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Items: 1 to 50 of 759

1.

One- and two-year visual outcomes from the Moorfields age-related macular degeneration database: a retrospective cohort study and an open science resource.

Fasler K, Moraes G, Wagner S, Kortuem KU, Chopra R, Faes L, Preston G, Pontikos N, Fu DJ, Patel P, Tufail A, Lee AY, Balaskas K, Keane PA.

BMJ Open. 2019 Jun 21;9(6):e027441. doi: 10.1136/bmjopen-2018-027441.

2.

Identification and Characterization of Genes Involved in Field Pennycress (Thlaspi arvense L.) Glucosinolate Production (nzz047.OR20-06-19).

Ringling K, Chopra R, Anderson N, Marquart L, Marks MD.

Curr Dev Nutr. 2019 Jun 13;3(Suppl 1). pii: nzz047.OR2006-19. doi: 10.1093/cdn/nzz047.OR20-06-19. eCollection 2019 Jun.

3.

The photoperiodic flowering time regulator FKF1 negatively regulates cellulose biosynthesis.

Yuan N, Balasubramanian VK, Chopra R, Mendu V.

Plant Physiol. 2019 Jun 20. pii: pp.00013.2019. doi: 10.1104/pp.19.00013. [Epub ahead of print]

4.

Three-Year Outcomes of Biodegradable Polymer-Coated Ultra-Thin (60 µm) Sirolimus-Eluting Stents in Real-World Clinical Practice.

Chandwani P, Meel B, Singhal R, Jangid K, Ahmed R, Yadav M, Gupta AK, Chopra R.

Ann Acad Med Singapore. 2019 May;48(5):150-155.

5.

Placebo-responses in randomized controlled trials for systemic therapy in atopic dermatitis: a systematic review and meta-analysis.

Lee HH, Patel KR, Rastogi S, Singam V, Vakharia PP, Chopra R, Silverberg JI.

J Am Acad Dermatol. 2019 Jun 13. pii: S0190-9622(19)30970-3. doi: 10.1016/j.jaad.2019.05.102. [Epub ahead of print]

PMID:
31202874
6.

A critical evaluation of the approaches to targeted protein degradation for drug discovery.

Chopra R, Sadok A, Collins I.

Drug Discov Today Technol. 2019 Apr;31:5-13. doi: 10.1016/j.ddtec.2019.02.002. Epub 2019 Mar 6. Review.

7.

Comparison of Pain Perception Using Conventional Versus Computer-Controlled Intraligamentary Local Anesthetic Injection for Extraction of Primary Molars.

Mittal M, Chopra R, Kumar A, Srivastava D.

Anesth Prog. 2019 Summer;66(2):69-76. doi: 10.2344/anpr-66-01-09.

PMID:
31184941
8.

What would it cost to scale-up private sector engagement efforts for tuberculosis care? Evidence from three pilot programs in India.

Deo S, Jindal P, Gupta D, Khaparde S, Rade K, Sachdeva KS, Vadera B, Shah D, Patel K, Dave P, Chopra R, Jha N, Papineni S, Vijayan S, Dewan P.

PLoS One. 2019 Jun 5;14(6):e0214928. doi: 10.1371/journal.pone.0214928. eCollection 2019.

9.

Reply to 'Assembling the brain trust: the multidisciplinary imperative in neuro-oncology'.

Aldape K, Brindle KM, Chesler L, Chopra R, Gajjar A, Gilbert MR, Gottardo N, Gutmann DH, Hargrave D, Holland EC, Jones DTW, Joyce JA, Kearns P, Kieran MW, Mellinghoff IK, Merchant M, Pfister SM, Pollard SM, Ramaswamy V, Rich JN, Robinson GW, Rowitch DH, Sampson JH, Taylor MD, Workman P, Gilbertson RJ.

Nat Rev Clin Oncol. 2019 May 31. doi: 10.1038/s41571-019-0236-y. [Epub ahead of print] No abstract available.

PMID:
31150022
10.

The clinicians´ dilemma with mosaicism-an insight from inner cell mass biopsies.

Lawrenz B, El Khatib I, Liñán A, Bayram A, Arnanz A, Chopra R, De Munck N, Fatemi HM.

Hum Reprod. 2019 Jun 4;34(6):998-1010. doi: 10.1093/humrep/dez055.

PMID:
31114858
11.

