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Items: 1 to 50 of 231

1.

A Bacteriophage T4 Nanoparticle-Based Dual Vaccine against Anthrax and Plague.

Tao P, Mahalingam M, Zhu J, Moayeri M, Sha J, Lawrence WS, Leppla SH, Chopra AK, Rao VB.

MBio. 2018 Oct 16;9(5). pii: e01926-18. doi: 10.1128/mBio.01926-18.

2.

Assessment of plant growth attributes, bioaccumulation, enrichment, and translocation of heavy metals in water lettuce (Pistia stratiotes L.) grown in sugar mill effluent.

Kumar V, Singh J, Chopra AK.

Int J Phytoremediation. 2018 Apr 16;20(5):507-521. doi: 10.1080/15226514.2017.1393391.

PMID:
29608378
3.

Protection against inhalation anthrax by immunization with Salmonella enterica serovar Typhi Ty21a stably producing protective antigen of Bacillus anthracis.

Sim BKL, Li M, Osorio M, Wu Y, Wai TT, Peterson JW, James ER, Chakravarty S, Gao L, Xu R, Kc N, Stafford RE, Lawrence WS, Yeager LA, Peel JE, Sivasubramani SK, Chopra AK, Filippova S, Hoffman SL.

NPJ Vaccines. 2017 Jun 15;2:17. doi: 10.1038/s41541-017-0018-4. eCollection 2017.

4.

Combating Multidrug-Resistant Pathogens with Host-Directed Nonantibiotic Therapeutics.

Andersson JA, Sha J, Kirtley ML, Reyes E, Fitts EC, Dann SM, Chopra AK.

Antimicrob Agents Chemother. 2017 Dec 21;62(1). pii: e01943-17. doi: 10.1128/AAC.01943-17. Print 2018 Jan.

5.

Identification of New Virulence Factors and Vaccine Candidates for Yersinia pestis.

Andersson JA, Sha J, Erova TE, Fitts EC, Ponnusamy D, Kozlova EV, Kirtley ML, Chopra AK.

Front Cell Infect Microbiol. 2017 Oct 17;7:448. doi: 10.3389/fcimb.2017.00448. eCollection 2017.

6.

Assessment of phytokinetic removal of pollutants of paper mill effluent using water hyacinth (Eichhornia crassipes [Mart.] Solms).

Kumar V, Singh J, Chopra AK.

Environ Technol. 2018 Nov;39(21):2781-2791. doi: 10.1080/09593330.2017.1365944. Epub 2017 Aug 22.

PMID:
28793843
7.

A Bivalent Anthrax-Plague Vaccine That Can Protect against Two Tier-1 Bioterror Pathogens, Bacillus anthracis and Yersinia pestis.

Tao P, Mahalingam M, Zhu J, Moayeri M, Kirtley ML, Fitts EC, Andersson JA, Lawrence WS, Leppla SH, Chopra AK, Rao VB.

Front Immunol. 2017 Jun 26;8:687. doi: 10.3389/fimmu.2017.00687. eCollection 2017.

8.

Phytoremediation potential of water caltrop (Trapa natans L.) using municipal wastewater of the activated sludge process-based municipal wastewater treatment plant.

Kumar V, Chopra AK.

Environ Technol. 2018 Jan;39(1):12-23. doi: 10.1080/09593330.2017.1293165. Epub 2017 Feb 22.

PMID:
28278781
9.

Phospholipase A2-activating protein is associated with a novel form of leukoencephalopathy.

Falik Zaccai TC, Savitzki D, Zivony-Elboum Y, Vilboux T, Fitts EC, Shoval Y, Kalfon L, Samra N, Keren Z, Gross B, Chasnyk N, Straussberg R, Mullikin JC, Teer JK, Geiger D, Kornitzer D, Bitterman-Deutsch O, Samson AO, Wakamiya M, Peterson JW, Kirtley ML, Pinchuk IV, Baze WB, Gahl WA, Kleta R, Anikster Y, Chopra AK.

Brain. 2017 Feb;140(2):370-386. doi: 10.1093/brain/aww295. Epub 2016 Dec 21.

10.

New Insights into Autoinducer-2 Signaling as a Virulence Regulator in a Mouse Model of Pneumonic Plague.

