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Items: 1 to 50 of 127

1.

Chemical Approach to Biological Safety: Molecular-Level Control of an Integrated Zinc Finger Nuclease.

Németh E, Asaka MN, Kato K, Fábián Z, Oostenbrink C, Christensen HEM, Nagata K, Gyurcsik B.

Chembiochem. 2018 Jan 4;19(1):66-75. doi: 10.1002/cbic.201700420. Epub 2017 Dec 12.

PMID:
29077265
2.

Isoform-Specific Substrate Inhibition Mechanism of Human Tryptophan Hydroxylase.

Tidemand KD, Peters GH, Harris P, Stensgaard E, Christensen HEM.

Biochemistry. 2017 Nov 21;56(46):6155-6164. doi: 10.1021/acs.biochem.7b00763. Epub 2017 Oct 27.

PMID:
29035515
3.

Extracellular polymeric substances are transient media for microbial extracellular electron transfer.

Xiao Y, Zhang E, Zhang J, Dai Y, Yang Z, Christensen HEM, Ulstrup J, Zhao F.

Sci Adv. 2017 Jul 5;3(7):e1700623. doi: 10.1126/sciadv.1700623. eCollection 2017 Jul.

4.

Stabilization of tryptophan hydroxylase 2 by l-phenylalanine-induced dimerization.

Tidemand KD, Christensen HE, Hoeck N, Harris P, Boesen J, Peters GH.

FEBS Open Bio. 2016 Aug 22;6(10):987-999. eCollection 2016 Oct.

5.

Muscle power is an important measure to detect deficits in muscle function in hip osteoarthritis: a cross-sectional study.

Bieler T, Magnusson SP, Christensen HE, Kjaer M, Beyer N.

Disabil Rehabil. 2017 Jul;39(14):1414-1421. doi: 10.1080/09638288.2016.1198426. Epub 2016 Jul 3.

PMID:
27374992
6.

The crystal structure of human dopamine β-hydroxylase at 2.9 Å resolution.

Vendelboe TV, Harris P, Zhao Y, Walter TS, Harlos K, El Omari K, Christensen HE.

Sci Adv. 2016 Apr 8;2(4):e1500980. doi: 10.1126/sciadv.1500980. eCollection 2016 Apr.

7.

In hip osteoarthritis, Nordic Walking is superior to strength training and home-based exercise for improving function.

Bieler T, Siersma V, Magnusson SP, Kjaer M, Christensen HE, Beyer N.

Scand J Med Sci Sports. 2017 Aug;27(8):873-886. doi: 10.1111/sms.12694. Epub 2016 Apr 30.

PMID:
27129607
8.

Advanced purification strategy for CueR, a cysteine containing copper(I) and DNA binding protein.

Balogh RK, Gyurcsik B, Hunyadi-Gulyás É, Christensen HE, Jancsó A.

Protein Expr Purif. 2016 Jul;123:90-6. doi: 10.1016/j.pep.2016.03.012. Epub 2016 Mar 30.

PMID:
27038857
9.

An efficient arabinoxylan-debranching α-L-arabinofuranosidase of family GH62 from Aspergillus nidulans contains a secondary carbohydrate binding site.

Wilkens C, Andersen S, Petersen BO, Li A, Busse-Wicher M, Birch J, Cockburn D, Nakai H, Christensen HE, Kragelund BB, Dupree P, McCleary B, Hindsgaul O, Hachem MA, Svensson B.

Appl Microbiol Biotechnol. 2016 Jul;100(14):6265-77. doi: 10.1007/s00253-016-7417-8. Epub 2016 Mar 5.

PMID:
26946172
10.

A new insight into the zinc-dependent DNA-cleavage by the colicin E7 nuclease: a crystallographic and computational study.

Czene A, Tóth E, Németh E, Otten H, Poulsen JC, Christensen HE, Rulíšek L, Nagata K, Larsen S, Gyurcsik B.

Metallomics. 2014 Nov;6(11):2090-9. doi: 10.1039/c4mt00195h.

PMID:
25179124
11.

Substrate binding activates the designed triple mutant of the colicin E7 metallonuclease.

Németh E, Körtvélyesi T, Kožíšek M, Thulstrup PW, Christensen HE, Asaka MN, Nagata K, Gyurcsik B.

