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Items: 34

1.

Post-translational regulation could be determine functional differences between SET alpha and beta isoform - Response to Cristóbal et al.

Weinberg JB, Brander DM, Christensen DJ, Friedman DR.

Br J Haematol. 2019 Aug;186(4):637. doi: 10.1111/bjh.15934. Epub 2019 May 1. No abstract available.

PMID:
31044417
2.

SET alpha and SET beta mRNA isoforms in chronic lymphocytic leukaemia.

Brander DM, Friedman DR, Volkheimer AD, Christensen DJ, Rassenti LZ, Kipps TJ, Guadalupe E, Chen Y, Zhang D, Wang X, Davis C, Owzar K, Weinberg JB.

Br J Haematol. 2019 Feb;184(4):605-615. doi: 10.1111/bjh.15677. Epub 2018 Nov 15.

PMID:
30443898
3.

Activation of PP2A and Inhibition of mTOR Synergistically Reduce MYC Signaling and Decrease Tumor Growth in Pancreatic Ductal Adenocarcinoma.

Allen-Petersen BL, Risom T, Feng Z, Wang Z, Jenny ZP, Thoma MC, Pelz KR, Morton JP, Sansom OJ, Lopez CD, Sheppard B, Christensen DJ, Ohlmeyer M, Narla G, Sears RC.

Cancer Res. 2019 Jan 1;79(1):209-219. doi: 10.1158/0008-5472.CAN-18-0717. Epub 2018 Nov 2.

PMID:
30389701
4.

SPX-101 Is a Novel Epithelial Sodium Channel-targeted Therapeutic for Cystic Fibrosis That Restores Mucus Transport.

Scott DW, Walker MP, Sesma J, Wu B, Stuhlmiller TJ, Sabater JR, Abraham WM, Crowder TM, Christensen DJ, Tarran R.

Am J Respir Crit Care Med. 2017 Sep 15;196(6):734-744. doi: 10.1164/rccm.201612-2445OC.

PMID:
28481660
5.

Combined targeting of SET and tyrosine kinases provides an effective therapeutic approach in human T-cell acute lymphoblastic leukemia.

Richard NP, Pippa R, Cleary MM, Puri A, Tibbitts D, Mahmood S, Christensen DJ, Jeng S, McWeeney S, Look AT, Chang BH, Tyner JW, Vitek MP, Odero MD, Sears R, Agarwal A.

Oncotarget. 2016 Dec 20;7(51):84214-84227. doi: 10.18632/oncotarget.12394.

6.

Targeting c-MYC by antagonizing PP2A inhibitors in breast cancer.

Janghorban M, Farrell AS, Allen-Petersen BL, Pelz C, Daniel CJ, Oddo J, Langer EM, Christensen DJ, Sears RC.

Proc Natl Acad Sci U S A. 2014 Jun 24;111(25):9157-62. doi: 10.1073/pnas.1317630111. Epub 2014 Jun 9.

7.

Effect of FTY720 on the SET-PP2A complex in acute myeloid leukemia; SET binding drugs have antagonistic activity.

Pippa R, Dominguez A, Christensen DJ, Moreno-Miralles I, Blanco-Prieto MJ, Vitek MP, Odero MD.

Leukemia. 2014 Sep;28(9):1915-8. doi: 10.1038/leu.2014.141. Epub 2014 Apr 30. No abstract available.

PMID:
24781014
8.

Targeting inhibitors of the tumor suppressor PP2A for the treatment of pancreatic cancer.

Farrell AS, Allen-Petersen B, Daniel CJ, Wang X, Wang Z, Rodriguez S, Impey S, Oddo J, Vitek MP, Lopez C, Christensen DJ, Sheppard B, Sears RC.

Mol Cancer Res. 2014 Jun;12(6):924-39. doi: 10.1158/1541-7786.MCR-13-0542. Epub 2014 Mar 25.

9.

Antagonism of SET using OP449 enhances the efficacy of tyrosine kinase inhibitors and overcomes drug resistance in myeloid leukemia.

