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Items: 1 to 50 of 200

1.

Megabase Length Hypermutation Accompanies Human Structural Variation at 17p11.2.

Beck CR, Carvalho CMB, Akdemir ZC, Sedlazeck FJ, Song X, Meng Q, Hu J, Doddapaneni H, Chong Z, Chen ES, Thornton PC, Liu P, Yuan B, Withers M, Jhangiani SN, Kalra D, Walker K, English AC, Han Y, Chen K, Muzny DM, Ira G, Shaw CA, Gibbs RA, Hastings PJ, Lupski JR.

Cell. 2019 Mar 7;176(6):1310-1324.e10. doi: 10.1016/j.cell.2019.01.045. Epub 2019 Feb 28.

PMID:
30827684
2.

Pooled extracellular receptor-ligand interaction screening using CRISPR activation.

Chong ZS, Ohnishi S, Yusa K, Wright GJ.

Genome Biol. 2018 Nov 26;19(1):205. doi: 10.1186/s13059-018-1581-3.

3.

Cutting Forces Measurement for Milling Process by Using Working Tables with Integrated PVDF Thin-Film Sensors.

Luo M, Chong Z, Liu D.

Sensors (Basel). 2018 Nov 19;18(11). pii: E4031. doi: 10.3390/s18114031.

4.

A modified DAW-22 compound F-B1 inhibits Bcr/Abl and induces apoptosis in chronic myelogenous leukemia cells.

Wang F, Wang J, Chong Z, Mu Y.

Anticancer Drugs. 2019 Feb;30(2):159-166. doi: 10.1097/CAD.0000000000000712.

PMID:
30422832
5.

Combining accurate tumor genome simulation with crowdsourcing to benchmark somatic structural variant detection.

Lee AY, Ewing AD, Ellrott K, Hu Y, Houlahan KE, Bare JC, Espiritu SMG, Huang V, Dang K, Chong Z, Caloian C, Yamaguchi TN; ICGC-TCGA DREAM Somatic Mutation Calling Challenge Participants, Kellen MR, Chen K, Norman TC, Friend SH, Guinney J, Stolovitzky G, Haussler D, Margolin AA, Stuart JM, Boutros PC.

Genome Biol. 2018 Nov 6;19(1):188. doi: 10.1186/s13059-018-1539-5.

6.

E3 ligase FBXW7 aggravates TMPD-induced systemic lupus erythematosus by promoting cell apoptosis.

Chong Z, Bao C, He J, Chen T, Zhong L, Li G, Li H, Fang L, Song Y, Fu G, Yang X, Lai L, Liu Y, Wang Q.

Cell Mol Immunol. 2018 Dec;15(12):1057-1070. doi: 10.1038/s41423-018-0167-z. Epub 2018 Oct 1.

PMID:
30275535
7.

Structural Variant Breakpoint Detection with novoBreak.

Chong Z, Chen K.

Methods Mol Biol. 2018;1833:129-141. doi: 10.1007/978-1-4939-8666-8_10.

PMID:
30039369
8.

Regenerative Potential of Neonatal Porcine Hearts.

Zhu W, Zhang E, Zhao M, Chong Z, Fan C, Tang Y, Hunter JD, Borovjagin AV, Walcott GP, Chen JY, Qin G, Zhang J.

Circulation. 2018 Dec 11;138(24):2809-2816. doi: 10.1161/CIRCULATIONAHA.118.034886.

PMID:
30030418
9.

In vivo screening identifies GATAD2B as a metastasis driver in KRAS-driven lung cancer.

Grzeskowiak CL, Kundu ST, Mo X, Ivanov AA, Zagorodna O, Lu H, Chapple RH, Tsang YH, Moreno D, Mosqueda M, Eterovic K, Fradette JJ, Ahmad S, Chen F, Chong Z, Chen K, Creighton CJ, Fu H, Mills GB, Gibbons DL, Scott KL.

Nat Commun. 2018 Jul 16;9(1):2732. doi: 10.1038/s41467-018-04572-3.

10.

Mushroom extract inhibits ultraviolet B-induced cellular senescence in human keratinocytes.

