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Items: 47

1.

The exonuclease Xrn1 activates transcription and translation of mRNAs encoding membrane proteins.

Blasco-Moreno B, de Campos-Mata L, Böttcher R, García-Martínez J, Jungfleisch J, Nedialkova DD, Chattopadhyay S, Gas ME, Oliva B, Pérez-Ortín JE, Leidel SA, Choder M, Díez J.

Nat Commun. 2019 Mar 21;10(1):1298. doi: 10.1038/s41467-019-09199-6.

2.

Dissociation of Rpb4 from RNA polymerase II is important for yeast functionality.

Duek L, Barkai O, Elran R, Adawi I, Choder M.

PLoS One. 2018 Oct 25;13(10):e0206161. doi: 10.1371/journal.pone.0206161. eCollection 2018.

3.

Pheromone-encoding mRNA is transported to the yeast mating projection by specific RNP granules.

Aronov S, Dover-Biterman S, Suss-Toby E, Shmoish M, Duek L, Choder M.

J Cell Biol. 2015 Jun 22;209(6):829-42. doi: 10.1083/jcb.201408045.

4.

Conceptual modeling of mRNA decay provokes new hypotheses.

Somekh J, Haimovich G, Guterman A, Dori D, Choder M.

PLoS One. 2014 Sep 25;9(9):e107085. doi: 10.1371/journal.pone.0107085. eCollection 2014. Erratum in: PLoS One. 2014;9(12):e114961.

5.

Cytoplasmic 5'-3' exonuclease Xrn1p is also a genome-wide transcription factor in yeast.

Medina DA, Jordán-Pla A, Millán-Zambrano G, Chávez S, Choder M, Pérez-Ortín JE.

Front Genet. 2014 Feb 6;5:1. doi: 10.3389/fgene.2014.00001. eCollection 2014.

6.

Gene expression is circular: factors for mRNA degradation also foster mRNA synthesis.

Haimovich G, Medina DA, Causse SZ, Garber M, Millán-Zambrano G, Barkai O, Chávez S, Pérez-Ortín JE, Darzacq X, Choder M.

Cell. 2013 May 23;153(5):1000-11. doi: 10.1016/j.cell.2013.05.012.

7.

Eukaryotic mRNA decay: methodologies, pathways, and links to other stages of gene expression.

Pérez-Ortín JE, Alepuz P, Chávez S, Choder M.

J Mol Biol. 2013 Oct 23;425(20):3750-75. doi: 10.1016/j.jmb.2013.02.029. Epub 2013 Mar 4. Review.

PMID:
23467123
8.

The fate of the messenger is pre-determined: a new model for regulation of gene expression.

Haimovich G, Choder M, Singer RH, Trcek T.

Biochim Biophys Acta. 2013 Jun-Jul;1829(6-7):643-53. doi: 10.1016/j.bbagrm.2013.01.004. Epub 2013 Jan 19. Review.

9.

Conceptual Model-based Systems Biology: mapping knowledge and discovering gaps in the mRNA transcription cycle.

Somekh J, Choder M, Dori D.

PLoS One. 2012 Dec 20;7(12):e51430. doi: 10.1371/journal.pone.0051430. Epub 2012 Dec 20.

10.

The eukaryotic transcriptional machinery regulates mRNA translation and decay in the cytoplasm.

Dahan N, Choder M.

Biochim Biophys Acta. 2013 Jan;1829(1):169-73. doi: 10.1016/j.bbagrm.2012.08.004. Epub 2012 Sep 6. Review.

PMID:
22982191
11.

Promoter elements regulate cytoplasmic mRNA decay.

Bregman A, Avraham-Kelbert M, Barkai O, Duek L, Guterman A, Choder M.

Cell. 2011 Dec 23;147(7):1473-83. doi: 10.1016/j.cell.2011.12.005.

12.

Transcriptome kinetics is governed by a genome-wide coupling of mRNA production and degradation: a role for RNA Pol II.

Shalem O, Groisman B, Choder M, Dahan O, Pilpel Y.

PLoS Genet. 2011 Sep;7(9):e1002273. doi: 10.1371/journal.pgen.1002273. Epub 2011 Sep 8. Erratum in: PLoS Genet. 2011 Sep;7(9). doi: 10.1371/annotation/7919492c-3e4b-4363-96da-f75281c1340c.

13.
14.

RNA polymerase II subunits link transcription and mRNA decay to translation.

Harel-Sharvit L, Eldad N, Haimovich G, Barkai O, Duek L, Choder M.

Cell. 2010 Nov 12;143(4):552-63. doi: 10.1016/j.cell.2010.10.033.

15.

A novel c-Jun N-terminal kinase (JNK)-binding protein WDR62 is recruited to stress granules and mediates a nonclassical JNK activation.

Wasserman T, Katsenelson K, Daniliuc S, Hasin T, Choder M, Aronheim A.

Mol Biol Cell. 2010 Jan 1;21(1):117-30. doi: 10.1091/mbc.E09-06-0512. Epub 2009 Nov 12.

