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Items: 1 to 50 of 59

1.

Improved multilineage human hematopoietic reconstitution and function in NSGS mice.

Wunderlich M, Chou FS, Sexton C, Presicce P, Chougnet CA, Aliberti J, Mulloy JC.

PLoS One. 2018 Dec 12;13(12):e0209034. doi: 10.1371/journal.pone.0209034. eCollection 2018.

2.

Regulatory T Cells As Potential Targets for HIV Cure Research.

Kleinman AJ, Sivanandham R, Pandrea I, Chougnet CA, Apetrei C.

Front Immunol. 2018 Apr 13;9:734. doi: 10.3389/fimmu.2018.00734. eCollection 2018. Review.

3.

Interleukin 2 Promotes Hepatic Regulatory T Cell Responses and Protects From Biliary Fibrosis in Murine Sclerosing Cholangitis.

Taylor AE, Carey AN, Kudira R, Lages CS, Shi T, Lam S, Karns R, Simmons J, Shanmukhappa K, Almanan M, Chougnet CA, Miethke AG.

Hepatology. 2018 Nov;68(5):1905-1921. doi: 10.1002/hep.30061. Epub 2018 Sep 30.

4.

Human fetal immune cells fight back.

Chougnet CA.

Sci Transl Med. 2018 Apr 25;10(438). pii: eaat3910. doi: 10.1126/scitranslmed.aat3910. Review.

5.

IL-1 signaling mediates intrauterine inflammation and chorio-decidua neutrophil recruitment and activation.

Presicce P, Park CW, Senthamaraikannan P, Bhattacharyya S, Jackson C, Kong F, Rueda CM, DeFranco E, Miller LA, Hildeman DA, Salomonis N, Chougnet CA, Jobe AH, Kallapur SG.

JCI Insight. 2018 Mar 22;3(6). pii: 98306. doi: 10.1172/jci.insight.98306.

6.

Regulatory T cells in retroviral infections.

Hasenkrug KJ, Chougnet CA, Dittmer U.

PLoS Pathog. 2018 Feb 15;14(2):e1006776. doi: 10.1371/journal.ppat.1006776. eCollection 2018 Feb. Review.

7.

High density lipoproteins selectively promote the survival of human regulatory T cells.

Rueda CM, Rodríguez-Perea AL, Moreno-Fernandez M, Jackson CM, Melchior JT, Davidson WS, Chougnet CA.

J Lipid Res. 2017 Aug;58(8):1514-1523. doi: 10.1194/jlr.M072835. Epub 2017 Apr 4.

8.

IL-1β induced HIF-1α inhibits the differentiation of human FOXP3+ T cells.

Feldhoff LM, Rueda CM, Moreno-Fernandez ME, Sauer J, Jackson CM, Chougnet CA, Rupp J.

Sci Rep. 2017 Mar 28;7(1):465. doi: 10.1038/s41598-017-00508-x.

9.

Type I interferons regulate susceptibility to inflammation-induced preterm birth.

Cappelletti M, Presicce P, Lawson MJ, Chaturvedi V, Stankiewicz TE, Vanoni S, Harley IT, McAlees JW, Giles DA, Moreno-Fernandez ME, Rueda CM, Senthamaraikannan P, Sun X, Karns R, Hoebe K, Janssen EM, Karp CL, Hildeman DA, Hogan SP, Kallapur SG, Chougnet CA, Way SS, Divanovic S.

JCI Insight. 2017 Mar 9;2(5):e91288. doi: 10.1172/jci.insight.91288.

10.

Maternal house dust mite exposure during pregnancy enhances severity of house dust mite-induced asthma in murine offspring.

Richgels PK, Yamani A, Chougnet CA, Lewkowich IP.

J Allergy Clin Immunol. 2017 Nov;140(5):1404-1415.e9. doi: 10.1016/j.jaci.2016.12.972. Epub 2017 Feb 9.

11.

