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Items: 18

1.

Loss of Function of DOCK4 in Myelodysplastic Syndromes Stem Cells is Restored by Inhibitors of DOCK4 Signaling Networks.

Sundaravel S, Kuo WL, Jeong JJ, Choudhary GS, Gordon-Mitchell S, Liu H, Bhagat TD, McGraw KL, Gurbuxani S, List AF, Verma A, Wickrema A.

Clin Cancer Res. 2019 Sep 15;25(18):5638-5649. doi: 10.1158/1078-0432.CCR-19-0924. Epub 2019 Jul 15.

PMID:
31308061
2.

U2AF1 mutations induce oncogenic IRAK4 isoforms and activate innate immune pathways in myeloid malignancies.

Smith MA, Choudhary GS, Pellagatti A, Choi K, Bolanos LC, Bhagat TD, Gordon-Mitchell S, Von Ahrens D, Pradhan K, Steeples V, Kim S, Steidl U, Walter M, Fraser IDC, Kulkarni A, Salomonis N, Komurov K, Boultwood J, Verma A, Starczynowski DT.

Nat Cell Biol. 2019 May;21(5):640-650. doi: 10.1038/s41556-019-0314-5. Epub 2019 Apr 22.

3.

North American ATLL has a distinct mutational and transcriptional profile and responds to epigenetic therapies.

Shah UA, Chung EY, Giricz O, Pradhan K, Kataoka K, Gordon-Mitchell S, Bhagat TD, Mai Y, Wei Y, Ishida E, Choudhary GS, Joseph A, Rice R, Gitego N, Parrish C, Bartenstein M, Goel S, Mantzaris I, Shastri A, Derman O, Binder A, Gritsman K, Kornblum N, Braunschweig I, Bhagat C, Hall J, Graber A, Ratner L, Wang Y, Ogawa S, Verma A, Ye BH, Janakiram M.

Blood. 2018 Oct 4;132(14):1507-1518. doi: 10.1182/blood-2018-01-824607. Epub 2018 Aug 13.

PMID:
30104217
4.

Direct Activation of BAX by BTSA1 Overcomes Apoptosis Resistance in Acute Myeloid Leukemia.

Reyna DE, Garner TP, Lopez A, Kopp F, Choudhary GS, Sridharan A, Narayanagari SR, Mitchell K, Dong B, Bartholdy BA, Walensky LD, Verma A, Steidl U, Gavathiotis E.

Cancer Cell. 2017 Oct 9;32(4):490-505.e10. doi: 10.1016/j.ccell.2017.09.001.

5.

Upregulation of TET activity with ascorbic acid induces epigenetic modulation of lymphoma cells.

Shenoy N, Bhagat T, Nieves E, Stenson M, Lawson J, Choudhary GS, Habermann T, Nowakowski G, Singh R, Wu X, Verma A, Witzig TE.

Blood Cancer J. 2017 Jul 21;7(7):e587. doi: 10.1038/bcj.2017.65.

6.

Epigenetically Aberrant Stroma in MDS Propagates Disease via Wnt/β-Catenin Activation.

Bhagat TD, Chen S, Bartenstein M, Barlowe AT, Von Ahrens D, Choudhary GS, Tivnan P, Amin E, Marcondes AM, Sanders MA, Hoogenboezem RM, Kambhampati S, Ramachandra N, Mantzaris I, Sukrithan V, Laurence R, Lopez R, Bhagat P, Giricz O, Sohal D, Wickrema A, Yeung C, Gritsman K, Aplan P, Hochedlinger K, Yu Y, Pradhan K, Zhang J, Greally JM, Mukherjee S, Pellagatti A, Boultwood J, Will B, Steidl U, Raaijmakers MHGP, Deeg HJ, Kharas MG, Verma A.

Cancer Res. 2017 Sep 15;77(18):4846-4857. doi: 10.1158/0008-5472.CAN-17-0282. Epub 2017 Jul 6.

7.

Human Granulocyte Macrophage Colony-Stimulating Factor Enhances Antibiotic Susceptibility of Pseudomonas aeruginosa Persister Cells.

Choudhary GS, Yao X, Wang J, Peng B, Bader RA, Ren D.