Chong Z, Matsuo H, Kuroda M, Yamashita S, Parajuli GP, Manandhar HK, Shimizu K, Katakura Y.

Cytotechnology. 2018 Jun;70(3):1001-1008. doi: 10.1007/s10616-018-0229-1. Epub 2018 Jun 2.

PMID:
29860669
11.

The architecture of the OmpC-MlaA complex sheds light on the maintenance of outer membrane lipid asymmetry in Escherichia coli.

Yeow J, Tan KW, Holdbrook DA, Chong ZS, Marzinek JK, Bond PJ, Chng SS.

J Biol Chem. 2018 Jul 20;293(29):11325-11340. doi: 10.1074/jbc.RA118.002441. Epub 2018 May 30.

PMID:
29848551
12.

Marker chromosome genomic structure and temporal origin implicate a chromoanasynthesis event in a family with pleiotropic psychiatric phenotypes.

Grochowski CM, Gu S, Yuan B, Tcw J, Brennand KJ, Sebat J, Malhotra D, McCarthy S, Rudolph U, Lindstrand A, Chong Z, Levy DL, Lupski JR, Carvalho CMB.

Hum Mutat. 2018 Jul;39(7):939-946. doi: 10.1002/humu.23537. Epub 2018 May 11.

PMID:
29696747
13.

Methanogenic capacity and robustness of hydrogenotrophic cultures based on closed nutrient recycling via microbial catabolism: Impact of temperature and microbial attachment.

Savvas S, Donnelly J, Patterson T, Chong ZS, Esteves SR.

Bioresour Technol. 2018 Jun;257:164-171. doi: 10.1016/j.biortech.2018.02.109. Epub 2018 Feb 24.

PMID:
29500950
14.

Evaluation of the acute and chronic toxicity of the jiangu capsules.

Lan Z, Wang L, Chong Z, Yang G, Yu X, Chen L, Zhou J.

Exp Ther Med. 2017 Dec;14(6):6229-6237. doi: 10.3892/etm.2017.5341. Epub 2017 Oct 18.

15.

A review of S100 protein family in lung cancer.

Wang T, Huo X, Chong Z, Khan H, Liu R, Wang T.

Clin Chim Acta. 2018 Jan;476:54-59. doi: 10.1016/j.cca.2017.11.010. Epub 2017 Nov 13. Review.

PMID:
29146477
16.

MCE domain proteins: conserved inner membrane lipid-binding proteins required for outer membrane homeostasis.

Isom GL, Davies NJ, Chong ZS, Bryant JA, Jamshad M, Sharif M, Cunningham AF, Knowles TJ, Chng SS, Cole JA, Henderson IR.

Sci Rep. 2017 Aug 17;7(1):8608. doi: 10.1038/s41598-017-09111-6.

17.

Heparanase promotes neuroinflammatory response during subarachnoid hemorrhage in rats.

Changyaleket B, Chong ZZ, Dull RO, Nanegrungsunk D, Xu H.

J Neuroinflammation. 2017 Jul 18;14(1):137. doi: 10.1186/s12974-017-0912-8.

18.

A murine preclinical syngeneic transplantation model for breast cancer precision medicine.

Federico L, Chong Z, Zhang D, McGrail DJ, Zhao W, Jeong KJ, Vellano CP, Ju Z, Gagea M, Liu S, Mitra S, Dennison JB, Lorenzi PL, Cardnell R, Diao L, Wang J, Lu Y, Byers LA, Perou CM, Lin SY, Mills GB.

Sci Adv. 2017 Apr 19;3(4):e1600957. doi: 10.1126/sciadv.1600957. eCollection 2017 Apr.

19.

E3 ligase FBXW7 is critical for RIG-I stabilization during antiviral responses.

Song Y, Lai L, Chong Z, He J, Zhang Y, Xue Y, Xie Y, Chen S, Dong P, Chen L, Chen Z, Dai F, Wan X, Xiao P, Cao X, Liu Y, Wang Q.

Nat Commun. 2017 Mar 13;8:14654. doi: 10.1038/ncomms14654.

20.

An Organismal CNV Mutator Phenotype Restricted to Early Human Development.

