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Items: 25

1.

Protection against Experimental Melioidosis with a Synthetic manno-Heptopyranose Hexasaccharide Glycoconjugate.

Scott AE, Christ WJ, George AJ, Stokes MG, Lohman GJ, Guo Y, Jones M, Titball RW, Atkins TP, Campbell AS, Prior JL.

Bioconjug Chem. 2016 Jun 15;27(6):1435-46. doi: 10.1021/acs.bioconjchem.5b00525. Epub 2016 May 17.

2.

Evaluation of a Group A Streptococcus synthetic oligosaccharide as vaccine candidate.

Kabanova A, Margarit I, Berti F, Romano MR, Grandi G, Bensi G, Chiarot E, Proietti D, Swennen E, Cappelletti E, Fontani P, Casini D, Adamo R, Pinto V, Skibinski D, Capo S, Buffi G, Gallotta M, Christ WJ, Campbell AS, Pena J, Seeberger PH, Rappuoli R, Costantino P.

Vaccine. 2010 Dec 10;29(1):104-14. doi: 10.1016/j.vaccine.2010.09.018. Epub 2010 Sep 24.

PMID:
20870056
3.

Inhibition of endotoxin response by synthetic TLR4 antagonists.

Hawkins LD, Christ WJ, Rossignol DP.

Curr Top Med Chem. 2004;4(11):1147-71. Review.

PMID:
15279606
4.

Synthesis of fluorescein labeled 7-methylguanosinemonophosphate.

Natarajan A, Moerke N, Fan YH, Chen H, Christ WJ, Wagner G, Halperin JA.

Bioorg Med Chem Lett. 2004 May 17;14(10):2657-60.

PMID:
15109672
5.

3,3-diaryl-1,3-dihydroindol-2-ones as antiproliferatives mediated by translation initiation inhibition.

Natarajan A, Fan YH, Chen H, Guo Y, Iyasere J, Harbinski F, Christ WJ, Aktas H, Halperin JA.

J Med Chem. 2004 Apr 8;47(8):1882-5.

PMID:
15055987
6.

Association of the endotoxin antagonist E5564 with high-density lipoproteins in vitro: dependence on low-density and triglyceride-rich lipoprotein concentrations.

Wasan KM, Sivak O, Cote RA, MacInnes AI, Boulanger KD, Lynn M, Christ WJ, Hawkins LD, Rossignol DP.

Antimicrob Agents Chemother. 2003 Sep;47(9):2796-803.

7.

Inhibition of endotoxin response by e5564, a novel Toll-like receptor 4-directed endotoxin antagonist.

Mullarkey M, Rose JR, Bristol J, Kawata T, Kimura A, Kobayashi S, Przetak M, Chow J, Gusovsky F, Christ WJ, Rossignol DP.

J Pharmacol Exp Ther. 2003 Mar;304(3):1093-102.

PMID:
12604686
8.

Examination of chlorpromazine and other amphipathic drugs on the activity of lipopolysaccharide antagonists, E5564 and E5531.

Yang H, Daun JM, Rose JR, Christ WJ, Gusovsky F, Chow JC.

J Endotoxin Res. 2000;6(6):447-52.

PMID:
11521069
9.

Inhibition of LPS-induced airway hyperresponsiveness and airway inflammation by LPS antagonists.

Schwartz DA, Christ WJ, Kleeberger SR, Wohlford-Lenane CL.

Am J Physiol Lung Cell Mol Physiol. 2001 Apr;280(4):L771-8.

10.

Selective formation of C-2 azidodeoxy-D-glucose derivatives from D-glucal precursors using the azidonitration reaction.

Seeberger PH, Roehrig S, Schell P, Wang Y, Christ WJ.

Carbohydr Res. 2000 Aug 18;328(1):61-9.

PMID:
11005576
11.

Structure-activity relationships of halichondrin B analogues: modifications at C.30-C.38.

Wang Y, Habgood GJ, Christ WJ, Kishi Y, Littlefield BA, Yu MJ.

Bioorg Med Chem Lett. 2000 May 15;10(10):1029-32.

PMID:
10843209
12.

Consequences of interaction of a lipophilic endotoxin antagonist with plasma lipoproteins.

Rose JR, Mullarkey MA, Christ WJ, Hawkins LD, Lynn M, Kishi Y, Wasan KM, Peteherych K, Rossignol DP.

Antimicrob Agents Chemother. 2000 Mar;44(3):504-10.

13.

Lipoprotein distribution of a novel endotoxin antagonist, E5531, in plasma from human subjects with various lipid levels.

Wasan KM, Strobel FW, Parrott SC, Lynn M, Christ WJ, Hawkins LD, Rossignol DP.

Antimicrob Agents Chemother. 1999 Oct;43(10):2562-4.

14.

E5531, a synthetic non-toxic lipid A derivative blocks the immunobiological activities of lipopolysaccharide.

Kawata T, Bristol JR, Rossignol DP, Rose JR, Kobayashi S, Yokohama H, Ishibashi A, Christ WJ, Katayama K, Yamatsu I, Kishi Y.

Br J Pharmacol. 1999 Jun;127(4):853-62.

15.

Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction.

Chow JC, Young DW, Golenbock DT, Christ WJ, Gusovsky F.

J Biol Chem. 1999 Apr 16;274(16):10689-92.

16.

CD11/CD18 and CD14 share a common lipid A signaling pathway.

Ingalls RR, Monks BG, Savedra R Jr, Christ WJ, Delude RL, Medvedev AE, Espevik T, Golenbock DT.

J Immunol. 1998 Nov 15;161(10):5413-20.

17.

Suppression of murine endotoxin response by E5531, a novel synthetic lipid A antagonist.

Kobayashi S, Kawata T, Kimura A, Miyamoto K, Katayama K, Yamatsu I, Rossignol DP, Christ WJ, Kishi Y.

Antimicrob Agents Chemother. 1998 Nov;42(11):2824-9.

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Protective effect of B464, a lipid A analog, on endotoxin-induced cellular responses and acute lung injury.

Soejima K, Ishizaka A, Urano T, Sayama K, Sakamaki F, Nakamura H, Terashima T, Waki Y, Tasaka S, Fujishima S, Kawata T, Christ WJ, Kanazawa M.

Am J Respir Crit Care Med. 1996 Oct;154(4 Pt 1):900-6.

PMID:
8887583
21.

E5531, a pure endotoxin antagonist of high potency.

Christ WJ, Asano O, Robidoux AL, Perez M, Wang Y, Dubuc GR, Gavin WE, Hawkins LD, McGuinness PD, Mullarkey MA, et al.

Science. 1995 Apr 7;268(5207):80-3.

PMID:
7701344
23.

Anti-endotoxin activity of a novel synthetic lipid A analog.

Kawata T, Bristol JR, Rose JR, Rossignol DP, Christ WJ, Asano O, Dubuc GR, Gavin WE, Hawkins LD, Kishi Y, et al.

Prog Clin Biol Res. 1995;392:499-509.

PMID:
8524958
24.

Suppression of lipopolysaccharide-induced macrophage nitric oxide and cytokine production in vitro by a novel lipopolysaccharide antagonist.

Wang SC, Rossignol DP, Christ WJ, Geller DA, Freeswick PD, Thai NL, Su GL, Simmons RL.

Surgery. 1994 Aug;116(2):339-46; discussion 446-7.

PMID:
7519366
25.

Linear and proximal benzo-separated alkylated xanthines as adenosine-receptor antagonists.

Schneller SW, Ibay AC, Christ WJ, Bruns RF.

J Med Chem. 1989 Oct;32(10):2247-54.

PMID:
2795597

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