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Items: 1 to 50 of 82

1.

Nanomedicines - Tiny particles and big challenges.

Marques MRC, Choo Q, Ashtikar M, Rocha TC, Bremer-Hoffmann S, Wacker MG.

Adv Drug Deliv Rev. 2019 Jun 19. pii: S0169-409X(19)30066-3. doi: 10.1016/j.addr.2019.06.003. [Epub ahead of print]

PMID:
31226397
2.

Pro-atherogenic proteoglycanase ADAMTS-1 is down-regulated by lauric acid through PI3K and JNK signaling pathways in THP-1 derived macrophages.

Ong MH, Wong HK, Tengku-Muhammad TS, Choo QC, Chew CH.

Mol Biol Rep. 2019 Jun;46(3):2631-2641. doi: 10.1007/s11033-019-04661-6. Epub 2019 Apr 15.

PMID:
30989556
3.

Quantitative analysis of local bone graft harvested from the posterior elements during posterior spinal fusion in Adolescent Idiopathic Scoliosis patients.

Choo QQ, Chiu CK, Lisitha KA, Chan CYW, Kwan MK.

J Orthop. 2018 Dec 21;16(1):74-79. doi: 10.1016/j.jor.2018.12.004. eCollection 2019 Jan-Feb.

PMID:
30662243
4.

Pharmacokinetic and Pharmacodynamic Evaluation of Different PEGylated Human Interleukin-11 Preparations in Animal Models.

Yu KM, Yiu-Nam Lau J, Fok M, Yeung YK, Fok SP, Hu TL, Tsai YJ, Choo QL.

J Pharm Sci. 2018 Nov;107(11):2755-2763. doi: 10.1016/j.xphs.2018.06.024. Epub 2018 Jul 10.

PMID:
30005986
5.

Let's Talk About B: Barriers to Hepatitis B Screening and Vaccination Among Asian and South Asian Immigrants in British Columbia.

Zibrik L, Huang A, Wong V, Novak Lauscher H, Choo Q, Yoshida EM, Ho K.

J Racial Ethn Health Disparities. 2018 Dec;5(6):1337-1345. doi: 10.1007/s40615-018-0483-0. Epub 2018 Mar 19.

PMID:
29557047
6.

Efficient expression and isolation of recombinant human interleukin-11 (rhIL-11) in Pichia pastoris.

Yu KM, Yiu-Nam Lau J, Fok M, Yeung YK, Fok SP, Shek F, Wong WT, Choo QL.

Protein Expr Purif. 2018 Jun;146:69-77. doi: 10.1016/j.pep.2018.01.012. Epub 2018 Feb 3.

PMID:
29408294
7.

Preclinical evaluation of the mono-PEGylated recombinant human interleukin-11 in cynomolgus monkeys.

Yu KM, Lau JY, Fok M, Yeung YK, Fok SP, Zhang S, Ye P, Zhang K, Li X, Li J, Xu Q, Wong WT, Choo QL.

Toxicol Appl Pharmacol. 2018 Mar 1;342:39-49. doi: 10.1016/j.taap.2018.01.016. Epub 2018 Feb 2.

PMID:
29407773
8.

Hepatitis B Awareness and Knowledge in Asian Communities in British Columbia.

Yau AH, Ford JA, Kwan PW, Chan J, Choo Q, Lee TK, Kwong W, Huang A, Yoshida E.

Can J Gastroenterol Hepatol. 2016;2016:4278724. doi: 10.1155/2016/4278724. Epub 2016 Mar 29.

10.

A Scoping Literature Review: The State of Knowledge on Home Care Equipment and Supplies.

Fraser KD, Lai J, Nissen C, Choo Q, Davenport J, Gutscher A.

Care Manag J. 2015;16(4):174-83. doi: 10.1891/1521-0987.16.4.174. Review.

PMID:
26673912
11.

The emergency to home project: impact of an emergency department care coordinator on hospital admission and emergency department utilization among seniors.

Bond CM, Freiheit EA, Podruzny L, Kingsly AA, Wang D, Davenport J, Gutscher A, Askin C, Taylor A, Lee V, Choo Q, Lang ES.