Liu P, Yuan B, Carvalho CMB, Wuster A, Walter K, Zhang L, Gambin T, Chong Z, Campbell IM, Coban Akdemir Z, Gelowani V, Writzl K, Bacino CA, Lindsay SJ, Withers M, Gonzaga-Jauregui C, Wiszniewska J, Scull J, Stankiewicz P, Jhangiani SN, Muzny DM, Zhang F, Chen K, Gibbs RA, Rautenstrauss B, Cheung SW, Smith J, Breman A, Shaw CA, Patel A, Hurles ME, Lupski JR.

Cell. 2017 Feb 23;168(5):830-842.e7. doi: 10.1016/j.cell.2017.01.037.

21.

The Role of HMGB1 in Pial Arteriole Dilating Reactivity following Subarachnoid Hemorrhage in Rats.

Xu H, Changyaleket B, Valyi-Nagy T, Dull RO, Pelligrino DA, Schwartz DE, Chong ZZ.

J Vasc Res. 2016;53(5-6):349-357. doi: 10.1159/000452412. Epub 2016 Dec 21.

PMID:
27997923
22.

novoBreak: local assembly for breakpoint detection in cancer genomes.

Chong Z, Ruan J, Gao M, Zhou W, Chen T, Fan X, Ding L, Lee AY, Boutros P, Chen J, Chen K.

Nat Methods. 2017 Jan;14(1):65-67. doi: 10.1038/nmeth.4084. Epub 2016 Nov 28.

23.

RhoA regulates resistance to irinotecan by regulating membrane transporter and apoptosis signaling in colorectal cancer.

Ruihua H, Mengyi Z, Chong Z, Meng Q, Xin M, Qiulin T, Feng B, Ming L.

Oncotarget. 2016 Dec 27;7(52):87136-87146. doi: 10.18632/oncotarget.13548.

24.

Single-cell isolation by a modular single-cell pipette for RNA-sequencing.

Zhang K, Gao M, Chong Z, Li Y, Han X, Chen R, Qin L.

Lab Chip. 2016 Nov 29;16(24):4742-4748.

25.

Recombinant human erythropoietin improves functional recovery in patients with severe traumatic brain injury: A randomized, double blind and controlled clinical trial.

Li ZM, Xiao YL, Zhu JX, Geng FY, Guo CJ, Chong ZL, Wang LX.

Clin Neurol Neurosurg. 2016 Nov;150:80-83. doi: 10.1016/j.clineuro.2016.09.001. Epub 2016 Sep 3.

PMID:
27611985
26.

A comparative study between xerographic, computer-assisted overlay generation and animated-superimposition methods in bite mark analyses.

Tai MW, Chong ZF, Asif MK, Rahmat RA, Nambiar P.

Leg Med (Tokyo). 2016 Sep;22:42-8. doi: 10.1016/j.legalmed.2016.07.009. Epub 2016 Jul 30.

PMID:
27591538
27.

Patterns and Impact of Hypoglycemia, Hyperglycemia, and Glucose Variability on Inpatients with Insulin-Treated Cystic Fibrosis-Related Diabetes.

Jones GC, Chong ZM, Gilmour J, Matheson C, MacGregor G, Sainsbury CA.

Diabetes Ther. 2016 Sep;7(3):575-82. doi: 10.1007/s13300-016-0194-7. Epub 2016 Aug 22.

28.

S100B raises the alert in subarachnoid hemorrhage.

Chong ZZ.

Rev Neurosci. 2016 Oct 1;27(7):745-759. doi: 10.1515/revneuro-2016-0021. Review.

PMID:
27442365
29.

Hotspot mutations delineating diverse mutational signatures and biological utilities across cancer types.

Chen T, Wang Z, Zhou W, Chong Z, Meric-Bernstam F, Mills GB, Chen K.

BMC Genomics. 2016 Jun 23;17 Suppl 2:394. doi: 10.1186/s12864-016-2727-x.

30.

RNAi Reveals Phase-Specific Global Regulators of Human Somatic Cell Reprogramming.

