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Items: 14


A Two-Component System Regulates Bacteroides fragilis Toxin to Maintain Intestinal Homeostasis and Prevent Lethal Disease.

Hecht AL, Casterline BW, Choi VM, Bubeck Wardenburg J.

Cell Host Microbe. 2017 Oct 11;22(4):443-448.e5. doi: 10.1016/j.chom.2017.08.007. Epub 2017 Sep 21.


The Bacteroides fragilis pathogenicity island links virulence and strain competition.

Casterline BW, Hecht AL, Choi VM, Bubeck Wardenburg J.

Gut Microbes. 2017 Jul 4;8(4):374-383. doi: 10.1080/19490976.2017.1290758. Epub 2017 Feb 23.


Activation Mechanism of the Bacteroides fragilis Cysteine Peptidase, Fragipain.

Herrou J, Choi VM, Bubeck Wardenburg J, Crosson S.

Biochemistry. 2016 Jul 26;55(29):4077-84. doi: 10.1021/acs.biochem.6b00546. Epub 2016 Jul 12.


Activation of Bacteroides fragilis toxin by a novel bacterial protease contributes to anaerobic sepsis in mice.

Choi VM, Herrou J, Hecht AL, Teoh WP, Turner JR, Crosson S, Bubeck Wardenburg J.

Nat Med. 2016 May;22(5):563-7. doi: 10.1038/nm.4077. Epub 2016 Apr 18.


Zinc-finger nuclease-driven targeted integration into mammalian genomes using donors with limited chromosomal homology.

Orlando SJ, Santiago Y, DeKelver RC, Freyvert Y, Boydston EA, Moehle EA, Choi VM, Gopalan SM, Lou JF, Li J, Miller JC, Holmes MC, Gregory PD, Urnov FD, Cost GJ.

Nucleic Acids Res. 2010 Aug;38(15):e152. doi: 10.1093/nar/gkq512. Epub 2010 Jun 8.


Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome.

DeKelver RC, Choi VM, Moehle EA, Paschon DE, Hockemeyer D, Meijsing SH, Sancak Y, Cui X, Steine EJ, Miller JC, Tam P, Bartsevich VV, Meng X, Rupniewski I, Gopalan SM, Sun HC, Pitz KJ, Rock JM, Zhang L, Davis GD, Rebar EJ, Cheeseman IM, Yamamoto KR, Sabatini DM, Jaenisch R, Gregory PD, Urnov FD.

Genome Res. 2010 Aug;20(8):1133-42. doi: 10.1101/gr.106773.110. Epub 2010 May 27.


Transient cold shock enhances zinc-finger nuclease-mediated gene disruption.

Doyon Y, Choi VM, Xia DF, Vo TD, Gregory PD, Holmes MC.

Nat Methods. 2010 Jun;7(6):459-60. doi: 10.1038/nmeth.1456. Epub 2010 May 2.


BMP antagonists and FGF signaling contribute to different domains of the neural plate in Xenopus.

Wills AE, Choi VM, Bennett MJ, Khokha MK, Harland RM.

Dev Biol. 2010 Jan 15;337(2):335-50. doi: 10.1016/j.ydbio.2009.11.008. Epub 2009 Nov 10.


Knockout rats via embryo microinjection of zinc-finger nucleases.

Geurts AM, Cost GJ, Freyvert Y, Zeitler B, Miller JC, Choi VM, Jenkins SS, Wood A, Cui X, Meng X, Vincent A, Lam S, Michalkiewicz M, Schilling R, Foeckler J, Kalloway S, Weiler H, Ménoret S, Anegon I, Davis GD, Zhang L, Rebar EJ, Gregory PD, Urnov FD, Jacob HJ, Buelow R.

Science. 2009 Jul 24;325(5939):433. doi: 10.1126/science.1172447.


Chromosomal translocations induced at specified loci in human stem cells.

Brunet E, Simsek D, Tomishima M, DeKelver R, Choi VM, Gregory P, Urnov F, Weinstock DM, Jasin M.

Proc Natl Acad Sci U S A. 2009 Jun 30;106(26):10620-5. doi: 10.1073/pnas.0902076106. Epub 2009 Jun 23.


Precise genome modification in the crop species Zea mays using zinc-finger nucleases.

Shukla VK, Doyon Y, Miller JC, DeKelver RC, Moehle EA, Worden SE, Mitchell JC, Arnold NL, Gopalan S, Meng X, Choi VM, Rock JM, Wu YY, Katibah GE, Zhifang G, McCaskill D, Simpson MA, Blakeslee B, Greenwalt SA, Butler HJ, Hinkley SJ, Zhang L, Rebar EJ, Gregory PD, Urnov FD.

Nature. 2009 May 21;459(7245):437-41. doi: 10.1038/nature07992. Epub 2009 Apr 29.


Developmental expression of FoxJ1.2, FoxJ2, and FoxQ1 in Xenopus tropicalis.

Choi VM, Harland RM, Khokha MK.

Gene Expr Patterns. 2006 Jun;6(5):443-7. Epub 2006 Feb 7.


The statistical variability of blood alcohol concentration measurements in drink-driving cases.

Fung WK, Chan KL, Mok VK, Lee CW, Choi VM.

Forensic Sci Int. 2000 Jun 5;110(3):207-14.


Small bowel permeability--a variable effect of NSAIDS.

Choi VM, Coates JE, Chooi J, Thomson AB, Russell AS.

Clin Invest Med. 1995 Oct;18(5):357-61.


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