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Items: 1 to 50 of 183

1.

Case Report on: Very Early Afterdepolarizations in HiPSC-Cardiomyocytes-An Artifact by Big Conductance Calcium Activated Potassium Current (Ibk,Ca).

Horváth A, Christ T, Koivumäki JT, Prondzynski M, Zech ATL, Spohn M, Saleem U, Mannhardt I, Ulmer B, Girdauskas E, Meyer C, Hansen A, Eschenhagen T, Lemoine MD.

Cells. 2020 Jan 20;9(1). pii: E253. doi: 10.3390/cells9010253.

2.

Efficacy and toxicity of reduced vs. standard dose pegylated asparaginase in adults with Philadelphia chromosome-negative acute lymphoblastic leukemia.

Derman BA, Streck M, Wynne J, Christ TN, Curran E, Stock W, Knoebel RW.

Leuk Lymphoma. 2019 Nov 4:1-9. doi: 10.1080/10428194.2019.1680839. [Epub ahead of print]

PMID:
31680584
3.

Disease modeling of a mutation in α-actinin 2 guides clinical therapy in hypertrophic cardiomyopathy.

Prondzynski M, Lemoine MD, Zech AT, Horváth A, Di Mauro V, Koivumäki JT, Kresin N, Busch J, Krause T, Krämer E, Schlossarek S, Spohn M, Friedrich FW, Münch J, Laufer SD, Redwood C, Volk AE, Hansen A, Mearini G, Catalucci D, Meyer C, Christ T, Patten M, Eschenhagen T, Carrier L.

EMBO Mol Med. 2019 Dec;11(12):e11115. doi: 10.15252/emmm.201911115. Epub 2019 Nov 3.

4.

Chronic intermittent tachypacing by an optogenetic approach induces arrhythmia vulnerability in human engineered heart tissue.

Lemme M, Braren I, Prondzynski M, Aksehirlioglu B, Ulmer BM, Schulze ML, Ismaili D, Meyer C, Hansen A, Christ T, Lemoine MD, Eschenhagen T.

Cardiovasc Res. 2019 Oct 9. pii: cvz245. doi: 10.1093/cvr/cvz245. [Epub ahead of print]

PMID:
31598634
5.

Divergent off-target effects of RSK N-terminal and C-terminal kinase inhibitors in cardiac myocytes.

Stathopoulou K, Schobesberger S, Bork NI, Sprenger JU, Perera RK, Sotoud H, Geertz B, David JP, Christ T, Nikolaev VO, Cuello F.

Cell Signal. 2019 Nov;63:109362. doi: 10.1016/j.cellsig.2019.109362. Epub 2019 Jul 22.

PMID:
31344438
6.

Investigating the Diagnostic Consistency and Incremental Validity Evidence of Curriculum-based Measurements of Oral Reading Rate and Comprehension.

Diggs CR, Christ TJ.

Contemp Sch Psychol. 2019 Jun;23(2):163-178. doi: 10.1007/s40688-018-0194-x. Epub 2018 Jun 11.

PMID:
31161073
7.

Cardiac glial cells release neurotrophic S100B upon catheter-based treatment of atrial fibrillation.

Scherschel K, Hedenus K, Jungen C, Lemoine MD, Rübsamen N, Veldkamp MW, Klatt N, Lindner D, Westermann D, Casini S, Kuklik P, Eickholt C, Klöcker N, Shivkumar K, Christ T, Zeller T, Willems S, Meyer C.

Sci Transl Med. 2019 May 22;11(493). pii: eaav7770. doi: 10.1126/scitranslmed.aav7770.

PMID:
31118294
8.

Leveraging technology: A multi-component personalized system of instruction to teach sight words.

Hammerschmidt-Snidarich SM, Edwards LM, Christ TJ, Thayer AJ.

J Sch Psychol. 2019 Feb;72:150-171. doi: 10.1016/j.jsp.2018.12.005. Epub 2019 Feb 4.

PMID:
30819460
9.

DPP10 is a new regulator of Nav1.5 channels in human heart.

Belau F, Metzner K, Christ T, Ravens U, Schaefer M, Künzel S, Li W, Wettwer E, Dobrev D, El-Armouche A, Kämmerer S.

