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Items: 1 to 50 of 332

1.

Virtual supersampling as post-processing step preserves the trabecular bone morphometry in human peripheral quantitative computed tomography scans.

Schulte FA, Christen P, Badilatti SD, Parkinson I, Khosla S, Goldhahn J, Müller R.

PLoS One. 2019 Feb 13;14(2):e0212280. doi: 10.1371/journal.pone.0212280. eCollection 2019.

2.

Anti-inflammatory and Quinone Reductase-Inducing Compounds from Beilschmiedia mannii.

Ahoua ARC, Monteillier A, Borlat F, Ciclet O, Marcourt L, Nejad Ebrahimi S, Koné MW, Bonfoh B, Christen P, Cuendet M.

Planta Med. 2019 Mar;85(5):379-384. doi: 10.1055/a-0798-3155. Epub 2018 Nov 22.

PMID:
30466132
3.

Bioactive metabolites from the leaves of Withania adpressa.

Ben Bakrim W, El Bouzidi L, Nuzillard JM, Cretton S, Saraux N, Monteillier A, Christen P, Cuendet M, Bekkouche K.

Pharm Biol. 2018 Dec;56(1):505-510. doi: 10.1080/13880209.2018.1499781.

4.

Anti-inflammatory and antiproliferative diterpenoids from Plectranthus scutellarioides.

Cretton S, Saraux N, Monteillier A, Righi D, Marcourt L, Genta-Jouve G, Wolfender JL, Cuendet M, Christen P.

Phytochemistry. 2018 Oct;154:39-46. doi: 10.1016/j.phytochem.2018.06.012. Epub 2018 Jun 28.

PMID:
29960256
5.

Moving beyond the genome with computer modeling.

Christen P.

Per Med. 2018 May 1;15(3):145-148. doi: 10.2217/pme-2017-0066. Epub 2018 May 16. No abstract available.

PMID:
29767551
6.

Least-detectable and age-related local in vivo bone remodelling assessed by time-lapse HR-pQCT.

Christen P, Boutroy S, Ellouz R, Chapurlat R, van Rietbergen B.

PLoS One. 2018 Jan 24;13(1):e0191369. doi: 10.1371/journal.pone.0191369. eCollection 2018.

7.

Towards a 'smart' cost-benefit tool: using machine learning to predict the costs of criminal justice policy interventions.

Manning M, Wong GTW, Graham T, Ranbaduge T, Christen P, Taylor K, Wortley R, Makkai T, Skorich P.

Crime Sci. 2018;7(1):12. doi: 10.1186/s40163-018-0086-4. Epub 2018 Oct 12.

8.

Targeted Isolation of Monoterpene Indole Alkaloids from Palicourea sessilis.

Klein-Júnior LC, Cretton S, Allard PM, Genta-Jouve G, Passos CS, Salton J, Bertelli P, Pupier M, Jeannerat D, Heyden YV, Gasper AL, Wolfender JL, Christen P, Henriques AT.

J Nat Prod. 2017 Nov 22;80(11):3032-3037. doi: 10.1021/acs.jnatprod.7b00681. Epub 2017 Nov 9.

PMID:
29120642
9.

Misfolding and aggregation of nascent proteins: a novel mode of toxic cadmium action in vivo.

Tamás MJ, Fauvet B, Christen P, Goloubinoff P.

Curr Genet. 2018 Feb;64(1):177-181. doi: 10.1007/s00294-017-0748-x. Epub 2017 Sep 21. Review.

10.

Patient-specific in silico models can quantify primary implant stability in elderly human bone.

Steiner JA, Hofmann UAT, Christen P, Favre JM, Ferguson SJ, van Lenthe GH.

J Orthop Res. 2018 Mar;36(3):954-962. doi: 10.1002/jor.23721. Epub 2017 Sep 20.

11.

Feasibility of rigid 3D image registration of high-resolution peripheral quantitative computed tomography images of healing distal radius fractures.

de Jong JJA, Christen P, Plett RM, Chapurlat R, Geusens PP, van den Bergh JPW, Müller R, van Rietbergen B.

PLoS One. 2017 Jul 25;12(7):e0179413. doi: 10.1371/journal.pone.0179413. eCollection 2017.

12.

In vivo Visualisation and Quantification of Bone Resorption and Bone Formation from Time-Lapse Imaging.

Christen P, Müller R.

Curr Osteoporos Rep. 2017 Aug;15(4):311-317. doi: 10.1007/s11914-017-0372-1. Review.

PMID:
28639146
13.

Cadmium Causes Misfolding and Aggregation of Cytosolic Proteins in Yeast.