Influence of Nanobubble Concentration on Blood-Brain Barrier Opening Using Focused Ultrasound Under Real-Time Acoustic Feedback Control.

Cheng B, Bing C, Xi Y, Shah B, Exner AA, Chopra R.

Ultrasound Med Biol. 2019 Aug;45(8):2174-2187. doi: 10.1016/j.ultrasmedbio.2019.03.016. Epub 2019 May 7.

12.

Cam-type femoroacetabular impingement-correlations between alpha angle versus volumetric measurements and surgical findings.

Dessouky R, Chhabra A, Zhang L, Gleason A, Chopra R, Chatzinoff Y, Fey NP, Xi Y, Wells J.

Eur Radiol. 2019 Jul;29(7):3431-3440. doi: 10.1007/s00330-018-5968-z. Epub 2019 Feb 11.

PMID:
30741344
13.

Challenges to curing primary brain tumours.

Aldape K, Brindle KM, Chesler L, Chopra R, Gajjar A, Gilbert MR, Gottardo N, Gutmann DH, Hargrave D, Holland EC, Jones DTW, Joyce JA, Kearns P, Kieran MW, Mellinghoff IK, Merchant M, Pfister SM, Pollard SM, Ramaswamy V, Rich JN, Robinson GW, Rowitch DH, Sampson JH, Taylor MD, Workman P, Gilbertson RJ.

Nat Rev Clin Oncol. 2019 Feb 7. doi: 10.1038/s41571-019-0177-5. [Epub ahead of print] Review.

PMID:
30733593
14.

Primary hydatidosis of distal femur masquerading malignancy -A rare case.

Dathik S, Chopra RK, Talwar J, Pheroz M, Prasad R.

J Clin Orthop Trauma. 2019 Jan-Feb;10(1):213-220. doi: 10.1016/j.jcot.2017.12.003. Epub 2017 Dec 12.

15.

Piezosurgery Versus Conventional Method Alveoloplasty.

Gangwani KD, Shetty L, Kulkarni D, Seshagiri R, Chopra R.

Ann Maxillofac Surg. 2018 Jul-Dec;8(2):181-187. doi: 10.4103/ams.ams_162_18.

16.

Marker Assisted Selection in Sorghum Using KASP Assay for the Detection of Single Nucleotide Polymorphism/Insertion Deletion.

Burow G, Chopra R, Hughes H, Xin Z, Burke J.

Methods Mol Biol. 2019;1931:75-84. doi: 10.1007/978-1-4939-9039-9_6.

PMID:
30652284
17.

Addressing Commentator Concerns on Methods in a Study of Strabismus Using Binocular Optical Coherence Tomography.

Chopra R, Anderson RS, Keane PA.

JAMA Ophthalmol. 2018 Dec 20. doi: 10.1001/jamaophthalmol.2018.6145. [Epub ahead of print] No abstract available.

PMID:
30570643
18.

Longer heating duration increases localized doxorubicin deposition and therapeutic index in Vx2 tumors using MR-HIFU mild hyperthermia and thermosensitive liposomal doxorubicin.

Bing C, Patel P, Staruch RM, Shaikh S, Nofiele J, Wodzak Staruch M, Szczepanski D, Williams NS, Laetsch T, Chopra R.

Int J Hyperthermia. 2019;36(1):196-203. doi: 10.1080/02656736.2018.1550815. Epub 2018 Dec 12.

PMID:
30541350
19.

MTSS1/Src family kinase dysregulation underlies multiple inherited ataxias.

Brown AS, Meera P, Altindag B, Chopra R, Perkins EM, Paul S, Scoles DR, Tarapore E, Magri J, Huang H, Jackson M, Shakkottai VG, Otis TS, Pulst SM, Atwood SX, Oro AE.

Proc Natl Acad Sci U S A. 2018 Dec 26;115(52):E12407-E12416. doi: 10.1073/pnas.1816177115. Epub 2018 Dec 7.

20.

The potent and selective cyclin-dependent kinases 4 and 6 inhibitor ribociclib (LEE011) is a versatile combination partner in preclinical cancer models.

Kim S, Tiedt R, Loo A, Horn T, Delach S, Kovats S, Haas K, Engstler BS, Cao A, Pinzon-Ortiz M, Mulford I, Acker MG, Chopra R, Brain C, di Tomaso E, Sellers WR, Caponigro G.