J Biol Inorg Chem. 2014 Dec;19(8):1295-303. doi: 10.1007/s00775-014-1186-6. Epub 2014 Aug 26.

PMID:
25156149
12.

Fine tuning of the catalytic activity of colicin E7 nuclease domain by systematic N-terminal mutations.

Németh E, Körtvélyesi T, Thulstrup PW, Christensen HE, Kožíšek M, Nagata K, Czene A, Gyurcsik B.

Protein Sci. 2014 Aug;23(8):1113-22. doi: 10.1002/pro.2497. Epub 2014 Jun 17.

13.

The antimalarial drug quinine interferes with serotonin biosynthesis and action.

Islahudin F, Tindall SM, Mellor IR, Swift K, Christensen HE, Fone KC, Pleass RJ, Ting KN, Avery SV.

Sci Rep. 2014 Jan 9;4:3618. doi: 10.1038/srep03618.

14.

Crystallization and preliminary crystallographic analysis of an Escherichia coli-selected mutant of the nuclease domain of the metallonuclease colicin E7.

Czene A, Tóth E, Gyurcsik B, Otten H, Poulsen JC, Lo Leggio L, Larsen S, Christensen HE, Nagata K.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 May 1;69(Pt 5):551-4. doi: 10.1107/S1744309113008233. Epub 2013 Apr 30.

15.

The role of the N-terminal loop in the function of the colicin E7 nuclease domain.

Czene A, Németh E, Zóka IG, Jakab-Simon NI, Körtvélyesi T, Nagata K, Christensen HE, Gyurcsik B.

J Biol Inorg Chem. 2013 Mar;18(3):309-21. doi: 10.1007/s00775-013-0975-7. Epub 2013 Jan 19.

PMID:
23334162
16.

Heterometallic [AgFe(3)S (4)] ferredoxin variants: synthesis, characterization, and the first crystal structure of an engineered heterometallic iron-sulfur protein.

Martic M, Jakab-Simon IN, Haahr LT, Hagen WR, Christensen HE.

J Biol Inorg Chem. 2013 Feb;18(2):261-76. doi: 10.1007/s00775-012-0971-3. Epub 2013 Jan 8.

PMID:
23296387
17.

Inactivation of barley limit dextrinase inhibitor by thioredoxin-catalysed disulfide reduction.

Jensen JM, Hägglund P, Christensen HE, Svensson B.

FEBS Lett. 2012 Jul 30;586(16):2479-82. doi: 10.1016/j.febslet.2012.06.009. Epub 2012 Jun 19.

18.

Electrochemical single-molecule AFM of the redox metalloenzyme copper nitrite reductase in action.

Hao X, Zhang J, Christensen HE, Wang H, Ulstrup J.

Chemphyschem. 2012 Aug 27;13(12):2919-24. doi: 10.1002/cphc.201200220. Epub 2012 Jun 13.

PMID:
22696401
19.

Efficient secretory expression of functional barley limit dextrinase inhibitor by high cell-density fermentation of Pichia pastoris.

Jensen JM, Vester-Christensen MB, Møller MS, Bønsager BC, Christensen HE, Hachem MA, Svensson B.

Protein Expr Purif. 2011 Oct;79(2):217-22. doi: 10.1016/j.pep.2011.04.009. Epub 2011 Apr 27.

PMID:
21539920
20.

Crystal structures of the all-cysteinyl-coordinated D14C variant of Pyrococcus furiosus ferredoxin: [4Fe-4S] ↔ [3Fe-4S] cluster conversion.

Løvgreen MN, Martic M, Windahl MS, Christensen HE, Harris P.

J Biol Inorg Chem. 2011 Jun;16(5):763-75. doi: 10.1007/s00775-011-0778-7. Epub 2011 Apr 12.

PMID:
21484348
21.

Pain and knee function in relation to degree of bone bruise after acute anterior cruciate ligament rupture.

Szkopek K, Warming T, Neergaard K, Jørgensen HL, Christensen HE, Krogsgaard M.

Scand J Med Sci Sports. 2012 Oct;22(5):635-42. doi: 10.1111/j.1600-0838.2011.01297.x. Epub 2011 Apr 8.

PMID:
21477165
22.