Int J Cardiol. 2019 Jun 1;284:68-73. doi: 10.1016/j.ijcard.2018.12.072. Epub 2019 Jan 3.

PMID:
30638748
10.

Olaparib: A tale of two dosage forms.

Christ TN.

Semin Oncol. 2019 Feb;46(1):100-101. doi: 10.1053/j.seminoncol.2018.11.003. Epub 2018 Dec 19.

PMID:
30583807
11.

Mechanistic role of the CREB-regulated transcription coactivator 1 in cardiac hypertrophy.

Morhenn K, Quentin T, Wichmann H, Steinmetz M, Prondzynski M, Söhren KD, Christ T, Geertz B, Schröder S, Schöndube FA, Hasenfuss G, Schlossarek S, Zimmermann WH, Carrier L, Eschenhagen T, Cardinaux JR, Lutz S, Oetjen E.

J Mol Cell Cardiol. 2019 Feb;127:31-43. doi: 10.1016/j.yjmcc.2018.12.001. Epub 2018 Dec 4.

PMID:
30521840
12.

Long-term results after the Ross procedure with the decellularized AutoTissue Matrix P® bioprosthesis used for pulmonary valve replacement.

Christ T, Paun AC, Grubitzsch H, Holinski S, Falk V, Dushe S.

Eur J Cardiothorac Surg. 2019 May 1;55(5):885-892. doi: 10.1093/ejcts/ezy377.

PMID:
30508165
13.

Treatment of Acute Promyelocytic Leukemia in Adults.

Osman AEG, Anderson J, Churpek JE, Christ TN, Curran E, Godley LA, Liu H, Thirman MJ, Odenike T, Stock W, Larson RA.

J Oncol Pract. 2018 Nov;14(11):649-657. doi: 10.1200/JOP.18.00328. Review.

PMID:
30423270
14.

Atrial-like Engineered Heart Tissue: An In Vitro Model of the Human Atrium.

Lemme M, Ulmer BM, Lemoine MD, Zech ATL, Flenner F, Ravens U, Reichenspurner H, Rol-Garcia M, Smith G, Hansen A, Christ T, Eschenhagen T.

Stem Cell Reports. 2018 Dec 11;11(6):1378-1390. doi: 10.1016/j.stemcr.2018.10.008. Epub 2018 Nov 8.

15.

Normalization of force to muscle cross-sectional area: A helpful attempt to reduce data scattering in contractility studies?

Pecha S, Koivumäki J, Geelhoed B, Kempe R, Berk E, Engel A, Reichenspurner H, Eschenhagen T, Ravens U, Kaumann A, Christ T.

Acta Physiol (Oxf). 2018 Dec;224(4):e13202. doi: 10.1111/apha.13202. No abstract available.

PMID:
30338659
16.

German Cardiac Society Working Group on Cellular Electrophysiology state-of-the-art paper: impact of molecular mechanisms on clinical arrhythmia management.

Thomas D, Christ T, Fabritz L, Goette A, Hammwöhner M, Heijman J, Kockskämper J, Linz D, Odening KE, Schweizer PA, Wakili R, Voigt N.

Clin Res Cardiol. 2019 Jun;108(6):577-599. doi: 10.1007/s00392-018-1377-1. Epub 2018 Oct 10. Review.

PMID:
30306295
17.

Evaluation of schedule frequency and density when monitoring progress with curriculum-based measurement.

January SA, Van Norman ER, Christ TJ, Ardoin SP, Eckert TL, White MJ.

Sch Psychol Q. 2019 Jan;34(1):119-127. doi: 10.1037/spq0000274. Epub 2018 Oct 4.

PMID:
30284886
18.

Rat atrial engineered heart tissue: a new in vitro model to study atrial biology.

Krause J, Löser A, Lemoine MD, Christ T, Scherschel K, Meyer C, Blankenberg S, Zeller T, Eschenhagen T, Stenzig J.

Basic Res Cardiol. 2018 Sep 3;113(5):41. doi: 10.1007/s00395-018-0701-2.

PMID:
30178427
19.

Impact of a Clinical Decision Support Tool on Cancer Pain Management in Opioid-Tolerant Inpatients.

Christ TN, Villadolid JJ, Choksi A, Malec M, Knoebel RW.

Hosp Pharm. 2018 Jul;53(4):256-262. doi: 10.1177/0018578717746369. Epub 2017 Dec 11.