Jacobson T, Priya S, Sharma SK, Andersson S, Jakobsson S, Tanghe R, Ashouri A, Rauch S, Goloubinoff P, Christen P, Tamás MJ.

Mol Cell Biol. 2017 Aug 11;37(17). pii: e00490-16. doi: 10.1128/MCB.00490-16. Print 2017 Sep 1.

14.

A new antifungal and antiprotozoal bibenzyl derivative from Gavilea lutea.

Cretton S, Oyarzún A, Righi D, Sahib L, Kaiser M, Christen P, Fajardo V.

Nat Prod Res. 2018 Mar;32(6):695-701. doi: 10.1080/14786419.2017.1338287. Epub 2017 Jun 8.

PMID:
28595455
15.

Computational modeling of long-term effects of prophylactic vertebroplasty on bone adaptation.

Badilatti SD, Christen P, Ferguson SJ, Müller R.

Proc Inst Mech Eng H. 2017 May;231(5):423-431. doi: 10.1177/0954411916683222.

PMID:
28427315
16.

Cancer chemopreventive activity of compounds isolated from Waltheria indica.

Monteillier A, Cretton S, Ciclet O, Marcourt L, Ebrahimi SN, Christen P, Cuendet M.

J Ethnopharmacol. 2017 May 5;203:214-225. doi: 10.1016/j.jep.2017.03.048. Epub 2017 Mar 28.

PMID:
28359850
17.

Two New Hygroline and Tropane Alkaloids Isolated from Schizanthus hookeri and S. tricolor (Solanaceae).

Cretton S, Muñoz O, Tapia J, Marcourt L, Maes L, Christen P.

Nat Prod Commun. 2017 Mar;12(3):355-358.

PMID:
30549884
18.

A novel in silico method to quantify primary stability of screws in trabecular bone.

Steiner JA, Christen P, Affentranger R, Ferguson SJ, van Lenthe GH.

J Orthop Res. 2017 Nov;35(11):2415-2424. doi: 10.1002/jor.23551. Epub 2017 Mar 8.

19.

Passive Intestinal Absorption of Representative Plant Secondary Metabolites: A Physicochemical Study.

Petit C, Ceccarelli M, Cretton S, Houriet J, Skalicka-Woźniak K, Christen P, Carrupt PA, Goracci L, Wolfender JL.

Planta Med. 2017 May;83(8):718-726. doi: 10.1055/s-0043-101915. Epub 2017 Feb 13.

PMID:
28192813
20.

Hydrogen production by the hyperthermophilic bacterium Thermotoga maritima part I: effects of sulfured nutriments, with thiosulfate as model, on hydrogen production and growth.

Boileau C, Auria R, Davidson S, Casalot L, Christen P, Liebgott PP, Combet-Blanc Y.

Biotechnol Biofuels. 2016 Dec 19;9:269. doi: 10.1186/s13068-016-0678-8. eCollection 2016.

21.

Hydrogen production by the hyperthermophilic bacterium Thermotoga maritima Part II: modeling and experimental approaches for hydrogen production.

Auria R, Boileau C, Davidson S, Casalot L, Christen P, Liebgott PP, Combet-Blanc Y.

Biotechnol Biofuels. 2016 Dec 19;9:268. doi: 10.1186/s13068-016-0681-0. eCollection 2016.

22.

Load-adaptive bone remodeling simulations reveal osteoporotic microstructural and mechanical changes in whole human vertebrae.

Badilatti SD, Christen P, Parkinson I, Müller R.

J Biomech. 2016 Dec 8;49(16):3770-3779. doi: 10.1016/j.jbiomech.2016.10.002. Epub 2016 Oct 13.

PMID:
27793404
23.

Prediction of the Passive Intestinal Absorption of Medicinal Plant Extract Constituents with the Parallel Artificial Membrane Permeability Assay (PAMPA).

Petit C, Bujard A, Skalicka-Woźniak K, Cretton S, Houriet J, Christen P, Carrupt PA, Wolfender JL.

Planta Med. 2016 Mar;82(5):424-31. doi: 10.1055/s-0042-101247. Epub 2016 Feb 12.

PMID:
26872320
24.

Antifungal Quinoline Alkaloids from Waltheria indica.

Cretton S, Dorsaz S, Azzollini A, Favre-Godal Q, Marcourt L, Ebrahimi SN, Voinesco F, Michellod E, Sanglard D, Gindro K, Wolfender JL, Cuendet M, Christen P.

J Nat Prod. 2016 Feb 26;79(2):300-7. doi: 10.1021/acs.jnatprod.5b00896. Epub 2016 Feb 5.

PMID:
26848627
25.

