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Longitudinal Study on Causes of Mortality in Danish Broiler Breeders.

Naundrup Thøfner IC, Poulsen LL, Bisgaard M, Christensen H, Olsen RH, Christensen JP.

Avian Dis. 2019 Sep 1;63(3):400-410. doi: 10.1637/12006-113018-Reg.1.


Infectious potential of human derived uropathogenic Escherichia coli UTI89 in the reproductive tract of laying hens.

Mortensen S, Johansen AE, Thøfner I, Christensen JP, Pors SE, Fresno AH, Møller-Jensen J, Olsen JE.

Vet Microbiol. 2019 Dec;239:108445. doi: 10.1016/j.vetmic.2019.108445. Epub 2019 Oct 4.


Comparison and assessment of necropsy lesions in end-of-lay laying hens from different housing systems in Denmark.

Wang C, Pors SE, Christensen JP, Bojesen AM, Thøfner I.

Poult Sci. 2019 Sep 24. pii: pez569. doi: 10.3382/ps/pez569. [Epub ahead of print]


Haematology, blood biochemistry, parasites and pathology of common eider (Somateria mollisima) males during a mortality event in the Baltic.

Garbus SE, Christensen JP, Buchmann K, Jessen TB, Lyngs P, Jacobsen ML, Garbus G, Lund E, Garbus PG, Madsen JJ, Thorup K, Sonne C.

Sci Total Environ. 2019 Sep 15;683:559-567. doi: 10.1016/j.scitotenv.2019.05.281. Epub 2019 May 21.


Correlation between footpad lesions and systemic bacterial infections in broiler breeders.

Thøfner ICN, Poulsen LL, Bisgaard M, Christensen H, Olsen RH, Christensen JP.

Vet Res. 2019 May 22;50(1):38. doi: 10.1186/s13567-019-0657-8.


Local Antigen Encounter Is Essential for Establishing Persistent CD8+ T-Cell Memory in the CNS.

Schøller AS, Fonnes M, Nazerai L, Christensen JP, Thomsen AR.

Front Immunol. 2019 Mar 4;10:351. doi: 10.3389/fimmu.2019.00351. eCollection 2019.


The SPI-19 encoded type-six secretion-systems (T6SS) of Salmonella enterica serovars Gallinarum and Dublin play different roles during infection.

Schroll C, Huang K, Ahmed S, Kristensen BM, Pors SE, Jelsbak L, Lemire S, Thomsen LE, Christensen JP, Jensen PR, Olsen JE.

Vet Microbiol. 2019 Mar;230:23-31. doi: 10.1016/j.vetmic.2019.01.006. Epub 2019 Jan 7.


Effects of changes in land use and climate on aquatic ecosystems: Coupling of models and decomposition of uncertainties.

Trolle D, Nielsen A, Andersen HE, Thodsen H, Olesen JE, Børgesen CD, Refsgaard JC, Sonnenborg TO, Karlsson IB, Christensen JP, Markager S, Jeppesen E.

Sci Total Environ. 2019 Mar 20;657:627-633. doi: 10.1016/j.scitotenv.2018.12.055. Epub 2018 Dec 5.


Chemokine Expression in Murine RPE/Choroid in Response to Systemic Viral Infection and Elevated Levels of Circulating Interferon-γ.

Faber C, Juel HB, Jensen BAH, Christensen JP, Prause JU, Thomsen AR, Nissen MH.

Invest Ophthalmol Vis Sci. 2019 Jan 2;60(1):192-201. doi: 10.1167/iovs.18-25721.


A Liposome-Based Adjuvant Containing Two Delivery Systems with the Ability to Induce Mucosal Immunoglobulin A Following a Parenteral Immunization.

Christensen D, Bøllehuus Hansen L, Leboux R, Jiskoot W, Christensen JP, Andersen P, Dietrich J.

