Sort by
Items per page

Send to

Choose Destination

Search results

Items: 17


ASLAN003, a potent dihydroorotate dehydrogenase inhibitor for differentiation of acute myeloid leukemia.

Zhou J, Quah JY, Ng Y, Chooi JY, Toh SH, Lin B, Tan TZ, Hosoi H, Osato M, Seet Q, Ooi AGL, Lindmark B, McHale M, Chng WJ.

Haematologica. 2019 Nov 7. pii: haematol.2019.230482. doi: 10.3324/haematol.2019.230482. [Epub ahead of print]


IL6 Promotes a STAT3-PRL3 Feedforward Loop via SHP2 Repression in Multiple Myeloma.

Chong PSY, Zhou J, Lim JSL, Hee YT, Chooi JY, Chung TH, Tan ZT, Zeng Q, Waller DD, Sebag M, Chng WJ.

Cancer Res. 2019 Sep 15;79(18):4679-4688. doi: 10.1158/0008-5472.CAN-19-0343. Epub 2019 Jul 23.


MMSET I acts as an oncoprotein and regulates GLO1 expression in t(4;14) multiple myeloma cells.

Xie Z, Chooi JY, Toh SHM, Yang D, Basri NB, Ho YS, Chng WJ.

Leukemia. 2019 Mar;33(3):739-748. doi: 10.1038/s41375-018-0300-0. Epub 2018 Nov 23.


Non-canonical activation of β-catenin by PRL-3 phosphatase in acute myeloid leukemia.

Chong PSY, Zhou J, Chooi JY, Chan ZL, Toh SHM, Tan TZ, Wee S, Gunaratne J, Zeng Q, Chng WJ.

Oncogene. 2019 Feb;38(9):1508-1519. doi: 10.1038/s41388-018-0526-3. Epub 2018 Oct 10.


Early morbidity associated with fasciotomies for acute compartment syndrome in children.

Lim KBL, Laine T, Chooi JY, Lye WK, Lee BJY, Narayanan UG.

J Child Orthop. 2018 Oct 1;12(5):480-487. doi: 10.1302/1863-2548.12.180049.


Aberrant hyperediting of the myeloma transcriptome by ADAR1 confers oncogenicity and is a marker of poor prognosis.

Teoh PJ, An O, Chung TH, Chooi JY, Toh SHM, Fan S, Wang W, Koh BTH, Fullwood MJ, Ooi MG, de Mel S, Soekojo CY, Chen L, Ng SB, Yang H, Chng WJ.

Blood. 2018 Sep 20;132(12):1304-1317. doi: 10.1182/blood-2018-02-832576. Epub 2018 Jul 30.


NF-κB promotes the stem-like properties of leukemia cells by activation of LIN28B.

Zhou J, Chooi JY, Ching YQ, Quah JY, Toh SH, Ng Y, Tan TZ, Chng WJ.

World J Stem Cells. 2018 Apr 26;10(4):34-42. doi: 10.4252/wjsc.v10.i4.34.


A loss-of-function genetic screening reveals synergistic targeting of AKT/mTOR and WTN/β-catenin pathways for treatment of AML with high PRL-3 phosphatase.

Zhou J, Toh SH, Chan ZL, Quah JY, Chooi JY, Tan TZ, Chong PSY, Zeng Q, Chng WJ.

J Hematol Oncol. 2018 Mar 7;11(1):36. doi: 10.1186/s13045-018-0581-9.


Inhibition of LIN28B impairs leukemia cell growth and metabolism in acute myeloid leukemia.

Zhou J, Bi C, Ching YQ, Chooi JY, Lu X, Quah JY, Toh SH, Chan ZL, Tan TZ, Chong PS, Chng WJ.

J Hematol Oncol. 2017 Jul 11;10(1):138. doi: 10.1186/s13045-017-0507-y.


LIN28B Activation by PRL-3 Promotes Leukemogenesis and a Stem Cell-like Transcriptional Program in AML.

Zhou J, Chan ZL, Bi C, Lu X, Chong PS, Chooi JY, Cheong LL, Liu SC, Ching YQ, Zhou Y, Osato M, Tan TZ, Ng CH, Ng SB, Wang S, Zeng Q, Chng WJ.

Mol Cancer Res. 2017 Mar;15(3):294-303. doi: 10.1158/1541-7786.MCR-16-0275-T. Epub 2016 Dec 23.


PRIMA-1met (APR-246) inhibits growth of colorectal cancer cells with different p53 status through distinct mechanisms.

Li XL, Zhou J, Chan ZL, Chooi JY, Chen ZR, Chng WJ.

Oncotarget. 2015 Nov 3;6(34):36689-99. doi: 10.18632/oncotarget.5385.


MMSET regulates expression of IRF4 in t(4;14) myeloma and its silencing potentiates the effect of bortezomib.

Xie Z, Bi C, Chooi JY, Chan ZL, Mustafa N, Chng WJ.

Leukemia. 2015 Dec;29(12):2347-54. doi: 10.1038/leu.2015.169. Epub 2015 Jun 30.


Cbfb deficiency results in differentiation blocks and stem/progenitor cell expansion in hematopoiesis.

Wang CQ, Chin DW, Chooi JY, Chng WJ, Taniuchi I, Tergaonkar V, Osato M.

Leukemia. 2015 Mar;29(3):753-7. doi: 10.1038/leu.2014.316. Epub 2014 Nov 5. No abstract available.


Disruption of Runx1 and Runx3 leads to bone marrow failure and leukemia predisposition due to transcriptional and DNA repair defects.

Wang CQ, Krishnan V, Tay LS, Chin DW, Koh CP, Chooi JY, Nah GS, Du L, Jacob B, Yamashita N, Lai SK, Tan TZ, Mori S, Tanuichi I, Tergaonkar V, Ito Y, Osato M.

Cell Rep. 2014 Aug 7;8(3):767-82. doi: 10.1016/j.celrep.2014.06.046. Epub 2014 Jul 24.


Quantum dot-based thermal spectroscopy and imaging of optically trapped microspheres and single cells.

Haro-González P, Ramsay WT, Martinez Maestro L, del Rosal B, Santacruz-Gomez K, Iglesias-de la Cruz Mdel C, Sanz-Rodríguez F, Chooi JY, Rodriguez Sevilla P, Bettinelli M, Choudhury D, Kar AK, Solé JG, Jaque D, Paterson L.

Small. 2013 Jun 24;9(12):2162-70. doi: 10.1002/smll.201201740. Epub 2013 Feb 11.


A man with a purple leg.

Ngu L, Chooi J, Harmse D, Thomas DW, Davies M.

Clin Exp Dermatol. 2009 Jan;34(1):123-4. doi: 10.1111/j.1365-2230.2007.02537.x. No abstract available.


Small bowel permeability--a variable effect of NSAIDS.

Choi VM, Coates JE, Chooi J, Thomson AB, Russell AS.

Clin Invest Med. 1995 Oct;18(5):357-61.


Supplemental Content

Support Center