Moderate loading of the human osteoarthritic knee joint leads to lowering of intraarticular cartilage oligomeric matrix protein.

Helmark IC, Petersen MC, Christensen HE, Kjaer M, Langberg H.

Rheumatol Int. 2012 Apr;32(4):1009-14. doi: 10.1007/s00296-010-1716-7. Epub 2011 Jan 19.

PMID:
21246372
23.

Approach to interfacial and intramolecular electron transfer of the diheme protein cytochrome c4 assembled on Au(111) surfaces.

Chi Q, Zhang J, Arslan T, Borg L, Pedersen GW, Christensen HE, Nazmudtinov RR, Ulstrup J.

J Phys Chem B. 2010 Apr 29;114(16):5617-24. doi: 10.1021/jp1007208.

PMID:
20359200
24.

Experimentally calibrated computational chemistry of tryptophan hydroxylase: trans influence, hydrogen-bonding, and 18-electron rule govern O2-activation.

Haahr LT, Jensen KP, Boesen J, Christensen HE.

J Inorg Biochem. 2010 Feb;104(2):136-45. doi: 10.1016/j.jinorgbio.2009.10.010. Epub 2009 Oct 23.

PMID:
19939457
25.

Expression, purification and enzymatic characterization of the catalytic domains of human tryptophan hydroxylase isoforms.

Windahl MS, Boesen J, Karlsen PE, Christensen HE.

Protein J. 2009 Dec;28(9-10):400-6. doi: 10.1007/s10930-009-9207-y.

PMID:
19816759
26.

Histidine side-chain dynamics and protonation monitored by 13C CPMG NMR relaxation dispersion.

Hass MA, Yilmaz A, Christensen HE, Led JJ.

J Biomol NMR. 2009 Aug;44(4):225-33. doi: 10.1007/s10858-009-9332-0. Epub 2009 Jun 17.

PMID:
19533375
27.

Electron transfer patterns of the di-heme protein cytochrome c(4) from Pseudomonas stutzeri.

Raffalt AC, Schmidt L, Christensen HE, Chi Q, Ulstrup J.

J Inorg Biochem. 2009 May;103(5):717-22. doi: 10.1016/j.jinorgbio.2009.01.004. Epub 2009 Jan 21.

PMID:
19217165
28.

Crystal structure of tryptophan hydroxylase with bound amino acid substrate.

Windahl MS, Petersen CR, Christensen HE, Harris P.

Biochemistry. 2008 Nov 18;47(46):12087-94. doi: 10.1021/bi8015263. Epub 2008 Oct 21.

PMID:
18937498
29.

Computational chemistry of modified [MFe3S4] and [M2Fe2S4] clusters: assessment of trends in electronic structure and properties.

Jensen KP, Ooi BL, Christensen HE.

J Phys Chem A. 2008 Dec 18;112(50):12829-41. doi: 10.1021/jp8014782.

PMID:
18610989
30.

Characterization of conformational exchange of a histidine side chain: protonation, rotamerization, and tautomerization of His61 in plastocyanin from Anabaena variabilis.

Hass MA, Hansen DF, Christensen HE, Led JJ, Kay LE.

J Am Chem Soc. 2008 Jul 2;130(26):8460-70. doi: 10.1021/ja801330h. Epub 2008 Jun 7.

PMID:
18540585
31.

Weak self-association of human growth hormone investigated by nitrogen-15 NMR relaxation.

Jensen MR, Kristensen SM, Keeler C, Christensen HE, Hodsdon ME, Led JJ.

Proteins. 2008 Oct;73(1):161-72. doi: 10.1002/prot.22039.

PMID:
18409193
32.

A simple two step procedure for purification of the catalytic domain of chicken tryptophan hydroxylase 1 in a form suitable for crystallization.

Nielsen MS, Petersen CR, Munch A, Vendelboe TV, Boesen J, Harris P, Christensen HE.

Protein Expr Purif. 2008 Feb;57(2):116-26. Epub 2007 Nov 20.

PMID:
18055219
33.

Kinetics and mechanism of the acid transition of the active site in plastocyanin.

Hass MA, Christensen HE, Zhang J, Led JJ.

Biochemistry. 2007 Dec 18;46(50):14619-28. Epub 2007 Nov 17.

PMID:
18020375
34.