ACS Nano. 2019 Feb 26;13(2):1116-1126. doi: 10.1021/acsnano.8b05209. Epub 2019 Jan 18.


Screening the ToxCast Phase 1, Phase 2, and e1k Chemical Libraries for Inhibitors of Iodothyronine Deiodinases.

Olker JH, Korte JJ, Denny JS, Hartig PC, Cardon MC, Knutsen CN, Kent PM, Christensen JP, Degitz SJ, Hornung MW.

Toxicol Sci. 2019 Apr 1;168(2):430-442. doi: 10.1093/toxsci/kfy302.


Single-cell heterogeneity in Sézary syndrome.

Buus TB, Willerslev-Olsen A, Fredholm S, Blümel E, Nastasi C, Gluud M, Hu T, Lindahl LM, Iversen L, Fogh H, Gniadecki R, Litvinov IV, Persson JL, Bonefeld CM, Geisler C, Christensen JP, Krejsgaard T, Litman T, Woetmann A, Ødum N.

Blood Adv. 2018 Aug 28;2(16):2115-2126. doi: 10.1182/bloodadvances.2018022608.


Analysis of adenovirus-induced immunity to infection with Listeria monocytogenes: Fading protection coincides with declining CD8 T cell numbers and phenotypic changes.

Jahn ML, Steffensen MA, Christensen JP, Thomsen AR.

Vaccine. 2018 May 11;36(20):2825-2832. doi: 10.1016/j.vaccine.2018.03.080. Epub 2018 Apr 5.


A New In Vivo Model to Study Protective Immunity to Zika Virus Infection in Mice With Intact Type I Interferon Signaling.

Nazerai L, Schøller AS, Rasmussen POS, Buus S, Stryhn A, Christensen JP, Thomsen AR.

Front Immunol. 2018 Mar 22;9:593. doi: 10.3389/fimmu.2018.00593. eCollection 2018.


Seasonal Influenza Split Vaccines Confer Partial Cross-Protection against Heterologous Influenza Virus in Ferrets When Combined with the CAF01 Adjuvant.

Christensen D, Christensen JP, Korsholm KS, Isling LK, Erneholm K, Thomsen AR, Andersen P.

Front Immunol. 2018 Jan 8;8:1928. doi: 10.3389/fimmu.2017.01928. eCollection 2017.


Staphylococcus agnetis, a potential pathogen in broiler breeders.

Poulsen LL, Thøfner I, Bisgaard M, Olsen RH, Christensen JP, Christensen H.

Vet Microbiol. 2017 Dec;212:1-6. doi: 10.1016/j.vetmic.2017.10.018. Epub 2017 Oct 28.


Treatment with high-dose antidepressants severely exacerbates the pathological outcome of experimental Escherichia coli infections in poultry.

Kromann S, Kudirkiene E, Li L, Thoefner I, Daldorph E, Christensen JP, Meng H, Olsen RH.

PLoS One. 2017 Oct 11;12(10):e0185914. doi: 10.1371/journal.pone.0185914. eCollection 2017.


Longitudinal study of transmission of Escherichia coli from broiler breeders to broilers.

Poulsen LL, Thøfner I, Bisgaard M, Christensen JP, Olsen RH, Christensen H.

Vet Microbiol. 2017 Aug;207:13-18. doi: 10.1016/j.vetmic.2017.05.029. Epub 2017 Jun 1.


Chromosomal features of Escherichia coli serotype O2:K2, an avian pathogenic E. coli.

Jørgensen SL, Kudirkiene E, Li L, Christensen JP, Olsen JE, Nolan L, Olsen RH.

Stand Genomic Sci. 2017 May 10;12:33. doi: 10.1186/s40793-017-0245-3. eCollection 2017.


Broadening CD4+ and CD8+ T Cell Responses against Hepatitis C Virus by Vaccination with NS3 Overlapping Peptide Panels in Cross-Priming Liposomes.

