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Items: 6


Interspecies differences in the metabolism of methotrexate: An insight into the active site differences between human and rabbit aldehyde oxidase.

Choughule KV, Joswig-Jones CA, Jones JP.

Biochem Pharmacol. 2015 Aug 1;96(3):288-95. doi: 10.1016/j.bcp.2015.05.010. Epub 2015 May 29.


Characterization of bovine phenol sulfotransferases: evidence of a major role for SULT1B1 in the liver.

Choughule KV, Locuson CW, Coughtrie MW.

Xenobiotica. 2015;45(6):495-502. doi: 10.3109/00498254.2014.997325. Epub 2014 Dec 24.


In vitro oxidative metabolism of 6-mercaptopurine in human liver: insights into the role of the molybdoflavoenzymes aldehyde oxidase, xanthine oxidase, and xanthine dehydrogenase.

Choughule KV, Barnaba C, Joswig-Jones CA, Jones JP.

Drug Metab Dispos. 2014 Aug;42(8):1334-40. doi: 10.1124/dmd.114.058107. Epub 2014 May 13.


Why do most human liver cytosol preparations lack xanthine oxidase activity?

Barr JT, Choughule KV, Nepal S, Wong T, Chaudhry AS, Joswig-Jones CA, Zientek M, Strom SC, Schuetz EG, Thummel KE, Jones JP.

Drug Metab Dispos. 2014 Apr;42(4):695-9. doi: 10.1124/dmd.113.056374. Epub 2014 Jan 15.


Inhibition of xanthine oxidase by the aldehyde oxidase inhibitor raloxifene: implications for identifying molybdopterin nitrite reductases.

Weidert ER, Schoenborn SO, Cantu-Medellin N, Choughule KV, Jones JP, Kelley EE.

Nitric Oxide. 2014 Feb 15;37:41-5. doi: 10.1016/j.niox.2013.12.010. Epub 2014 Jan 7.


Evaluation of rhesus monkey and guinea pig hepatic cytosol fractions as models for human aldehyde oxidase.

Choughule KV, Barr JT, Jones JP.

Drug Metab Dispos. 2013 Oct;41(10):1852-8. doi: 10.1124/dmd.113.052985. Epub 2013 Aug 5.

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