Pro-inflammatory immune responses in leukocytes of premature infants exposed to maternal chorioamnionitis or funisitis.

Jackson CM, Wells CB, Tabangin ME, Meinzen-Derr J, Jobe AH, Chougnet CA.

Pediatr Res. 2017 Feb;81(2):384-390. doi: 10.1038/pr.2016.232. Epub 2016 Nov 4.

12.

Intra-amniotic Ureaplasma parvum-Induced Maternal and Fetal Inflammation and Immune Responses in Rhesus Macaques.

Senthamaraikannan P, Presicce P, Rueda CM, Maneenil G, Schmidt AF, Miller LA, Waites KB, Jobe AH, Kallapur SG, Chougnet CA.

J Infect Dis. 2016 Nov 15;214(10):1597-1604. Epub 2016 Sep 6.

13.

Intra-amniotic LPS causes acute neuroinflammation in preterm rhesus macaques.

Schmidt AF, Kannan PS, Chougnet CA, Danzer SC, Miller LA, Jobe AH, Kallapur SG.

J Neuroinflammation. 2016 Sep 6;13(1):238. doi: 10.1186/s12974-016-0706-4.

14.

Regulatory T-Cell-Mediated Suppression of Conventional T-Cells and Dendritic Cells by Different cAMP Intracellular Pathways.

Rueda CM, Jackson CM, Chougnet CA.

Front Immunol. 2016 Jun 2;7:216. doi: 10.3389/fimmu.2016.00216. eCollection 2016. Review.

15.

Lipopolysaccharide-Induced Chorioamnionitis Promotes IL-1-Dependent Inflammatory FOXP3+ CD4+ T Cells in the Fetal Rhesus Macaque.

Rueda CM, Presicce P, Jackson CM, Miller LA, Kallapur SG, Jobe AH, Chougnet CA.

J Immunol. 2016 May 1;196(9):3706-15. doi: 10.4049/jimmunol.1502613. Epub 2016 Apr 1.

16.

Pulmonary Morbidity in Infancy after Exposure to Chorioamnionitis in Late Preterm Infants.

McDowell KM, Jobe AH, Fenchel M, Hardie WD, Gisslen T, Young LR, Chougnet CA, Davis SD, Kallapur SG.

Ann Am Thorac Soc. 2016 Jun;13(6):867-76. doi: 10.1513/AnnalsATS.201507-411OC.

17.

Fetal inflammation associated with minimal acute morbidity in moderate/late preterm infants.

Gisslen T, Alvarez M, Wells C, Soo MT, Lambers DS, Knox CL, Meinzen-Derr JK, Chougnet CA, Jobe AH, Kallapur SG.

Arch Dis Child Fetal Neonatal Ed. 2016 Nov;101(6):F513-F519. doi: 10.1136/archdischild-2015-308518. Epub 2016 Mar 23.

PMID:
27010018
18.

The placental membrane microbiome is altered among subjects with spontaneous preterm birth with and without chorioamnionitis.

Prince AL, Ma J, Kannan PS, Alvarez M, Gisslen T, Harris RA, Sweeney EL, Knox CL, Lambers DS, Jobe AH, Chougnet CA, Kallapur SG, Aagaard KM.

Am J Obstet Gynecol. 2016 May;214(5):627.e1-627.e16. doi: 10.1016/j.ajog.2016.01.193. Epub 2016 Mar 7.

19.

Placental Infection With Ureaplasma species Is Associated With Histologic Chorioamnionitis and Adverse Outcomes in Moderately Preterm and Late-Preterm Infants.

Sweeney EL, Kallapur SG, Gisslen T, Lambers DS, Chougnet CA, Stephenson SA, Jobe AH, Knox CL.

J Infect Dis. 2016 Apr 15;213(8):1340-7. doi: 10.1093/infdis/jiv587. Epub 2015 Dec 15.

20.

A Novel Role for the Receptor of the Complement Cleavage Fragment C5a, C5aR1, in CCR5-Mediated Entry of HIV into Macrophages.