Sci Rep. 2015 Nov 30;5:17315. doi: 10.1038/srep17315.

8.

miR-377-dependent BCL-xL regulation drives chemotherapeutic resistance in B-cell lymphoid malignancies.

Al-Harbi S, Choudhary GS, Ebron JS, Hill BT, Vivekanathan N, Ting AH, Radivoyevitch T, Smith MR, Shukla GC, Almasan A.

Mol Cancer. 2015 Nov 4;14:185. doi: 10.1186/s12943-015-0460-8.

9.

Cyclin E/Cdk2-dependent phosphorylation of Mcl-1 determines its stability and cellular sensitivity to BH3 mimetics.

Choudhary GS, Tat TT, Misra S, Hill BT, Smith MR, Almasan A, Mazumder S.

Oncotarget. 2015 Jul 10;6(19):16912-25.

10.

The TMPRSS2-ERG Gene Fusion Blocks XRCC4-Mediated Nonhomologous End-Joining Repair and Radiosensitizes Prostate Cancer Cells to PARP Inhibition.

Chatterjee P, Choudhary GS, Alswillah T, Xiong X, Heston WD, Magi-Galluzzi C, Zhang J, Klein EA, Almasan A.

Mol Cancer Ther. 2015 Aug;14(8):1896-906. doi: 10.1158/1535-7163.MCT-14-0865. Epub 2015 May 29.

11.

Signaling factor interactions with polysaccharide aggregates of bacterial biofilms.

DeSalvo SC, Liu Y, Choudhary GS, Ren D, Nangia S, Sureshkumar R.

Langmuir. 2015 Feb 17;31(6):1958-66. doi: 10.1021/la504721b. Epub 2015 Feb 3.

PMID:
25607640
12.

MCL-1 and BCL-xL-dependent resistance to the BCL-2 inhibitor ABT-199 can be overcome by preventing PI3K/AKT/mTOR activation in lymphoid malignancies.

Choudhary GS, Al-Harbi S, Mazumder S, Hill BT, Smith MR, Bodo J, Hsi ED, Almasan A.

Cell Death Dis. 2015 Jan 15;6:e1593. doi: 10.1038/cddis.2014.525.

13.

Caspase-3 activation is a critical determinant of genotoxic stress-induced apoptosis.

Choudhary GS, Al-Harbi S, Almasan A.

Methods Mol Biol. 2015;1219:1-9. doi: 10.1007/978-1-4939-1661-0_1.

PMID:
25308257
14.

PARP inhibition sensitizes to low dose-rate radiation TMPRSS2-ERG fusion gene-expressing and PTEN-deficient prostate cancer cells.

Chatterjee P, Choudhary GS, Sharma A, Singh K, Heston WD, Ciezki J, Klein EA, Almasan A.

PLoS One. 2013;8(4):e60408. doi: 10.1371/journal.pone.0060408. Epub 2013 Apr 2.

15.

Mcl-1 Phosphorylation defines ABT-737 resistance that can be overcome by increased NOXA expression in leukemic B cells.

Mazumder S, Choudhary GS, Al-Harbi S, Almasan A.

Cancer Res. 2012 Jun 15;72(12):3069-79. doi: 10.1158/0008-5472.CAN-11-4106. Epub 2012 Apr 23.

16.

Acidic stress promotes a glioma stem cell phenotype.

Hjelmeland AB, Wu Q, Heddleston JM, Choudhary GS, MacSwords J, Lathia JD, McLendon R, Lindner D, Sloan A, Rich JN.

Cell Death Differ. 2011 May;18(5):829-40. doi: 10.1038/cdd.2010.150. Epub 2010 Dec 3.

17.

Primary spinal pleomorphic xanthoastrocytoma.

Gill M, Pathak HC, Madan R, Bhattacharya S, Choudhary GS.

Neurol India. 2010 Sep-Oct;58(5):771-3. doi: 10.4103/0028-3886.72193.

18.

Dengue: A Clinicohaematological Profile.

Banerjee M, Chatterjee T, Choudhary GS, Srinivas V, Kataria VK.

Med J Armed Forces India. 2008 Oct;64(4):333-6. doi: 10.1016/S0377-1237(08)80014-7. Epub 2011 Jul 21.

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