Fitts EC, Andersson JA, Kirtley ML, Sha J, Erova TE, Chauhan S, Motin VL, Chopra AK.

mSphere. 2016 Dec 14;1(6). pii: e00342-16. eCollection 2016 Nov-Dec.

11.

Protective Immunity Elicited by Oral Immunization of Mice with Salmonella enterica Serovar Typhimurium Braun Lipoprotein (Lpp) and Acetyltransferase (MsbB) Mutants.

Erova TE, Kirtley ML, Fitts EC, Ponnusamy D, Baze WB, Andersson JA, Cong Y, Tiner BL, Sha J, Chopra AK.

Front Cell Infect Microbiol. 2016 Nov 10;6:148. eCollection 2016.

12.

Irrigating okra with secondary treated municipal wastewater: Observations regarding plant growth and soil characteristics.

Kumar V, Chopra AK, Srivastava S, Singh J, Thakur RK.

Int J Phytoremediation. 2017 May 4;19(5):490-499. doi: 10.1080/15226514.2016.1244169.

PMID:
27739866
13.

Chronic persistent post-surgical pain following staging laparotomy for carcinoma of ovary and its relationship to signal transduction genes.

Saxena AK, Chilkoti GT, Chopra AK, Banerjee BD, Sharma T.

Korean J Pain. 2016 Oct;29(4):239-248. Epub 2016 Sep 29.

14.

Immunisation of two rodent species with new live-attenuated mutants of Yersinia pestis CO92 induces protective long-term humoral- and cell-mediated immunity against pneumonic plague.

Tiner BL, Sha J, Cong Y, Kirtley ML, Andersson JA, Chopra AK.

NPJ Vaccines. 2016 Oct 13;1:16020. doi: 10.1038/npjvaccines.2016.20. eCollection 2016.

15.

A mutated cholera toxin without the ADP-ribosyltransferase activity induces cytokine production and inhibits apoptosis of splenocytes in mice possibly via toll-like receptor-4 signaling.

Liu T, Wei Y, Liu G, Shi B, Giovanni S, Peterson JW, Chopra AK.

Mol Immunol. 2016 Jul;75:21-7. doi: 10.1016/j.molimm.2016.05.005. Epub 2016 May 20.

16.

A Replication-Defective Human Type 5 Adenovirus-Based Trivalent Vaccine Confers Complete Protection against Plague in Mice and Nonhuman Primates.

Sha J, Kirtley ML, Klages C, Erova TE, Telepnev M, Ponnusamy D, Fitts EC, Baze WB, Sivasubramani SK, Lawrence WS, Patrikeev I, Peel JE, Andersson JA, Kozlova EV, Tiner BL, Peterson JW, McWilliams D, Patel S, Rothe E, Motin VL, Chopra AK.

Clin Vaccine Immunol. 2016 Jul 5;23(7):586-600. doi: 10.1128/CVI.00150-16. Print 2016 Jul.

17.

New Role for FDA-Approved Drugs in Combating Antibiotic-Resistant Bacteria.

Andersson JA, Fitts EC, Kirtley ML, Ponnusamy D, Peniche AG, Dann SM, Motin VL, Chauhan S, Rosenzweig JA, Sha J, Chopra AK.

Antimicrob Agents Chemother. 2016 May 23;60(6):3717-29. doi: 10.1128/AAC.00326-16. Print 2016 Jun.

18.

Cross-talk among flesh-eating Aeromonas hydrophila strains in mixed infection leading to necrotizing fasciitis.

Ponnusamy D, Kozlova EV, Sha J, Erova TE, Azar SR, Fitts EC, Kirtley ML, Tiner BL, Andersson JA, Grim CJ, Isom RP, Hasan NA, Colwell RR, Chopra AK.

Proc Natl Acad Sci U S A. 2016 Jan 19;113(3):722-7. doi: 10.1073/pnas.1523817113. Epub 2016 Jan 5.

19.

Paclitaxel-Eluting versus Everolimus-Eluting Coronary Stents in Diabetes.

Kaul U, Bangalore S, Seth A, Arambam P, Abhaichand RK, Patel TM, Banker D, Abhyankar A, Mullasari AS, Shah S, Jain R, Kumar PR, Bahuleyan CG; TUXEDO–India Investigators.

