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Items: 12

1.

In vivo kinetic approach reveals slow SOD1 turnover in the CNS.

Crisp MJ, Mawuenyega KG, Patterson BW, Reddy NC, Chott R, Self WK, Weihl CC, Jockel-Balsarotti J, Varadhachary AS, Bucelli RC, Yarasheski KE, Bateman RJ, Miller TM.

J Clin Invest. 2015 Jul 1;125(7):2772-80. doi: 10.1172/JCI80705. Epub 2015 Jun 15.

2.

Age and amyloid effects on human central nervous system amyloid-beta kinetics.

Patterson BW, Elbert DL, Mawuenyega KG, Kasten T, Ovod V, Ma S, Xiong C, Chott R, Yarasheski K, Sigurdson W, Zhang L, Goate A, Benzinger T, Morris JC, Holtzman D, Bateman RJ.

Ann Neurol. 2015 Sep;78(3):439-53. doi: 10.1002/ana.24454. Epub 2015 Jul 20.

3.

CNS amyloid-β, soluble APP-α and -β kinetics during BACE inhibition.

Dobrowolska JA, Michener MS, Wu G, Patterson BW, Chott R, Ovod V, Pyatkivskyy Y, Wildsmith KR, Kasten T, Mathers P, Dancho M, Lennox C, Smith BE, Gilberto D, McLoughlin D, Holder DJ, Stamford AW, Yarasheski KE, Kennedy ME, Savage MJ, Bateman RJ.

J Neurosci. 2014 Jun 11;34(24):8336-46. doi: 10.1523/JNEUROSCI.0540-14.2014.

4.

An antidepressant decreases CSF Aβ production in healthy individuals and in transgenic AD mice.

Sheline YI, West T, Yarasheski K, Swarm R, Jasielec MS, Fisher JR, Ficker WD, Yan P, Xiong C, Frederiksen C, Grzelak MV, Chott R, Bateman RJ, Morris JC, Mintun MA, Lee JM, Cirrito JR.

Sci Transl Med. 2014 May 14;6(236):236re4. doi: 10.1126/scitranslmed.3008169.

5.

Increased in vivo amyloid-β42 production, exchange, and loss in presenilin mutation carriers.

Potter R, Patterson BW, Elbert DL, Ovod V, Kasten T, Sigurdson W, Mawuenyega K, Blazey T, Goate A, Chott R, Yarasheski KE, Holtzman DM, Morris JC, Benzinger TL, Bateman RJ.

Sci Transl Med. 2013 Jun 12;5(189):189ra77. doi: 10.1126/scitranslmed.3005615.

6.

Gastric cancer in Zambian adults: a prospective case-control study that assessed dietary intake and antioxidant status by using urinary isoprostane excretion.

Asombang AW, Kayamba V, Mwanza-Lisulo M, Colditz G, Mudenda V, Yarasheski K, Chott R, Rubin DC, Gyawali CP, Sinkala E, Mwanamakondo S, Anderson-Spearie C, Kelly P.

Am J Clin Nutr. 2013 May;97(5):1029-35. doi: 10.3945/ajcn.112.051284. Epub 2013 Mar 27.

7.

Commitment to glycolysis sustains survival of NO-producing inflammatory dendritic cells.

Everts B, Amiel E, van der Windt GJ, Freitas TC, Chott R, Yarasheski KE, Pearce EL, Pearce EJ.

Blood. 2012 Aug 16;120(7):1422-31. doi: 10.1182/blood-2012-03-419747. Epub 2012 Jul 11.

8.

Parallel solid-phase synthesis and high-throughput 1H NMR evaluation of a 96-member 1,2,4-trisubstituted-pyrimidin-6-one-5-carboxylic acid library.

Hamper BC, Kesselring AS, Chott RC, Yang S.

J Comb Chem. 2009 May-Jun;11(3):469-80. doi: 10.1021/cc900010v.

PMID:
19296668
9.

Thiazolidinediones inhibit the progression of established hypertension in the Dahl salt-sensitive rat.

Bolten CW, Payne MA, McDonald WG, Blanner PM, Chott RC, Ghosh S, Arhancet GB, Staten NR, Gulve EA, Sullivan PM, Hromockyj AE, Colca JR.

Diab Vasc Dis Res. 2007 Jun;4(2):117-23.

PMID:
17654445
10.

Discovery of imidazole glycerol phosphate dehydratase inhibitors through 3-D database searching.

Schweitzer BA, Loida PJ, CaJacob CA, Chott RC, Collantes EM, Hegde SG, Mosier PD, Profeta S.

Bioorg Med Chem Lett. 2002 Jul 8;12(13):1743-6.

PMID:
12067551
11.

Synthesis of highly substituted 5-(trifluoromethyl)ketoimidazoles using a mixed-solid/solution phase motif.

Hamper BC, Jerome KD, Yalamanchili G, Walker DM, Chott RC, Mischke DA.

Biotechnol Bioeng. 2000 Winter;71(1):28-37.

PMID:
10629533

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