20.

Human Induced Pluripotent Stem Cell-Derived Engineered Heart Tissue as a Sensitive Test System for QT Prolongation and Arrhythmic Triggers.

Lemoine MD, Krause T, Koivumäki JT, Prondzynski M, Schulze ML, Girdauskas E, Willems S, Hansen A, Eschenhagen T, Christ T.

Circ Arrhythm Electrophysiol. 2018 Jul;11(7):e006035. doi: 10.1161/CIRCEP.117.006035.

PMID:
29925535
21.

Inhibition of Small Conductance Calcium-Activated Potassium (SK) Channels Prevents Arrhythmias in Rat Atria During β-Adrenergic and Muscarinic Receptor Activation.

Skibsbye L, Bengaard AK, Uldum-Nielsen AM, Boddum K, Christ T, Jespersen T.

Front Physiol. 2018 Jun 5;9:510. doi: 10.3389/fphys.2018.00510. eCollection 2018.

22.

Comparison of the incidence of febrile neutropenia in obese and normal weight breast cancer patients receiving myelosuppressive chemotherapy and prophylactic pegfilgrastim.

Collins JM, Fleming GF, Christ TN.

J Oncol Pharm Pract. 2019 Jul;25(5):1112-1118. doi: 10.1177/1078155218776471. Epub 2018 May 17.

PMID:
29768957
23.

In Vitro Negative Inotropic Effect of Low Concentrations of Bupivacaine Relates to Diminished Ca2+ Sensitivity but Not to Ca2+ Handling or β-Adrenoceptor Signaling.

Flenner F, Arlt N, Nasib M, Schobesberger S, Koch T, Ravens U, Friedrich F, Nikolaev V, Christ T, Stehr SN.

Anesthesiology. 2018 Jun;128(6):1175-1186. doi: 10.1097/ALN.0000000000002180.

PMID:
29547406
24.

Low Resting Membrane Potential and Low Inward Rectifier Potassium Currents Are Not Inherent Features of hiPSC-Derived Cardiomyocytes.

Horváth A, Lemoine MD, Löser A, Mannhardt I, Flenner F, Uzun AU, Neuber C, Breckwoldt K, Hansen A, Girdauskas E, Reichenspurner H, Willems S, Jost N, Wettwer E, Eschenhagen T, Christ T.

Stem Cell Reports. 2018 Mar 13;10(3):822-833. doi: 10.1016/j.stemcr.2018.01.012. Epub 2018 Feb 8.

25.

Hemodynamics of Pericardial Aortic Valves: Contemporary Stented versus Stentless Valves in a Matched Comparison.

Christ T, Holinski S, Zhigalov K, Zielinski CB, Grubitzsch H.

Ann Thorac Cardiovasc Surg. 2017 Dec 20;23(6):298-303. doi: 10.5761/atcs.oa.17-00061. Epub 2017 Sep 8.

26.

Risks and Challenges of Surgery for Aortic Prosthetic Valve Endocarditis.

Grubitzsch H, Tarar W, Claus B, Gabbieri D, Falk V, Christ T.

Heart Lung Circ. 2018 Mar;27(3):333-343. doi: 10.1016/j.hlc.2017.05.143. Epub 2017 Jun 21.

PMID:
28764880
27.

Human iPSC-derived cardiomyocytes cultured in 3D engineered heart tissue show physiological upstroke velocity and sodium current density.

Lemoine MD, Mannhardt I, Breckwoldt K, Prondzynski M, Flenner F, Ulmer B, Hirt MN, Neuber C, Horváth A, Kloth B, Reichenspurner H, Willems S, Hansen A, Eschenhagen T, Christ T.

Sci Rep. 2017 Jul 14;7(1):5464. doi: 10.1038/s41598-017-05600-w.

28.

AkrinorTM, a Cafedrine/ Theodrenaline Mixture (20:1), Increases Force of Contraction of Human Atrial Myocardium But Does Not Constrict Internal Mammary Artery In Vitro.

Kloth B, Pecha S, Moritz E, Schneeberger Y, Söhren KD, Schwedhelm E, Reichenspurner H, Eschenhagen T, Böger RH, Christ T, Stehr SN.

Front Pharmacol. 2017 May 23;8:272. doi: 10.3389/fphar.2017.00272. eCollection 2017.