N Engl J Med. 2015 Oct 29;373(18):1709-19. doi: 10.1056/NEJMoa1510188. Epub 2015 Oct 14. Erratum in: N Engl J Med. 2016 Jul 28;375(4):398. Abhaychand, Rajpal K [Corrected to Abhaichand, Rajpal K].

20.

Intramuscular Immunization of Mice with a Live-Attenuated Triple Mutant of Yersinia pestis CO92 Induces Robust Humoral and Cell-Mediated Immunity To Completely Protect Animals against Pneumonic Plague.

Tiner BL, Sha J, Ponnusamy D, Baze WB, Fitts EC, Popov VL, van Lier CJ, Erova TE, Chopra AK.

Clin Vaccine Immunol. 2015 Dec;22(12):1255-68. doi: 10.1128/CVI.00499-15. Epub 2015 Oct 7.

21.

Experimental and kinetic studies for phycoremediation and dye removal by Chlorella pyrenoidosa from textile wastewater.

Pathak VV, Kothari R, Chopra AK, Singh DP.

J Environ Manage. 2015 Nov 1;163:270-7. doi: 10.1016/j.jenvman.2015.08.041. Epub 2015 Sep 5.

PMID:
26349408
22.

Accumulation of heavy metals in the vegetables grown in wastewater irrigated areas of Dehradun, India with reference to human health risk.

Chopra AK, Pathak C.

Environ Monit Assess. 2015 Jul;187(7):445. doi: 10.1007/s10661-015-4648-6. Epub 2015 Jun 20.

PMID:
26092239
23.

Development and evaluation of nanoemulsifying preconcentrate of curcumin for colon delivery.

Wadhwa J, Asthana A, Shilakari G, Chopra AK, Singh R.

ScientificWorldJournal. 2015;2015:541510. doi: 10.1155/2015/541510. Epub 2015 Mar 11.

24.

High-throughput, signature-tagged mutagenic approach to identify novel virulence factors of Yersinia pestis CO92 in a mouse model of infection.

Ponnusamy D, Fitts EC, Sha J, Erova TE, Kozlova EV, Kirtley ML, Tiner BL, Andersson JA, Chopra AK.

Infect Immun. 2015 May;83(5):2065-81. doi: 10.1128/IAI.02913-14. Epub 2015 Mar 9.

25.

Further characterization of a highly attenuated Yersinia pestis CO92 mutant deleted for the genes encoding Braun lipoprotein and plasminogen activator protease in murine alveolar and primary human macrophages.

van Lier CJ, Tiner BL, Chauhan S, Motin VL, Fitts EC, Huante MB, Endsley JJ, Ponnusamy D, Sha J, Chopra AK.

Microb Pathog. 2015 Mar;80:27-38. doi: 10.1016/j.micpath.2015.02.005. Epub 2015 Feb 16.

26.

Combinational deletion of three membrane protein-encoding genes highly attenuates yersinia pestis while retaining immunogenicity in a mouse model of pneumonic plague.

Tiner BL, Sha J, Kirtley ML, Erova TE, Popov VL, Baze WB, van Lier CJ, Ponnusamy D, Andersson JA, Motin VL, Chauhan S, Chopra AK.

Infect Immun. 2015 Apr;83(4):1318-38. doi: 10.1128/IAI.02778-14. Epub 2015 Jan 20.

27.

Phycoremediation of textile wastewater by unicellular microalga Chlorella pyrenoidosa.

Pathak VV, Singh DP, Kothari R, Chopra AK.

Cell Mol Biol (Noisy-le-grand). 2014 Dec 24;60(5):35-40.

PMID:
25535710
28.

Low-shear force associated with modeled microgravity and spaceflight does not similarly impact the virulence of notable bacterial pathogens.

Rosenzweig JA, Ahmed S, Eunson J Jr, Chopra AK.

Appl Microbiol Biotechnol. 2014 Nov;98(21):8797-807. doi: 10.1007/s00253-014-6025-8. Epub 2014 Aug 23. Review.

29.

Ferti-irrigational impact of sugar mill effluent on agronomical characteristics of Phaseolus vulgaris (L.) in two seasons.

Kumar V, Chopra AK.

Environ Monit Assess. 2014 Nov;186(11):7877-92. doi: 10.1007/s10661-014-3974-4. Epub 2014 Aug 8.

PMID:
25103211
30.