Moreno-Fernandez ME, Aliberti J, Groeneweg S, Köhl J, Chougnet CA.

AIDS Res Hum Retroviruses. 2016 Apr;32(4):399-408. doi: 10.1089/AID.2015.0099. Epub 2015 Dec 15.

21.

Loss of Phagocytic and Antigen Cross-Presenting Capacity in Aging Dendritic Cells Is Associated with Mitochondrial Dysfunction.

Chougnet CA, Thacker RI, Shehata HM, Hennies CM, Lehn MA, Lages CS, Janssen EM.

J Immunol. 2015 Sep 15;195(6):2624-32. doi: 10.4049/jimmunol.1501006. Epub 2015 Aug 5.

22.

AUTOIMMUNE DISEASE. Patients with LRBA deficiency show CTLA4 loss and immune dysregulation responsive to abatacept therapy.

Lo B, Zhang K, Lu W, Zheng L, Zhang Q, Kanellopoulou C, Zhang Y, Liu Z, Fritz JM, Marsh R, Husami A, Kissell D, Nortman S, Chaturvedi V, Haines H, Young LR, Mo J, Filipovich AH, Bleesing JJ, Mustillo P, Stephens M, Rueda CM, Chougnet CA, Hoebe K, McElwee J, Hughes JD, Karakoc-Aydiner E, Matthews HF, Price S, Su HC, Rao VK, Lenardo MJ, Jordan MB.

Science. 2015 Jul 24;349(6246):436-40. doi: 10.1126/science.aaa1663.

23.

IL-6 and ICOS Antagonize Bim and Promote Regulatory T Cell Accrual with Age.

Raynor J, Karns R, Almanan M, Li KP, Divanovic S, Chougnet CA, Hildeman DA.

J Immunol. 2015 Aug 1;195(3):944-52. doi: 10.4049/jimmunol.1500443. Epub 2015 Jun 24.

24.

Neonatal regulatory T cells have reduced capacity to suppress dendritic cell function.

Rueda CM, Moreno-Fernandez ME, Jackson CM, Kallapur SG, Jobe AH, Chougnet CA.

Eur J Immunol. 2015 Sep;45(9):2582-92. doi: 10.1002/eji.201445371. Epub 2015 Jun 25.

25.

Prophylactic Interleukin-2 Treatment Prevents Fetal Gut Inflammation and Injury in an Ovine Model of Chorioamnionitis.

Nikiforou M, Vanderlocht J, Chougnet CA, Jellema RK, Ophelders DR, Joosten M, Kloosterboer N, Senden-Gijsbers BL, Germeraad WT, Kramer BW, Wolfs TG.

Inflamm Bowel Dis. 2015 Sep;21(9):2026-38. doi: 10.1097/MIB.0000000000000455.

PMID:
26002542
26.

Statins increase the frequency of circulating CD4+ FOXP3+ regulatory T cells in healthy individuals.

Rodríguez-Perea AL, Montoya CJ, Olek S, Chougnet CA, Velilla PA.

J Immunol Res. 2015;2015:762506. doi: 10.1155/2015/762506. Epub 2015 Feb 22.

27.

The aged nonhematopoietic environment impairs natural killer cell maturation and function.

Shehata HM, Hoebe K, Chougnet CA.

Aging Cell. 2015 Apr;14(2):191-9. doi: 10.1111/acel.12303. Epub 2015 Feb 9.

28.

Neutrophil recruitment and activation in decidua with intra-amniotic IL-1beta in the preterm rhesus macaque.

Presicce P, Senthamaraikannan P, Alvarez M, Rueda CM, Cappelletti M, Miller LA, Jobe AH, Chougnet CA, Kallapur SG.

Biol Reprod. 2015 Feb;92(2):56. doi: 10.1095/biolreprod.114.124420. Epub 2014 Dec 23.

29.