29.

EDC Cross-linking of Decellularized Tissue: A Promising Approach?

Lehmann N, Christ T, Daugs A, Bloch O, Holinski S.

Tissue Eng Part A. 2017 Jul;23(13-14):675-682. doi: 10.1089/ten.TEA.2016.0416. Epub 2017 May 15.

PMID:
28457180
30.

Blinded Contractility Analysis in hiPSC-Cardiomyocytes in Engineered Heart Tissue Format: Comparison With Human Atrial Trabeculae.

Mannhardt I, Eder A, Dumotier B, Prondzynski M, Krämer E, Traebert M, Söhren KD, Flenner F, Stathopoulou K, Lemoine MD, Carrier L, Christ T, Eschenhagen T, Hansen A.

Toxicol Sci. 2017 Jul 1;158(1):164-175. doi: 10.1093/toxsci/kfx081.

31.

Incidence of asparaginase-related hepatotoxicity, pancreatitis, and thrombotic events in adults with acute lymphoblastic leukemia treated with a pediatric-inspired regimen.

Christ TN, Stock W, Knoebel RW.

J Oncol Pharm Pract. 2018 Jun;24(4):299-308. doi: 10.1177/1078155217701291. Epub 2017 Mar 29.

PMID:
28355969
32.

Long-Term Outcome of the Sorin Freedom SOLO Stentless Aortic Valve.

Christ T, Claus B, Zielinski C, Falk V, Grubitzsch H.

J Heart Valve Dis. 2016 Nov;25(6):679-684.

PMID:
28290166
33.

Cafedrine/Theodrenaline (20:1) Is an Established Alternative for the Management of Arterial Hypotension in Germany-a Review Based on a Systematic Literature Search.

Bein B, Christ T, Eberhart LH.

Front Pharmacol. 2017 Feb 21;8:68. doi: 10.3389/fphar.2017.00068. eCollection 2017. Review.

34.

Redo procedures for degenerated stentless aortic xenografts and the role of valve-in-valve transcatheter techniques.

Grubitzsch H, Zobel S, Christ T, Holinski S, Stangl K, Treskatsch S, Falk V, Laule M.

Eur J Cardiothorac Surg. 2017 Apr 1;51(4):653-659. doi: 10.1093/ejcts/ezw397.

PMID:
28062549
35.

Sutureless Aortic Valve Replacement in a Patient with Transfemoral Aortic Valve Replacement and Left Ventricular Hypertrophy.

Christ T, Dohmen PM, Laule M, Stangl K, Konertz W.

Thorac Cardiovasc Surg Rep. 2016 Dec;5(1):21-23. doi: 10.1055/s-0035-1554991. Epub 2015 Jul 10.

36.

Clinical outcome and hemodynamic behavior of the Labcor Dokimos Plus aortic valve.

Christ T, Zhigalov K, Konertz W, Holinski S.

J Cardiothorac Surg. 2016 Nov 29;11(1):160.

37.

Refractoriness in human atria: Time and voltage dependence of sodium channel availability.

Skibsbye L, Jespersen T, Christ T, Maleckar MM, van den Brink J, Tavi P, Koivumäki JT.

J Mol Cell Cardiol. 2016 Dec;101:26-34. doi: 10.1016/j.yjmcc.2016.10.009. Epub 2016 Oct 20.

PMID:
27773652
38.

Ca(2+)-Currents in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Effects of Two Different Culture Conditions.

Uzun AU, Mannhardt I, Breckwoldt K, Horváth A, Johannsen SS, Hansen A, Eschenhagen T, Christ T.

Front Pharmacol. 2016 Sep 12;7:300. doi: 10.3389/fphar.2016.00300. eCollection 2016.

39.

How accurate are interpretations of curriculum-based measurement progress monitoring data? Visual analysis versus decision rules.

Van Norman ER, Christ TJ.

J Sch Psychol. 2016 Oct;58:41-55. doi: 10.1016/j.jsp.2016.07.003. Epub 2016 Aug 3.

PMID:
27586069
40.

The Ross Procedure in Adults: Long-Term Results of Homografts and Stentless Xenografts for Pulmonary Valve Replacement.

Christ T, Claus B, Woythal N, Dushe S, Falk V, Grubitzsch H.