Filskov J, Mikkelsen M, Hansen PR, Christensen JP, Thomsen AR, Andersen P, Bukh J, Agger EM.

J Virol. 2017 Jun 26;91(14). pii: e00130-17. doi: 10.1128/JVI.00130-17. Print 2017 Jul 15.


Local Th17/IgA immunity correlate with protection against intranasal infection with Streptococcus pyogenes.

Mortensen R, Christensen D, Hansen LB, Christensen JP, Andersen P, Dietrich J.

PLoS One. 2017 Apr 17;12(4):e0175707. doi: 10.1371/journal.pone.0175707. eCollection 2017.


Adaptive immune responses to booster vaccination against yellow fever virus are much reduced compared to those after primary vaccination.

Kongsgaard M, Bassi MR, Rasmussen M, Skjødt K, Thybo S, Gabriel M, Hansen MB, Christensen JP, Thomsen AR, Buus S, Stryhn A.

Sci Rep. 2017 Apr 6;7(1):662. doi: 10.1038/s41598-017-00798-1.


Mucosal Vaccination with Heterologous Viral Vectored Vaccine Targeting Subdominant SIV Accessory Antigens Strongly Inhibits Early Viral Replication.

Xu H, Andersson AM, Ragonnaud E, Boilesen D, Tolver A, Jensen BAH, Blanchard JL, Nicosia A, Folgori A, Colloca S, Cortese R, Thomsen AR, Christensen JP, Veazey RS, Holst PJ.

EBioMedicine. 2017 Apr;18:204-215. doi: 10.1016/j.ebiom.2017.03.003. Epub 2017 Mar 8.


Inter-rater agreement in visual assessment of footpad dermatitis in Danish broiler chickens.

Oliveira ARS, Lund VP, Christensen JP, Nielsen LR.

Br Poult Sci. 2017 Jun;58(3):224-229. doi: 10.1080/00071668.2017.1293231. Epub 2017 Mar 15.


Evaluation of the Danish footpad lesion surveillance in conventional and organic broilers: Misclassification of scoring.

Lund VP, Nielsen LR, Oliveira ARS, Christensen JP.

Poult Sci. 2017 Jul 1;96(7):2018-2028. doi: 10.3382/ps/pex024.


Detection of local inflammation induced by repeated exposure to contact allergens by use of IVIS SpectrumCT analyses.

Nielsen MM, Schmidt JD, Christensen JP, Geisler C, Johansen JD, Bonefeld CM.

Contact Dermatitis. 2017 Apr;76(4):210-217. doi: 10.1111/cod.12746. Epub 2017 Jan 25.


EBI2 overexpression in mice leads to B1 B-cell expansion and chronic lymphocytic leukemia-like B-cell malignancies.

Niss Arfelt K, Barington L, Benned-Jensen T, Kubale V, Kovalchuk AL, Daugvilaite V, Christensen JP, Thomsen AR, Egerod KL, Bassi MR, Spiess K, Schwartz TW, Wang H, Morse HC 3rd, Holst PJ, Rosenkilde MM.

Blood. 2017 Feb 16;129(7):866-878. doi: 10.1182/blood-2016-02-697185. Epub 2016 Dec 21.


Evaluation of the efficacy of an autogenous Escherichia coli vaccine in broiler breeders.

Li L, Thøfner I, Christensen JP, Ronco T, Pedersen K, Olsen RH.

Avian Pathol. 2017 Jun;46(3):300-308. doi: 10.1080/03079457.2016.1267857. Epub 2017 Mar 20.


Early life vaccination: Generation of adult-quality memory CD8+ T cells in infant mice using non-replicating adenoviral vectors.

Nazerai L, Bassi MR, Uddback IE, Holst PJ, Christensen JP, Thomsen AR.

Sci Rep. 2016 Dec 8;6:38666. doi: 10.1038/srep38666.


PB1 as a potential target for increasing the breadth of T-cell mediated immunity to Influenza A.