Oncotarget. 2018 Oct 16;9(81):35226-35240. doi: 10.18632/oncotarget.26215. eCollection 2018 Oct 16.

21.

Translational genomics using Arabidopsis as a model enables the characterization of pennycress genes through forward and reverse genetics.

Chopra R, Johnson EB, Daniels E, McGinn M, Dorn KM, Esfahanian M, Folstad N, Amundson K, Altendorf K, Betts K, Frels K, Anderson JA, Wyse DL, Sedbrook JC, David Marks M.

Plant J. 2018 Dec;96(6):1093-1105. doi: 10.1111/tpj.14147.

PMID:
30394623
22.

Structural reorganization of SHP2 by oncogenic mutations and implications for oncoprotein resistance to allosteric inhibition.

LaRochelle JR, Fodor M, Vemulapalli V, Mohseni M, Wang P, Stams T, LaMarche MJ, Chopra R, Acker MG, Blacklow SC.

Nat Commun. 2018 Oct 30;9(1):4508. doi: 10.1038/s41467-018-06823-9.

23.

Author Correction: Acylated-acyl carrier protein stabilizes the Pseudomonas aeruginosa WaaP lipopolysaccharide heptose kinase.

Kreamer NNK, Chopra R, Caughlan RE, Fabbro D, Fang E, Gee P, Hunt I, Li M, Leon BC, Muller L, Vash B, Woods AL, Stams T, Dean CR, Uehara T.

Sci Rep. 2018 Oct 23;8(1):15907. doi: 10.1038/s41598-018-34070-x.

24.

Assessment of isocenter alignment during CT colonography: Implications for clinical practice.

Olden KL, Kavanagh RG, James K, Twomey M, Moloney F, Moore N, Carey K, Murphy KP, Grey TM, Nicholson P, Chopra R, Maher MM, O'Connor OJ.

Radiography (Lond). 2018 Nov;24(4):334-339. doi: 10.1016/j.radi.2018.04.003. Epub 2018 Apr 26.

PMID:
30292502
25.

Measurement properties of three assessments of burden used in atopic dermatitis in adults.

Patel KR, Singam V, Vakharia PP, Chopra R, Sacotte R, Patel N, Immaneni S, Kantor R, Hsu DY, Silverberg JI.

Br J Dermatol. 2019 May;180(5):1083-1089. doi: 10.1111/bjd.17243. Epub 2018 Nov 12.

PMID:
30246360
26.

Acylated-acyl carrier protein stabilizes the Pseudomonas aeruginosa WaaP lipopolysaccharide heptose kinase.

Kreamer NNK, Chopra R, Caughlan RE, Fabbro D, Fang E, Gee P, Hunt I, Li M, Leon BC, Muller L, Vash B, Woods AL, Stams T, Dean CR, Uehara T.

Sci Rep. 2018 Sep 20;8(1):14124. doi: 10.1038/s41598-018-32379-1. Erratum in: Sci Rep. 2018 Oct 23;8(1):15907.

27.

Molecular tools enabling pennycress (Thlaspi arvense) as a model plant and oilseed cash cover crop.

McGinn M, Phippen WB, Chopra R, Bansal S, Jarvis BA, Phippen ME, Dorn KM, Esfahanian M, Nazarenus TJ, Cahoon EB, Durrett TP, Marks MD, Sedbrook JC.

Plant Biotechnol J. 2019 Apr;17(4):776-788. doi: 10.1111/pbi.13014. Epub 2018 Oct 25.

28.

Assessing the severity of atopic dermatitis in clinical trials and practice.

Chopra R, Silverberg JI.

Clin Dermatol. 2018 Sep - Oct;36(5):606-615. doi: 10.1016/j.clindermatol.2018.05.012. Epub 2018 Jun 1. Review.

PMID:
30217273
29.

Coordinate regulation of mutant NPC1 degradation by selective ER autophagy and MARCH6-dependent ERAD.

Schultz ML, Krus KL, Kaushik S, Dang D, Chopra R, Qi L, Shakkottai VG, Cuervo AM, Lieberman AP.

Nat Commun. 2018 Sep 10;9(1):3671. doi: 10.1038/s41467-018-06115-2.

30.

A First-in-Human Study of Novel Cereblon Modulator Avadomide (CC-122) in Advanced Malignancies.