Toh CX, Chan JW, Chong ZS, Wang HF, Guo HC, Satapathy S, Ma D, Goh GY, Khattar E, Yang L, Tergaonkar V, Chang YT, Collins JJ, Daley GQ, Wee KB, Farran CA, Li H, Lim YP, Bard FA, Loh YH.

Cell Rep. 2016 Jun 21;15(12):2597-607. doi: 10.1016/j.celrep.2016.05.049. Epub 2016 Jun 9.

31.

Delayed activation of human microglial cells by high dose ionizing radiation.

Chen H, Chong ZZ, De Toledo SM, Azzam EI, Elkabes S, Souayah N.

Brain Res. 2016 Sep 1;1646:193-198. doi: 10.1016/j.brainres.2016.06.002. Epub 2016 Jun 2.

PMID:
27265419
32.

AC electric field induced droplet deformation in a microfluidic T-junction.

Xi HD, Guo W, Leniart M, Chong ZZ, Tan SH.

Lab Chip. 2016 Aug 2;16(16):2982-6. doi: 10.1039/c6lc00448b.

PMID:
27173587
33.

Targeting PRAS40 for multiple diseases.

Chong ZZ.

Drug Discov Today. 2016 Aug;21(8):1222-31. doi: 10.1016/j.drudis.2016.04.005. Epub 2016 Apr 13. Review.

PMID:
27086010
34.

Identifying S100B as a Biomarker and a Therapeutic Target For Brain Injury and Multiple Diseases.

Chong ZZ, Changyaleket B, Xu H, Dull RO, Schwartz DE.

Curr Med Chem. 2016;23(15):1571-96. Review.

PMID:
27048377
35.

A first for health care education.

Chong Z.

CMAJ. 2016 Oct 4;188(14):E335. Epub 2016 Mar 29. No abstract available.

36.

Alberta plans change in doctor compensation.

Chong Z.

CMAJ. 2016 Apr 5;188(6):E101-2. doi: 10.1503/cmaj.109-5240. Epub 2016 Mar 7. No abstract available.

37.

Functional annotation of rare gene aberration drivers of pancreatic cancer.

Tsang YH, Dogruluk T, Tedeschi PM, Wardwell-Ozgo J, Lu H, Espitia M, Nair N, Minelli R, Chong Z, Chen F, Chang QE, Dennison JB, Dogruluk A, Li M, Ying H, Bertino JR, Gingras MC, Ittmann M, Kerrigan J, Chen K, Creighton CJ, Eterovic K, Mills GB, Scott KL.

Nat Commun. 2016 Jan 25;7:10500. doi: 10.1038/ncomms10500.

38.

Intracerebroventricular application of S100B selectively impairs pial arteriolar dilating function in rats.

Changyaleket B, Xu H, Vetri F, Valyi-Nagy T, Paisansathan C, Chong ZZ, Pelligrino DA, Testai FD.

Brain Res. 2016 Mar 1;1634:171-178. doi: 10.1016/j.brainres.2015.12.061. Epub 2016 Jan 7.

PMID:
26773687
39.

Identification of Variant-Specific Functions of PIK3CA by Rapid Phenotyping of Rare Mutations.

Dogruluk T, Tsang YH, Espitia M, Chen F, Chen T, Chong Z, Appadurai V, Dogruluk A, Eterovic AK, Bonnen PE, Creighton CJ, Chen K, Mills GB, Scott KL.

Cancer Res. 2015 Dec 15;75(24):5341-54. doi: 10.1158/0008-5472.CAN-15-1654. Epub 2015 Dec 1.

40.

Active droplet generation in microfluidics.

Chong ZZ, Tan SH, Gañán-Calvo AM, Tor SB, Loh NH, Nguyen NT.

Lab Chip. 2016 Jan 7;16(1):35-58. doi: 10.1039/c5lc01012h. Review.

PMID:
26555381
41.

TransVar: a multilevel variant annotator for precision genomics.

Zhou W, Chen T, Chong Z, Rohrdanz MA, Melott JM, Wakefield C, Zeng J, Weinstein JN, Meric-Bernstam F, Mills GB, Chen K.

Nat Methods. 2015 Nov;12(11):1002-3. doi: 10.1038/nmeth.3622. No abstract available.

42.