Blocking lymphocyte trafficking with FTY720 prevents inflammation-sensitized hypoxic-ischemic brain injury in newborns.

Yang D, Sun YY, Bhaumik SK, Li Y, Baumann JM, Lin X, Zhang Y, Lin SH, Dunn RS, Liu CY, Shie FS, Lee YH, Wills-Karp M, Chougnet CA, Kallapur SG, Lewkowich IP, Lindquist DM, Murali-Krishna K, Kuan CY.

J Neurosci. 2014 Dec 3;34(49):16467-81. doi: 10.1523/JNEUROSCI.2582-14.2014.

30.

Effect of chorioamnionitis on regulatory T cells in moderate/late preterm neonates.

Rueda CM, Wells CB, Gisslen T, Jobe AH, Kallapur SG, Chougnet CA.

Hum Immunol. 2015 Jan;76(1):65-73. doi: 10.1016/j.humimm.2014.10.016. Epub 2014 Nov 8.

31.

Toxoplasma gondii- derived profilin triggers human toll-like receptor 5-dependent cytokine production.

Salazar Gonzalez RM, Shehata H, O'Connell MJ, Yang Y, Moreno-Fernandez ME, Chougnet CA, Aliberti J.

J Innate Immun. 2014;6(5):685-94. doi: 10.1159/000362367. Epub 2014 May 23.

32.

Regulatory T Cells Diminish HIV Infection in Dendritic Cells - Conventional CD4(+) T Cell Clusters.

Moreno-Fernandez ME, Joedicke JJ, Chougnet CA.

Front Immunol. 2014 May 8;5:199. doi: 10.3389/fimmu.2014.00199. eCollection 2014.

33.

Fetal immune response to chorioamnionitis.

Kallapur SG, Presicce P, Rueda CM, Jobe AH, Chougnet CA.

Semin Reprod Med. 2014 Jan;32(1):56-67. doi: 10.1055/s-0033-1361823. Epub 2014 Jan 3. Review.

34.

Incomplete normalization of regulatory t-cell frequency in the gut mucosa of Colombian HIV-infected patients receiving long-term antiretroviral treatment.

Rueda CM, Velilla PA, Chougnet CA, Rugeles MT.

PLoS One. 2013 Aug 15;8(8):e71062. doi: 10.1371/journal.pone.0071062. eCollection 2013.

35.

IL-15 Fosters Age-Driven Regulatory T Cell Accrual in the Face of Declining IL-2 Levels.

Raynor J, Sholl A, Plas DR, Bouillet P, Chougnet CA, Hildeman DA.

Front Immunol. 2013 Jun 24;4:161. doi: 10.3389/fimmu.2013.00161. eCollection 2013.

36.

Intra-amniotic IL-1β induces fetal inflammation in rhesus monkeys and alters the regulatory T cell/IL-17 balance.

Kallapur SG, Presicce P, Senthamaraikannan P, Alvarez M, Tarantal AF, Miller LM, Jobe AH, Chougnet CA.

J Immunol. 2013 Aug 1;191(3):1102-9. doi: 10.4049/jimmunol.1300270. Epub 2013 Jun 21.

37.

In vitro HIV infection impairs the capacity of myeloid dendritic cells to induce regulatory T cells.

Presicce P, Moreno-Fernandez ME, Rusie LK, Fichtenbaum C, Chougnet CA.

PLoS One. 2012;7(8):e42802. doi: 10.1371/journal.pone.0042802. Epub 2012 Aug 13.

38.

Homeostasis and function of regulatory T cells in HIV/SIV infection.

Moreno-Fernandez ME, Presicce P, Chougnet CA.

J Virol. 2012 Oct;86(19):10262-9. doi: 10.1128/JVI.00993-12. Epub 2012 Jul 18. Review.

39.

Homeostasis and function of regulatory T cells in aging.

Raynor J, Lages CS, Shehata H, Hildeman DA, Chougnet CA.