Voxel size dependency, reproducibility and sensitivity of an in vivo bone loading estimation algorithm.

Christen P, Schulte FA, Zwahlen A, van Rietbergen B, Boutroy S, Melton LJ 3rd, Amin S, Khosla S, Goldhahn J, Müller R.

J R Soc Interface. 2016 Jan;13(114):20150991. doi: 10.1098/rsif.2015.0991.

26.

Privacy-preserving matching of similar patients.

Vatsalan D, Christen P.

J Biomed Inform. 2016 Feb;59:285-98. doi: 10.1016/j.jbi.2015.12.004. Epub 2015 Dec 17.

27.

Screening and Engineering the Synthetic Potential of Carboxylating Reductases from Central Metabolism and Polyketide Biosynthesis.

Peter DM, Schada von Borzyskowski L, Kiefer P, Christen P, Vorholt JA, Erb TJ.

Angew Chem Int Ed Engl. 2015 Nov 2;54(45):13457-61. doi: 10.1002/anie.201505282. Epub 2015 Sep 18.

PMID:
26383129
28.

Large-scale microstructural simulation of load-adaptive bone remodeling in whole human vertebrae.

Badilatti SD, Christen P, Levchuk A, Marangalou JH, van Rietbergen B, Parkinson I, Müller R.

Biomech Model Mechanobiol. 2016 Feb;15(1):83-95. doi: 10.1007/s10237-015-0715-8. Epub 2015 Aug 9.

PMID:
26255055
29.

Chemical constituents from Waltheria indica exert in vitro activity against Trypanosoma brucei and T. cruzi.

Cretton S, Bréant L, Pourrez L, Ambuehl C, Perozzo R, Marcourt L, Kaiser M, Cuendet M, Christen P.

Fitoterapia. 2015 Sep;105:55-60. doi: 10.1016/j.fitote.2015.06.007. Epub 2015 Jun 11.

PMID:
26072041
30.

A potential mechanism for allometric trabecular bone scaling in terrestrial mammals.

Christen P, Ito K, van Rietbergen B.

J Anat. 2015 Mar;226(3):236-43. doi: 10.1111/joa.12278. Epub 2015 Feb 4.

31.

Reverse pharmacology for developing an anti-malarial phytomedicine. The example of Argemone mexicana.

Simoes-Pires C, Hostettmann K, Haouala A, Cuendet M, Falquet J, Graz B, Christen P.

Int J Parasitol Drugs Drug Resist. 2014 Jul 30;4(3):338-46. doi: 10.1016/j.ijpddr.2014.07.001. eCollection 2014 Dec.

32.

Fast sampling method for mammalian cell metabolic analyses using liquid chromatography-mass spectrometry.

Martano G, Delmotte N, Kiefer P, Christen P, Kentner D, Bumann D, Vorholt JA.

Nat Protoc. 2015 Jan;10(1):1-11. doi: 10.1038/nprot.2014.198. Epub 2014 Dec 4.

PMID:
25474028
33.

Unexpected occurrence of caffeine in sleep-inducing herbal teas.

Mathona C, Edder P, Christen P, Bieri S.

Chimia (Aarau). 2014 Oct;68(10):705-9. doi: 10.2533/chimia.2014.705.

PMID:
25437162
34.

Antitrypanosomal quinoline alkaloids from the roots of Waltheria indica.

Cretton S, Breant L, Pourrez L, Ambuehl C, Marcourt L, Ebrahimi SN, Hamburger M, Perozzo R, Karimou S, Kaiser M, Cuendet M, Christen P.

J Nat Prod. 2014 Oct 24;77(10):2304-11. doi: 10.1021/np5006554. Epub 2014 Oct 14.

PMID:
25314007
35.

Survey of pyrrolizidine alkaloids in teas and herbal teas on the Swiss market using HPLC-MS/MS.

Mathon C, Edder P, Bieri S, Christen P.

Anal Bioanal Chem. 2014 Nov;406(28):7345-54. doi: 10.1007/s00216-014-8142-8. Epub 2014 Oct 7.

PMID:
25286874
36.

Bone remodelling in humans is load-driven but not lazy.

Christen P, Ito K, Ellouz R, Boutroy S, Sornay-Rendu E, Chapurlat RD, van Rietbergen B.

Nat Commun. 2014 Sep 11;5:4855. doi: 10.1038/ncomms5855.

PMID:
25209333
37.

Real-time assessment of possible electromagnetic-field-induced changes in protein conformation and thermal stability.

Beyer C, Christen P, Jelesarov I, Fröhlich J.

Bioelectromagnetics. 2014 Oct;35(7):470-8. doi: 10.1002/bem.21865. Epub 2014 Aug 14.