Accurate computation of reduction potentials of 4Fe-4S clusters indicates a carboxylate shift in Pyrococcus furiosus ferredoxin.

Jensen KP, Ooi BL, Christensen HE.

Inorg Chem. 2007 Oct 15;46(21):8710-6. Epub 2007 Sep 19.

PMID:
17880061
35.

Structure of plastocyanin from the cyanobacterium Anabaena variabilis.

Schmidt L, Christensen HE, Harris P.

Acta Crystallogr D Biol Crystallogr. 2006 Sep;62(Pt 9):1022-9. Epub 2006 Aug 19.

PMID:
16929103
36.

Long-range interfacial electron transfer of metalloproteins based on molecular wiring assemblies.

Chi Q, Zhang J, Jensen PS, Christensen HE, Ulstrup J.

Faraday Discuss. 2006;131:181-95; discussion 205-20.

PMID:
16512372
37.

On the use of pseudocontact shifts in the structure determination of metalloproteins.

Jensen MR, Hansen DF, Ayna U, Dagil R, Hass MA, Christensen HE, Led JJ.

Magn Reson Chem. 2006 Mar;44(3):294-301.

PMID:
16477687
38.

Reinvestigation of the method used to map the electronic structure of blue copper proteins by NMR relaxation.

Flemming Hansen D, Gorelsky SI, Sarangi R, Hodgson KO, Hedman B, Christensen HE, Solomon EI, Led JJ.

J Biol Inorg Chem. 2006 Apr;11(3):277-85. Epub 2006 Jan 24.

PMID:
16432723
39.
40.

The 1.5 A resolution crystal structure of [Fe3S4]-ferredoxin from the hyperthermophilic archaeon Pyrococcus furiosus.

Nielsen MS, Harris P, Ooi BL, Christensen HE.

Biochemistry. 2004 May 11;43(18):5188-94.

PMID:
15122884
41.

Cytoplasmic expression of the Achromobacter xylosoxidans blue copper nitrite reductase in Escherichia coli and characterisation of the recombinant protein.

Ho WH, Ooi BL, Jørgensen AM, Borg L, Jespersen LL, Christensen HE.

Protein Expr Purif. 2003 Dec;32(2):288-92.

PMID:
14965775
43.

Crystallization of [Fe3S4]-ferredoxin from the hyperthermophile archaeon Pyrococcus furiosus.

Nielsen MS, Harris P, Christensen HE.

Acta Crystallogr D Biol Crystallogr. 2003 Dec;59(Pt 12):2325-7. Epub 2003 Nov 27.

PMID:
14646109
44.

Expression of recombinant Pseudomonas stutzeri di-heme cytochrome c4 by high-cell-density fed-batch cultivation of Pseudomonas putida.

Thuesen MH, Nørgaard A, Hansen AM, Caspersen MB, Christensen HE.

Protein Expr Purif. 2003 Jan;27(1):175-81.

PMID:
12510001
45.

Profilin plays a role in cell elongation, cell shape maintenance, and flowering in Arabidopsis.

Ramachandran S, Christensen HE, Ishimaru Y, Dong CH, Chao-Ming W, Cleary AL, Chua NH.

Plant Physiol. 2000 Dec;124(4):1637-47.

46.

Expression and characterization of recombinant Rhodocyclus tenuis high potential iron-sulfur protein.

Caspersen MB, Bennett K, Christensen HE.

Protein Expr Purif. 2000 Jul;19(2):259-64.

PMID:
10873539
47.

The crystal structure of a major allergen from plants.

Thorn KS, Christensen HE, Shigeta R, Huddler D, Shalaby L, Lindberg U, Chua NH, Schutt CE.

Structure. 1997 Jan 15;5(1):19-32.

48.
49.

Total synthesis of a miniferredoxin.

Sow TC, Pederson MV, Christensen HE, Ooi BL.

Biochem Biophys Res Commun. 1996 Jun 14;223(2):360-4.

PMID:
8670287
50.

Synthesis and characterization of Desulfovibrio gigas rubredoxin and rubredoxin fragments.

Christensen HE, Hammerstad-Pedersen JM, Holm A, Iversen G, Jensen MH, Ulstrup J.

Eur J Biochem. 1994 Aug 15;224(1):97-101.

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