Curr Opin Immunol. 2012 Aug;24(4):482-7. doi: 10.1016/j.coi.2012.04.005. Epub 2012 May 5. Review.

40.

Regulatory T cells control the CD8 adaptive immune response at the time of ductal obstruction in experimental biliary atresia.

Lages CS, Simmons J, Chougnet CA, Miethke AG.

Hepatology. 2012 Jul;56(1):219-27. doi: 10.1002/hep.25662. Epub 2012 Jun 6.

41.

HIV-induced T-cell activation/exhaustion in rectal mucosa is controlled only partially by antiretroviral treatment.

Rueda CM, Velilla PA, Chougnet CA, Montoya CJ, Rugeles MT.

PLoS One. 2012;7(1):e30307. doi: 10.1371/journal.pone.0030307. Epub 2012 Jan 19.

42.

Frequency of circulating regulatory T cells increases during chronic HIV infection and is largely controlled by highly active antiretroviral therapy.

Presicce P, Orsborn K, King E, Pratt J, Fichtenbaum CJ, Chougnet CA.

PLoS One. 2011;6(12):e28118. doi: 10.1371/journal.pone.0028118. Epub 2011 Dec 5.

43.

Myeloid dendritic cells isolated from tissues of SIV-infected Rhesus macaques promote the induction of regulatory T cells.

Presicce P, Shaw JM, Miller CJ, Shacklett BL, Chougnet CA.

AIDS. 2012 Jan 28;26(3):263-73. doi: 10.1097/QAD.0b013e32834ed8df.

44.

cAMP during HIV infection: friend or foe?

Moreno-Fernandez ME, Rueda CM, Velilla PA, Rugeles MT, Chougnet CA.

AIDS Res Hum Retroviruses. 2012 Jan;28(1):49-53. doi: 10.1089/AID.2011.0265. Epub 2011 Nov 2. Review.

45.

Highly active antiretroviral therapy in patients infected with human immunodeficiency virus increases CD40 ligand expression and IL-12 production in cells ex vivo.

Nyakeriga AM, Ying J, Shire NJ, Fichtenbaum CJ, Chougnet CA.

Viral Immunol. 2011 Aug;24(4):281-9. doi: 10.1089/vim.2010.0142.

46.

IL-1α mediated chorioamnionitis induces depletion of FoxP3+ cells and ileal inflammation in the ovine fetal gut.

Wolfs TG, Kallapur SG, Polglase GR, Pillow JJ, Nitsos I, Newnham JP, Chougnet CA, Kroon E, Spierings J, Willems CH, Jobe AH, Kramer BW.

PLoS One. 2011 Mar 29;6(3):e18355. doi: 10.1371/journal.pone.0018355.

47.

Regulatory T cells control HIV replication in activated T cells through a cAMP-dependent mechanism.

Moreno-Fernandez ME, Rueda CM, Rusie LK, Chougnet CA.

Blood. 2011 May 19;117(20):5372-80. doi: 10.1182/blood-2010-12-323162. Epub 2011 Mar 23.

48.

A major role for Bim in regulatory T cell homeostasis.

Chougnet CA, Tripathi P, Lages CS, Raynor J, Sholl A, Fink P, Plas DR, Hildeman DA.

J Immunol. 2011 Jan 1;186(1):156-63. doi: 10.4049/jimmunol.1001505. Epub 2010 Nov 22.

49.

Post-natal paucity of regulatory T cells and control of NK cell activation in experimental biliary atresia.

Miethke AG, Saxena V, Shivakumar P, Sabla GE, Simmons J, Chougnet CA.

J Hepatol. 2010 May;52(5):718-26. doi: 10.1016/j.jhep.2009.12.027. Epub 2010 Mar 5.

50.

Association of two clones allows for optimal detection of human FOXP3.

Presicce P, Moreno-Fernandez ME, Lages CS, Orsborn KI, Chougnet CA.

Cytometry A. 2010 Jun;77(6):571-9. doi: 10.1002/cyto.a.20875.

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