Int J Emerg Med. 2014 May 7;7:18. doi: 10.1186/1865-1380-7-18. eCollection 2014.

13.

New integron gene arrays from multiresistant clinical isolates of members of the Enterobacteriaceae and Pseudomonas aeruginosa from hospitals in Malaysia.

Kor SB, Choo QC, Chew CH.

J Med Microbiol. 2013 Mar;62(Pt 3):412-20. doi: 10.1099/jmm.0.053645-0. Epub 2012 Nov 22.

PMID:
23180481
14.

Tumour necrosis factor alpha down-regulates the expression of peroxisome proliferator activated receptor alpha (PPARα) in human hepatocarcinoma HepG2 cells by activation of NF-κB pathway.

Lim WS, Ng DL, Kor SB, Wong HK, Tengku-Muhammad TS, Choo QC, Chew CH.

Cytokine. 2013 Jan;61(1):266-74. doi: 10.1016/j.cyto.2012.10.007. Epub 2012 Nov 8. Erratum in: Cytokine. 2013 Feb;61(2):691.

PMID:
23141142
15.
16.

Determination of Z-3,5,4'-trimethoxystilbene in rat plasma by a simple HPLC method: application in a pre-clinical pharmacokinetic study.

Lin HS, Zhang W, Go ML, Choo QY, Ho PC.

J Pharm Biomed Anal. 2010 Nov 2;53(3):693-7. doi: 10.1016/j.jpba.2010.03.028. Epub 2010 Mar 27.

PMID:
20427141
17.
18.

Histone deacetylase inhibitors: new hope for rheumatoid arthritis?

Choo QY, Ho PC, Lin HS.

Curr Pharm Des. 2008;14(8):803-20. Review.

PMID:
18393882
19.

Synthesis and characterization of a native, oligomeric form of recombinant severe acute respiratory syndrome coronavirus spike glycoprotein.

Song HC, Seo MY, Stadler K, Yoo BJ, Choo QL, Coates SR, Uematsu Y, Harada T, Greer CE, Polo JM, Pileri P, Eickmann M, Rappuoli R, Abrignani S, Houghton M, Han JH.

J Virol. 2004 Oct;78(19):10328-35.

20.

Phylogeny and characterization of three nifH-homologous genes from Paenibacillus azotofixans.

Choo QC, Samian MR, Najimudin N.

Appl Environ Microbiol. 2003 Jun;69(6):3658-62.

21.

Activation of the grp78 and grp94 promoters by hepatitis C virus E2 envelope protein.

Liberman E, Fong YL, Selby MJ, Choo QL, Cousens L, Houghton M, Yen TS.

J Virol. 1999 May;73(5):3718-22.

22.

A quantitative test to estimate neutralizing antibodies to the hepatitis C virus: cytofluorimetric assessment of envelope glycoprotein 2 binding to target cells.

Rosa D, Campagnoli S, Moretto C, Guenzi E, Cousens L, Chin M, Dong C, Weiner AJ, Lau JY, Choo QL, Chien D, Pileri P, Houghton M, Abrignani S.

Proc Natl Acad Sci U S A. 1996 Mar 5;93(5):1759-63.

23.

HLA class I-restricted cytotoxic T lymphocytes specific for hepatitis C virus. Identification of multiple epitopes and characterization of patterns of cytokine release.

Koziel MJ, Dudley D, Afdhal N, Grakoui A, Rice CM, Choo QL, Houghton M, Walker BD.

J Clin Invest. 1995 Nov;96(5):2311-21.

24.

Prospects for prophylactic and therapeutic hepatitis C virus vaccines.

Houghton M, Choo QL, Kuo G, Weiner A, Chien D, Ralston R, Urdea M, Moss B, Purcell R, Cummins L, et al.

Princess Takamatsu Symp. 1995;25:237-43. Review. No abstract available.

PMID:
8875629
25.

Peptide immunogen mimicry of putative E1 glycoprotein-specific epitopes in hepatitis C virus.

Ray R, Khanna A, Lagging LM, Meyer K, Choo QL, Ralston R, Houghton M, Becherer PR.

J Virol. 1994 Jul;68(7):4420-6. Erratum in: J Virol 1994 Sep;68(9):6136.