Tofacitinib versus methotrexate in rheumatoid arthritis.

Lee EB, Fleischmann R, Hall S, Wilkinson B, Bradley JD, Gruben D, Koncz T, Krishnaswami S, Wallenstein GV, Zang C, Zwillich SH, van Vollenhoven RF; ORAL Start Investigators.

N Engl J Med. 2014 Jun 19;370(25):2377-86. doi: 10.1056/NEJMoa1310476.

31.

Functional genomic characterization of virulence factors from necrotizing fasciitis-causing strains of Aeromonas hydrophila.

Grim CJ, Kozlova EV, Ponnusamy D, Fitts EC, Sha J, Kirtley ML, van Lier CJ, Tiner BL, Erova TE, Joseph SJ, Read TD, Shak JR, Joseph SW, Singletary E, Felland T, Baze WB, Horneman AJ, Chopra AK.

Appl Environ Microbiol. 2014 Jul;80(14):4162-83. doi: 10.1128/AEM.00486-14. Epub 2014 May 2.

32.

Deletion of Braun lipoprotein and plasminogen-activating protease-encoding genes attenuates Yersinia pestis in mouse models of bubonic and pneumonic plague.

van Lier CJ, Sha J, Kirtley ML, Cao A, Tiner BL, Erova TE, Cong Y, Kozlova EV, Popov VL, Baze WB, Chopra AK.

Infect Immun. 2014 Jun;82(6):2485-503. doi: 10.1128/IAI.01595-13. Epub 2014 Mar 31.

33.

Irrigational impact of distillery effluent on Abelmoschus esculentus L. Okra with special reference to heavy metals.

Srivastava S, Chopra AK.

Environ Monit Assess. 2014 Jul;186(7):4169-79. doi: 10.1007/s10661-014-3688-7. Epub 2014 Mar 19.

PMID:
24638936
34.
35.

The exoribonuclease Polynucleotide Phosphorylase influences the virulence and stress responses of yersiniae and many other pathogens.

Rosenzweig JA, Chopra AK.

Front Cell Infect Microbiol. 2013 Nov 19;3:81. doi: 10.3389/fcimb.2013.00081. eCollection 2013. Review.

36.

Modulation of host immune defenses by Aeromonas and Yersinia species: convergence on toxins secreted by various secretion systems.

Rosenzweig JA, Chopra AK.

Front Cell Infect Microbiol. 2013 Oct 30;3:70. doi: 10.3389/fcimb.2013.00070. eCollection 2013.

37.

Accumulation and translocation of metals in soil and different parts of French bean (Phaseolus vulgaris L.) amended with sewage sludge.

Kumar V, Chopra AK.

Bull Environ Contam Toxicol. 2014 Jan;92(1):103-8. doi: 10.1007/s00128-013-1142-0. Epub 2013 Nov 7.

PMID:
24196375
38.

The effects of modeled microgravity on growth kinetics, antibiotic susceptibility, cold growth, and the virulence potential of a Yersinia pestis ymoA-deficient mutant and its isogenic parental strain.

Lawal A, Kirtley ML, van Lier CJ, Erova TE, Kozlova EV, Sha J, Chopra AK, Rosenzweig JA.

Astrobiology. 2013 Sep;13(9):821-32. doi: 10.1089/ast.2013.0968. Epub 2013 Aug 29.

39.

Mutated and bacteriophage T4 nanoparticle arrayed F1-V immunogens from Yersinia pestis as next generation plague vaccines.

Tao P, Mahalingam M, Kirtley ML, van Lier CJ, Sha J, Yeager LA, Chopra AK, Rao VB.

PLoS Pathog. 2013;9(7):e1003495. doi: 10.1371/journal.ppat.1003495. Epub 2013 Jul 11.

40.

Characterization of Aeromonas hydrophila wound pathotypes by comparative genomic and functional analyses of virulence genes.

Grim CJ, Kozlova EV, Sha J, Fitts EC, van Lier CJ, Kirtley ML, Joseph SJ, Read TD, Burd EM, Tall BD, Joseph SW, Horneman AJ, Chopra AK, Shak JR.

MBio. 2013 Apr 23;4(2):e00064-13. doi: 10.1128/mBio.00064-13.

41.

In vitro and in vivo delivery of genes and proteins using the bacteriophage T4 DNA packaging machine.

