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Items: 10


Staphylococcus aureus Coproporphyrinogen III Oxidase Is Required for Aerobic and Anaerobic Heme Synthesis.

Choby JE, Skaar EP.

mSphere. 2019 Jul 10;4(4). pii: e00235-19. doi: 10.1128/mSphere.00235-19.


Control of Metabolite Flux during the Final Steps of Heme b Biosynthesis in Gram-Positive Bacteria.

Celis AI, Choby JE, Kentro J, Skaar EP, DuBois JL.

Biochemistry. 2019 Jun 26. doi: 10.1021/acs.biochem.9b00140. [Epub ahead of print]


Manganese Detoxification by MntE Is Critical for Resistance to Oxidative Stress and Virulence of Staphylococcus aureus.

Grunenwald CM, Choby JE, Juttukonda LJ, Beavers WN, Weiss A, Torres VJ, Skaar EP.

MBio. 2019 Feb 26;10(1). pii: e02915-18. doi: 10.1128/mBio.02915-18.


A Phenome-Wide Association Study Uncovers a Pathological Role of Coagulation Factor X during Acinetobacter baumannii Infection.

Choby JE, Monteith AJ, Himmel LE, Margaritis P, Shirey-Rice JK, Pruijssers A, Jerome RN, Pulley J, Skaar EP.

Infect Immun. 2019 Apr 23;87(5). pii: e00031-19. doi: 10.1128/IAI.00031-19. Print 2019 Mar.


Molecular Basis for the Evolution of Species-Specific Hemoglobin Capture by Staphylococcus aureus.

Choby JE, Buechi HB, Farrand AJ, Skaar EP, Barber MF.

MBio. 2018 Nov 20;9(6). pii: e01524-18. doi: 10.1128/mBio.01524-18.


Staphylococcus aureus HemX Modulates Glutamyl-tRNA Reductase Abundance To Regulate Heme Biosynthesis.

Choby JE, Grunenwald CM, Celis AI, Gerdes SY, DuBois JL, Skaar EP.

MBio. 2018 Feb 6;9(1). pii: e02287-17. doi: 10.1128/mBio.02287-17.


A Small-Molecule Inhibitor of Iron-Sulfur Cluster Assembly Uncovers a Link between Virulence Regulation and Metabolism in Staphylococcus aureus.

Choby JE, Mike LA, Mashruwala AA, Dutter BF, Dunman PM, Sulikowski GA, Boyd JM, Skaar EP.

Cell Chem Biol. 2016 Nov 17;23(11):1351-1361. doi: 10.1016/j.chembiol.2016.09.012. Epub 2016 Oct 20.


Heme Synthesis and Acquisition in Bacterial Pathogens.

Choby JE, Skaar EP.

J Mol Biol. 2016 Aug 28;428(17):3408-28. doi: 10.1016/j.jmb.2016.03.018. Epub 2016 Mar 24. Review.


Two-component system cross-regulation integrates Bacillus anthracis response to heme and cell envelope stress.

Mike LA, Choby JE, Brinkman PR, Olive LQ, Dutter BF, Ivan SJ, Gibbs CM, Sulikowski GA, Stauff DL, Skaar EP.

PLoS Pathog. 2014 Mar 27;10(3):e1004044. doi: 10.1371/journal.ppat.1004044. eCollection 2014 Mar.


Targeting glucosylceramide synthase synergizes with C6-ceramide nanoliposomes to induce apoptosis in natural killer cell leukemia.

Watters RJ, Fox TE, Tan SF, Shanmugavelandy S, Choby JE, Broeg K, Liao J, Kester M, Cabot MC, Loughran TP, Liu X.

Leuk Lymphoma. 2013 Jun;54(6):1288-96. doi: 10.3109/10428194.2012.752485. Epub 2012 Dec 31.

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