26.

Vaccination of chimpanzees against infection by the hepatitis C virus.

Choo QL, Kuo G, Ralston R, Weiner A, Chien D, Van Nest G, Han J, Berger K, Thudium K, Kuo C, et al.

Proc Natl Acad Sci U S A. 1994 Feb 15;91(4):1294-8.

27.

Hepatitis C virus: structure, protein products and processing of the polyprotein precursor.

Houghton M, Selby M, Weiner A, Choo QL.

Curr Stud Hematol Blood Transfus. 1994;(61):1-11. Review. No abstract available.

PMID:
7956324
28.

Hepatitis C virus (HCV)-specific cytotoxic T lymphocytes recognize epitopes in the core and envelope proteins of HCV.

Koziel MJ, Dudley D, Afdhal N, Choo QL, Houghton M, Ralston R, Walker BD.

J Virol. 1993 Dec;67(12):7522-32.

29.

Characterization of hepatitis C virus envelope glycoprotein complexes expressed by recombinant vaccinia viruses.

Ralston R, Thudium K, Berger K, Kuo C, Gervase B, Hall J, Selby M, Kuo G, Houghton M, Choo QL.

J Virol. 1993 Nov;67(11):6753-61.

30.

Hepatitis C virus-specific CTL responses in the liver of chimpanzees with acute and chronic hepatitis C.

Erickson AL, Houghton M, Choo QL, Weiner AJ, Ralston R, Muchmore E, Walker CM.

J Immunol. 1993 Oct 15;151(8):4189-99.

PMID:
7691940
31.

Persistence of HCV despite antibodies to both putative envelope glycoproteins.

Chien DY, Choo QL, Ralston R, Spaete R, Tong M, Houghton M, Kuo G.

Lancet. 1993 Oct 9;342(8876):933. No abstract available.

PMID:
7692197
32.

Antibody response to core, envelope and nonstructural hepatitis C virus antigens: comparison of immunocompetent and immunosuppressed patients.

Lok AS, Chien D, Choo QL, Chan TM, Chiu EK, Cheng IK, Houghton M, Kuo G.

Hepatology. 1993 Sep;18(3):497-502.

PMID:
7689528
33.

Expression, identification and subcellular localization of the proteins encoded by the hepatitis C viral genome.

Selby MJ, Choo QL, Berger K, Kuo G, Glazer E, Eckart M, Lee C, Chien D, Kuo C, Houghton M.

J Gen Virol. 1993 Jun;74 ( Pt 6):1103-13.

PMID:
8389800
34.

The hepatitis C virus encodes a serine protease involved in processing of the putative nonstructural proteins from the viral polyprotein precursor.

Eckart MR, Selby M, Masiarz F, Lee C, Berger K, Crawford K, Kuo C, Kuo G, Houghton M, Choo QL.

Biochem Biophys Res Commun. 1993 Apr 30;192(2):399-406.

PMID:
8387277
35.

T-lymphocyte response to hepatitis C virus in different clinical courses of infection.

Botarelli P, Brunetto MR, Minutello MA, Calvo P, Unutmaz D, Weiner AJ, Choo QL, Shuster JR, Kuo G, Bonino F, et al.

Gastroenterology. 1993 Feb;104(2):580-7.

PMID:
8425701
36.

Towards a vaccine for the prevention of hepatitis delta virus superinfection in HBV carriers.

Ponzetto A, Eckart M, D'Urso N, Negro F, Silvestro M, Bonino F, Wang KS, Chien D, Choo QL, Houghton M.

Prog Clin Biol Res. 1993;382:207-10. No abstract available.

PMID:
8502681
37.

Diagnosis of hepatitis C virus (HCV) infection using an immunodominant chimeric polyprotein to capture circulating antibodies: reevaluation of the role of HCV in liver disease.

Chien DY, Choo QL, Tabrizi A, Kuo C, McFarland J, Berger K, Lee C, Shuster JR, Nguyen T, Moyer DL, et al.

Proc Natl Acad Sci U S A. 1992 Nov 1;89(21):10011-5.

38.

Hepatitis C virus antigen in hepatocytes: immunomorphologic detection and identification.