Pretest of the clinical application of a management model for comprehensive treatments of acute spinal cord injury.

Zhang R, Chen Q, Xiao Y, Chong Z.

Int J Clin Exp Pathol. 2015 Aug 1;8(8):9342-50. eCollection 2015.

43.

Construction and evaluation of the novel DNA vaccine harboring the inhibin α (1-32) and the RF-amide related peptide-3 genes for improving fertility in mice.

Dan X, Han L, Riaz H, Luo X, Liu X, Chong Z, Yang L.

Exp Anim. 2016;65(1):17-25. doi: 10.1538/expanim.15-0044. Epub 2015 Oct 2.

44.

An integrated map of structural variation in 2,504 human genomes.

Sudmant PH, Rausch T, Gardner EJ, Handsaker RE, Abyzov A, Huddleston J, Zhang Y, Ye K, Jun G, Fritz MH, Konkel MK, Malhotra A, Stütz AM, Shi X, Casale FP, Chen J, Hormozdiari F, Dayama G, Chen K, Malig M, Chaisson MJP, Walter K, Meiers S, Kashin S, Garrison E, Auton A, Lam HYK, Mu XJ, Alkan C, Antaki D, Bae T, Cerveira E, Chines P, Chong Z, Clarke L, Dal E, Ding L, Emery S, Fan X, Gujral M, Kahveci F, Kidd JM, Kong Y, Lameijer EW, McCarthy S, Flicek P, Gibbs RA, Marth G, Mason CE, Menelaou A, Muzny DM, Nelson BJ, Noor A, Parrish NF, Pendleton M, Quitadamo A, Raeder B, Schadt EE, Romanovitch M, Schlattl A, Sebra R, Shabalin AA, Untergasser A, Walker JA, Wang M, Yu F, Zhang C, Zhang J, Zheng-Bradley X, Zhou W, Zichner T, Sebat J, Batzer MA, McCarroll SA; 1000 Genomes Project Consortium, Mills RE, Gerstein MB, Bashir A, Stegle O, Devine SE, Lee C, Eichler EE, Korbel JO.

Nature. 2015 Oct 1;526(7571):75-81. doi: 10.1038/nature15394.

45.

Osmoporin OmpC forms a complex with MlaA to maintain outer membrane lipid asymmetry in Escherichia coli.

Chong ZS, Woo WF, Chng SS.

Mol Microbiol. 2015 Dec;98(6):1133-46. doi: 10.1111/mmi.13202. Epub 2015 Sep 25.

46.

Amantadine inhibits cellular proliferation and induces the apoptosis of hepatocellular cancer cells in vitro.

Lan Z, Chong Z, Liu C, Feng D, Fang D, Zang W, Zhou J.

Int J Mol Med. 2015 Sep;36(3):904-10. doi: 10.3892/ijmm.2015.2289. Epub 2015 Jul 20.

PMID:
26201988
47.

ClinSeK: a targeted variant characterization framework for clinical sequencing.

Zhou W, Zhao H, Chong Z, Mark RJ, Eterovic AK, Meric-Bernstam F, Chen K.

Genome Med. 2015 Mar 31;7(1):34. doi: 10.1186/s13073-015-0155-1. eCollection 2015.

48.

mTOR: A Novel Therapeutic Target for Diseases of Multiple Systems.

Chong ZZ.

Curr Drug Targets. 2015;16(10):1107-32. Review.

PMID:
25850623
49.

Genome-wide 5-hydroxymethylcytosine modification pattern is a novel epigenetic feature of globozoospermia.

Wang XX, Sun BF, Jiao J, Chong ZC, Chen YS, Wang XL, Zhao Y, Zhou YM, Li D.

Oncotarget. 2015 Mar 30;6(9):6535-43.

50.

Disruption of follistatin by RNAi increases apoptosis, arrests S-phase of cell cycle and decreases estradiol production in bovine granulosa cells.

Chong Z, Dong P, Riaz H, Shi L, Yu X, Cheng Y, Yang L.

Anim Reprod Sci. 2015 Apr;155:80-8. doi: 10.1016/j.anireprosci.2015.02.003. Epub 2015 Feb 12.

PMID:
25728901

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