Rasco DW, Papadopoulos KP, Pourdehnad M, Gandhi AK, Hagner PR, Li Y, Wei X, Chopra R, Hege K, DiMartino J, Shih K.

Clin Cancer Res. 2019 Jan 1;25(1):90-98. doi: 10.1158/1078-0432.CCR-18-1203. Epub 2018 Sep 10.

PMID:
30201761
31.

3D CT segmentation of CAM type femoroacetabular impingement-reliability and relationship of CAM lesion with anthropomorphic features.

Zhang L, Wells JE, Dessouky R, Gleason A, Chopra R, Chatzinoff Y, Fey NP, Xi Y, Chhabra A.

Br J Radiol. 2018 Dec;91(1092):20180371. doi: 10.1259/bjr.20180371. Epub 2018 Sep 12.

PMID:
30168728
32.

Clinical reassessment of human embryo ploidy status between cleavage and blastocyst stage by Next Generation Sequencing.

Liñán A, Lawrenz B, El Khatib I, Bayram A, Arnanz A, Rubio C, Chopra R, Fatemi HM.

PLoS One. 2018 Aug 22;13(8):e0201652. doi: 10.1371/journal.pone.0201652. eCollection 2018.

33.

Clinically applicable deep learning for diagnosis and referral in retinal disease.

De Fauw J, Ledsam JR, Romera-Paredes B, Nikolov S, Tomasev N, Blackwell S, Askham H, Glorot X, O'Donoghue B, Visentin D, van den Driessche G, Lakshminarayanan B, Meyer C, Mackinder F, Bouton S, Ayoub K, Chopra R, King D, Karthikesalingam A, Hughes CO, Raine R, Hughes J, Sim DA, Egan C, Tufail A, Montgomery H, Hassabis D, Rees G, Back T, Khaw PT, Suleyman M, Cornebise J, Keane PA, Ronneberger O.

Nat Med. 2018 Sep;24(9):1342-1350. doi: 10.1038/s41591-018-0107-6. Epub 2018 Aug 13.

PMID:
30104768
34.

Efficacy and Safety of Topical Cantharidin Treatment for Molluscum Contagiosum and Warts: A Systematic Review.

Vakharia PP, Chopra R, Silverberg NB, Silverberg JI.

Am J Clin Dermatol. 2018 Dec;19(6):791-803. doi: 10.1007/s40257-018-0375-4.

PMID:
30097988
35.

SNP genotyping reveals major QTLs for plant architectural traits between A-genome peanut wild species.

Chopra R, Simpson CE, Hillhouse A, Payton P, Sharma J, Burow MD.

Mol Genet Genomics. 2018 Dec;293(6):1477-1491. doi: 10.1007/s00438-018-1472-z. Epub 2018 Aug 1.

PMID:
30069598
36.

Multiparametric MRI Characterization of Funaki Types of Uterine Fibroids Considered for MR-Guided High-Intensity Focused Ultrasound (MR-HIFU) Therapy.

Andrews S, Yuan Q, Bailey A, Xi Y, Chopra R, Staruch R, Pedrosa I.

Acad Radiol. 2019 Apr;26(4):e9-e17. doi: 10.1016/j.acra.2018.05.012. Epub 2018 Jul 29.

PMID:
30064919
37.

Deep Learning for Predicting Refractive Error From Retinal Fundus Images.

Varadarajan AV, Poplin R, Blumer K, Angermueller C, Ledsam J, Chopra R, Keane PA, Corrado GS, Peng L, Webster DR.

Invest Ophthalmol Vis Sci. 2018 Jun 1;59(7):2861-2868. doi: 10.1167/iovs.18-23887.

PMID:
30025129
38.

Cereblon modulator iberdomide induces degradation of the transcription factors Ikaros and Aiolos: immunomodulation in healthy volunteers and relevance to systemic lupus erythematosus.

Schafer PH, Ye Y, Wu L, Kosek J, Ringheim G, Yang Z, Liu L, Thomas M, Palmisano M, Chopra R.

Ann Rheum Dis. 2018 Oct;77(10):1516-1523. doi: 10.1136/annrheumdis-2017-212916. Epub 2018 Jun 26.

39.

Oligonucleotide therapy mitigates disease in spinocerebellar ataxia type 3 mice.