Agarwal A, MacKenzie RJ, Pippa R, Eide CA, Oddo J, Tyner JW, Sears R, Vitek MP, Odero MD, Christensen DJ, Druker BJ.

Clin Cancer Res. 2014 Apr 15;20(8):2092-103. doi: 10.1158/1078-0432.CCR-13-2575. Epub 2014 Jan 16.

10.

Sleep drives metabolite clearance from the adult brain.

Xie L, Kang H, Xu Q, Chen MJ, Liao Y, Thiyagarajan M, O'Donnell J, Christensen DJ, Nicholson C, Iliff JJ, Takano T, Deane R, Nedergaard M.

Science. 2013 Oct 18;342(6156):373-7. doi: 10.1126/science.1241224.

11.

Gelatinases impart susceptibility to high-fat diet-induced obesity in mice.

Biga PR, Froehlich JM, Greenlee KJ, Galt NJ, Meyer BM, Christensen DJ.

J Nutr Biochem. 2013 Aug;24(8):1462-8. doi: 10.1016/j.jnutbio.2012.12.005. Epub 2013 Mar 1.

12.

A potential therapeutic application of SET/I2PP2A inhibitor OP449 for canine T-cell lymphoma.

Fujiwara N, Kawasaki H, Yabe R, Christensen DJ, Vitek MP, Mizuno T, Sato K, Ohama T.

J Vet Med Sci. 2013;75(3):349-54. Epub 2012 Nov 5.

13.

APOE-mimetic peptides reduce behavioral deficits, plaques and tangles in Alzheimer's disease transgenics.

Vitek MP, Christensen DJ, Wilcock D, Davis J, Van Nostrand WE, Li FQ, Colton CA.

Neurodegener Dis. 2012;10(1-4):122-6. doi: 10.1159/000334914. Epub 2012 Feb 9.

14.

The apoE-mimetic peptide, COG1410, improves functional recovery in a murine model of intracerebral hemorrhage.

Laskowitz DT, Lei B, Dawson HN, Wang H, Bellows ST, Christensen DJ, Vitek MP, James ML.

Neurocrit Care. 2012 Apr;16(2):316-26. doi: 10.1007/s12028-011-9641-5.

PMID:
21989844
15.

SET oncoprotein overexpression in B-cell chronic lymphocytic leukemia and non-Hodgkin lymphoma: a predictor of aggressive disease and a new treatment target.

Christensen DJ, Chen Y, Oddo J, Matta KM, Neil J, Davis ED, Volkheimer AD, Lanasa MC, Friedman DR, Goodman BK, Gockerman JP, Diehl LF, de Castro CM, Moore JO, Vitek MP, Weinberg JB.

Blood. 2011 Oct 13;118(15):4150-8. doi: 10.1182/blood-2011-04-351072. Epub 2011 Aug 15.

16.

Two-photon in vivo imaging of cells.

Christensen DJ, Nedergaard M.

Pediatr Nephrol. 2011 Sep;26(9):1483-9. doi: 10.1007/s00467-011-1818-9. Epub 2011 Mar 15. Review.

PMID:
21404099
17.

Targeting SET/I(2)PP2A oncoprotein functions as a multi-pathway strategy for cancer therapy.

Switzer CH, Cheng RY, Vitek TM, Christensen DJ, Wink DA, Vitek MP.

Oncogene. 2011 Jun 2;30(22):2504-13. doi: 10.1038/onc.2010.622. Epub 2011 Feb 7.

18.

Apolipoprotein E and peptide mimetics modulate inflammation by binding the SET protein and activating protein phosphatase 2A.

Christensen DJ, Ohkubo N, Oddo J, Van Kanegan MJ, Neil J, Li F, Colton CA, Vitek MP.

J Immunol. 2011 Feb 15;186(4):2535-42. doi: 10.4049/jimmunol.1002847.

19.

APOE genotype affects outcome in a murine model of sepsis: implications for a new treatment strategy.

Wang H, Christensen DJ, Vitek MP, Sullivan PM, Laskowitz DT.

Anaesth Intensive Care. 2009 Jan;37(1):38-45.