Uddbäck IE, Steffensen MA, Pedersen SR, Nazerai L, Thomsen AR, Christensen JP.

Sci Rep. 2016 Oct 7;6:35033. doi: 10.1038/srep35033.


Effect of 12-O-tetradecanoylphorbol-13-acetate-induced psoriasis-like skin lesions on systemic inflammation and atherosclerosis in hypercholesterolaemic apolipoprotein E deficient mice.

Madsen M, Hansen PR, Nielsen LB, Hartvigsen K, Pedersen AE, Christensen JP, Aarup A, Pedersen TX.

BMC Dermatol. 2016 Jul 11;16(1):9. doi: 10.1186/s12895-016-0046-1.


Application of image cytometry to characterize heterologous lipid flippases in yeast.

Jensen MS, Costa SR, Theorin L, Christensen JP, Pomorski TG, López-Marqués RL.

Cytometry A. 2016 Jul;89(7):673-80. doi: 10.1002/cyto.a.22886. Epub 2016 Jun 6.


Experimental induced avian E. coli salpingitis: Significant impact of strain and host factors on the clinical and pathological outcome.

Olsen RH, Thøfner IC, Pors SE, Pires Dos Santos T, Christensen JP.

Vet Microbiol. 2016 May 30;188:59-66. doi: 10.1016/j.vetmic.2016.04.011. Epub 2016 Apr 11.


Pathology and Molecular Characterization of Escherichia Coli Associated With the Avian Salpingitis-Peritonitis Disease Syndrome.

Heidemann Olsen R, Bisgaard M, Christensen JP, Kabell S, Christensen H.

Avian Dis. 2016 Mar;60(1):1-7. doi: 10.1637/11237-071715-Reg.1.


Identifying protective Streptococcus pyogenes vaccine antigens recognized by both B and T cells in human adults and children.

Mortensen R, Nissen TN, Fredslund S, Rosenkrands I, Christensen JP, Andersen P, Dietrich J.

Sci Rep. 2016 Feb 25;6:22030. doi: 10.1038/srep22030.


Vaccination with Replication Deficient Adenovectors Encoding YF-17D Antigens Induces Long-Lasting Protection from Severe Yellow Fever Virus Infection in Mice.

Bassi MR, Larsen MA, Kongsgaard M, Rasmussen M, Buus S, Stryhn A, Thomsen AR, Christensen JP.

PLoS Negl Trop Dis. 2016 Feb 17;10(2):e0004464. doi: 10.1371/journal.pntd.0004464. eCollection 2016 Feb.


Vaccine Targeting of Subdominant CD8+ T Cell Epitopes Increases the Breadth of the T Cell Response upon Viral Challenge, but May Impair Immediate Virus Control.

Steffensen MA, Pedersen LH, Jahn ML, Nielsen KN, Christensen JP, Thomsen AR.

J Immunol. 2016 Mar 15;196(6):2666-76. doi: 10.4049/jimmunol.1502018. Epub 2016 Feb 12.


Combined local and systemic immunization is essential for durable T-cell mediated heterosubtypic immunity against influenza A virus.

Uddback IE, Pedersen LM, Pedersen SR, Steffensen MA, Holst PJ, Thomsen AR, Christensen JP.

Sci Rep. 2016 Feb 1;6:20137. doi: 10.1038/srep20137.


Immunogenicity of HLA Class I and II Double Restricted Influenza A-Derived Peptides.

Pedersen SR, Christensen JP, Buus S, Rasmussen M, Korsholm KS, Nielsen M, Claesson MH.

PLoS One. 2016 Jan 5;11(1):e0145629. doi: 10.1371/journal.pone.0145629. eCollection 2016.


Draft Genome Sequences of Two Commensal Enterococcus cecorum Strains Isolated from Chickens in Belgium.

Dolka B, Boyen F, Butaye P, Heidemann Olsen R, Naundrup Thøfner IC, Christensen JP.