McLoughlin HS, Moore LR, Chopra R, Komlo R, McKenzie M, Blumenstein KG, Zhao H, Kordasiewicz HB, Shakkottai VG, Paulson HL.

Ann Neurol. 2018 Jul;84(1):64-77. doi: 10.1002/ana.25264. Epub 2018 Aug 6.

PMID:
29908063
40.

Use of a Binocular Optical Coherence Tomography System to Evaluate Strabismus in Primary Position.

Chopra R, Mulholland PJ, Tailor VK, Anderson RS, Keane PA.

JAMA Ophthalmol. 2018 Jul 1;136(7):811-817. doi: 10.1001/jamaophthalmol.2018.1973.

41.

Dendritic potassium channel dysfunction may contribute to dendrite degeneration in spinocerebellar ataxia type 1.

Chopra R, Bushart DD, Shakkottai VG.

PLoS One. 2018 May 30;13(5):e0198040. doi: 10.1371/journal.pone.0198040. eCollection 2018.

42.

Characterization of different bubble formulations for blood-brain barrier opening using a focused ultrasound system with acoustic feedback control.

Bing C, Hong Y, Hernandez C, Rich M, Cheng B, Munaweera I, Szczepanski D, Xi Y, Bolding M, Exner A, Chopra R.

Sci Rep. 2018 May 22;8(1):7986. doi: 10.1038/s41598-018-26330-7.

43.

Remote acoustic sensing as a safety mechanism during exposure of metal implants to alternating magnetic fields.

Cheng B, Chatzinoff Y, Szczepanski D, Bing C, Shaikh S, Wyman O, Perry CE, Richardson JA, Burns DK, Evers BM, Greenberg DE, Chopra R.

PLoS One. 2018 May 10;13(5):e0197380. doi: 10.1371/journal.pone.0197380. eCollection 2018.

44.

Clinical characteristics and outcomes of patients with multiple simultaneous superficial vein thrombi.

Chopra R, Leon LR, Labropoulos N.

J Vasc Surg Venous Lymphat Disord. 2018 Jul;6(4):485-491. doi: 10.1016/j.jvsv.2018.01.011. Epub 2018 Apr 18.

PMID:
29678687
45.

In Vivo Degradation of Crosslinked Hyaluronic Acid Fillers by Exogenous Hyaluronidases.

Shumate GT, Chopra R, Jones D, Messina DJ, Hee CK.

Dermatol Surg. 2018 Aug;44(8):1075-1083. doi: 10.1097/DSS.0000000000001525.

PMID:
29659410
46.

Correcting B0 Field Distortions in MRI Caused by Stainless Steel Orthodontic Appliances at 1.5 T Using Permanent Magnets - A Head Phantom Study.

Wang ZJ, Park YJ, Morriss MC, Seo Y, Nguyen T, Hallac RR, Nava A, Chopra R, Chatzinoff Y, Price K, Rollins NK.

Sci Rep. 2018 Apr 9;8(1):5706. doi: 10.1038/s41598-018-23890-6.

47.

A review on phytochemistry and therapeutic uses of Hibiscus sabdariffa L.

Riaz G, Chopra R.

Biomed Pharmacother. 2018 Jun;102:575-586. doi: 10.1016/j.biopha.2018.03.023. Epub 2018 Apr 5. Review.

PMID:
29597091
48.

Targeting potassium channels to treat cerebellar ataxia.

Bushart DD, Chopra R, Singh V, Murphy GG, Wulff H, Shakkottai VG.

Ann Clin Transl Neurol. 2018 Jan 22;5(3):297-314. doi: 10.1002/acn3.527. eCollection 2018 Mar.

49.

Introduction to the special issue on thermal therapy and infectious diseases.

Chopra R, Levi-Polyachenko N, Smeltzer MS.

Int J Hyperthermia. 2018 Mar;34(2):133-134. doi: 10.1080/02656736.2018.1424947. No abstract available.

PMID:
29498313
50.

Temperature-sensitive liposomal ciprofloxacin for the treatment of biofilm on infected metal implants using alternating magnetic fields.

Munaweera I, Shaikh S, Maples D, Nigatu AS, Sethuraman SN, Ranjan A, Greenberg DE, Chopra R.

Int J Hyperthermia. 2018 Mar;34(2):189-200. doi: 10.1080/02656736.2017.1422028.

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