Tao P, Mahalingam M, Marasa BS, Zhang Z, Chopra AK, Rao VB.

Proc Natl Acad Sci U S A. 2013 Apr 9;110(15):5846-51. doi: 10.1073/pnas.1300867110. Epub 2013 Mar 25.

42.

Evaluation of the roles played by Hcp and VgrG type 6 secretion system effectors in Aeromonas hydrophila SSU pathogenesis.

Sha J, Rosenzweig JA, Kozlova EV, Wang S, Erova TE, Kirtley ML, van Lier CJ, Chopra AK.

Microbiology. 2013 Jun;159(Pt 6):1120-35. doi: 10.1099/mic.0.063495-0. Epub 2013 Mar 21.

43.

Accumulation of heavy metals in Spinacia oleracea irrigated with paper mill effluent and sewage.

Pathak C, Chopra AK, Srivastava S.

Environ Monit Assess. 2013 Sep;185(9):7343-52. doi: 10.1007/s10661-013-3104-8. Epub 2013 Jan 31.

PMID:
23371250
44.

Tofacitinib (CP-690,550) in patients with rheumatoid arthritis receiving methotrexate: twelve-month data from a twenty-four-month phase III randomized radiographic study.

van der Heijde D, Tanaka Y, Fleischmann R, Keystone E, Kremer J, Zerbini C, Cardiel MH, Cohen S, Nash P, Song YW, Tegzová D, Wyman BT, Gruben D, Benda B, Wallenstein G, Krishnaswami S, Zwillich SH, Bradley JD, Connell CA; ORAL Scan Investigators.

Arthritis Rheum. 2013 Mar;65(3):559-70. doi: 10.1002/art.37816.

45.

WITHDRAWN: The majority of T cells, including Treg cells, are developed from CD4-CD8-T progenitor cells without the involvement of the CD4+CD8+ stage in the thymus.

Liu T, Huo X, Liu G, Chopra AK.

Dev Comp Immunol. 2013 Jan 17. pii: S0145-305X(13)00003-7. doi: 10.1016/j.dci.2012.12.007. [Epub ahead of print]

PMID:
23333732
46.

Deletion of the Braun lipoprotein-encoding gene and altering the function of lipopolysaccharide attenuate the plague bacterium.

Sha J, Kirtley ML, van Lier CJ, Wang S, Erova TE, Kozlova EV, Cao A, Cong Y, Fitts EC, Rosenzweig JA, Chopra AK.

Infect Immun. 2013 Mar;81(3):815-28. doi: 10.1128/IAI.01067-12. Epub 2012 Dec 28.

47.

Agro-potentiality of distillery effluent on soil and agronomical characteristics of Abelmoschus esculentus L. (okra).

Chopra AK, Srivastava S, Kumar V, Pathak C.

Environ Monit Assess. 2013 Aug;185(8):6635-44. doi: 10.1007/s10661-012-3052-8. Epub 2012 Dec 21.

PMID:
23264061
48.

Evaluation of protective potential of Yersinia pestis outer membrane protein antigens as possible candidates for a new-generation recombinant plague vaccine.

Erova TE, Rosenzweig JA, Sha J, Suarez G, Sierra JC, Kirtley ML, van Lier CJ, Telepnev MV, Motin VL, Chopra AK.

Clin Vaccine Immunol. 2013 Feb;20(2):227-38. doi: 10.1128/CVI.00597-12. Epub 2012 Dec 12.

49.

A non-invasive in vivo imaging system to study dissemination of bioluminescent Yersinia pestis CO92 in a mouse model of pneumonic plague.

Sha J, Rosenzweig JA, Kirtley ML, van Lier CJ, Fitts EC, Kozlova EV, Erova TE, Tiner BL, Chopra AK.

Microb Pathog. 2013 Feb;55:39-50. doi: 10.1016/j.micpath.2012.09.011. Epub 2012 Oct 9.

50.

Characterization of an actin-targeting ADP-ribosyltransferase from Aeromonas hydrophila.

Shniffer A, Visschedyk DD, Ravulapalli R, Suarez G, Turgeon ZJ, Petrie AA, Chopra AK, Merrill AR.

J Biol Chem. 2012 Oct 26;287(44):37030-41. doi: 10.1074/jbc.M112.397612. Epub 2012 Sep 11.

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