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J Clin Microbiol. 2000 Jun;38(6):2386-8.

Epidemiology of recurrences or reinfections of Clostridium difficile-associated diarrhea.

Author information

1
Department of Microbiology, Hôpital Saint-Antoine, Assistance Publique-Hôpitaux de Paris, Paris, France. frederic.barbut@sat.ap-hop-paris.fr

Abstract

Approximately 15 to 35% of patients with a first episode of Clostridium difficile-associated diarrhea relapse within 2 months. Between 1994 and 1997, strains from 93 hospitalized patients with C. difficile recurrences were fingerprinted by using both serotyping and PCR-ribotyping. The results showed that 48.4% of clinical recurrences were, in fact, reinfections with a different strain of C. difficile. Rates of clinical recurrences could therefore be reduced by implementing strict isolation precautions.

PMID:
10835010
PMCID:
PMC86814
[Indexed for MEDLINE]
Free PMC Article

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