Thorac Cardiovasc Surg. 2017 Dec;65(8):656-661. doi: 10.1055/s-0036-1586157. Epub 2016 Aug 10.

PMID:
27508999
41.

Block of Na(+)/Ca(2+) exchanger by SEA0400 in human right atrial preparations from patients in sinus rhythm and in atrial fibrillation.

Christ T, Kovács PP, Acsai K, Knaut M, Eschenhagen T, Jost N, Varró A, Wettwer E, Ravens U.

Eur J Pharmacol. 2016 Oct 5;788:286-293. doi: 10.1016/j.ejphar.2016.06.050. Epub 2016 Jun 29.

PMID:
27373849
42.

Frozen Elephant Trunk Technique in a Patient with Multiple Previous Cardiac Procedures: A Case Report.

Christ T, Lembcke A, Laule M, Dohmen P.

Med Sci Monit Basic Res. 2016 Jun 30;22:67-9.

43.

In permanent atrial fibrillation, PDE3 reduces force responses to 5-HT, but PDE3 and PDE4 do not cause the blunting of atrial arrhythmias.

Berk E, Christ T, Schwarz S, Ravens U, Knaut M, Kaumann AJ.

Br J Pharmacol. 2016 Aug;173(16):2478-89. doi: 10.1111/bph.13525. Epub 2016 Jul 18.

44.

Human Engineered Heart Tissue: Analysis of Contractile Force.

Mannhardt I, Breckwoldt K, Letuffe-Brenière D, Schaaf S, Schulz H, Neuber C, Benzin A, Werner T, Eder A, Schulze T, Klampe B, Christ T, Hirt MN, Huebner N, Moretti A, Eschenhagen T, Hansen A.

Stem Cell Reports. 2016 Jul 12;7(1):29-42. doi: 10.1016/j.stemcr.2016.04.011. Epub 2016 May 19.

45.

Surgery for prosthetic valve endocarditis: associations between morbidity, mortality and costs.

Grubitzsch H, Christ T, Melzer C, Kastrup M, Treskatsch S, Konertz W.

Interact Cardiovasc Thorac Surg. 2016 Jun;22(6):784-91. doi: 10.1093/icvts/ivw035. Epub 2016 Mar 9.

46.

Ranolazine antagonizes catecholamine-induced dysfunction in isolated cardiomyocytes, but lacks long-term therapeutic effects in vivo in a mouse model of hypertrophic cardiomyopathy.

Flenner F, Friedrich FW, Ungeheuer N, Christ T, Geertz B, Reischmann S, Wagner S, Stathopoulou K, Söhren KD, Weinberger F, Schwedhelm E, Cuello F, Maier LS, Eschenhagen T, Carrier L.

Cardiovasc Res. 2016 Jan 1;109(1):90-102. doi: 10.1093/cvr/cvv247. Epub 2015 Nov 3.

PMID:
26531128
47.

β 1 Adrenoceptor antagonistic effects of the supposedly selective β 2 adrenoceptor antagonist ICI 118,551 on the positive inotropic effect of adrenaline in murine hearts.

Pecha S, Flenner F, Söhren KD, Lorenz K, Eschenhagen T, Christ T.

Pharmacol Res Perspect. 2015 Oct;3(5):e00168. doi: 10.1002/prp2.168. Epub 2015 Jul 31.

48.

Reliability and agreement in student ratings of the class environment.

Nelson PM, Christ TJ.

Sch Psychol Q. 2016 Sep;31(3):419-430. doi: 10.1037/spq0000127. Epub 2015 Oct 26.

PMID:
26501396
49.

The St. Jude Toronto stentless bioprosthesis: up to 20 years follow-up in younger patients.

Christ T, Claus B, Borck R, Konertz W, Grubitzsch H.

Heart Surg Forum. 2015 Aug 30;18(4):E129-33. doi: 10.1532/hsf.1252.

PMID:
26334847
50.

Risk and Outcome of Aortic Valve Surgery in the Transcatheter Valve Era: The Gender Aspect.

Heinze G, Christ T, Leonards CO, Dohmen PM, Konertz W.

Ann Thorac Cardiovasc Surg. 2015;21(5):446-51. doi: 10.5761/atcs.oa.14-00291. Epub 2015 May 25.

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