Genome Announc. 2015 Sep 24;3(5). pii: e01108-15. doi: 10.1128/genomeA.01108-15.


Draft Genome Sequences of Five Clinical Enterococcus cecorum Strains Isolated from Different Poultry Species in Poland.

Dolka B, Heidemann Olsen R, Naundrup Thøfner IC, Christensen JP.

Genome Announc. 2015 Sep 17;3(5). pii: e01082-15. doi: 10.1128/genomeA.01082-15.


[HPV vaccination – should/should not?].

Thomsen AR, Christensen JP.

Ugeskr Laeger. 2015 Aug 31;177(18). pii: V67374. Danish. No abstract available.


Adaptive Immunity against Streptococcus pyogenes in Adults Involves Increased IFN-γ and IgG3 Responses Compared with Children.

Mortensen R, Nissen TN, Blauenfeldt T, Christensen JP, Andersen P, Dietrich J.

J Immunol. 2015 Aug 15;195(4):1657-64. doi: 10.4049/jimmunol.1500804. Epub 2015 Jul 10.


Draft Genome Sequences of Three Escherichia coli Strains with Different In Vivo Pathogenicities in an Avian (Ascending) Infection Model of the Oviduct.

Olsen RH, Thøfner IC, Pors SE, Christensen H, Bisgaard M, Christensen JP.

Genome Announc. 2015 May 7;3(3). pii: e00399-15. doi: 10.1128/genomeA.00399-15.


Protein energy malnutrition during vaccination has limited influence on vaccine efficacy but abolishes immunity if administered during Mycobacterium tuberculosis infection.

Hoang T, Agger EM, Cassidy JP, Christensen JP, Andersen P.

Infect Immun. 2015 May;83(5):2118-26. doi: 10.1128/IAI.03030-14. Epub 2015 Mar 9.


Targeting of non-dominant antigens as a vaccine strategy to broaden T-cell responses during chronic viral infection.

Holst PJ, Jensen BA, Ragonnaud E, Thomsen AR, Christensen JP.

PLoS One. 2015 Feb 13;10(2):e0117242. doi: 10.1371/journal.pone.0117242. eCollection 2015.


CD8+ T cells complement antibodies in protecting against yellow fever virus.

Bassi MR, Kongsgaard M, Steffensen MA, Fenger C, Rasmussen M, Skjødt K, Finsen B, Stryhn A, Buus S, Christensen JP, Thomsen AR.

J Immunol. 2015 Feb 1;194(3):1141-53. doi: 10.4049/jimmunol.1402605. Epub 2014 Dec 24.


Suppressors of cytokine signaling 1 and 3 are upregulated in brain resident cells in response to virus-induced inflammation of the central nervous system via at least two distinctive pathways.

Steffensen MA, Fenger C, Christensen JE, Jørgensen CK, Bassi MR, Christensen JP, Finsen B, Thomsen AR.

J Virol. 2014 Dec;88(24):14090-104. doi: 10.1128/JVI.01346-14. Epub 2014 Sep 24.


Co-expression of tumor antigen and interleukin-2 from an adenoviral vector augments the efficiency of therapeutic tumor vaccination.

Jensen BA, Steffensen MA, Nielsen KN, Christensen JP, Thomsen AR, Holst PJ.

Mol Ther. 2014 Dec;22(12):2107-17. doi: 10.1038/mt.2014.130. Epub 2014 Jul 15.


Inflammation-induced haemostatic response in layer chickens infected with Streptococcus equi subsp. zooepidemicus as evaluated by fibrinogen, prothrombin time and thromboelastography.

Roy K, Bertelsen MF, Pors SE, Johansen KW, Kristensen AT, Kjelgaard-Hansen M, Andreasen EB, Christensen JP, Biswas PK, Bojesen AM.

Avian Pathol. 2014;43(4):364-70. doi: 10.1080/03079457.2014.938608. Epub 2014 Jul 21.


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