20.

Intracellular expression of Peptide fusions for demonstration of protein essentiality in bacteria.

Benson RE, Gottlin EB, Christensen DJ, Hamilton PT.

Antimicrob Agents Chemother. 2003 Sep;47(9):2875-81.

21.

High-throughput screen for inhibitors of 1-deoxy-d-xylulose 5-phosphate reductoisomerase by surrogate ligand competition.

Gottlin EB, Benson RE, Conary S, Antonio B, Duke K, Payne ES, Ashraf SS, Christensen DJ.

J Biomol Screen. 2003 Jun;8(3):332-9.

PMID:
12857387
22.

Phage display for target-based antibacterial drug discovery.

Christensen DJ, Gottlin EB, Benson RE, Hamilton PT.

Drug Discov Today. 2001 Jul 1;6(14):721-727.

PMID:
11445463
23.

Detection of small-molecule enzyme inhibitors with peptides isolated from phage-displayed combinatorial peptide libraries.

Hyde-DeRuyscher R, Paige LA, Christensen DJ, Hyde-DeRuyscher N, Lim A, Fredericks ZL, Kranz J, Gallant P, Zhang J, Rocklage SM, Fowlkes DM, Wendler PA, Hamilton PT.

Chem Biol. 2000 Jan;7(1):17-25.

24.

Comparative analyses of mechanistic differences among antiestrogens.

Wijayaratne AL, Nagel SC, Paige LA, Christensen DJ, Norris JD, Fowlkes DM, McDonnell DP.

Endocrinology. 1999 Dec;140(12):5828-40.

PMID:
10579349
25.

Peptide antagonists of the human estrogen receptor.

Norris JD, Paige LA, Christensen DJ, Chang CY, Huacani MR, Fan D, Hamilton PT, Fowlkes DM, McDonnell DP.

Science. 1999 Jul 30;285(5428):744-6.

26.

Estrogen receptor (ER) modulators each induce distinct conformational changes in ER alpha and ER beta.

Paige LA, Christensen DJ, Grøn H, Norris JD, Gottlin EB, Padilla KM, Chang CY, Ballas LM, Hamilton PT, McDonnell DP, Fowlkes DM.

Proc Natl Acad Sci U S A. 1999 Mar 30;96(7):3999-4004.

27.

Enzymatic synthesis of isotopically labeled isoprenoid diphosphates.

Christensen DJ, Poulter CD.

Bioorg Med Chem. 1994 Jul;2(7):631-7.

PMID:
7858969
28.

Isopentenyl-diphosphate isomerase: irreversible inhibition by 3-methyl-3,4-epoxybutyl diphosphate.

Lu XJ, Christensen DJ, Poulter CD.

Biochemistry. 1992 Oct 20;31(41):9955-60.

PMID:
1390779
29.

Differentiation of iron deficiency and the anemia of chronic disease.

Christensen DJ.

J Fam Pract. 1985 Jan;20(1):35-9.

PMID:
3965599
30.

Agranulocytosis, thrombocytopenia, and procainamide.

Christensen DJ, Palma LF, Phelps K.

Ann Intern Med. 1984 Jun;100(6):918. No abstract available.

PMID:
6721310
31.

Family medicine: reassessment of two educational objectives.

Christensen DJ.

J Med Educ. 1983 Jul;58(7):587-9. No abstract available.

PMID:
6864750
32.

Diagnosis of anemia. Clues to greater precision.

Christensen DJ.

Postgrad Med. 1983 Jan;73(1):293-7, 300.

PMID:
6848993
33.

Effect of hypertension on myocardial rupture after acute myocardial infarction.

Christensen DJ, Ford M, Reading J, Castle CH.

Chest. 1977 Nov;72(5):618-22.

PMID:
913141
34.

Epizootic neoplasms in the clam Macoma balthica (L.) from Chesapeake Bay.

Christensen DJ, Farley CA, Kern FG.

J Natl Cancer Inst. 1974 Jun;52(6):1739-49. No abstract available.

PMID:
4834406

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