PMID:
25123495
38.

Heavy metals and metalloids as a cause for protein misfolding and aggregation.

Tamás MJ, Sharma SK, Ibstedt S, Jacobson T, Christen P.

Biomolecules. 2014 Feb 25;4(1):252-67. doi: 10.3390/biom4010252. Review.

39.

Determination of hip-joint loading patterns of living and extinct mammals using an inverse Wolff's law approach.

Christen P, Ito K, Galis F, van Rietbergen B.

Biomech Model Mechanobiol. 2015 Apr;14(2):427-32. doi: 10.1007/s10237-014-0602-8. Epub 2014 Jun 21.

PMID:
24952222
40.

Synthesis and in vitro evaluation of tropane halogenated-derivatives against malaria, sleeping sickness, Chagas disease and leishmaniasis.

Cretton S, Bartholomeusz TA, Mehl F, Allenbach Y, Matheeussen A, Cos P, Maes L, Christen P.

Med Chem. 2014;10(8):753-8.

PMID:
24813684
41.

Molecular biodiversity and recent analytical developments: a marriage of convenience.

Berkov S, Mutafova B, Christen P.

Biotechnol Adv. 2014 Nov 1;32(6):1102-10. doi: 10.1016/j.biotechadv.2014.04.005. Epub 2014 Apr 26. Review.

PMID:
24780152
42.

Challenges in longitudinal measurements with HR-pQCT: evaluation of a 3D registration method to improve bone microarchitecture and strength measurement reproducibility.

Ellouz R, Chapurlat R, van Rietbergen B, Christen P, Pialat JB, Boutroy S.

Bone. 2014 Jun;63:147-57. doi: 10.1016/j.bone.2014.03.001. Epub 2014 Mar 12.

PMID:
24614646
43.

Biochemical, transcriptional and translational evidences of the phenol-meta-degradation pathway by the hyperthermophilic Sulfolobus solfataricus 98/2.

Comte A, Christen P, Davidson S, Pophillat M, Lorquin J, Auria R, Simon G, Casalot L.

PLoS One. 2013 Dec 11;8(12):e82397. doi: 10.1371/journal.pone.0082397. eCollection 2013.

44.

Screening and determination of sibutramine in adulterated herbal slimming supplements by HPTLC-UV densitometry.

Mathon C, Ankli A, Reich E, Bieri S, Christen P.

Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2014;31(1):15-20. doi: 10.1080/19440049.2013.861934. Epub 2014 Jan 15.

PMID:
24215519
45.

High-throughput tandem-microwell assay identifies inhibitors of the hydrogen sulfide signaling pathway.

Zhou Y, Yu J, Lei X, Wu J, Niu Q, Zhang Y, Liu H, Christen P, Gehring H, Wu F.

Chem Commun (Camb). 2013 Dec 28;49(100):11782-4. doi: 10.1039/c3cc46719h.

PMID:
24213681
46.

Mutation in the C-di-AMP cyclase dacA affects fitness and resistance of methicillin resistant Staphylococcus aureus.

Dengler V, McCallum N, Kiefer P, Christen P, Patrignani A, Vorholt JA, Berger-Bächi B, Senn MM.

PLoS One. 2013 Aug 27;8(8):e73512. doi: 10.1371/journal.pone.0073512. eCollection 2013.

47.

Inhibition of cholinergic contractions of rat ileum by tkopane-type alkaloids present in Schizanthus hookeri.

Morales MA, Ahumada F, Castillo E, Burgos R, Christen P, Bustos V, Muñoz O.

Z Naturforsch C. 2013 May-Jun;68(5-6):203-9.

PMID:
23923617
48.

Medicinal plants of Chile: evaluation of their anti-Trypanosoma cruzi activity.

Muñoz OM, Maya JD, Ferreira J, Christen P, San Martin J, López-Muñoz R, Morello A, Kemmerling U.

Z Naturforsch C. 2013 May-Jun;68(5-6):198-202.

PMID:
23923616
49.

Analysis of the neurotoxin anisatin in star anise by LC-MS/MS.

Mathon C, Bongard B, Duret M, Ortelli D, Christen P, Bieri S.

Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2013;30(9):1598-605. doi: 10.1080/19440049.2013.804955. Epub 2013 Jun 27.

PMID:
23802692
50.

Experimental system for real-time assessment of potential changes in protein conformation induced by electromagnetic fields.

Beyer C, Christen P, Jelesarov I, Fröhlich J.

Bioelectromagnetics. 2013 Sep;34(6):419-28. doi: 10.1002/bem.21795. Epub 2013 May 2.

PMID:
23640851

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