen SB, Snoer M, Gustafsson F, Rasmusen H, Prescott E.

Scand Cardiovasc J. 2014 Apr;48(2):91-8. doi: 10.3109/14017431.2013.871058. Epub 2014 Jan 27.

PMID:
24320690
46.

Differential effects of thapsigargin analogues on apoptosis of prostate cancer cells: complex regulation by intracellular calcium.

Dubois C, Vanden Abeele F, Sehgal P, Olesen C, Junker S, Christensen SB, Prevarskaya N, Møller JV.

FEBS J. 2013 Nov;280(21):5430-40. doi: 10.1111/febs.12475. Epub 2013 Sep 2.

47.

Prevalence of polycystic ovary syndrome in adolescents.

Christensen SB, Black MH, Smith N, Martinez MM, Jacobsen SJ, Porter AH, Koebnick C.

Fertil Steril. 2013 Aug;100(2):470-7. doi: 10.1016/j.fertnstert.2013.04.001. Epub 2013 Jun 5.

48.

Water-mediated interactions influence the binding of thapsigargin to sarco/endoplasmic reticulum calcium adenosinetriphosphatase.

Paulsen ES, Villadsen J, Tenori E, Liu H, Bonde DF, Lie MA, Bublitz M, Olesen C, Autzen HE, Dach I, Sehgal P, Nissen P, Møller JV, Schiøtt B, Christensen SB.

J Med Chem. 2013 May 9;56(9):3609-19. doi: 10.1021/jm4001083. Epub 2013 Apr 30.

PMID:
23574308
49.

Alkaloid analysis by high-performance liquid chromatography-solid phase extraction-nuclear magnetic resonance: new strategies going beyond the standard.

Johansen KT, Ebild SJ, Christensen SB, Godejohann M, Jaroszewski JW.

J Chromatogr A. 2012 Dec 28;1270:171-7. doi: 10.1016/j.chroma.2012.10.072. Epub 2012 Nov 9.

PMID:
23195707
50.

Accuracy of the ICD-10 discharge diagnosis for syncope.

Ruwald MH, Hansen ML, Lamberts M, Kristensen SL, Wissenberg M, Olsen AM, Christensen SB, Vinther M, Køber L, Torp-Pedersen C, Hansen J, Gislason GH.

Europace. 2013 Apr;15(4):595-600. doi: 10.1093/europace/eus359. Epub 2012 Nov 4.

PMID:
23129545

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