16.

Transcription in the nucleus and mRNA decay in the cytoplasm are coupled processes.

Goler-Baron V, Selitrennik M, Barkai O, Haimovich G, Lotan R, Choder M.

Genes Dev. 2008 Aug 1;22(15):2022-7. doi: 10.1101/gad.473608.

17.

Alopecia, neurological defects, and endocrinopathy syndrome caused by decreased expression of RBM28, a nucleolar protein associated with ribosome biogenesis.

Nousbeck J, Spiegel R, Ishida-Yamamoto A, Indelman M, Shani-Adir A, Adir N, Lipkin E, Bercovici S, Geiger D, van Steensel MA, Steijlen PM, Bergman R, Bindereif A, Choder M, Shalev S, Sprecher E.

Am J Hum Genet. 2008 May;82(5):1114-21. doi: 10.1016/j.ajhg.2008.03.014. Epub 2008 Apr 24.

18.

SERKAL syndrome: an autosomal-recessive disorder caused by a loss-of-function mutation in WNT4.

Mandel H, Shemer R, Borochowitz ZU, Okopnik M, Knopf C, Indelman M, Drugan A, Tiosano D, Gershoni-Baruch R, Choder M, Sprecher E.

Am J Hum Genet. 2008 Jan;82(1):39-47. doi: 10.1016/j.ajhg.2007.08.005.

19.

The Rpb7p subunit of yeast RNA polymerase II plays roles in the two major cytoplasmic mRNA decay mechanisms.

Lotan R, Goler-Baron V, Duek L, Haimovich G, Choder M.

J Cell Biol. 2007 Sep 24;178(7):1133-43. Epub 2007 Sep 17.

20.
21.

Nucleocytoplasmic shuttling of the Rpb4p and Rpb7p subunits of Saccharomyces cerevisiae RNA polymerase II by two pathways.

Selitrennik M, Duek L, Lotan R, Choder M.

Eukaryot Cell. 2006 Dec;5(12):2092-103. Epub 2006 Oct 20.

22.

A deleterious mutation in SAMD9 causes normophosphatemic familial tumoral calcinosis.

Topaz O, Indelman M, Chefetz I, Geiger D, Metzker A, Altschuler Y, Choder M, Bercovich D, Uitto J, Bergman R, Richard G, Sprecher E.

Am J Hum Genet. 2006 Oct;79(4):759-64. Epub 2006 Aug 24.

23.

The RNA polymerase II subunit Rpb4p mediates decay of a specific class of mRNAs.

Lotan R, Bar-On VG, Harel-Sharvit L, Duek L, Melamed D, Choder M.

Genes Dev. 2005 Dec 15;19(24):3004-16.

24.

Rpb4 and Rpb7: subunits of RNA polymerase II and beyond.

Choder M.

Trends Biochem Sci. 2004 Dec;29(12):674-81. Review.

PMID:
15544954
25.

Rpb4p, a subunit of RNA polymerase II, mediates mRNA export during stress.

Farago M, Nahari T, Hammel C, Cole CN, Choder M.

Mol Biol Cell. 2003 Jul;14(7):2744-55.

27.

Rapamycin blocks sexual development in fission yeast through inhibition of the cellular function of an FKBP12 homolog.

Weisman R, Finkelstein S, Choder M.

J Biol Chem. 2001 Jul 6;276(27):24736-42. Epub 2001 May 2.

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30.

Glucose starvation induces a drastic reduction in the rates of both transcription and degradation of mRNA in yeast.

Jona G, Choder M, Gileadi O.

Biochim Biophys Acta. 2000 Apr 25;1491(1-3):37-48.

PMID:
10760568
31.
32.

Monitoring dynamics of gene expression in yeast during stationary phase.

Paz I, Meunier JR, Choder M.

Gene. 1999 Aug 5;236(1):33-42.

PMID:
10433964
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41.

Cloning and functional analysis of the arginyl-tRNA-protein transferase gene ATE1 of Saccharomyces cerevisiae.

Balzi E, Choder M, Chen WN, Varshavsky A, Goffeau A.

J Biol Chem. 1990 May 5;265(13):7464-71.

42.

Transcription termination in animal viruses and cells.

Resnekov O, Ben-Asher E, Bengal E, Choder M, Hay N, Kessler M, Ragimov N, Seiberg M, Skolnik-David H, Aloni Y.

Gene. 1988 Dec 10;72(1-2):91-104.

PMID:
2854091
45.

Curved DNA: design, synthesis, and circularization.

Ulanovsky L, Bodner M, Trifonov EN, Choder M.

Proc Natl Acad Sci U S A. 1986 Feb;83(4):862-6.

47.

Synthesis of carrier-free beta-32P-nucleosides-triphosphate in almost quantitative yields.

Kaufmann G, Choder M, Groner Y.

Anal Biochem. 1980 Nov 15;109(1):198-202. No abstract available.

PMID:
7008646

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