Krawczynski K, Beach MJ, Bradley DW, Kuo G, di Bisceglie AM, Houghton M, Reyes GR, Kim JP, Choo QL, Alter MJ.

Gastroenterology. 1992 Aug;103(2):622-9.

PMID:
1378804
39.

Identification of the major, parenteral non-A, non-B hepatitis agent (hepatitis C virus) using a recombinant cDNA approach.

Choo QL, Kuo G, Weiner A, Wang KS, Overby L, Bradley D, Houghton M.

Semin Liver Dis. 1992 Aug;12(3):279-88. Review. No abstract available.

PMID:
1332193
40.

Characterization of the hepatitis C virus E2/NS1 gene product expressed in mammalian cells.

Spaete RR, Alexander D, Rugroden ME, Choo QL, Berger K, Crawford K, Kuo C, Leng S, Lee C, Ralston R, et al.

Virology. 1992 Jun;188(2):819-30.

PMID:
1316682
41.

Enhanced sensitivity of a second generation ELISA for antibody to hepatitis C virus.

Bresters D, Cuypers HT, Reesink HW, Schaasberg WP, van der Poel CL, Mauser-Bunschoten EP, Houghton M, Choo QL, Kuo G, Lesniewski R, et al.

Vox Sang. 1992;62(4):213-7.

PMID:
1379394
42.

Early antihepatitis C virus response with second-generation C200/C22 ELISA.

van der Poel CL, Bresters D, Reesink HW, Plaisier AA, Schaasberg W, Leentvaar-Kuypers A, Choo QL, Quan S, Polito A, Houghton M, et al.

Vox Sang. 1992;62(4):208-12.

PMID:
1322611
43.

Elevated serum alanine aminotransferase levels in blood donors: the contribution of hepatitis C virus.

Katkov WN, Friedman LS, Cody H, Evans A, Kuo G, Choo QL, Houghton M, Dienstag JL.

Ann Intern Med. 1991 Dec 1;115(11):882-4. No abstract available.

PMID:
1952477
44.

Hepatitis C virus replication in 'autoimmune' chronic hepatitis.

Magrin S, Craxi A, Fabiano C, Fiorentino G, Almasio P, Palazzo U, Pinzello G, Provenzano G, Pagliaro L, Choo QL, et al.

J Hepatol. 1991 Nov;13(3):364-7.

PMID:
1725529
45.

Use of a signature nucleotide sequence of hepatitis C virus for detection of viral RNA in human serum and plasma.

Cha TA, Kolberg J, Irvine B, Stempien M, Beall E, Yano M, Choo QL, Houghton M, Kuo G, Han JH, et al.

J Clin Microbiol. 1991 Nov;29(11):2528-34.

46.

Risk factors in hepatitis C virus-infected blood donors.

van der Poel C, Cuypers H, Reesink H, Choo QL, Kuo G, Han J, Quan S, Polito A, Verstraten J, van de Wouw J, et al.

Transfusion. 1991 Oct;31(8):777-9.

PMID:
1926325
47.

Hepatitis C virus antibodies in acute icteric and chronic non-A, non-B hepatitis.

McHutchison JG, Kuo G, Houghton M, Choo QL, Redeker AG.

Gastroenterology. 1991 Oct;101(4):1117-9.

PMID:
1653749
48.

Role of hepatitis C virus in non-B chronic liver disease.

Katkov WN, Dienstag JL, Cody H, Evans AA, Choo QL, Houghton M, Kuo G.

Arch Intern Med. 1991 Aug;151(8):1548-52.

PMID:
1651689
49.

Molecular biology of the hepatitis C viruses: implications for diagnosis, development and control of viral disease.

Houghton M, Weiner A, Han J, Kuo G, Choo QL.

Hepatology. 1991 Aug;14(2):381-8. Review. No abstract available.

PMID:
1650328
50.

Antibody to the hepatitis C virus in acute hepatitis and chronic liver diseases in Japan.

Nishioka K, Watanabe J, Furuta S, Tanaka E, Suzuki H, Iino S, Tsuji T, Yano M, Kuo G, Choo QL, et al.

Liver. 1991 Apr;11(2):65-70.

PMID:
1646928

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